Clinical trials: Skeletal Muscle
Cerebral Palsy (CP)
Whole Body Metabolism in Children With Cerebral Palsy With Low Skeletal Muscle Mass
At the center of pediatrics in Copenhagen the investigators experience that the children with CP with low skeletal muscle mass have more complications and admission after for example surgery is prolonged due to these…
- Trial name
- NCT06486597
- Testing
- Meal
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Critical Illness, Physical Disability
Neuromuscular Electrical Stimulation (NMES) Preserves Muscle Mass in Intensive Care Unit (ICU)
Background: Low-frequency neuromuscular electrical stimulation (NMES) attenuates the loss of muscle mass of Intensive Care Unit (ICU) patients.
- Conditions
- Critical Illness, Physical Disability, Muscle Atrophy
- Trial name
- NCT05287919
- Testing
- Patients received the standard physical therapy (SPT) programme (passive mobilization) twice a day., Patients received the low-frequency neuromuscular electrical stimulation (NMES), Patients received the medium-frequency neuromuscular electrical stimulation (NMES)
- Where
- Chile
- Volunteers
- 54 people
- Sponsor
- Gabriel Nasri Marzuca-Nassr
Sepsis, Primary Myopathies
Muscle Force Assessment in the Intensive Care Unit and in Primary Myopathies
The primary aim of the project is to apply the non-invasive stimulated muscle force assessment system to i) intensive care unit patients and ii) patients with primary myopathy or subclinic myopathy (e.g., Duchenne muscular…
- Trial name
- NCT00735384
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
COPD Diagnosed
Evaluation of a Simple Clinical Test to Detect the Risk of Falling in Patients With BPCO and Research for Predictive Factors of Fall Risk.
The risk of falling in increased in patients with Chronic Obstructive Pulmonary Disease. To date, a screening test (the Berg Balance scale, BBS) is used to evaluate this risk but it spends 20 to 30 minutes to complete.
- Trial name
- Equil-BPCO (NCT03152344)
- Testing
- Timed Up and Go
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Clermont-Ferrand
Atrophy, Sepsis
Muscle Atrophy in Sepsis
Severe sepsis will provoke signals leading to muscle atrophy and weakness. Electrical stimulation will reduce the impact of sepsis.
- Conditions
- Atrophy, Sepsis, Weakness
- Trial name
- NCT00583206
- Where
- United States
- Sponsor
- Gregory A. Schmidt
Muscle Loss, Physical Disability
Effects of High Protein Diet on Muscle Mass, Strength, and Physical Performance in Postmenopausal Women
Despite the importance of preventing muscle mass loss during senescence, only a few studies have investigated the relationship between diet and muscle mass in postmenopausal women.
- Trial name
- NCT03652584
- Testing
- High Protein Diet, Control Diet
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Aging
Nicotinamide Adenine Dinucleotide and Skeletal Muscle Metabolic Phenotype
This study is designed to assess the physiological consequences of elevating Nicotinamide Adenine Dinucleotide (NAD+) availability using Nicotinamide Riboside (NR) supplementation in skeletal muscle tissue, and examine its effect…
- Trial name
- NADMet (NCT02950441)
- Testing
- Nicotinamide Riboside
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Cancer
Effects of Nutritional Supplementation (Product 4808) on Acute Skeletal Muscle Protein Synthesis in Cancer Patients
The purpose of the study is to compare two different nutritional supplements with respect to their effect on building muscle, and to determine the factors that control the rate at which muscle tissue can be produced in subjects…
- Trial name
- NCT00446888
- Testing
- Standardized Meals for Diet Stabilization, Forticare, Product 4808
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Arkansas
Muscle Loss in Elderly
The Effects of Resistance Training and Protein Supplementation in Healthy Elderly Men and Women.
The main objective of this study is to examine the effects of resistance type exercise training combined with nutritional support on body composition and muscle characteristics in healthy elderly men and women.
- Trial name
- NCT01004588
- Testing
- Protein drink
- Where
- Netherlands
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Sleep Disturbance, Postmenopausal Symptoms
Effect of Sleep Restriction on Adipose Tissue and Skeletal Muscle Insulin Sensitivity
Inadequate sleep is an independent risk factor for metabolic abnormalities (such as obesity, insulin resistance, and hyperglycemia).
- Conditions
- Sleep Disturbance, Postmenopausal Symptoms, Insulin Sensitivity, Cardiovascular Risk Factor
- Trial name
- SLEEP-IN (NCT04286451)
- Testing
- Sleep Restriction, Habitual Sleep
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Physical Inactivity, Vascular Dysfunction
Heat Therapy During Reduced Physical Activity
The purpose of this randomized controlled trial is to determine whether daily Finnish dry sauna therapy attenuates the adverse cardiovascular, muscular, and metabolic effects of seven days of experimentally reduced physical…
- Conditions
- Physical Inactivity, Vascular Dysfunction, Skeletal Muscle Atrophy
- Trial name
- HEAT-RPA (NCT07847424)
- Testing
- Sauna, Reduced Physical Activity
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brigham Young University
Skeletal Muscle Energy Metabolism
The Effect of Omega-3 Fatty Acid Supplementation on Skeletal Muscle Membrane Composition and Cellular Metabolism
The biological membranes that surround a cell and its organelles are vital to the overall function of the cell. Fatty acids are the main structural component of membranes, and the presence of specific fatty acids can alter a…
- Trial name
- NCT01732003
- Testing
- Omega-3 Complete
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Sarcopenia, Cardiovascular Disease
Egg Cholesterol Consumption, Blood Cholesterol and Skeletal Muscle Hypertrophy
The purpose of this study is to examine the effect of dietary cholesterol administered as whole egg or egg white (control)on muscle mass gain with resistance training in a young old population of men and women (age 50-69).
- Trial name
- NCT00260442
- Testing
- Resistance Training, Sedentary
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Rheumatoid Arthritis, Healthy Controls
MusculRA: The Effects of Rheumatoid Arthritis on Skeletal Muscle Biomechanics
Persons with rheumatoid arthritis (RA) suffer from increased disability and mortality, in part resulting from skeletal muscle impairments.
- Trial name
- MusculRA (NCT04226131)
- Testing
- Blood Draw, Disease Activity (DAS-28) Assessment, Skeletal Muscle Mitochondrial Respiratory Capacity
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Duke University
Insulin Resistance
Skeletal Muscle Protein Metabolism and Insulin Sensitivity in Overweight Individuals: Effects of Meals With Various Fatty Acid Compositions
The aim of the study will investigate whether impairment in the action of insulin to promote the use of glucose in skeletal muscle (insulin resistance) as a result of oral ingestion of a liquid meal rich in saturated fat is…
- Trial name
- NCT03146286
- Testing
- Saturated fat, Fish Oil
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
HIV, Obesity
A Study to Improve Skeletal Muscle in Veterans With HIV
The Department of Veterans Affairs is the largest single provider of medical care to people with HIV in the United States. The condition of excess lipid within and around muscle, termed myosteatosis, predisposes Veterans to…
- Trial name
- NCT06845046
- Testing
- w-3 fatty acid, L-carnitine, Control Diet
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- VA Office of Research and Development
Post COVID-19 Syndrome, Functional Inspiratory Muscle Training
Effectiveness of Functional Respiratory Muscle Training in Post-COVID-19 Syndrome
This study aims to investigate the effects of core stabilization exercises and functional inspiratory muscle training (IMT) on various physiological and psychological parameters in individuals with post-COVID-19 syndrome.
- Conditions
- Post COVID-19 Syndrome, Functional Inspiratory Muscle Training, Core Stabilization
- Trial name
- NCT07051954
- Testing
- Core Stabilization, Functional Inspiratory Muscle Training (IMT)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Skeletal Muscle Physiology
Proteome Remodelling
The purpose of the project is to investigate the proteome signature dynamics and remodelling in human skeletal muscle induced by exercise training
- Trial name
- NCT04136457
- Testing
- Endurance training, Resistance training, Sprint training
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
Neck Pain, Shoulder Pain
Neck and Shoulder Pain Research Study
Pain in the neck and shoulders is a musculoskeletal disorder that affects a significant number of individuals.The aim of this study is to evaluate the effects of PBMT (with a device that combines low level laser therapy and light…
- Conditions
- Neck Pain, Shoulder Pain, Chronic Pain, Musculoskeletal Pain
- Trial name
- NCT02940119
- Testing
- Multi Radiance Medical®
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- University of Nove de Julho
Obesity
Mechanisms Underlying Postoperative Insulin Resistance and Inflammation
Having an operation places an enormous burden on the body, leading to the development of inflammation and so called 'insulin resistance'.
- Trial name
- NCT01470534
- Testing
- carbohydrate drink, Muscle biopsy, Blood sampling
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University of Nottingham