Clinical trials: Sinus Tract
Chronic Rhinosinusitis With Nasal Polyps
A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Participants With Chronic Rhinosinusitis With Nasal Polyps
The primary purpose of this study is to assess the effect of verekitug (UPB-101) on the endoscopically determined size and extend of nasal polyps in participants with chronic rhinosinusitis with nasal polyps (CRSwNP) and to…
- Trial name
- VIBRANT (NCT06164704)
- Testing
- Verekitug (UPB-101)
- Where
- 41 sites in United States, Czechia and 3 more
- Volunteers
- 81 people
- Sponsor
- Upstream Bio Inc.
Chronic Sinusitis
Photodynamic Therapy for the Treatment of Chronic Rhinosinusitis
The purpose of this study is to determine whether the use of light and a topically applied photosensitizer can relieve symptoms and clinically improve patients with chronic rhinosinusitis.
- Trial name
- NCT01854619
- Testing
- Photodisinfection (antimicrobial photodynamic therapy, aPDT), Saline irrigation
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Ondine Biomedical Inc.
Sinusitis, Maxillary Sinusitis
A Study of the Safety and Effectiveness of Levofloxacin Compared With Amoxicillin/Clavulanate Potassium in the Treatment of Adults With Rapid Onset of Severe Inflammation/Infection of the Sinuses
The purpose of this study is to evaluate the safety and effectiveness of levofloxacin, an antibiotic, compared with amoxicillin/clavulanate potassium in the treatment of adults with rapid onset of severe inflammation/infection of…
- Trial name
- NCT00249210
- Testing
- levofloxacin
- Volunteers
- 614 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.