Clinical trials: Sinus Surgery
Bleeding
Nasal Desmopressin Versus Oral Bisoprolol for Controlling Bleeding During Endoscopic Sinus Surgery
Functional endoscopic sinus surgery (FESS) is well established for treatment of chronic rhinosinusitis and nasal polyps. Masking of the surgical field can lead to severe complication as tissue injury, increase post-operative…
- Trial name
- NCT05430048
- Testing
- nasal Desmopressin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Zagazig University
Chronic Rhinosinusitis (CRS)
Intra-Sinus Povidone-Iodine and Budesonide After Endoscopic Sinus Surgery for Chronic Rhinosinusitis
Endoscopic sinus surgery (ESS) is commonly performed in patients with chronic rhinosinusitis (CRS) to improve sinus drainage and allow better delivery of topical therapies after surgery.
- Trial name
- PVP-I (NCT07383402)
- Testing
- Povidone-Iodine and Budesonide Gel-Forming Suspension
- Volunteers
- 180 people
- Sponsor
- Amin Javer
Chronic Rhinosinusitis, Rhinosinusitis
Xylitol for Chronic Sinusitis
The purpose of this investigation is to conduct a randomized controlled trial within a subgroup of difficult-to-treat patients with CRS, evaluating the use of topical xylitol treatment concurrently with topical…
- Conditions
- Chronic Rhinosinusitis, Rhinosinusitis, Sinusitis, Drain Sinus
- Trial name
- NCT03229551
- Testing
- Xylitol, Saline
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Head and Neck Cancer, Pain
Acupuncture or Standard Therapy in Treating Pain and Dysfunction in Patients Who Have Undergone Neck Surgery for Head and Neck Cancer
RATIONALE: Acupuncture may help relieve pain and dysfunction caused by cancer surgery. It is not yet known whether acupuncture is more effective than standard therapy in treating pain and dysfunction in patients who have…
- Trial name
- NCT00090337
- Testing
- acupuncture therapy, standard follow-up care
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Chronic Rhinosinusitis
Povidone-Iodine Nasal Irrigation After Surgery for Chronic Rhinosinusitis
This prospective randomized controlled trial evaluates the effectiveness and safety of different nasal irrigation solutions for postoperative care after endoscopic sinus surgery in patients with chronic rhinosinusitis.
- Trial name
- NCT07470242
- Testing
- Normal Saline Nasal Irrigation, Acetylcysteine (Mucomyst) Nasal Irrigation, Povidone-Iodine Nasal Irrigation
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Pusan National University Hospital
Chronic Sinusitis
Safety and Efficacy of the Propel Mini and Propel Nova Steroid-Eluting Sinus Implant in Frontal Sinus
The objective of the PROGRESS Study is to assess the safety and efficacy of the Propel Mini and Propel Nova steroid-eluting Sinus Implants when placed in the frontal sinus opening following frontal sinus surgery in patients with…
- Trial name
- PROGRESS (NCT02266810)
- Testing
- PROPEL Mini Sinus Implant., Sinus Surgery alone, Propel Nova Sinus Implant
- Where
- 10 sites in United States
- Volunteers
- 160 people
- Sponsor
- Intersect ENT
Bile Leak, Anastomotic Leak Biliary
Factors Influencing Occurrence of Bile Leaks in Surgery
The objective of our study is to identify the factors influencing the occurrence of a biliary leak after performing surgery leading to the creation of a biliary anastomosis to any segment of the digestive tract.
- Conditions
- Bile Leak, Anastomotic Leak Biliary, Biliary Tract Fistula
- Trial name
- NCT04665427
- Testing
- bilioenteric anastomosis i
- Where
- Algeria
- Volunteers
- 108 people
- Sponsor
- University of Oran 1
Aminophylline, Dexmedetomidine
Aminophylline on Recovery in Functional Endoscopic Sinus Surgery Under Dexmedetomidine Hypotensive Anesthesia
This study will be conducted to evaluate the effect of intravenous aminophylline on hemodynamics and recovery of patients receiving dexmedetomidine infusion during functional endoscopic sinus surgery.
- Conditions
- Aminophylline, Dexmedetomidine, Functional Endoscopic Sinus Surgery
- Trial name
- NCT05738135
- Testing
- Aminophylline group, normal saline
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tanta University
Surgical Complications
Impact of Pasireotide on Postoperative Pancreatic Fistulas Following Distal Resections
Between 2000 and 2016 258 distal pancreatectomies were performed at our University Hospital which were included in our analysis. Pasireotide was used in between July 2014 and April 2016.
- Trial name
- NCT04281680
- Testing
- Pasireotide 0.9 MG/ML
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Endoscopic Sinus Surgery
Propofol and Magnesium Sulfate Intravenous Infusion During Endoscopic Sinus Surgery
Endoscopic Sinus surgery usually associated by bleeding, despite using of local vasopressor injection, head up position- controlled hypotension is generally used for control of this purpose.
- Trial name
- NCT04078659
- Testing
- Propofol infusion, Magnesium Sulfate infusion, Lidocaine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Advanced Chronic Rhinosinusitis
Total Intravenous Anesthesia in Sinus Surgery
Utilization of total intravenous anesthesia (TIVA) has been proposed as a method to improve visualization during endoscopic sinus surgery (ESS), largely due to its physiologic decrease in cardiac output without the peripheral…
- Trial name
- NCT02578862
- Testing
- Propofol, Sevoflurane
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System