Clinical trials: Sinus Surgery
Nebulization, Intravenous
Nebulized Versus Intravenous Tranexamic Acid on Surgical Field Quality in Patients Undergoing Endoscopic Sinus Surgeries
Intraoperative bleeding is one of the vital problems for anesthesiologists and surgeons, during endoscopic nasal surgery; where the surgical field is very limited and surrounded by vital structures.
- Conditions
- Nebulization, Intravenous, Surgical Field, Endoscopic Sinus Surgeries
- Trial name
- NCT06777966
- Testing
- nebulized tranexamic acid, intravenous tranexamic acid
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Pilonidal Sinus
Study on Surgical Treatment of Pilonidal Sinus Disease
Comparison of limited excision-primary closure, Limberg, and modified Limberg flap techniques for the surgical treatment of pilonidal sinus disease, each performed by a separate surgeon, in terms of postoperative outcomes and…
- Trial name
- NCT02849197
- Testing
- surgery for pilonidal sinus disease
- Volunteers
- 802 people
- Sponsor
- Bezmialem Vakif University
Wound Healing
Efficacy and Safety of the Investigational Device, SurgiShield Anti-Adhesion Barrier Gel
This clinical trial is intended to evaluate the impact, efficacy, and safety of Chitosan formulated adhesion inhibitor, SurgiShield when used in the process of wound healing after endoscopic sinus surgery.
- Trial name
- NCT01895933
- Testing
- 5ml surgishield
- Where
- 2 sites in South Korea
- Volunteers
- 33 people
- Sponsor
- D.med
Anal Fistula Surgery, High Anal Fistula
IFOC Compared With LIFT in High Anal Fistula
Patients presenting to the outpatient clinic at Kasr Al-Ainy Hospitals with high anal fistula will be assessed according to the inclusion and exclusion criteria.
- Trial name
- NCT07520500
- Testing
- Intra-anal Fistulotomy With Fistula Opening Closure (IFOC), Ligation of the Intersphincteric Fistula Tract (LIFT)
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Cairo University
Pancreatic Cancer, Pancreatic Neoplasms
Monitoring of patIents With Microdialysis Following Pancreaticoduodenectomy
A pancreaticoduodenectomy is performed in patient with pancreatic cancer. The most common and serious complication is leakage between the intestine and the remnant pancreas after this procedure. It occurs in 20-30%.
- Conditions
- Pancreatic Cancer, Pancreatic Neoplasms, Biliary Tract Cancer, Duodenal Cancer
- Trial name
- MINIMUM (NCT03631173)
- Testing
- Surgical og radiological intervention, antibiotics
- Where
- Norway
- Volunteers
- 201 people
- Sponsor
- Oslo University Hospital
Hepatectomy
Postoperative Biliary Fistula Prevention After Hepatectomy
Aim : Effect of external biliary duct stent after hepatectomy on the occurence of postoperative biliary fistula. Methods : French prospective multicenter randomized trial.
- Trial name
- VPI (NCT01469442)
- Testing
- External Biliary duct stent in the bile duct by cystic way
- Where
- 12 sites in France
- Volunteers
- 304 people
- Sponsor
- University Hospital, Toulouse
Head and Neck Cancer, Pain
Acupuncture or Standard Therapy in Treating Pain and Dysfunction in Patients Who Have Undergone Neck Surgery for Head and Neck Cancer
RATIONALE: Acupuncture may help relieve pain and dysfunction caused by cancer surgery. It is not yet known whether acupuncture is more effective than standard therapy in treating pain and dysfunction in patients who have…
- Trial name
- NCT00090337
- Testing
- acupuncture therapy, standard follow-up care
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Meningioma, Tumor, Brain
MiDura-Study (Neuro-Patch in Duraplasty)
The aim of this study is to collect systematically and proactively data regarding the performance of Neuro-Patch, like complications and handling, under daily clinical practice when used as intended by the manufacturer
- Conditions
- Meningioma, Tumor, Brain, Chiari Malformation, Vascular Malformation
- Trial name
- MiDura (NCT04189172)
- Where
- 4 sites in France, Germany
- Volunteers
- 328 people
- Sponsor
- Aesculap AG
Chronic Sinusitis, Nasal Polyps
Steroid-Releasing S8 Sinus Implant for Recurrent Nasal Polyps
The RESOLVE Study is a randomized controlled trial with the S8 Sinus Implant in 100 chronic sinusitis patients with recurrent nasal polyps.
- Trial name
- RESOLVE (NCT01732536)
- Testing
- S8 Sinus Implant, Mometasone furoate nasal spray
- Where
- 19 sites in United States
- Volunteers
- 100 people
- Sponsor
- Intersect ENT
Kegel Exercises
Effect of Anal Lift Exercise on Rehabilitation After Anal Fistula Surgery
This prospective randomized controlled study aims to include patients who have undergone anal fistula surgery, to observe the impact of early postoperative pelvic floor muscle training combined with dietary intervention on…
- Trial name
- NCT07250711
- Testing
- Kegel exercises
- Where
- China
- Volunteers
- 124 people
- Sponsor
- The Affiliated Hospital of Putian University
SILENT SINUS SYNDROME
SILENT SINUS SYNDROME (First Case Report, Saudi Arabia With Recommendation)
Silent sinus syndrome is a rare disorder that presents a diagnostic challenge, most of the patients with this syndrome present with ophthalmological complaints without any nasal sinus symptoms, and it has a painless course and…
- Trial name
- NCT04388345
- Where
- Saudi Arabia
- Volunteers
- 1 people
- Sponsor
- King Saud University
Dental Implant, Sinus Floor Augmentation
Comparing Two Surgical Techniques for Building up the Bone Where a Dental Implant is to be Placed
The goal of this observational study is to compare two techniques routinely used to increase bone volume in the jaw prior to placing a dental implant, called osseocondensation and osseodensification.
- Trial name
- NCT06871657
- Testing
- Sinus lift using osseodensification technique, Sinus lift using the osseocondensation technique
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Ohio State University
Chronic Rhinosinusitis (CRS)
Effectiveness of Penthrox vs Placebo in Sinus Procedures, a Clinical Trial
The goal of this randomized controlled trial is to evaluate the effectiveness of inhaled methoxyflurane (Penthrox) as an analgesic for patients undergoing minor rhinology and sinus procedures, specifically comparing it to a…
- Trial name
- NCT06750302
- Testing
- Methoxyflurane - Penthrox
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- St. Paul's Hospital, Canada
FESS Operation
Intratracheal Dexmedetomidine Versus Lidocaine for Smooth Tracheal Extubation
compare the efficacy of intratracheal dexmedetomidine versus intratracheal lidocaine in achieving smooth tracheal extubation in patients undergoing Functional Endoscopic Sinus surgery and reconstructive nasal surgeries under…
- Trial name
- NCT07504497
- Testing
- dexmedetomidine Lidocaine Saline
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Younes Ahmed Younes
Esophageal Atresia With Tracheo-esophageal Fistula, Esophageal Atresia
Balloon Inflation Time for Esophageal Strictures (BITES): A Randomized Multi-Center Study
Esophageal atresia (EA) is one of the most common gastrointestinal congenital anomalies that affects 1 in 2500 to 1 in 4000 live births.
- Conditions
- Esophageal Atresia With Tracheo-esophageal Fistula, Esophageal Atresia, Esophageal Strictures
- Trial name
- BITES (NCT07100379)
- Testing
- Endoscopic Balloon Dilation
- Where
- 2 sites in United States
- Volunteers
- 128 people
- Sponsor
- Boston Children's Hospital
Dexmedetomidine, Functional Endoscopic Sinus
Intranasal Dexmedetomidine Versus Intravenous Dexmedetomidine for Improving Quality of Endoscopic Sinus Surgery
compare intranasal dexmedetomidine versus intravenous dexmedetomidine for improving quality of the operative field in Functional endoscopic sinus surgery
- Trial name
- NCT06081933
- Testing
- intranasal dexmedetomidine, intravenous dexmedetomidine
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Kafrelsheikh University
Adult Solid Tumor, Breast Cancer
Docetaxel and St. John's Wort in Treating Patients With Solid Tumors That Cannot Be Removed By Surgery
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. St. John's wort may interfere with the effectiveness of chemotherapy.
- Conditions
- Adult Solid Tumor, Breast Cancer, Head and Neck Cancer, Kidney and Urinary Cancer
- Trial name
- NCT00041171
- Testing
- Hypericum perforatum, docetaxel
- Sponsor
- Alliance for Clinical Trials in Oncology
Lidocaine, Dexmedetomidine
Lidocaine and Dexmedetomidine Infusions for Intraoperative Bleeding in Functional Endoscopic Sinus Surgery
This work aims to compare lidocaine and dexmedetomidine infusions for intraoperative bleeding in patients undergoing functional endoscopic sinus surgery.
- Conditions
- Lidocaine, Dexmedetomidine, Infusion, Intraoperative Bleeding
- Trial name
- NCT06848764
- Testing
- Lidocaine, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Pilonidal Sinus
Sacrococcygeal Local Anesthesia With Different Doses of Clonidine for Pilonidal Sinus Surgery
Sacrococcygeal local anesthesia was shown to reduce the time spent in the operating room as well as in the recovery room. In addition, decreased hospital stay and postoperative analgesic consumption.
- Trial name
- NCT02539693
- Testing
- Clonidine 75 µg/mL in sacrococcygeal block, Clonidine 150 µg/mL in sacrococcygeal block, Lidocaine
- Where
- Lebanon
- Volunteers
- 60 people
- Sponsor
- Makassed General Hospital
Perilymphatic Fistulas
Imaging Perilymphatic Fistulas After Barotrauma
Our objective is to validate the CT / MRI combination of non-injected rock for the rapid positive diagnosis of perilymphatic fistulas.
- Trial name
- NCT03543293
- Where
- France
- Volunteers
- 101 people
- Sponsor
- University Hospital, Strasbourg, France