Clinical trials: Short-Sighted
Myopia
Essilor® Stellest® Lenses Multicentre European Study (SLOMES)
The goal of this post-market clinical follow up Study is to demonstrate the efficacy, safety, acceptability, and quality of life implications of Essilor® Stellest® spectacle lenses in slowing myopia progression in European…
- Trial name
- SLOMES (NCT06263946)
- Testing
- Essilor® Stellest® spectacle lenses
- Where
- 3 sites in France, Ireland and 1 more
- Volunteers
- 150 people
- Sponsor
- Essilor International
Myopia
Assessment of Measurement Variability Across Automated Biometry Devices
This is a non-interventional prospective, comparative study of white-to-white, corneal thickness, and anterior chamber depth measurements as taken on the Orbscan II compared to the IOL Master 700 (Zeiss), IOL Master 500 (Zeiss)…
- Trial name
- NCT06045325
- Testing
- Orbscan II, IOL Master 700, IOL Master 500
- Where
- United States
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Berkeley Eye Center
Focus on Axial Length
The Effect of 0.01% Atropine Eye Drops on Axial Length and Refraction in Myopic Children Compared to a Control Group
In this study, atropine 0.01% eye drops will be given to myopic children once at night daily for 6 months as compared to a control group to see the effect on axial length and refraction
- Trial name
- NCT07456488
- Testing
- Atropine 0.01% eye drops
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Liaquat National Hospital & Medical College
Cataract, High Myopia
Evaluation of Cataract Surgery Outcome
The purpose of this study is to evaluate the visual outcome of the cataract surgery, including best uncorrected and corrected visual acuity, spherical equivalent, wavefront aberration and other measurements.
- Trial name
- NCT02182921
- Where
- China
- Volunteers
- 20,000 people
- Sponsor
- Evidence Based Cataract Study Group
Myopia, Cataract
Influence of Posterior Vitreous Detachment on Retinal Detachment After Lens Surgery in Myopic Eyes
Phacoemulsification with implantation of posterior chamber lenses represents the gold standard of care for patients needing lens surgery, but there is an increased risk of developing pseudophakic retinal detachment after surgery.
- Conditions
- Myopia, Cataract, Pseudophakic Retinal Detachment, Refractive Lens Exchange
- Trial name
- MYOPRED (NCT03152747)
- Where
- Austria
- Volunteers
- 609 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Pseudoexfoliation Syndrome in Cataract Myopic Eyes
Pseudoexfoliation Syndrome in Myopes
A retrospective study of 5753 eyes of cataract surgery patients was conducted at our Clinic. Ocular optical components measured by optical low coherence reflectometry biometer LENSTAR LS 900® of the cataract myopic eyes with…
- Trial name
- NCT01637740
- Volunteers
- 5,753 people
- Sponsor
- General Hospital Sveti Duh
High Myopia, Pathologic Myopia
Shanghai Child and Adolescent Large-scale Eye Study -High Myopia Registration
1.1 Research objectives A．To observe the fundus changes in the posterior pole (morphology, thickness, asymmetry, blood flow density, etc) with the myopia progression.
- Trial name
- SCALE-HM (NCT03666052)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Presbyopia, Near Vision
Phase 3 Safety Study of LNZ100 and LNZ101 for the Treatment of Presbyopia Subjects
Safety Study of the Long-Term Safety of LNZ100 \& LNZ101 in Presbyopic Subjects
- Conditions
- Presbyopia, Near Vision, Refractive Error, Eye Diseases
- Trial name
- NCT05753189
- Testing
- Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle
- Where
- 40 sites in United States
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- LENZ Therapeutics, Inc
Myopia, Refractive Error
Comparative Study of Cycloplegic Refraction and Subjective Refraction With Fogging in School Age Children
A thorough ophthalmic examination of a child must include a refraction and this is often done with cycloplegia. In our study, we aim to determine at which age group a non-cycloplegic refraction technique closely correlates with a…
- Trial name
- NCT00347347
- Where
- Singapore
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Myopia, Hyperopia
Clinical Evaluation of Two Frequent Replacement Soft Spherical Contact Lenses
This was a single-blind (participant masked), interventional, prospective, direct refit, bilateral wear short-term fitting study.
- Trial name
- NCT05656885
- Testing
- Lens A, Lens B
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Binocular Peripheral Myopic Defocus Using a Clinical Prototype Device
Kubota Vision Inc. has developed a spectacle-like prototype device which is designed to be used as a light-based therapy to reduce myopia progression.
- Trial name
- NCT05425108
- Testing
- Binocular CP1
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Kubota Vision Inc.
Myopia, Progressive
Differences and Wearing Safety and Comfort of New Defocus Incorporated Multiple Segments Spectacle Lenses
To evaluate the differences in controlling the progression of myopia in adolescents and the safety and comfort of wearing different types of defocus incorporated multiple segments spectacle lenses, to explore the feasibility of…
- Trial name
- NCT06221592
- Testing
- defocus spectacle lenses
- Where
- China
- Volunteers
- 252 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
AI-Stratified Myopia Control for Children in Remote Areas
This cluster-randomized controlled trial aims to evaluate the effectiveness and cost-effectiveness of an artificial intelligence-based, risk-stratified, tiered intervention model for childhood myopia prevention and control in…
- Trial name
- NCT07825428
- Testing
- Routine Screening and Referral, AI-Guided Tiered Management
- Where
- 3 sites in China
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Evaluation of Stenfilcon A Versus Etafilcon A
Evaluation of two contact lenses
- Trial name
- NCT01809834
- Testing
- Etafilcon A, Stenfilcon A
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- CooperVision, Inc.
Refractive Error - Myopia Bilateral
Clinical Performance of 59% Hioxifilcon A vs. Marketed Hydrogel Contact Lenses in Habitual Hydrogel Wearers
The study will compare the short-term clinical performance and wearer and practitioner acceptability of a new-to-market spherical daily disposable (DD) hydrogel soft contact lens to a currently marketed spherical DD hydrogel soft…
- Trial name
- NCT04986644
- Testing
- Hioxifilcon A standard hydrogel contact lens with Hyaluronic Acid (HA)
- Where
- 2 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Vision Service Plan
Myopia
Clinical Study of Approved Contact Lenses
Evaluation of Johnson \& Johnson Acuvue Vita (senofilcon C) soft contact lenses to the Bausch + Lomb Ultra (samfilcon A) soft contact lenses
- Trial name
- NCT03351101
- Testing
- Senofilcon C, Samfilcon A
- Where
- 11 sites in United States
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Post-market Follow Up Study on Paragon CRT® 100 (Paflufocon D)
The main objective of this post market clinical study is to evaluate the effectiveness and safety of the Paragon CRT®100 Contact Lens.
- Trial name
- NCT04187599
- Testing
- Paragon CRT®100 Contact Lens
- Where
- 4 sites in China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- CooperVision International Limited (CVIL)
Myopia
To Evaluate the Effectiveness of New Specially Designed Fitlens Soft Lens.
Myopia is a common disorder, affecting approximately one-third of the US population and over 90% of the population in some East Asian countries.
- Trial name
- NCT05433792
- Testing
- Myolens CN (Central-Near) soft contact lens, MiSight® soft contact lens
- Where
- Israel
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Fitlens Ltd.
Myopia
Change in Choroidal Thickness of Myopic Eyes With a Myopia Control Contact Lens
In this study, the direct effect of the MiSight contact lens (Cooper Vision), a daily disposable contact lens recently approved in Germany for the treatment of myopia, will be investigated.
- Trial name
- NCT06636019
- Testing
- Myopia control contact lens
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital Augsburg
Myopia
Safety and Efficacy of Defocus Distributed Multi-point Lens in Myopia Control
Evaluate the safety and effectiveness of experimental group by comparing with the control group
- Trial name
- NCT05340699
- Testing
- Defocus Distributed Multi-point lens, Single vision lens
- Where
- China
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital