Clinical trials: Shock, Cardiogenic
Acute Respiratory Distress Syndrome (ARDS), Cardiogenic Shock
Cerebral Autoregulation in Pediatric ECMO (ECMOX 2)
Children supported by Extra-Corporeal Membrane Oxygenation (ECMO) present a high risk of neurological complications and cerebral autoregulation (CA) impairment may be a risk factor.
- Conditions
- Acute Respiratory Distress Syndrome (ARDS), Cardiogenic Shock, Cardiac Arrest
- Trial name
- ECMO-ECMOX2 (NCT04548739)
- Where
- 4 sites in France, Italy
- Volunteers
- 132 people
- Sponsor
- Nantes University Hospital
Myocardial Infarction, Acute, Cardiogenic Shock
IABP In AMI Patients With SCAI-B Study
Acute myocardial infarction (AMI) is the most common cause of cardiogenic shock (CS), and CS is the most common cause of death in patients with AMI.
- Trial name
- NCT04989777
- Testing
- IABP (Intra-aortic balloon pump ) implantation
- Where
- China
- Volunteers
- 512 people
- Sponsor
- Renmin Hospital of Wuhan University
Cardiogenic Shock, Acute Coronary Syndrome
LATIN SHOCK: Latin American Registry of Cardiogenic Shock in the Context of Acute Coronary Syndrome
This is a Registry of the characteristics and clinical evolution of patients admitted for acute coronary syndromes (with or without st segment elevation) who present with cardiogenic shock or develop it during the hospitalization…
- Trial name
- LATIN-SHOCK (NCT05246683)
- Testing
- observational
- Where
- Argentina
- Volunteers
- 700 people
- Sponsor
- Sociedad Argentina de Cardiología
Cardiogenic Shock
Cardiogenic Shock Intravascular Cooling Trial
The purpose of the study is to compare patients with cardiogenic shock who receive standard therapy plus therapeutic hypothermia (TH) to patients with cardiogenic shock who receive standard medical therapy alone in order to…
- Trial name
- CHILL-SHOCK (NCT03141255)
- Testing
- IVTM™ System, Quattro® Catheter
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Chicago
Shock
Dopamine and Norepinephrine in Shock Patients
The purpose of this study is to compare the efficacy of dopamine and norepinephrine, two commonly used vasopressor agents, in the treatment of shock.
- Trial name
- NCT00314704
- Testing
- dopamine versus norepinephrine
- Where
- 8 sites in Austria, Belgium and 1 more
- Volunteers
- 1,679 people
- Sponsor
- Sepsis Occurrence in Acutely Ill Patients
Cardiogenic Shock, Frailty
Prognostic Impact of Frailty in Cardiogenic Shock
The goal of this observational study is to show prognostic impact of frailty in cardiogenic shock according to age. The main questions it aims to answer are: Can frailty successfully predict outcomes in cardiogenic shock? Whether…
- Conditions
- Cardiogenic Shock, Frailty, Age
- Trial name
- NCT07260084
- Volunteers
- 207,419 people
- Sponsor
- Samsung Medical Center
Cardiovascular Shock, Respiratory Failure
Analysis of Endotoxin Activity in Patients With ECMO
Extra-corporeal membrane oxygenation (ECMO) can temporarily help patients gain time to wait for cardiopulmonary recovery or further treatment in patients with cardiopulmonary failure.
- Trial name
- NCT03978728
- Testing
- Extra-corporeal membrane oxygenation
- Where
- Taiwan
- Volunteers
- 55 people
- Sponsor
- National Taiwan University Hospital
Cardiogenic Shock, Extracorporeal Membrane Oxygenation Support
Early LA Venting During Venoaterial ECMO Support
The EVOLVE-ECMO(Early Left Atrial Venting Versus Conventional Treatment For Left VEntricular Decompression During Venoarterial ExtraCorporeal Membrane Oxygenation Support) study is a randomized controlled trial to evaluate the…
- Conditions
- Cardiogenic Shock, Extracorporeal Membrane Oxygenation Support, Refractory Pulmonary Edema
- Trial name
- NCT03740711
- Testing
- Left atrial venting
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Asan Medical Center
Cardiogenic Shock
IMPELLA, Complications and Tolerance
Myocardial infarction complicated by cardiogenic shock (AMICS) is associated with high morbidity and mortality, and devices like Impella® CP and Impella 5.0-5.5 are often used for hemodynamic support, either alone or combined…
- Trial name
- IMPACT (NCT06644963)
- Testing
- Impella (5, 5.5 or CP)
- Where
- France
- Volunteers
- 800 people
- Sponsor
- University Hospital, Montpellier
Extracorporeal Membrane Oxygenation, Nitric Oxide
Nitric Oxide in Venoarterial Extracorporeal Membrane Oxygenation (VA ECMO)
This pilot study is designed to investigate the effect of inhaled nitric oxide on cardiac, pulmonary artery, and systemic hemodynamics at various time points during venoarterial extracorporeal membrane oxygenation (VA-ECMO)…
- Conditions
- Extracorporeal Membrane Oxygenation, Nitric Oxide, Shock, Cardiogenic
- Trial name
- NOVICE (NCT04224103)
- Testing
- Inhaled nitric oxide
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Filio Billia
Myocardial Infarction, Cardiogenic Shock
Aortic Balloon Counterpulastion in Myocardial Infarction Related Shock
The role of intra aortic balloon counterpulsation in patients experiencing acute myocardial infarction with shock is not established. We hypothesised that use of such a device would lead to improved outcomes in these patients.
- Trial name
- IABPSHOCK (NCT00469248)
- Testing
- Intra-aortic balloon pump counterpulsation
- Where
- Germany
- Volunteers
- 45 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Cardiogenic Shock
The Current Status and Clinical Outcomes of Patients With Cardiogenic Shock II
The investigation of patient characteristics and prognostic factors of the patients presented with cardiogenic shock (CS) will guide us to identify the better management strategy for these critically ill patients.
- Trial name
- RESCUE II (NCT04143893)
- Testing
- Mechanical circulatory support, Optimal medical treatment
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Samsung Medical Center
Acute Coronary Syndrome, Recurrent Myocardial Infarction
Primary Prevention With Statin and Incidence of Recurrent MI and Cardiogenic Shock in Post-ACS Patients
This study aims to evaluate the effect of statin for primary prevention, towards lowering the incidence of recurrent myocardial infarction, cardiogenic shock and mortality in ACS patients.
- Conditions
- Acute Coronary Syndrome, Recurrent Myocardial Infarction, Cardiogenic Shock
- Trial name
- NCT03596944
- Testing
- Statin
- Where
- Indonesia
- Volunteers
- 145 people
- Sponsor
- Tarumanagara University
Cardiogenic Shock
Prognostic Value of the Rockwood Clinical Frailty Score in Cardiogenic Shock
Cardiogenic shock (CS) is characterized by tissue hypoperfusion resulting from cardiac dysfunction, without hypovolemia, where the ventricular pump is unable to generate adequate blood flow to meet the metabolic needs of the…
- Trial name
- FrailShock (NCT06692855)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
Cardiogenic Shock
Management of Acute Cardiogenic Shock at the New Brunswick Heart Centre
In Atlantic Canada, acute myocardial infarction occurs at a rate of 2.9 % of the population and is the most common cause of cardiogenic shock (CS).
- Trial name
- Team-Shock (NCT05414643)
- Testing
- Standard care
- Where
- Canada
- Volunteers
- 1,416 people
- Sponsor
- New Brunswick Heart Centre
Cardiogenic Shock
Clinical Effects of Intra-aortic Balloon Support in Early Acute Coronary Syndrome and Non-Acute Coronary Syndrome Related Cardiogenic Shock
The goal of this randomized controlled trial is to appraise the impact of intra-aortic balloon pump (IABP) in the treatment of early stages of cardiogenic shock, irrespective of etiology.
- Trial name
- IABP ON-TIME (NCT06414187)
- Testing
- Intra-Aortic Balloon Pump
- Where
- Netherlands
- Volunteers
- 400 people
- Sponsor
- Erasmus Medical Center
Low Cardiac Output Syndrome, Cardiogenic Shock
Milrinone Versus Dobutamine in Critically Ill Patients
The investigators are interested in determining if there is a meaningful difference between two of the most commonly used medications used to improve the pumping function of the heart among critically ill patients admitted to the…
- Conditions
- Low Cardiac Output Syndrome, Cardiogenic Shock, Acute Coronary Syndrome, Pulmonary Edema
- Trial name
- NCT03207165
- Testing
- Milrinone, Dobutamine
- Where
- Canada
- Volunteers
- 192 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Cardiac Arrest, Cardiopulmonary Arrest
ECMELLA vs. ECMO on 30-day Mortality
This international, multicenter cohort study aims to investigate outcomes after treatment with extracorporeal cardiopulmonary resuscitation (eCPR) during cardiac arrest.
- Conditions
- Cardiac Arrest, Cardiopulmonary Arrest, Extracorporeal Membrane Oxygenation Complication, Cardiogenic Shock
- Trial name
- NCT05175898
- Testing
- VA-ECMO, ECMELLA
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Charite University, Berlin, Germany
Cardiogenic Shock
Polish Nationwide Registry of Diagnostics, Treatment and Outcome in Patients With Cardiogenic Shock
The registry objective is to get information on current epidemiology, diagnostics, treatment and outcome in patients with cardiogenic shock in Poland.
- Trial name
- CaS-POL (NCT06697093)
- Where
- 2 sites in Poland
- Volunteers
- 500 people
- Sponsor
- Wroclaw Medical University
Heart Failure With Reduced Ejection Fraction, Cardiogenic Shock
Pulmonary Artery Catheterization and Carvedilol Early Initiation in Cardiogenic SHOCK Due to HFrEF
This study aims to compare the impact of hemodynamic monitoring using pulmonary artery catheter (PAC) on survival and inotropic agent reduction in patients with cardiogenic shock caused by heart failure with reduced ejection…
- Trial name
- PACE-SHOCK (NCT06078436)
- Testing
- Pulmonary artery catheter
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Min-Seok Kim