Clinical trials: Sexual Health
Breast Cancer, Vaginal Dryness
Breast Cancer, Aromatase Inhibitor Therapy, and Sexual Functioning: The Effects of Vaginal Testosterone Therapy
It is well documented that women who have breast cancer may experience a decrease in quality of life and sexual functioning due to side effects from adjuvant endocrine therapy, typically aromatase inhibitors (AIs).
- Conditions
- Breast Cancer, Vaginal Dryness, Dyspareunia, Sexual Health Quality of Life
- Trial name
- NCT01697345
- Testing
- Testosterone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Creighton University
HIV, Adolescent Behavior
Gender-Specific Combination HIV Prevention for Youth in High Burden Settings (MP3-Youth)
MP3 Youth is a pilot study to evaluate the feasibility and acceptability of a gender-specific combination HIV prevention package for youth (aged 15-24) in high burden settings.
- Conditions
- HIV, Adolescent Behavior, Gender
- Trial name
- MP3-Youth (NCT01571128)
- Testing
- Male-Specific Intervention Package, Female-Specific Intervention Package, Pre-Exposure Prophylaxis (Females)
- Where
- 3 sites in United States, Kenya
- Volunteers
- 1,215 people, healthy volunteers welcome
- Sponsor
- New York University
HIV, AIDS
Motivating HIV+ Women: Risk Reduction and ART Adherence
The purpose of this study is to determine if a group motivational interviewing based intervention will increase adherence to antiretroviral medications and use of risk reduction behaviors.
- Trial name
- KHARMA (NCT00253045)
- Testing
- Motivational groups
- Where
- United States
- Volunteers
- 207 people
- Sponsor
- Emory University
Colorectal Cancer (Diagnosis), Anal Cancer
Mind-Body Sexual Well-Being Program for Female GI Cancer Survivors
This record describes two distinct study phases: 1) A small open pilot trial including up to 10 participants, intended to generate descriptive feedback on regarding perceived benefits and areas for improvement for a group-based…
- Conditions
- Colorectal Cancer (Diagnosis), Anal Cancer, Sexual Dysfunction Female
- Trial name
- NCT07795801
- Testing
- Mind-Body Group Intervention, Enhanced Usual Care Control (EUCC)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Human Immunodeficiency Virus, Human Immunodeficiency Virus Transmission
The OPENS Trial: Offering Women PrEP (Aim 2)
To address the significant barriers to pre-exposure prophylaxis (PrEP) implementation for cisgender women and address racial inequities in HIV prevention in the United States (US), a novel approach that accounts for multilevel…
- Conditions
- Human Immunodeficiency Virus, Human Immunodeficiency Virus Transmission, Sexually Transmitted Diseases
- Trial name
- NCT05619497
- Testing
- Clinic-wide Trainings, Clinic-wide Trainings and HIV Prevention Decision Support Tool (DST), Standard Care with the HIV Prevention Decision Support Tool (DST)
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Well Being, Drug Addiction
Evaluation of Effectiveness of the LifeSkills Training - Lombardia - Primary Shool Program ( Val3P-LST )
Life Skills Training is a school-based prevention program aiming at promoting wellbeing and at preventig use of substances. It has a version for middle school and another for primary school students.
- Conditions
- Well Being, Drug Addiction, Tobacco Use, Alcohol Abuse
- Trial name
- Val3P-LST (NCT07858513)
- Testing
- life skills primary prevention
- Where
- Italy
- Volunteers
- 3,927 people, healthy volunteers welcome
- Sponsor
- Agenzia di Tutela della Salute della Città Metropolitana di Milano
HIV Infections, Pregnancy Related
Reaching 90 90 90 in Adolescents in Zambia: Using All Our SKILLZ
"SKILLZ," is a mixed methods evaluation of the Grassroots Soccer (GRS) SKILLZ Package based in Lusaka, Zambia. The package is made up of three football-based programs: (1) SKILLZ-Girl - implemented in schools as part of a 10-week…
- Conditions
- HIV Infections, Pregnancy Related, STI, Mental Health Wellness 1
- Trial name
- SKILLZ (NCT04429061)
- Testing
- SKILLZ-Girl curriculum
- Where
- Zambia
- Volunteers
- 2,153 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Sexual Dysfunction, Rectal Surgery
Prevalence of Sexual Dysfunction After Rectal Surgery and Patient Satisfaction of Preoperative Discussions
Sexual dysfunction after rectal surgery varies widely in the literature. Prevalence of sexual dysfunction before surgery and desire of patient to treat this condition is also not well established.
- Conditions
- Sexual Dysfunction, Rectal Surgery, Patient Satisfaction
- Trial name
- NCT05010486
- Testing
- rectal surgery
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Contraception
Evaluation of a Peer Education Program to Promote Family Planning Among Female Sex Workers in Kenya
-Purpose: To develop and evaluate an intervention designed to improve consistent contraceptive use and dual method use in particular, among female sex workers (FSWs) in Rift Valley Province in Kenya.
- Trial name
- NCT01957813
- Testing
- Lifestyle Counseling, Standard Health Services
- Where
- 2 sites in Kenya
- Volunteers
- 719 people, healthy volunteers welcome
- Sponsor
- FHI 360
Human Immunodeficiency Virus, Substance Use
Harm Reduction in HIV Primary Care for PLWH Who Use Drugs
People living with HIV (PLWH) who use drugs experience significant health disparities including lower rates of retention in HIV care and higher rates of unsuppressed viral load, resulting in secondary infections and increased…
- Conditions
- Human Immunodeficiency Virus, Substance Use, Stigma, Social
- Trial name
- NCT05404750
- Testing
- Harm Reduction
- Where
- 3 sites in United States
- Volunteers
- 641 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Erectile Dysfunction
Psychotherapy and Pharmacotherapy in the Treatment of Erectile Dysfunction: A Pilot Study
The study involved the administration of pharmacotherapy and cognitive behavior psychotherapy to individuals suffering from erectile dysfunction. The study was randomized controlled trial with two arms involving a control group.
- Trial name
- NCT04179747
- Testing
- Cognitive Behavioral Psychotherapy, Sildenafil Citrate 50Mg Tab
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- International Islamic University, Islamabad
Vulnerable Population
Evaluation of the Acceptability and Impact of a Sexual Health Screening and Prevention Program for Vulnerable Women
Globally, women accounted for more than half of people living with HIV (53%) in 2022. In France, 54% of new infections were heterosexual in 2022, 71% of whom were born abroad, mainly in sub-Saharan Africa (74%).
- Trial name
- PrEVE (NCT06996938)
- Testing
- Rapid diagnostic orientation tests (TROD) HIV, Hepatitis, syphilis
- Where
- 2 sites in France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida
HIV/AIDS, Medication Adherence
An Integrated Intervention Using a Pill Ingestible Sensor System
This study integrates technology-based adherence measures with alerts for social and behavioral determinants of health (SBDOH) to improve HIV treatment outcomes.
- Conditions
- HIV/AIDS, Medication Adherence, Social Determinants of Health (SDOH)
- Trial name
- Sensor-SBDOH (NCT06480578)
- Testing
- ISS-SBDOH arm
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of California, Los Angeles
Alcoholic Intoxication
Alcohol Myopia, Objectification, and Sexual Assault
The present project integrates previous research on factors associated with alcohol-involved sexual assault, with research on how intoxication alters attention and social perceptions in ways that increase the risk of sexual…
- Trial name
- NCT03956238
- Testing
- Alcohol intoxication, Objectification
- Where
- United States
- Volunteers
- 359 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Health Care Quality, Access, and Evaluation, Delivery of Health Care
Improving HIV Screening With Nurse-Based Rapid Testing/Streamlined Counseling
Background: HIV testing is cost-effective in unselected general medical populations, yet testing rates among those at-risk remain low, even among those with regular primary care.
- Conditions
- Health Care Quality, Access, and Evaluation, Delivery of Health Care, Immune System Diseases, HIV Infections
- Trial name
- NCT00119548
- Testing
- Rates of HIV testing and receipt of results, Sexual risk reduction; HIV knowledge improvement
- Where
- United States
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
HIV Infections, Viral Load
Smart Linkage-to-HIV Care Via a Smartphone App
This randomized controlled trial evaluates the provision of individual patient laboratory results to newly diagnosed HIV positive smartphone users through a secure application (app) as a method to get them linked to and retained…
- Conditions
- HIV Infections, Viral Load, Patient Compliance, Antiretroviral Therapy
- Trial name
- SmartLtC (NCT02756949)
- Testing
- Smartphone application, Smartphone
- Where
- South Africa
- Volunteers
- 353 people
- Sponsor
- World Bank
HIV Infections
Improving Identification of Mental Health/Substance Use Disorders in HIV Primary Care: Pilot Clinical Response
This research is a feasibility pilot of an intervention to respond to positive screening tests for mental health(MH) and substance use (SU) captured through the Patient Reported Outcomes questionnaires (PROs).
- Trial name
- PROACT (NCT03067948)
- Testing
- Patient Designated Positive Screen Shared with Provider
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Johns Hopkins University
HIV (Human Immunodeficiency Virus), AIDS (Acquired Immunodeficiency Syndrome)
Video Information Provider for HIV-Associated Non-AIDS (VIP-HANA) Symptoms
The purpose of this study is to use technology to improve symptom status and ultimately improve patient centered outcomes in people living with HIV/AIDS (PLWHA).
- Trial name
- VIP-HANA (NCT03182738)
- Testing
- VIP app without HIV-related symptom strategies., VIP app that delivers HIV-related symptom strategies.
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Columbia University
Sexual Compulsive Behavior Disorder, Cybersex Addiction
Effectiveness Study of Individual Online Treatment for Cybersex Addiction/Online Sexual Compulsive Behavior Disorder
Cybersex addiction, understood as a subtype of Internet addiction or a manifestation of Compulsive Sexual Behavior Disorder, is a growing phenomenon.
- Conditions
- Sexual Compulsive Behavior Disorder, Cybersex Addiction, Online Compulsive Sexual Behavior
- Trial name
- ADISEX (NCT06951555)
- Testing
- Online Individual Cognitive-Behavioral Therapy (CBT)
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Universitat Jaume I
HIV Infection
Antiretroviral Speed Access Program
Migrant populations represent an increasing proportion of newly referred people living with HIV in Canada, particularly in Quebec.
- Trial name
- ASAP (NCT04897243)
- Testing
- Biktarvy, Patient Experience
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- Dr. Bertrand Lebouche