Clinical trials: Sevoflurane
Coughing on Induction, Vapors; Inhalation
Two Different Preparations of Sevoflurane in Induction
In our study we aim to study the effects of two preparations of Sevoflurane in vital capacity rapid inhalation induction.
- Trial name
- NCT01792063
- Testing
- Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Istanbul University
Erection; Incomplete
Effect of Propofol vs. Sevoflurane on Erections During Narcosis In Transurethral Surgery
Penile erection is an unwanted event in transurethral (through the urethra) surgeries, which may be associated with adverse outcomes such as impaired access, prolonged operation time, the need to abort the operation, or the…
- Trial name
- PENIS (NCT06378645)
- Testing
- General Anesthesia: Propofol, General Anesthesia: Sevoflurane
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Etienne Xavier Keller
Post-Operative Pain
Pregabalin Versus Celecoxib on Sevoflurane and Analgesic Consumption in Spine Fixation Surgery
The anti-epileptic drugs such as gabapentin and other non-steroidal anti-inflammatory drugs (NSAID) such as celecoxib were used as a part of multimodal analgesia to control such pain.
- Trial name
- NCT04342065
- Testing
- Celecoxib capsules, Pregabalin 150mg
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- South Egypt Cancer Institute
Cognitive Dysfunction, Auditory Dysfunction, Central
Effect of Propfol Versus Sevoflurane on Auditory and Cognitive Function
Perioperative hearing loss is a rarely reported phenomenon. However, it occurs more frequently than most anaesthesiologists suspect.
- Trial name
- NCT04874545
- Testing
- Propofol
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Beni-Suef University
Delirium, Postoperative Cognitive Dysfunction
Impact of Desflurane and Sevoflurane on Postoperative Delirium in Elderly Patients
Advanced age is a consistent risk factor for the incidence of postoperative cognitive decline, which is associated with longer hospital stays, decreased quality of life, and increased mortality.
- Trial name
- NCT06176144
- Testing
- Desflurane, Sevoflurane
- Where
- China
- Volunteers
- 890 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Postoperative Delirium, Postoperative Recovery in Elderly Patients
Recovery After Upper Extrimety Surgery
The goal of this randomized clinical trial is to determine whether Bispectral Index (BIS)-guided general anesthesia improves postoperative cognitive recovery and overall quality of recovery in adults undergoing elective hand or…
- Conditions
- Postoperative Delirium, Postoperative Recovery in Elderly Patients, Postoperative Cognitive Dysfunction (POCD)
- Trial name
- Recovery (NCT07714928)
- Testing
- BIS-Guided General Anesthesia, Clinically Guided General Anesthesia
- Where
- Sweden
- Volunteers
- 112 people
- Sponsor
- Region Örebro County
Anesthesia; Functional, Anesthesia Awareness
The Effect of Minimal Flow Sevoflurane Anesthesia
Our aim is to investigate the effect of minimal flow anesthesia with sevoflurane on hemodynamics and arterial blood gas parameters in laparoscopic cholecystectomy operations.
- Trial name
- NCT04813952
- Testing
- Sevoflurane inhalant product
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Ear Deformities, Acquired
The Effect of General Anesthesia on the Middle Ear Pressure
The investigators aimed to examine the effect of sevoflurane and desflurane, agents used in patients who do not have any ear pathology and undergo surgery under general anesthesia, on the MEP.
- Trial name
- NCT03100604
- Testing
- desflurane,, Sevoflurane
- Volunteers
- 50 people
- Sponsor
- Trakya University
Anesthesia, Stress
The Effect of Intraoperative Music Listening on Sevoflurane Consumption and Recovery Parameters
The perioperative period can be a significant source of psychological burden, anxiety and fear for patients Both pharmacological and non-pharmacological methods have been proposed in order to alleviate perioperative stress Music…
- Conditions
- Anesthesia, Stress, Music, Auditory Perception
- Trial name
- NCT02220452
- Testing
- music listening during anesthesia, absence of music listening during anesthesia
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Aretaieion University Hospital
Magnesium Sulfate, Remifentanil
Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension
This prospective, randomized controlled trial investigates the effect of four different anesthetic maintenance techniques on surgical field conditions, hemodynamic stability, and neuroprotection during functional endoscopic sinus…
- Conditions
- Magnesium Sulfate, Remifentanil, S 100beta, S100 Beta Protein, Human
- Trial name
- NCT07181564
- Testing
- Propofol / Remifentanil, Ketamine + Magnesium sulfate (drug combination), Sevoflurane and Remifentanil
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- University General Hospital of Patras
Agitation
ED50 of Dexmedetomidine to Prevent Emergence Agitation in Children
There are several recommended doses of dexmedetomidine for prevention of emergence agitation in children. In this study, the investigators examine ED50 in prevention of emergence agitation after tonsillectomy or adenoidectomy in…
- Trial name
- NCT01374737
- Testing
- Dexmedetomidine
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Seoul National University Hospital
RSV Infection in Children Less Than 5 Years of Age, General Anesthesia
The Effect of Sevoflurane on Airway Hyperreactivity During the Perioperative Period.
To investigate the effects of sevoflurane on respiratory parameters and respiratory inflammation in healthy and RSV-infected under general anesthesia and to propose suitable perioperative airway protection measures for children…
- Trial name
- NCT06694675
- Testing
- Sevoflurane (Volatile Anesthetic), propofol
- Where
- 2 sites in China
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- First Hospital of China Medical University
Isoflurane, Sevoflurane
Impact of Isoflurane and Sevoflurane on Oxidative Stress in Patients Undergoing Laparoscopic Cholecystectomy
The primary aim of this work is to assess the impact of exposure to isoflurane or sevoflurane as an inhalation anesthetic on the oxidative stress and inflammatory conditions in patients undergoing elective moderate invasive…
- Conditions
- Isoflurane, Sevoflurane, Oxidative Stress, Laparoscopic Cholecystectomy
- Trial name
- NCT07152912
- Testing
- Isoflurane, Sevoflurane
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Brain Cancer
Sugammadex Given for the Reversal of Rocuronium Induced Neuromuscular Blockade Under Sevoflurane Anesthesia in Infants
The objective of this study is to evaluate the efficacy and safety of sugammadex in reversing profound neuromuscular block induced by rocuronium in infant patients
- Trial name
- NCT02708056
- Testing
- Sugammadex
- Volunteers
- 26 people
- Sponsor
- Baskent University
Cataract, Retina Detachment
Different Hemostasis According to the Anesthetic Agents
We investigated the hemostatic differences according to the main anesthetic agents by analyzing rotational thromboelastometry (ROTEM) under the hypothesis that propofol-based anesthesia would impair postoperative coagulability…
- Conditions
- Cataract, Retina Detachment, Pterygium, Keratitis
- Trial name
- NCT02151305
- Testing
- Propofol, remifentanil, Sevoflurane
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Seoul National University Bundang Hospital
Pediatric Anesthesia, Emergence Delirium, Anesthesia
Impact of EEG-guided Sevofluorane on Opioid Consumption and Quality of Awakening
This prospective, randomized, single-blind, two-arm parallel-group clinical trial evaluates whether EEG-guided sevoflurane titration affects intraoperative opioid consumption and emergence quality in children undergoing painful…
- Conditions
- Pediatric Anesthesia, Emergence Delirium, Anesthesia, Postoperative Pain, Tonsillectomy
- Trial name
- NCT07714785
- Testing
- EEG-guided, Standard
- Where
- Chile
- Volunteers
- 50 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Emergence Agitation, Postoperative Pain
Caudal Versus Intravenous Magnesium Sulfate on Emergence Agitation After Sevoflurane In Children.
Sevoflurane is the agent of choice for induction and maintenance of day care anesthesia in children and has a wide acceptance among pediatric anesthesiologists.
- Trial name
- NCT03846284
- Testing
- Bupivacaine, Magnesium sulfate 50mg, Magnesium sulfate 30 mg
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Mansoura University
Anesthetic Gas Consumption and Cost-Effectiveness
Comparison of Different Ventilator and Vaporizer Technologies to Study Economic and Environmental Implications
The purpose of this study is to test whether or not the use of a low volume ventilator in an anesthesia machine reduces anesthetic costs significantly as compared to other high volume machines.
- Trial name
- NCT04851314
- Testing
- ICU certified ventilator, Non-ICU certified ventilator
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of California, Irvine
Anesthesia; Adverse Effect
Does Sevoflurane Cause Genomic Damage
This study aims to find out if sevoflurane causes any cell damage to patients undergoing general anaesthesia. In case of any damage, the reversibility of the damage is also assessed.
- Trial name
- NCT03109119
- Testing
- Sevoflurane, Propofol
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Jubilee Mission Medical College and Research Institute
Obesity (BMI>30), Postoperative Cognitive Function
Postoperative Cognitive Function After Different Anesthetic Techniques in Obese Patients
Obese patients are at increased risk of postoperative cognitive dysfunction (POCD). The effects of different anesthetic techniques on postoperative cognitive function remain controversial.
- Trial name
- NCT07665645
- Testing
- Sevoflurane (Volatile Anesthetic), propofol, Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Gaziantep City Hospital