Clinical trials: Senior
Hypertension
Knowledge on Preventive Measures of Hypertension
Hypertension among children and adolescents is on the rise in both developed and developing countries. Childhood and adolescent obesity, a key factor for hypertension in this population results largely from unhealthy dietary and…
- Trial name
- NCT04554017
- Testing
- Education/Training
- Where
- Ghana
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Garden City University College
Healthy
Effect of Different Working Conditions on Risk Factors in Dentists Versus Trainers
The aim of the study is to validate the sanitary consequences of dental studies respectively the longtime executed profession. In comparison to this cohort we will also check a collective of subjects with an optimum of physical…
- Trial name
- NCT00521235
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Motion Sickness
Prevention and Treatment of Nausea Associated With Motion Sickness in Senior Subjects
A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of the Safety, Efficacy and Pharmacokinetics of DPI 386 Nasal Gel for the Prevention and Treatment of Nausea Associated with Motion Sickness in Senior Subjects With…
- Trial name
- NCT03988530
- Testing
- Scopolamine
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Repurposed Therapeutics, Inc.
Senior Abuse
The Impact of Social Phone Calls With Isolated Older Adults Receiving Protective Services for Abuse, Neglect and/or Exploitation
The purpose of this study is to see the the impact of social visits, through weekly phones calls, on quality of life outcomes of depression, anxiety, loneliness, isolation and self-rated health for older adults visited by Adult…
- Trial name
- NCT05026762
- Testing
- Treatment
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- The University of Texas Health Science Center, Houston
Foot
Foot Self-care in Older Adults
This pilot study will make a preliminary evaluation of the efficacy of 2 Feet 4 Life, a foot care self-management program, on foot care knowledge, foot care self-efficacy, foot care behaviors, and foot pain in community dwelling…
- Trial name
- NCT03656341
- Testing
- 2 Feet 4 Life
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Human Microbiome, Antibiotic Resistant Infection
Clinical/Microbiological Impact of a Specific Antimicrobial Stewardship Program for Nursing Homes
Background: In nursing homes, excessive and inappropriate use of antimicrobials, adverse events caused by these drugs, and infections by multidrug-resistant bacteria (MDRB) are more frequent than in the general population, posing…
- Conditions
- Human Microbiome, Antibiotic Resistant Infection, Nursing Homes
- Trial name
- PROA-SENIOR (NCT03543605)
- Testing
- PROA Experimental, PROA Control
- Where
- Spain
- Volunteers
- 1,667 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Achilles Tendinopathy (AT)
Change in ATOR Screening Test Scores Over 12 Weeks
Achilles tendinopathy (AT) is one of the most common overuse injuries in runners, with an estimated incidence ranging from 0.6% to 18.5% of all running-related injuries, reaching up to 52% in elite runners.
- Trial name
- ATOR (NCT07497217)
- Testing
- Alfredson Exercise Program + Health Education + Analytical Stretching, Alfredson Exercise Program + Health Education
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Zaragoza
Breast Cancer, Breast Cancer Female
Multicenter Study of Pharmacokinetic-Guided Docetaxel in Breast Cancer Patients Receiving Docetaxel and Cyclophosphamide
The purpose of this study is to adjust the amount of docetaxel participants receive based on the level of docetaxel measured in their blood. This method of dose adjustment is called pharmacokinetic (PK)-adjusted docetaxel.
- Trial name
- NCT02502864
- Testing
- Standard of Care: Docetaxel, Standard of Care: Cyclophosphamide, Function Assessment of Cancer Therapy (FACT) Surveys
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Osteopenia, Osteoporosis, Age-related Bone Loss
Senolytics to Improve Osteoporosis Therapy
This randomised clinical trial aims to study osteoporosis as a disease of accelerated skeletal aging caused by the accumulation of senescent cells within the skeleton and investigate the effects and safety of senolytics and…
- Trial name
- SENIOR (NCT06018467)
- Testing
- Dasatinib 100 Mg Oral Tablet, Quercetin 1.250 mg (oral), Nicotinamide Riboside 1g (oral)
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Odense University Hospital
NSTEMI - Non-ST Segment Elevation MI
The British Heart Foundation SENIOR-RITA Trial
SENIOR-RITA is a multicentre prospective open-label trial randomizing patients presenting with type 1 NSTEMI aged ≥75 years between invasive and conservative treatment strategies, to compare time from randomisation to…
- Trial name
- SENIOR-RITA (NCT03052036)
- Testing
- Coronary Angiography, Coronary revascularisation, Optimal Medical Therapy
- Where
- 40 sites in United Kingdom
- Volunteers
- 1,518 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Healthy Volunteers, Healthy Elderly
A Explorative Pilot Study to Gain Insights for a New Senior Milk Powder
The purpose of this interventional, single-arm pilot study aimed to evaluate the new product that newly developed contains a mixture of prebiotics and probiotics to gain insights of GI function acceptance, microbiological…
- Trial name
- NCT06646458
- Testing
- Healthy Elderly Volunteers
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Danone Nutricia
Hypertension, Stroke
Culturally Tailoring a Stroke Intervention in Community Senior Centers
Stroke is a cruel disease that disproportionately kills and disables African-Americans, Latinos, Chinese-Americans and Korean-Americans; seniors with high blood pressure are at particularly high risk.
- Conditions
- Hypertension, Stroke, Sedentary Lifestyle, Aged
- Trial name
- SPIRP (NCT02181062)
- Testing
- Walking Intervention
- Where
- 4 sites in United States
- Volunteers
- 240 people
- Sponsor
- University of California, Los Angeles
Aspiration Pneumonia
Eating Rehabilitation Training for Timely Removal of Nasogastric Tube in Elderly Patients
Aspiration pneumonia is a common complication in senior patients with high morbidity and mortality rate. The decline of physical function among elders can easily lead to swallowing disorders, and nasogastric (NG) tube insertion…
- Trial name
- NCT05810688
- Testing
- eating rehabilitation training
- Where
- Taiwan
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Mild Cognitive Impairment
Evaluation of Cognitive State in Senior Subjects Using Neurosteer EEG System
This is an observational study. Patients who fulfill all inclusion criteria and none of the exclusion criteria will be enrolled in the study, be neurologically evaluated and will go through EEG recordings while listening to an…
- Trial name
- NCT04683835
- Testing
- Neurosteer Aurora system
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Neurosteer Ltd.
Atrial Fibrillation
Edoxaban and Frailty in Senior Individuals
Edoxaban, has shown in clinical registration trials a significant reduction of major bleeding compared to warfarin, especially in elderly patients.
- Trial name
- ESCAPE (NCT03524924)
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- University of Padova
Alzheimer Disease, Dementia
Utilizing Senior Companions to Enhance Dementia Care
The inability of healthcare systems to effectively manage Alzheimer's disease and related dementias (ADRD) often results in families remaining unaware of important community-based, long-term services and supports (LTSS) that…
- Trial name
- NCT03667924
- Testing
- PorchLight Project
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
The Elderly (≥ 70 Years) With Essential Hypertension
Fimasartan in the Senior Subjects
The objective of this study is to confirm the noninferiority of the blood pressure lowering effect of fimasartan and evaluate its safety compared to perindopril in the elderly with essential hypertension.
- Trial name
- FITNESS (NCT03246555)
- Testing
- Fimasartan or Fimasartan/Hydrochlorothiazide, Perindopril or Perindopril/Indapamide
- Where
- South Korea
- Volunteers
- 241 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Balance, Postural, Gait
The Influence of Manual Therapy Applied to the Cervical Spine in the Prevention of Balance Disorders in the Elderly
Falling is a major trauma that can occur with aging, leading to very significant psychological and physical health effects with financial and societal consequences.
- Conditions
- Balance, Postural, Gait, Elderly
- Trial name
- ManEq (NCT05475652)
- Testing
- Manual therapy
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- EZUS-LYON 1
Osteoporosis, Frailty
Spitex-SpiTal-Autonomie-Reha-Kraft
The primary purpose of this study is to test if the STARK comprehensive autonomy health care package improves lower extremity function over time at 6 weeks, 3, 6 and 12 months after hip or pelvis fracture compared to the standard…
- Conditions
- Osteoporosis, Frailty, Hip Fractures
- Trial name
- STARK (NCT03154684)
- Testing
- STARK intervention, Standard of Care
- Where
- Switzerland
- Volunteers
- 5 people
- Sponsor
- University of Zurich
Elderly People, Falls
Analysis of the Biomechanics of Walking
The proportion of people aged 60 and over in the French population has increased from 18% in 1970 to over 22% in 2010. One major problem in the elderly is falling.
- Trial name
- NCT02547285
- Testing
- Shoes characteristics
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne