Clinical trials: Self-injury
Cornelia de Lange Syndrome
Use of N-Acetylcysteine in the Treatment of Repetitive and Self-Injurious Behaviors in Cornelia de Lange Syndrome
This research project is a randomized cross-over pilot trial which aims to test the efficacy of N-acetylcysteine (NAC) for the treatment of Repetitive Behaviors (RB) and self-injurious behavior (SIB) in patients with Cornelia de…
- Trial name
- NCT04381897
- Testing
- N-acetyl cysteine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Johns Hopkins University
Leadership, Self-Harm
Implementing Evidence-Based Nursing: Leadership and Organizational Change for Implementation
This study aims to find out whether a leadership and organizational development program called the LOCI (Leadership and Organizational Change for Implementation) strategy can help nurses and their managers use the best available…
- Conditions
- Leadership, Self-Harm, Malnutrition Elderly
- Trial name
- LOCI-FIN-P (NCT07378696)
- Testing
- Leadership and organizational change for implementation
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- Jaakko Varpula
Mood Disorders, Depression
Use of tDCS Applied to the Orbitofrontal Cortex to Improve Risky Decision-making in a Clinical Population
Decision-making is a complex cognitive function that has been the subject of extensive scientific research in the fields of cognitive and computational neuroscience.
- Conditions
- Mood Disorders, Depression, Suicide
- Trial name
- tDCSDeMOStim (NCT06110559)
- Testing
- Active transcranial direct current stimulation (tDCS)
- Where
- France
- Volunteers
- 124 people
- Sponsor
- Centre Hospitalier St Anne
Depressive Disorder
M3VAS Validation in Polish Population
Low mood and anhedonia represent the fundamental symptoms of major depressive disorder (MDD). Nevertheless, there is currently no standardized visual analogue scale available to assess the extent of both symptoms concurrently.
- Trial name
- NCT06412562
- Testing
- The Maudsley 3-item Visual Analogue Scale (M3VAS)
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Medical University of Gdansk
Suicide, Attempted, Substance-Related Disorders
Effectiveness of Cognitive Therapy for Suicide Attempters With Drug Dependence Disorder
This study will examine the effectiveness of combining cognitive therapy with enriched usual care for preventing subsequent suicide attempts in people with a drug dependence who have recently attempted suicide.
- Trial name
- NCT00218725
- Testing
- Cognitive Therapy, Enriched Care
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Pennsylvania
Episiotomy Wound
Chicken Model in Teaching Episiotomy Repair
The aim of this study is to determine the effect of chicken use in episiotomy repair training of midwifery students on students' satisfaction, self-confidence and anxiety levels.
- Trial name
- NCT05502640
- Testing
- Education model, Routine Education model
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ankara University
Suicidal Thoughts and Behaviors, Social Isolation
Qnnections: Refinement and Pilot Trial of a Suicide Prevention Intervention to Increase Social Connection
Despite the high risk of suicide among LGBTQ+ Veterans, there is currently no suicide-focused intervention for this population. This study will refine and pilot Qnnections, a novel group-based suicide prevention intervention that…
- Trial name
- Qnnections (NCT06803329)
- Testing
- Qnnections, Enhanced Usual Care
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- VA Office of Research and Development
Suicide, Depressive Disorder, Major
Promote Access to Stop Suicide: Comparison of Follow up Services for Youth at Risk for Suicide
This research study is designed to answer specific questions about new ways to provide services for youth at-risk of suicide.
- Conditions
- Suicide, Depressive Disorder, Major, Anxiety Disorders, Suicidal Ideation
- Trial name
- PASS (NCT03016572)
- Testing
- Standard of Care, Crisis Intervention, Wraparound Services
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- The Cleveland Clinic
Mental Health, HIV
"Gwan Enjoy Life:" A Peer-Supported Mental Health Mentoring Intervention to Improve Engagement in Care Among Sexual Minority Men Living With HIV in Jamaica
Sexual minority men (SMM) in Jamaica face many challenges that affect their health and well-being. Although they make up a relatively small part of the population, they are much more likely to be living with HIV than the general…
- Conditions
- Mental Health, HIV, Pyschological Distress, Suicidal Ideation
- Trial name
- GwanEnjoyLife (NCT07762612)
- Testing
- Gwan Enjoy Life Interveniton
- Where
- Jamaica
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
PTSD and Trauma-related Symptoms, PTSD
A Pilot Research Project on Outcome of Trauma Informed Stabilization Treatment (TIST) for Adults with Complex Trauma Symptoms After Childhood Trauma, At the Department of Trauma Treatment, Modum Bad, Norway
The purpose of the study is to examine the effects of residential group and individual Trauma Informed Stabilization Treatment (TIST) for complex symptoms in adult survivors of childhood trauma in a naturalistic observational…
- Trial name
- NCT06719167
- Testing
- Psychoterapy
- Where
- Norway
- Volunteers
- 32 people
- Sponsor
- Modum Bad
Suicide, Suicidal Ideation
Brief Cognitive Behavioral Therapy for Military Populations
The primary purpose of this study is to compare the effectiveness of brief cognitive-behavioral therapy (B-CBT) for the treatment of suicidality, including suicidal ideation and attempts (regardless of Axis I or II diagnosis)…
- Trial name
- NCT02038075
- Testing
- Brief Cognitive Behavioral Therapy (BCBT), Treatment As Usual (TAU)
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- University of Utah
Suicide, Firearm Injury
Home Safety Intervention
Access to lethal methods of self-harm such as firearms and medications increases risk for suicide. As such, VA/DoD guidelines for the care of individuals with elevated suicide risk include recommendations that clinicians deliver…
- Conditions
- Suicide, Firearm Injury, Overdose
- Trial name
- HSI (NCT06216327)
- Testing
- household safety intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- VA Office of Research and Development
Trauma, Childbirth
Effect of Motivational Interviews on Childbirth Perception and Childbirth Self-Efficacy
Aim: The aim of this study to determine the effect of motivational interviews on the perception and self-efficacy of birth in nullipars with a perception of traumatic birth.
- Conditions
- Trauma, Childbirth, Self Efficacy
- Trial name
- NCT05216783
- Testing
- Motivational Interviews
- Where
- Turkey (Türkiye)
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Inonu University
Suicidal Ideation, Depression
Exploring the Effectiveness of a Suicide Ideation Prevention Program: Reframe-IT+
Suicide is a leading cause of death among young people, with worldwide prevalence rates of suicidal ideation, suicidal ideation with a plan, and suicide attempts in youth aged 14-21 years.
- Conditions
- Suicidal Ideation, Depression, Anxiety, Hopelessness
- Trial name
- Reframe-It+ (NCT06759441)
- Testing
- Reframe-It+
- Where
- Chile
- Volunteers
- 75 people
- Sponsor
- Universidad de los Andes, Chile
Borderline Personality Disorder
DBT for Chronically Self-harming Individuals With BPD: Evaluating the Clinical & Cost Effectiveness of a 6 mo. Treatment
Standard one-year dialectical behaviour therapy (DBT), which has four components, is an effective treatment for people with borderline personality disorder.
- Trial name
- FASTER-DBT (NCT02387736)
- Testing
- Dialectical Behaviour Therapy-6 months, Dialectical Behaviour Therapy-12 months
- Where
- 2 sites in Canada
- Volunteers
- 240 people
- Sponsor
- Centre for Addiction and Mental Health
Major Depressive Disorder, Suicidal Behavior
Basal Plasma Lithium Levels and Suicidal Events
Suicidal behavior is a major public health issue and there are currently no specific treatments for it. However, lithium, the reference treatment for bipolar disorder, have been shown to be effective in preventing suicidal risk.
- Conditions
- Major Depressive Disorder, Suicidal Behavior, Bipolar Disorder
- Trial name
- LIPS (NCT05409794)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 158 people
- Sponsor
- University Hospital, Montpellier
Post-traumatic Stress Disorder
Community Self-help Using Thought Field Therapy in a Traumatised Population in Uganda: a Randomised Trial
Thought Field Therapy (TFT) is a simple technique that involves tapping on points of the body corresponding to the meridians used in acupuncture.
- Trial name
- NCT01681628
- Testing
- Thought Field Therapy.
- Where
- Uganda
- Volunteers
- 256 people
- Sponsor
- Thought Field Therapy Foundation (UK) Ltd
Self Injurious Behavior, Suicide
Real-time Examination of Skills and Coping Use in Teen's Everyday Lives
The goal of this clinical trial is to compare two core intervention skills among adolescents with a history of engaging in at least 3 lifetime incidents of self-inflicted injury (SII), at least one of which was a suicide attempt…
- Trial name
- RESCUE (NCT06720753)
- Testing
- Opposite to emotion action, GIVE
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Utah
Chronic Pain, Suicidal Ideation
Mindfulness for Pain and Suicide
The proposed study will assess the feasibility and acceptability of a mindfulness-based intervention to reduce functional impairment from chronic pain and risk of suicide.
- Conditions
- Chronic Pain, Suicidal Ideation, Suicide, Attempted, Opioid Use
- Trial name
- NCT05286112
- Testing
- Mindfulness-Based Cognitive Therapy (MBCT), Health Education
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Canandaigua VA Medical Center
Suicide Prevention, Ketamine
Esketamine Versus Crisis Response Planning Versus Enhanced Treatment as Usual for Suicide Prevention: A Pragmatic Randomized Trial in a Brazilian Municipality (SAVE)
The SAVE study will test whether a single esketamine infusion or a single Crisis Response Planning session, each added to enhanced treatment as usual, reduces future suicide-related events compared with enhanced treatment as…
- Conditions
- Suicide Prevention, Ketamine, Crisis Response Plan
- Trial name
- SAVE (NCT07120477)
- Testing
- Intravenous Esketamine, Crisis Response Planning (CRP), Enhanced Treatment as Usual (eTAU)
- Where
- Brazil
- Volunteers
- 478 people
- Sponsor
- University of Sao Paulo
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