Clinical trials: Self-injury
Posttraumatic Stress Disorder
Couple HOPES (Helping Overcome PTSD and Enhance Satisfaction)
Posttraumatic stress disorder (PTSD) is a common and disabling condition associated with intimate relationship problems and mental health problems in partners of those with PTSD.
- Trial name
- HOPES (NCT04231578)
- Testing
- Couple HOPES Guided, Internet-Delivered, Self-Help Intervention
- Where
- Canada
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Suicidality
A Study to Assess the Validation and Mapping of the Suicide Ideation and Behavior Assessment
The main purpose of this cross-sectional study is to generate data to support the psychometric properties of the Suicide Ideation and Behavior Assessment Tool (SIBAT) and validate its use in participants at imminent risk of…
- Trial name
- NCT03085108
- Testing
- No Intervention
- Where
- 4 sites in United States
- Volunteers
- 130 people
- Sponsor
- Janssen Scientific Affairs, LLC
Pressure Injury, Wound
Pressure Injury Prediction and Education Model Using a Mobile Application System
Pressure injuries are common in the elderly and patients who reduced physical activities. Its complications significantly impact the health care system and social burden, even causing the death rate to be as high as 68%.
- Trial name
- NCT05357391
- Testing
- The Pressure Injury Prediction and Education model using a mobile application system
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
Suicide, Suicidal Ideation and Behavior
Pilot Study on Follow-Up of (Acutely) Suicidal Individuals From the Flemish Suicide Helpline
This pilot study aims to assess the acceptance, feasibility, and added value of follow-up calls at the suicide helpline, Zelfmoordlijn 1813, in Flanders (Belgium).
- Conditions
- Suicide, Suicidal Ideation and Behavior, Crisis Intervention
- Trial name
- CONT-1813 (NCT07343258)
- Testing
- Callbacks from the Zelfmoordlijn 1813
- Where
- Belgium
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Ghent
Military Service Members at Elevated Suicide Risk
Increasing Help-Seeking in Military Service Members
There is sufficient evidence that military service members markedly underutilize behavioral health care services, in part, due to stigma.
- Trial name
- NCT04043936
- Testing
- Cognitive Bias Modification Intervention for Help-Seeking Stigma, Self-Directed Psychoeducation
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- Florida State University
PTSD, Military Activity
Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms
Art therapy is used across the Military Health System for treatment of posttraumatic symptoms, but there is limited research on how art therapy is able to restore emotional expression and regulation in service members.
- Conditions
- PTSD, Military Activity, Post-Traumatic Headache, Posttraumatic Stress Disorder
- Trial name
- NCT05414708
- Testing
- Art Therapy
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Walter Reed National Military Medical Center
Chronic Pain Syndrome, Chronic Pain
Supporting Self-management of Chronic Pain
Does the Navigator Tool Intervention improve communication regarding self-management during consultations between healthcare professionals and people with chronic pain? As there is usually no cure for chronic pain, healthcare…
- Conditions
- Chronic Pain Syndrome, Chronic Pain, Chronic Pain Due to Injury, Chronic Pain Due to Trauma
- Trial name
- NCT03119896
- Testing
- The Navigator Tool Intervention
- Where
- 5 sites in United Kingdom
- Volunteers
- 35 people
- Sponsor
- Pain Concern
Prader-Willi Syndrome
Dose Clinical Trial of Guanfacine Extended Release for the Reduction of Aggression and Self-injuries Behavior Associated With Prader-Willi Syndrome
This is a placebo-controlled clinical trial to assess the utility of Guanfacine Extended Release (GXR) in the management of patients with Prader Willi Syndrome (PWS) who have significant aggression or self-injury.
- Trial name
- NCT04066088
- Testing
- Guanfacine extended release (GXR)
- Where
- United States
- Sponsor
- NYU Langone Health
Suicidal Ideation, Suicidal Behavior
The "AIM Study": Investigating Whether Actigraphy and Ideation Measures Can Promote Patient Safety
This is a research project looking at whether measuring movements or responses to certain questions can help predict suicidal thoughts or actions.
- Conditions
- Suicidal Ideation, Suicidal Behavior, Mental Health Symptoms, Mental Health Hospitalizations
- Trial name
- AIM (NCT03080168)
- Testing
- Actigraph
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- VA Office of Research and Development
Major Depressive Disorder, Suicide
i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial
Approximately four thousand Canadians die by suicide every year, and suicide is the second leading cause of death in youth and young adults (15-34 years).
- Conditions
- Major Depressive Disorder, Suicide, Treatment Resistant Depression
- Trial name
- Ket-CBT (NCT06480500)
- Testing
- Ketamine hydrochloride, i-CBT (Internet-based Cognitive Behavioural Therapy), Midazolam Hydrochloride
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- University Health Network, Toronto
PTSD
Testing a Self-Management App for Symptoms of Posttraumatic Stress
The purpose of this study is to evaluate the acceptability and efficacy of a self-guided behavioral health tool delivered by mobile app (called "Renew") for people who are experiencing symptoms of posttraumatic stress.
- Trial name
- NCT04155736
- Testing
- Renew
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Palo Alto Veterans Institute for Research
Bipolar Depression, Suicidal Ideation
NRX100 vs. Placebo for Rapid Stabilization of Acute Suicidal Ideation and Behavior in Bipolar Depression
NMDA antagonist drugs have increasingly been demonstrated to reduce symptoms of depression and suicidal ideation. NeuroRx has developed a sequential therapy consisting of IV NRX-100 (ketamine HCL) for rapid stabilization of…
- Trial name
- SevereBD (NCT03396601)
- Testing
- Ketamine Hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- NeuroRx, Inc.
Suicidal Ideation, Suicide Attempt
A Randomized Controlled Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior
This study aims to evaluate the acceptability, safety, and efficacy of a smartphone-delivered intervention called Therapeutic Evaluative Conditioning for Suicide (TEC-S) in reducing suicidal thoughts and behaviors (STB) among…
- Trial name
- NCT06686901
- Testing
- Smartphone-delivered Therapeutic Evaluative Conditioning for Suicide (TEC-S), Smartphone-delivered inactive Therapeutic Evaluative Conditioning
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Suicide
Increasing Treatment Seeking Among Suicidal Veterans Calling the Crisis Line
The goal of this research plan is to test the effectiveness of a brief, cognitive behavioral (CB) intervention to promote behavioral health treatment engagement among at-risk Veterans who call the Crisis Line but are resistant to…
- Trial name
- NCT01771965
- Testing
- CB Intervention
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- VA Office of Research and Development
Suicidal Ideation, Eating Disorder Symptom
Pilot of Reconnecting to Internal Sensations and Experiences in Undergraduates
Project RISE is a randomized control trial. The intervention consists of four modules that focus on multiple aspects of interoception including: body awareness, body sensations/movement, eating, health and self-care, emotional…
- Trial name
- RISE (NCT05285111)
- Testing
- Reconnecting to Internal Sensations and Experiences, Healthy Habits
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Auburn University
Bladder Outlet Obstruction, Multiple Sclerosis
GentleCath™ for Men Intermittent Catheter With FeelClean™ Technology
Male self catherterisng observational study.
- Conditions
- Bladder Outlet Obstruction, Multiple Sclerosis, Cauda Equina Syndrome, Enlarged Prostate With Lower Urinary Tract Symptoms
- Trial name
- NCT05470751
- Testing
- Intermittent self-catheterisation
- Where
- 16 sites in United States, France and 1 more
- Volunteers
- 72 people
- Sponsor
- ConvaTec Inc.
Depression
Village-based Intervention for Late-life Depression
Investigators aimed to examine the feasibility and effectiveness of a village-based multilevel intervention for late-life depression.
- Trial name
- NCT04013165
- Testing
- Active control, Village-based intervention
- Where
- South Korea
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Recreational Drug Use, Sexual Violence
Evaluation of Teen Connection Project for Trans and Gender Minority Youth
The purpose of this project is to develop and evaluate an online mentoring and skill-building program for transgender and/or gender minority youth (TGMY) ages 14 to 18, the Teen Connection Project (TCP).
- Conditions
- Recreational Drug Use, Sexual Violence, Victimisation, Depressive Symptoms
- Trial name
- TCP (NCT06587139)
- Testing
- Teen Connection Project (TCP)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Suicidal Behavior
Brief Intervention and Contact Program Main Trial
Suicide is a significant public health concern and causes approximately 1.5% of all deaths in the general population in Canada. Research shows that for individuals with comorbid psychiatric illness and suicidal behaviour, the…
- Trial name
- BIC (NCT05656781)
- Testing
- Brief Intervention and Contact (BIC) based on Word Health Organization (WHO)
- Where
- Canada
- Volunteers
- 132 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Suicide
Alaska Native Collaborative Hub for Resilience Research
The goal of the Alaska Native Resilience Research Study (ANRRS) is to identify community-level protective factors that can most effectively reduce co-occurring youth suicide and alcohol risk.
- Trial name
- ANCHRR (NCT03131739)
- Volunteers
- 585 people
- Sponsor
- University of Alaska Fairbanks
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