Clinical trials: Self-injurious Behavior
Borderline Personality Disorder
Ketamine in Borderline Personality Disorder
The purpose of this study is to test the potential of the rapid-acting anti-depressant ketamine to decrease suicidality in Borderline Personality Disorder (BPD).
- Trial name
- NCT03395314
- Testing
- Ketamine, Midazolam
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- Yale University
Suicide
Evaluation of a Gatekeeper Training for Pharmacists
This study aims to investigate to what extent a gatekeeper training (e-learning) for pharmacists and PTA is effective in changing the attitudes, knowledge, and self-efficacy.
- Trial name
- NCT05991635
- Testing
- Gatekeeper training (e-learning)
- Where
- Belgium
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- University Ghent
Suicide
eLearning for Suicide Prevention
Project WISE (Workplace Integrated Support \& Education) includes developmental and pilot research to create an e-learning training in suicide safety planning enhanced with novel skill-building technologies that can be integrated…
- Trial name
- NCT05178121
- Testing
- eLearning Training in Suicide Safety Planning
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Washington
Suicidal Ideation, Suicide Attempt
The Epidemiology of Suicide Attempts and Suicidal Thoughts in Flanders
The objective of this study is to collect data in Flanders on the incidence of suicide attempts and suicidal ideation across various healthcare settings.
- Conditions
- Suicidal Ideation, Suicide Attempt, Multicenter Study, Epidemiological Study
- Trial name
- BC-03869 (NCT07021404)
- Testing
- Semi-structured interview (Guideline for Suicide care and Evaluation =LOES)
- Where
- 33 sites in Belgium
- Volunteers
- 50,000 people
- Sponsor
- University Hospital, Ghent
Suicide, Attempted, Suicidal Ideation
Motivational Interviewing to Address Suicidal Ideation for Veterans at High Risk for Suicide
The purpose of this project is to conduct a randomized control trial with 470 Veterans to examine the impact of a revised version of Motivational Interviewing to Address Suicidal Ideation (MI-SI-R) on risk for suicide attempts…
- Trial name
- MI-SI (NCT05256940)
- Testing
- Motivational Interviewing to Address Suicidal Ideation- Revised (MI-SI-R), Enhanced usual care (EUC)
- Where
- 3 sites in United States
- Volunteers
- 368 people
- Sponsor
- VA Office of Research and Development
Suicidal Ideation, Alcohol Drinking
Computerized DBT Skills Training for Suicidal and Heavy Episodic Drinkers
Alcohol use is considered to be a significant risk factor among those who die by suicide, especially among those who drink to regulate their emotions.
- Trial name
- NCT02932241
- Testing
- Computerized Dialectical Behavior Therapy Skills Training
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Washington
Suicide, Attempted
Inpatient Cognitive-Behavioral Therapy to Reduce Suicide Risk Post-Discharge
The goal of this randomized-controlled trial is to determine whether adding brief cognitive-behavioral therapy for suicide prevention (BCBT) to inpatient treatment improves suicide-related outcomes after the person leaves the…
- Trial name
- NCT04168645
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- Hartford Hospital
Suicidal Ideation
Adjunctive Duration-doubled tDCS for the Treatment of Depressive Patients With Suicidal Ideation
In this double-blinded, randomized, sham-controlled trial, the investigators aim to determine the acute effectiveness of duration-doubled tDCS on suicidal ideation in patients with MDD.
- Trial name
- NCT05555927
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Shanghai Mental Health Center
Suicide
PHARM-S.A.V.E.S: Suicide Prevention Training
This is a pilot Randomized Controlled Trial (RCT) in which 150 pharmacy staff members will be randomized to an experimental or control group and data on suicide prevention communication and secondary outcomes will be collected…
- Trial name
- NCT05128227
- Testing
- Pharm-SAVES, Interactive video cases
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Suicide, Suicidal Ideation
Zero Suicide Plus KICKS
Integrating Intergenerational Cultural Knowledge Exchange with Zero Suicide is an innovative study in a Southwestern tribal nation that incorporates Zero Suicide into Indian Health Services (IHS) primary care settings.
- Conditions
- Suicide, Suicidal Ideation, Suicidal Intention, Suicidal and Self-injurious Behavior
- Trial name
- NCT03924037
- Testing
- Intergenerational Knowledge Sharing group, Support group
- Where
- United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Depression
Assessing Treatment Emergent Suicidal Ideation in Patients With Major Depression
This study will develop a new methodology to evaluate any treatment-emergent suicidal ideation that might occur when an antidepressant treatment has been started and/or during times when doses are increased in patients with major…
- Trial name
- SAMS (NCT00532103)
- Where
- 15 sites in United States
- Volunteers
- 300 people
- Sponsor
- National Institute of Mental Health (NIMH)
Suicidal Ideation, Thoughts of Self Harm
Virtual Hope Box - Effectiveness of a Smartphone App for Coping With Suicidal Ideation
A hope box or self soothing kit is a therapeutic tool employed by clinicians with patients expressing suicidal ideation, significant distress, or otherwise at risk of suicidal or non-suicidal self harm.
- Conditions
- Suicidal Ideation, Thoughts of Self Harm, Coping
- Trial name
- VHB-RCT (NCT01982773)
- Testing
- Virtual Hope Box Smartphone App, Enhanced Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 118 people
- Sponsor
- National Center for Telehealth and Technology
Anxiety, Suicidal Ideation
Climate Anxiety in a Young Population at Risk of Suicide
Climate change has become a major source of concern, particularly among younger generations who are facing the progressive degradation of ecosystems, loss of biodiversity, and alarming environmental information disseminated…
- Conditions
- Anxiety, Suicidal Ideation, Mental Health Issue, Environmental Exposure
- Trial name
- Anx-RS (NCT07305688)
- Testing
- Columbia Suicide Severity Rating Scale, Climate Change Anxiety Scale - French version, State-Trait Anxiety Inventory, French version
- Where
- France
- Volunteers
- 108 people
- Sponsor
- Centre Hospitalier Esquirol
Depressive Disorder
M3VAS Validation in Polish Population
Low mood and anhedonia represent the fundamental symptoms of major depressive disorder (MDD). Nevertheless, there is currently no standardized visual analogue scale available to assess the extent of both symptoms concurrently.
- Trial name
- NCT06412562
- Testing
- The Maudsley 3-item Visual Analogue Scale (M3VAS)
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Medical University of Gdansk
Suicide, Depression
Engaging Suicidal Patients in Mental Health Treatment
The investigators will identify characteristics of suicidal patients who do or do not attend a first mental health visit following referral using administrative data.
- Conditions
- Suicide, Depression, Mental Health Impairment, Suicidal Ideation
- Trial name
- NCT05021224
- Testing
- Caring Contacts, Reminders, Informational Poster
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Suicide, Attempted, Suicidal Ideation
Brief Cognitive Behavioral Therapy Replication Trial
The overall goal for the proposed project is to test the effectiveness of BCBT for the prevention of suicide attempts in a sample of treatment-seeking U.S. military personnel and veterans.
- Trial name
- NCT03769259
- Testing
- Brief Cognitive Behavioral Therapy (BCBT), Present-Centered Therapy (PCT), Treatment as Usual (TAU)
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Utah
Insomnia, Suicidal Ideation
RCT of Brief CBT-I in Primary Care Veterans With Suicidal Thoughts
There is a strong association between insomnia and suicidal thoughts and behaviors. Insomnia also frequently co-occurs with other common conditions associated with suicide such as depression and posttraumatic stress disorder.
- Trial name
- NCT03603717
- Testing
- Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene
- Where
- 3 sites in United States
- Volunteers
- 283 people
- Sponsor
- VA Office of Research and Development
Psychiatric Disorder
Evaluation of a Modularized Cognitive Behavioral Group Therapy Programme for Young Adults (CHANGE-Study)
This prospective, non-randomised, pre-post feasibility study evaluates CHANGE, a novel 8-session modularized cognitive behavioral group psychotherapy for young adults (18-25 years) with psychiatric disorders receiving inpatient…
- Trial name
- CHANGE (NCT07772180)
- Testing
- CHANGE - modularized group psychotherapy
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Max-Planck-Institute of Psychiatry
Suicide
Alliance With Therapeutic Entourage in Support of Young Suicidal
Regardless of age, the quality of hospital care, the confidence that the young can have in the health care team, joining parents are pivotal elements and influence followed.
- Trial name
- IPSI2 (NCT02524535)
- Testing
- Therapeutic alliance
- Where
- France
- Volunteers
- 292 people
- Sponsor
- University Hospital, Caen
Unipolar Depression, Impulsive Behavior
How to Reduce Suicidal Thoughts and Impulsivity in Depression
The study aims at investigating if tDCS applied to left DLPFC or to right OFC to treatment as usual is effective in reducing severe suicidal ideas in major depressive episode.
- Conditions
- Unipolar Depression, Impulsive Behavior, Suicidal Ideation
- Trial name
- DEPIMPULSE (NCT05894980)
- Testing
- active tDCS stimulating left DLPFC, active tDCS stimulating right OFC
- Where
- 4 sites in France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon