Clinical trials: Self-harm Behavior
Depression
Exploration of the Relationship Between Inflammation and Integrity of the Blood-Brain Barrier in Suicidal Behaviour
Recent studies have revealed an association between history of suicide attempt and inflammatory markers in both the cerebrospinal fluid and the plasma.
- Trial name
- IBIS (NCT04137458)
- Testing
- Biological analysis
- Where
- France
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Self Harm
Occupational Therapy for Children and Young People Who Self-harm: A Qualitative Study
The goal of this qualitative observational study is to explore the experiences of children and their carers, receiving occupational therapy for self-harm and the experiences of health professionals delivering these interventions.
- Trial name
- NCT06317155
- Testing
- Occupational therapy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Autism Spectrum Disorder
Development and Validation of a System for the Anticipation of Challenging Behaviors
Most people with autism spectrum disorder (ASD) present at least one form of challenging behavior (CB). Self-injurious, aggressive, and disruptive CBs linked with social interaction, community-based service exclusion, and a life…
- Trial name
- NCT05340608
- Testing
- Smart, non-invasive shirt - Physiological parameters, Smart, non-invasive shirt - Relation with challenging behaviors, Smart, non-invasive shirt - Proof of Concept
- Where
- Israel
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Ariel University
Suicidal Ideation, Suicide
The Impact of Ketamine on the Reward Circuitry of Suicidal Patients
Every 40 seconds, someone in the world dies by suicide. There is a lack of effective and safe antisuicidal agents for preventing suicide attempts.
- Trial name
- NCT02532153
- Testing
- Ketamine Hydrochloride
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Suicide
Veterans Coping Long-term With Active Suicide
The proposed study seeks to test the efficacy of an intervention to reduce suicide behaviors in Veterans. The Veterans Coping Long Term with Active Suicide Program (CLASP-VA) is an innovative, telephone-based intervention that…
- Trial name
- CLASP-VA (NCT01894841)
- Testing
- Coping Long Term with Active Suicide (CLASP), Safety Assessment and Follow Up Evaluation
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Depression, Anxiety, Self-Injurious Behavior
Brief App-based Mood Monitoring and Mindfulness Intervention for First-year College Students
The investigators examined whether brief, app-based interventions were helpful in alleviating mental health symptoms during the transition to college.
- Trial name
- NCT06348277
- Testing
- Mindfulness plus mood monitoring, Mood monitoring
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Lawrence University
Relatives
Family Connections for Caregivers of People With Suicidal Behavior
The aim of our study is to verify the efficacy of the Family Connections intervention for relatives of people diagnosed with suicidal behavior disorder in a randomized control trial with a Spanish participants.
- Trial name
- NCT05157607
- Testing
- Family Connections Protocol for Relatives of Patients with SBD., Treatment as Usual Optimized Protocol (TAU-O)
- Where
- Spain
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Suicide
School-based Comprehensive Suicide Intervention in Shanghai, China
The primary aim of this study is to examine whether a school-based suicide intervention is effective in reducing suicide related risk factors in a population of middle and high students.
- Trial name
- NCT01598519
- Testing
- suicide intervention
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Suicidal Ideation
Career Enhancement Training Study (USAF)
A study evaluating a training program to decrease risk for suicidal thoughts and behaviors among early career trainees in the United States Air Force.
- Trial name
- CETS (NCT04067401)
- Testing
- Wingman Connect, Stress Management
- Where
- United States
- Volunteers
- 1,485 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Depression, Suicidality
Development and Preliminary Trial of a Brief, Portable Health Intervention for Rural Sexual Minority Emerging Adults
The purpose of this study is to test the feasibility of writing interventions specifically designed for lesbian, gay, and bisexual (LGB) emerging adults (ages 18-29) that are aimed at improving the outcomes: depression…
- Conditions
- Depression, Suicidality, Substance Abuse, HIV
- Trial name
- Project LEAP (NCT03751020)
- Testing
- Expressive Writing (EW) Intervention, Self-Affirmation (SA) Intervention, Control
- Where
- 3 sites in United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yale University
Attempt Suicide
Genetic Variants Associated With Adolescent Suicide Attempts
Suicidal behaviors is known to aggregate in families. The purpose of this study is to evaluate association between common polymorphisms in genes important for neurobiological pathways linked to suicidal behaviors and suicide…
- Trial name
- VGTSA (NCT02001649)
- Testing
- SNP Genotyping
- Where
- France
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Suicide, Nurse's Role
Nurse Suicide: Physiologic Sleep Health Promotion Trial
The purpose of this study is to identify factors (sleep, psychiatric characteristics, stressful life events, and work environment characteristics) that potentiate or mitigate adverse effects of real-world stressors that…
- Conditions
- Suicide, Nurse's Role, Work Environment Adverse Effects, Sleep
- Trial name
- NCT06079853
- Testing
- PureSomni Sleep Health Product Kit
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Columbia University
Substance Abuse, Suicide
Functional Connectivity Alterations in Suicidal Patients Among Opioid Users
Suicide is the 10th leading cause of death for Americans of all ages and more people in the United States now die from suicide than die from car accidents.
- Conditions
- Substance Abuse, Suicide, Depression
- Trial name
- NCT05489042
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Caregivers, Decision Making
"Safety in Dementia": An Online Caregiver Intervention
In an online randomized trial of Safety in Dementia with national recruitment and longitudinal follow-up, we will recruit informal caregivers of community-dwelling adults with dementia who have firearm access.
- Conditions
- Caregivers, Decision Making, Alzheimer Disease, Social Media
- Trial name
- NCT05173922
- Testing
- Safety in Dementia
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
People Who Inject Drugs
Evaluation of an Educational Intervention on Abscesses in People Who Self-inject Drugs
The goal of this cluster randomised controlled trial (cRCT) is to to evaluate the effectiveness of an educational intervention combining training in hand-washing with the supply of MONO-RUBs on the reduction of skin abscesses…
- Trial name
- HAWA (NCT06131788)
- Testing
- Educational hand hygiene intervention
- Where
- 22 sites in France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Adverse Mental/Physical Effects of Low Dose S. Tortuosum.
Safety Study of the Effect of Scelectium Tortuosum (as Zembrin®)in Aged Normals
Phosphodiesterase is a candidate for the Rx \& prevention of cognitive and psychotic disorders. Since caffeine targets primarily PDE4(Phosphodiesterase subtype 4), caffeine analogs have been developed to mimic the actions of…
- Trial name
- NCT01805518
- Testing
- Scelectium Tortuosum
- Where
- Puerto Rico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Woodbury, Michel, M.D.
Suicide, Depression
Engaging Suicidal Patients in Mental Health Treatment
The investigators will identify characteristics of suicidal patients who do or do not attend a first mental health visit following referral using administrative data.
- Conditions
- Suicide, Depression, Mental Health Impairment, Suicidal Ideation
- Trial name
- NCT05021224
- Testing
- Caring Contacts, Reminders, Informational Poster
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Suicidal Ideation
Evaluation of Creative Materials Supporting Healthcare Professionals in Discussing Suicidality in Children and Adolescents
Preliminary research clearly indicates a significant shortage of evidence-based tools and interventions specifically targeting suicidality among children and adolescents.
- Trial name
- NCT07043231
- Testing
- Creative materials
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Ghent
Inflammatory Bowel Diseases, Depressive Episode
Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health
This study is a large population-based analysis in the United Kingdom (UK) using routine primary care data to investigate the impacts on quality-of-life outcomes and use of healthcare services in people aged 5 - 25 years…
- Conditions
- Inflammatory Bowel Diseases, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorder
- Trial name
- NCT05206734
- Testing
- No specific intervention
- Where
- United Kingdom
- Volunteers
- 19,469 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Nonsuicidal Self-injury, Suicidal Ideation
Addressing Nonsuicidal Self-injury in Schools
The aim of this study is to study the effectiveness of a whole-school approach that addresses non-suicidal self-injury and targets adolescents, parents and teachers.
- Conditions
- Nonsuicidal Self-injury, Suicidal Ideation, Stigmatization, Help-Seeking Behavior
- Trial name
- NCT05935345
- Testing
- Addressing NSSI in schools, Control condition
- Where
- Sweden
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Region Östergötland