Clinical trials: Self-Injurious Behavior
Alcohol Use, Suicidal Ideation/Behavior
Examining the Relationship Between Ongoing Alcohol Use, Suicidal Thoughts and Behaviors and Related Constructs, and Behavioral Economic Decision-Making
The purpose of this single groups trial is to (Aim 1) determine relationships between alcohol use, suicidal thoughts and behaviors (STBs), and behavioral economic decision-making in a community sample (N = 100) of alcohol using…
- Trial name
- NCT06845761
- Testing
- Self-Guided Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Mark J Rzeszutek, PhD
Substance Abuse, Juvenile Delinquency
The Community Youth Development Study: A Test of Communities That Care
The Community Youth Development Study is an experimental test of the Communities That Care (CTC) prevention planning system. It has been designed to find out if communities that were trained to use the CTC system improved public…
- Conditions
- Substance Abuse, Juvenile Delinquency, Sexual Behavior, Criminal Behavior
- Trial name
- CYDS IV (NCT01088542)
- Testing
- Communities That Care
- Where
- United States
- Volunteers
- 52,323 people, healthy volunteers welcome
- Sponsor
- University of Washington
Suicide Prevention
A Novel Cognitive Reappraisal Intervention for Suicide Prevention
The goal of this trial is to refine and test a novel emotion-regulation based psychosocial intervention designed to reduce suicide risk in middle-aged and older adults (50-90 years old) who have been discharged after a…
- Trial name
- CRISP (NCT03026127)
- Testing
- Cognitive Reappraisal Intervention for Suicide Prevention, Supportive Therapy
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Weill Medical College of Cornell University
Depression and Suicide
Effects of Transcranial Direct Current Stimulation (tDCS) in the Management of Suicidal Ideation
The main objective of this study is to demonstrate that 15 transcranial direct current stimulation (tDCS) sessions of 30 minutes at 2 mA intensity are effective to reduce suicidal ideation
- Trial name
- tDCS-IDSDEP (NCT06009523)
- Testing
- Transcranial direct current stimulation
- Where
- 2 sites in France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Henri Laborit
Suicide, Attempted, Mood Disorders
Strategic Disclosure Intervention for Suicide Attempt Survivors
While suicide prevention depends on people disclosing suicidal thoughts and behaviors in order to get help, those who talk about their suicidality also face negative responses from the people who they tell.
- Trial name
- NCT05018897
- Testing
- To Share or Not to Share, Peer Support
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Illinois Institute of Technology
Depression, Pregnancy Related
Preventing Depressive Relapse in Pregnant Women With Recurrent Depression
The purpose of this investigation is to conduct a pragmatic effectiveness trial comparing digital mindfulness-based cognitive therapy (MBCT) plus usual care to usual care (UC) only among euthymic pregnant women with recurrent…
- Conditions
- Depression, Pregnancy Related, Antenatal Depression
- Trial name
- NCT03623620
- Testing
- Digital Delivery of Mindfulness-Based Cognitive Therapy
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Massachusetts General Hospital
Suicidal Ideation
Compassion Meditation and ReliefLink App for Suicidal, Low-Income, African Americans
The purpose of this study is to conduct a pilot randomized controlled trial (RCT) with low-income, suicidal African American women and men that compares the relative effectiveness of compassion meditation (CM) versus a support…
- Trial name
- NCT03463980
- Testing
- Compassion meditation (CM), Support group (SG)
- Where
- United States
- Volunteers
- 456 people
- Sponsor
- Emory University
Suicide Prevention, User Experience
User Evaluation of Zelfmoord1813.be and Its Related Websites
Monitoring the availability and accessibility of suicide prevention information in Flanders remains crucial. In 2022, 1,024 people died by suicide in Flanders, and approximately 10,000 individuals required emergency care…
- Trial name
- NCT07071922
- Testing
- No intervention
- Where
- Belgium
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University Ghent
Suicide, Primary Care
Implementing Suicide Prevention Into Primary Care in Nepal
Suicide remains a major contributor to global mortality, with particularly high and persistent rates in low-resourced settings such as South Asia.
- Trial name
- NCT07362056
- Testing
- Suicide Prevention Package (PSuPP)
- Where
- Nepal
- Volunteers
- 147 people
- Sponsor
- Yale University
Suicide, Depression
Reducing Suicide Risk Among Aging Caregivers of Persons With AD/ADRD
This project aims to adapt, implement, and evaluate a Dialectical Behavior Therapy skills training group intervention for aging adult family caregivers of person with Alzheimer's Disease and Alzheimer's Disease Related Dementias…
- Conditions
- Suicide, Depression, Caregiver Burden, Physical Health
- Trial name
- NCT06055322
- Testing
- Adapted Dialectical Behavior Therapy
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Monopolar Depression, Single Episode or Unspecified, Suicidal and Self-injurious Behaviour
Mindfulness-Based Cognitive Therapy + Safety Planning For Suicidal Behavior
The purpose of this study is to combine and adapt Mindfulness-Based Cognitive Therapy (MBCT) + Safety Planning Intervention (SPI) for individuals with suicidal behavior and to determine its feasibility, acceptability, safety and…
- Trial name
- NCT01826240
- Testing
- MBCT+SPI
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- New York State Psychiatric Institute
Nonsuicidal Self Injury, Nonsuicidal Self-Injury
Psychological Treatment for Adolescents With Self-injury Within Intensive Mental Health Outpatient Services: Randomized Controlled Pilot Trial
The overarching aim of this study is to develop and evaluate a new blended treatment format, which combines face-to-face and digital treatment components, for Emotion Regulation Individual Therapy for Adolescents (ERITA).
- Conditions
- Nonsuicidal Self Injury, Nonsuicidal Self-Injury, Self-Harm
- Trial name
- NCT07755774
- Testing
- Blended ERITA, Treatment as Usual (TAU), Concomitant care
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Psychological Distress, Suicidal Ideation
Development and Testing of imHere4U: A Digital Suicide Prevention Intervention for Cyberbullied Adolescents
The objective of this study is to test the feasibility and preliminary efficacy of Flourish (formerly referred to as imHere4U), a digital suicide prevention intervention for cyberbullied adolescents.
- Trial name
- NCT06002191
- Testing
- Flourish, Questionnaires of Online Experiences
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Pittsburgh
Vitiligo, Depressive Episode
Mental Health Associations With Vitiligo
This cohort study is a large population-based study in the UK to determine the risks of comorbid mental health conditions (including depression, anxiety and other potential psychological complications of vitiligo) in adults with…
- Conditions
- Vitiligo, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders
- Trial name
- NCT04953338
- Testing
- Exposure of mental health condtion of interest
- Where
- United Kingdom
- Volunteers
- 36,104 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Social Functioning, Emotional Distress
Emerging Technologies and Teen Mental Health
This study will recruit teens who are experiencing subacute suicidal ideation to test the effect of a brief psychoeducational intervention focused on social media use wherein youth learn about active and prosocial use of social…
- Conditions
- Social Functioning, Emotional Distress, Suicidal Ideation
- Trial name
- NCT07527052
- Testing
- Prosociality and Agency in Algorithmic Spaces (PAAS) Module
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Florida International University
Suicide, Alcohol Use Disorder
Qungasvik (Toolbox): Prevention of Alcohol/Suicide Risk in Alaska Native Youth
For the past 20+ years the investigators have focused on addressing two interrelated public health issues, alcohol use disorder (AUD) and suicide in Alaska.
- Trial name
- NCT05400135
- Testing
- Qungasvik (Tools for Life)
- Where
- United States
- Volunteers
- 542 people, healthy volunteers welcome
- Sponsor
- University of Alaska Fairbanks
Depression and Suicide
Cognitive Behavioral Therapy Following Esketamine for Major Depression and Suicidal Ideation for Relapse Prevention
This is a rater-blinded, randomized controlled trial. All patients will receive esketamine for treatment of Major Depression with Suicidal Ideation (MDSI).
- Trial name
- ENDURE (NCT04760652)
- Testing
- Cognitive Behavioral Therapy CBT, TAU
- Where
- 3 sites in United States
- Volunteers
- 93 people
- Sponsor
- Yale University
Autism Spectrum Disorder
A Feasibility Study of N-acetylcysteine for Self-injurious Behavior in Children With Autism Spectrum Disorder
The purpose of this study is to demonstrate the feasibility of a 9-week, randomized trial of N-acetylcysteine (NAC) compared to placebo in 14 children (age 5 to 12 years) with Autism Spectrum Disorder (ASD) and a moderate level…
- Trial name
- NAC (NCT03008889)
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Emory University
Suicidal Ideation, Emergency Psychiatric
Treatment of Suicidal Ideation in the Emergency Department Using Nitrous Oxide
Suicide prevention is a major public health concern, with nearly 9,000 suicides and over 200,000 suicide attempts reported each year in France.
- Conditions
- Suicidal Ideation, Emergency Psychiatric, Nitrous Oxide
- Trial name
- PROTORISC (NCT06430489)
- Testing
- Nitrous oxide, Medical air
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Tours
Actual Suicidal Behavior Disorder
Biomarkers of Efficiency of Acceptance and Commitment Therapy in Suicidal Behavior
Suicidal behaviors (SB) are a major health problem in France:10,000 suicides and 220,000 suicide attempts every year. SB management is therefore a major public health issue.
- Trial name
- IMPACT (NCT02936700)
- Testing
- Relaxation, ACT therapy
- Where
- France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Montpellier