Clinical trials: Self Harm
Self-Harm, Suicidal
Co-Producing LGBTQ-Affirmative DBT Protocols.
Aims: 1. To co-produce new intervention parts that meet the needs of LGBTQ+ people at risk of self-harm or suicidal thoughts, with LGBTQ+ people and DBT therapists.
- Conditions
- Self-Harm, Suicidal, Emotional Dysregulation
- Trial name
- NCT06966193
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King's College London
Insomnia, Suicidal Ideation
A Sleep-Oriented Intervention for Suicidal Behaviors
An open-label trial to investigate the use of a behavioral insomnia treatment for suicidal ideation.
- Trial name
- NCT01770587
- Testing
- Behavioral Insomnia Treatment
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Stanford University
Major Depressive Disorder, Major Depressive Episode
The Effects of SAINT® Neuromodulation System on Explicit and Implicit Suicidal Cognition
This multi-site, double-blind, randomized, sham-controlled mechanistic trial aims to test the effects of Magnus Neuromodulation System (MNS) with Stanford Accelerated Intermittent Neuromodulation Therapy (SAINT®) Technology on…
- Conditions
- Major Depressive Disorder, Major Depressive Episode, Suicidal Ideation
- Trial name
- SAINT®SC (NCT03693105)
- Testing
- Active SAINT Stimulation
- Where
- 4 sites in United States
- Volunteers
- 2 people
- Sponsor
- Magnus Medical
Suicide, Suicidal Ideation
Intensive Crisis Intervention
The study's purpose is to improve the clinical management of severe crises experienced by youth with psychiatric disorders by examining a brief, evidence-based alternative to inpatient psychiatric care.
- Conditions
- Suicide, Suicidal Ideation, Suicide, Attempted, Suicide and Self-harm
- Trial name
- ICI (NCT06476886)
- Testing
- Intensive Crisis Intervention (ICI), Adolescent Psychiatric Inpatient Unit (APIU)
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- Jennifer Hughes
Lethal Means Safety, Brief Intervention
Testing Family Firearm Secure Storage Training (FFAST) to Prevent Suicide
Firearms are the lethal means used in over 70% of Veteran suicides with rates of Veteran deaths via self-induced firearm injury rising dramatically (by 64.8%) from 2001 to 2022.
- Conditions
- Lethal Means Safety, Brief Intervention, Concern Significant Others
- Trial name
- FFAST RCT (NCT07692854)
- Testing
- The Family Firearms Secure storage Training (FFAST) Intervention, Health and Stress Counseling
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Substance Misuse, Suicide
A Digital Game Targeting Suicide Prevention in Adolescents Who Report Substance Misuse
The primary aim of this study is to design and develop a digital game that models the process of a safety planning intervention.
- Trial name
- NCT05517382
- Testing
- supportED, Control
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Yale University
Suicide
Evaluation of a Gatekeeper Training Program
The main objective of the proposed study is to evaluate the efficacy of a gatekeeper training suicide intervention program, Applied Suicide Intervention Skills Training (ASIST), in improving medical students' knowledge about…
- Trial name
- NCT01252927
- Testing
- ASIST
- Where
- Canada
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Depressive Disorder, Suicide, Attempted
Brain Markers of Suicide Risk and Psychological Pain in Elderly Depressed Patients
The main objective of this study is to show MRI functional and structural differences between depressed elderly patients with a history of attempted suicide compared to depressed elderly patients with no history of attempted…
- Trial name
- SPAD-IRM (NCT03287986)
- Testing
- MRI
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Suicidal, Suicidal Ideation
Intramuscular Ketamine for Suicidal Patients in the Evanston Hospital Emergency Department for Suicidal Distress
This pilot study aims to evaluate the feasibility and acceptability of administering intramuscular ketamine for the acute reduction of suicidal distress during psychiatric boarding at the Evanston Hospital ED.
- Conditions
- Suicidal, Suicidal Ideation, Suicidal Ideation and Behavior, Depression / Major Depressive Disorder
- Trial name
- KEDS-C (NCT07810023)
- Testing
- Ketamine (0.5 mg/kg)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Endeavor Health
Distress; Maternal, Self Efficacy
Integrated Intervention for Caregivers--Pilot RCT
Adolescents who have been hospitalized for suicidal behavior are at risk for engaging in additional suicidal behavior. After hospitalization, parents or guardians are typically asked to be responsible for helping to prevent…
- Conditions
- Distress; Maternal, Self Efficacy, Parenting, Suicide
- Trial name
- NCT03487627
- Testing
- Electronic and Care Support Manager Contact, Enhanced Treatment-as-usual (TAU)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Wake Forest University Health Sciences
Suicide Attempt
Suicide Prevention Algorithm in the French Overseas Territories
In France, suicide behaviours are a major public health concern that triggered the creation in 2013 of a National Observatory of Suicide.
- Trial name
- APSOM (NCT03427190)
- Testing
- APSOM vs Control
- Where
- 9 sites in French Guiana, Guadeloupe and 2 more
- Volunteers
- 259 people
- Sponsor
- University Hospital Center of Martinique
Borderline Personality Disorder, Self-Injurious Behavior
N-Acetylcysteine in Adjunct to DBT for the Treatment of Self-Injurious Behavior in BPD
Self-Injurious Behavior (SIB) is a dangerous and common symptom in Borderline Personality Disorder (BPD) patients. Approximately 70% of patients with BPD engage in SIB at some point, compared to 17.5% of patients with other…
- Trial name
- NCT00539188
- Testing
- N-Acetylcysteine
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Yale University
Covid19, Mental Health
Mental Health Among Patients, Providers, and Staff During the COVID-19 Era
The Mental Health Among Patients, Providers, and Staff (MHAPPS) Study is designed to study how the COVID-19 pandemic has affected mental health and wellbeing, and how to support mental health while minimizing the burden on the…
- Trial name
- MHAPPS (NCT04700137)
- Testing
- Caring Contacts Plus Introductory Phone Call (CC+), Caring Contacts without an introductory phone call (CC)
- Where
- United States
- Volunteers
- 666 people
- Sponsor
- St. Luke's Health System, Boise, Idaho
Suicidality, COVID -19
Analysis of Suicidal Behavior Among Children and Adolescents in the Auvergne-Rhone-Alpes Region During the Covid 19 Pandemic Period
In 2020, the world is hit by a global health crisis due to a pandemic following the appearance of Sars-cov-2 or "covid-19". This pandemic was accompanied by a constant fear of contamination and death, relayed by the media.
- Trial name
- TSPedCovid (NCT07302295)
- Testing
- Aggregated data collection, Data collection and qualitative interview
- Where
- 4 sites in France
- Volunteers
- 6,500 people
- Sponsor
- Hospices Civils de Lyon
Post Traumatic Stress Disorder, Cannabis Use
Warrior CARE: Cannabis Behavioral Health
This study is a randomized, controlled clinical trial to examine the therapeutic potential of cannabinoids for treating veterans with PTSD and suicidal ideation.
- Conditions
- Post Traumatic Stress Disorder, Cannabis Use, Suicide, Veterans
- Trial name
- CBH (NCT06381180)
- Testing
- Tetrahydrocannabinol, Cannabidiol
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Wayne State University
Major Depressive Disorder With Suicidal Ideation With Intent
Study of Efficacy and Safety of MIJ821 in Addition to Comprehensive Standard of Care on the Rapid Reduction of Symptoms of Major Depressive Disorder in Subjects Who Have Suicidal Ideation With Intent
Study of efficacy and safety of MIJ821 in addition to comprehensive standard of care on the rapid reduction of symptoms of Major Depressive Disorder (MDD) in subjects who have suicidal ideation with intent
- Trial name
- NCT04722666
- Testing
- MIJ821 Intravenous Injection
- Where
- 39 sites in United States, Argentina and 12 more
- Volunteers
- 199 people
- Sponsor
- Novartis Pharmaceuticals
Caregivers, Decision Making
"Safety in Dementia": An Online Caregiver Intervention
In an online randomized trial of Safety in Dementia with national recruitment and longitudinal follow-up, we will recruit informal caregivers of community-dwelling adults with dementia who have firearm access.
- Conditions
- Caregivers, Decision Making, Alzheimer Disease, Social Media
- Trial name
- NCT05173922
- Testing
- Safety in Dementia
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Anxiety, Suicide
Computerized Anxiety Treatment for Suicide
The purpose of this study is to test the effectiveness and usability of multiple computer-based treatments for mood and anxiety relevant risk factors.
- Trial name
- CATS (NCT01990131)
- Testing
- Cognitive Anxiety Sensitivity Treatment, Physical Health Education Training
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Florida State University
Suicide, Suicidal Ideation
Brief Interventions for Short-Term Suicide Risk Reduction in Military Populations
The purpose of the proposed study is to identify the most effective brief interventions for reducing short-term risk for suicide attempts in "real world" military triage settings, and to identify potential mechanisms of change…
- Trial name
- BISSR (NCT02042131)
- Testing
- Treatment As Usual (TAU), Standard Crisis Response Plan (S-CRP), Enhanced Crisis Response Plan (E-CRP)
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- University of Utah
Suicide
Culturally Centered CBT for Latinx Youth
The primary aim of the proposed research is to test the effect of a culturally centered treatment protocol, the Socio-cognitive behavioral therapy (SCBT), versus Treatment as Usual on suicidal thoughts and attempts, and…
- Trial name
- NCT04278157
- Testing
- Socio-Cognitive Behavioral Therapy for Suicidal Behavior (SCBT-SB), Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 114 people
- Sponsor
- Bradley Hospital