Clinical trials: Sedation
Anesthesia for Urologic Endoscopic Surgery, Urinary Calculi
Fospropofol Disodium Versus Propofol for Patient Satisfaction in Ureteroscopy
This single-center single-blind randomized trial compares fospropofol disodium and propofol for anesthesia in elective ureteroscopy patients.
- Trial name
- NCT07659132
- Testing
- Fospropofol disodium plus sufentanil for anesthesia induction, Propofol plus sufentanil for anesthesia induction
- Volunteers
- 190 people
- Sponsor
- Shiyou Wei
Profound Mental Retardation
Radiological Examination of the Mentally Handicapped Patients
Aim of this study is to evaluate the necessity of the radiological examinations of mentally handicapped or uncooperative patients.
- Trial name
- NCT02741011
- Testing
- Radiological examination
- Volunteers
- 98 people
- Sponsor
- Tokat Gaziosmanpasa University
Patient Satisfaction
Music in Interventional Radiology Procedures
The use of music as medical therapy for the treatment of mental health conditions like depression and anxiety is well established.
- Trial name
- NCT05728398
- Testing
- Music, No Music
- Volunteers
- 60 people
- Sponsor
- Western University, Canada
Bronchoscopy
Narcotrend Versus Bispectral Index Monitoring During Sufentanil-Midazolam Anesthesia for Bronchoscopy
This study was aimed to determine whether narcotrend monitoring was better than bispectral index monitoring during sufentanil-midazolam anesthesia for bronchoscopy under conscious sedation.
- Trial name
- NCT03738137
- Testing
- Narotrend, BIS, Sufentanil
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Guangzhou Institute of Respiratory Disease
Endoscopic Retrograde Cholangiopancreatography, Conscious Sedation Adverse Event
TEAS for Sedation During ERCP: A Multicenter Trial With Mechanistic Substudy
1. The goal of this clinical trial is to learn if transcutaneous electrical acupoint stimulation (TEAS), a non-invasive therapy that applies mild electrical current to specific points on the skin, can help patients undergoing…
- Conditions
- Endoscopic Retrograde Cholangiopancreatography, Conscious Sedation Adverse Event, Procedural Pain, Sedation-related Complications
- Trial name
- TEAS-ERCP-MC (NCT07440342)
- Testing
- TEAS + Conscious Sedation
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Beijing 302 Hospital
Sleep
The Effect of Ketamine on Sleep Quality in Patients Undergoing Colonoscopy
Sedation typically begins with 2 mg of midazolam (0.025-0.1 mg/kg), followed by propofol given initially at 0.5-1.0 mg/kg bolus doses, with additional 0.25-0.5 mg/kg boluses as needed every 1-3 minutes to maintain sedation.
- Trial name
- NCT06498869
- Testing
- Ketamine Hcl 50Mg/Ml Inj
- Where
- Turkey (Türkiye)
- Volunteers
- 178 people
- Sponsor
- Kocaeli City Hospital
Pain, Sedation
A Study to Assess the Analgesia and Sedation Using Intranasal Dexmedetomidine in Third Molar Surgery Under Local Anaesthesia
Dental procedures such as wisdom tooth removal evoke very high levels of patients' anxiety and it is, therefore, common practice to provide concomitant pharmacologic sedation.
- Trial name
- NCT01132794
- Testing
- Intranasal dexmedetomidine
- Where
- Hong Kong
- Sponsor
- The University of Hong Kong
Critical Illness, Mechanical Ventilation
Analysis of Weaning of Analgosedation and Kinetics of Emergence in Critically Ill Patients
The goal of this prospective multicenter observational study is to characterize early trajectories of consciousness recovery following the first valid structured awakening trial in mechanically ventilated critically ill adults, a…
- Conditions
- Critical Illness, Mechanical Ventilation, Weaning Invasive Mechanical Ventilation, Sedation and Analgesia
- Trial name
- AWAKE-ICU (NCT07710066)
- Testing
- Structured Awakening Evaluation (SAE)
- Volunteers
- 500 people
- Sponsor
- Patricia Rodriguez Villamizar
Ketamine, Propofol
Ketamine Versus Propofol as ICU Sedation
this study is to assess the hemodynamic profile of ketamine compared with propofol in critically ill, mechanically ventilated adult Patients study will be carried out on 100 mechanically ventilated patients who received one…
- Conditions
- Ketamine, Propofol, Sedation, Mechanical Ventilation
- Trial name
- NCT06243822
- Testing
- Ketamine, Propofol
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Menoufia University
Abdominal Pain
Carbon Dioxide Insufflation Versus Conventional Air Insufflation
The safety and effectiveness of esophagogastroduodenoscopy and colonoscopy in the detection of gastrointestinal-tract pathology in children has been established during the last three decades.
- Trial name
- NCT02790359
- Testing
- Air, Carbon dioxide
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Medical College of Wisconsin
Mechanical Ventilation, Sedation
Implementation of an Analgesia-sedation Algorithm in the Pediatric ICU to Reduce Benzodiazepine Use
The purpose of the study is to develop and implement an evidence-based analgesia-sedation algorithm in the pediatric intensive care unit (PICU) using quality improvement and implementation science methodology.
- Trial name
- NCT04263662
- Testing
- Analgesia-Sedation algorithm
- Where
- United States
- Volunteers
- 680 people
- Sponsor
- Boston Children's Hospital
Acute Stroke
SEACOAST 1- SEdAtion With COllAteral Support in Endovascular Therapy for Acute Ischemic Stroke
SEACOAST 1 is a prospective, randomized, blinded endpoint trial comparing collateral vigor and clinical outcomes, with different forms of GA in patients with acute ischemic stroke due to anterior circulation large vessel…
- Trial name
- SEACOAST (NCT03737786)
- Testing
- Tight control of end-tidal CO2 levels
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of California, Los Angeles
Sedation
Sedation MRI - Propofol Versus Propofol-Ketamin in Children
Children < 10 years of age often need deep sedation or anaesthesia to allow elective diagnostic magnetic resonance imaging; standard routine protocols are 1.
- Trial name
- NCT01519154
- Testing
- Propofol, Ketamine-Propofol
- Where
- Switzerland
- Volunteers
- 347 people
- Sponsor
- Achim Schmitz
Sedation
Evaluation of Sedation in Newborns
Neonates treated on Neonatal Intensive Care Units are often critically ill, subject to numerous painful procedures and often dependent on mechanical ventilation.
- Trial name
- NCT01265186
- Testing
- Bispectral Index, Amplitude-integrated EEG
- Where
- Austria
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Pediatric Sedation
Lullaby vs White Noise vs Silence in Pediatric MRI Sedation
This prospective randomized study aims to evaluate the effects of three auditory conditions-lullaby music, white noise, and silent headphone use-on sedation depth, anesthetic drug requirements, and recovery outcomes in children…
- Trial name
- CALMMRI (NCT07325331)
- Testing
- Silent Headphone, White Noise, Lullaby Music
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Medically Assisted Procreation (MAP), Oocyte Retrieval
Monocentric Randomised Controlled Trial to Assess Whether Virtual Reality Reduces the Use of Hypnotic Agents During IVF/ICSI Oocyte Retrieval
Over the last few years, audiovisual distraction devices using animation, films and 3D immersion have been developed, with the aim to provide patients with a relaxing experience that disconnects them from the operating…
- Trial name
- REVAHPOVO (NCT07190729)
- Testing
- Propofol sedation + Audiovisual distraction, Propofol sedation
- Where
- France
- Volunteers
- 52 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
Anxiety, Biliary and Pancreatic Diseases
Effect of Patient Anxiety Level Prior to Undergoing ERCP and Procedure Tolerability and Outcomes.
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a specialized procedure combining upper GI endoscopy and x-rays to treat hepatopancreaticobiliary diseases. Patient experiences after ERCP has been relatively understudied.
- Conditions
- Anxiety, Biliary and Pancreatic Diseases, ERCP
- Trial name
- NCT07699731
- Testing
- Not applicable- observational study
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Mandip Rai
Abdominal Aortic Aneurysm, Acute Kidney Injury
Dexmedetomidine vs Propofol Sedation in Endovascular Aortic Repair
Endovascular aortic repair (EVAR) is increasingly performed under local anesthesia with intravenous sedation, but the optimal sedative agent has not been established.
- Trial name
- NCT07857005
- Testing
- Dexmedetomidine, propofol
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 282 people
- Sponsor
- Bursa City Hospital
Psychomotor Agitation, Psychiatric Disorder
Randomised Trial Ketiapine Olanzapine Fast Sedation Agitated Patients Emergency Ward
comparison of intramuscular olanzapine and ketamine efficacy as first medication for fast sedation of patients with agitation and aggressive behavior.
- Conditions
- Psychomotor Agitation, Psychiatric Disorder, Emergency Psychiatric, Tranquilizers
- Trial name
- IM-OK-FAST (NCT03216941)
- Testing
- Ketamine
- Where
- Argentina
- Volunteers
- 500 people
- Sponsor
- Universidad Nacional de Rosario
Traumatic Brain Injury, Delirium
Comparison of Haloperidol and Dexmedetomidine for Delirium and Agitation in ICU Patients With Traumatic Brain Injury
Traumatic brain injury is a serious and common medical condition that often requires admission to the intensive care unit and the use of mechanical ventilation.
- Conditions
- Traumatic Brain Injury, Delirium, Agitation
- Trial name
- NCT06993194
- Testing
- Haloperidol, Dexmedetomidine
- Volunteers
- 40 people
- Sponsor
- Benha University