Clinical trials: Scoliosis Correction
Asses Radiological Efficacy of Posterior Approach Regarding Correction of Cobb Angle Post Operative . • Asses, Scoliosis Idiopathic Adolescent Treatment
Surgical Outcomes and Complications of Posterior Spinal Fusion in Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is the most common form of scoliosis representing about 80-90% of all idiopathic scoliosis cases , characterized by lateral curvature of the spine of 10 degrees or more in children 10-18…
- Trial name
- Scoliosis (NCT07092917)
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Assiut University
Adolescent Idiopathic Scoliosis, Juvenile Idiopathic Scoliosis
IV Methadone Vs EXPAREL Erector Spinae Plane Blockade in Pediatric Subjects Undergoing Idiopathic Scoliosis Correction
The goal of this pilot study is to assess the feasibility of conducting a randomized controlled trial at a single institution comparing erector spinae plane blockade (ESPB) with liposomal bupivacaine (LB, Exparel) to intravenous…
- Trial name
- AIMS (NCT05730920)
- Testing
- Methadone, Liposomal bupivacaine (LB, Exparel)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Dr. Casey Stondell, MD
Idiopathic Scoliosis
Scoliosis Surgery Using the PASS® LP System
The purpose of this study is to find out the outcomes of using the PASS LP System to correct idiopathic scoliosis. This system is a unique set of spinal instrumentation used to surgically correct the rotation and deformity of the…
- Trial name
- NCT01019109
- Testing
- Posterior Spinal Fusion Device: Titanium rod arm used titanium rods, and CoCr rod arm used Cobalt Chrome rods as a part of the construct.
- Where
- 3 sites in United States
- Volunteers
- 79 people
- Sponsor
- Medicrea, USA Corp.
Scoliosis; Adolescence, Pain After Surgery
Tegileridine for Postoperative Pain After Adolescent Scoliosis Surgery
The goal of this clinical trial is to see if a new pain medicine called Tegileridine is at least as effective as morphine (the standard treatment) for pain relief after spinal surgery in teenagers with scoliosis.
- Conditions
- Scoliosis; Adolescence, Pain After Surgery, Analgesia, Patient-controlled
- Trial name
- NCT07229495
- Testing
- Tegileridine, morphine
- Where
- 6 sites in China
- Volunteers
- 171 people
- Sponsor
- Peking Union Medical College Hospital
Idiopathic Scoliosis
REFLECT Scoliosis System Post Approval Study
The purpose of this multi-center, prospective, single-arm registry Post-Approval Study (PAS) is to evaluate the radiographic and clinical outcomes of 100 patients with idiopathic scoliosis treated with the REFLECT™ Scoliosis…
- Trial name
- NCT06298812
- Testing
- REFLECT Scoliosis Correction System
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Globus Medical Inc
Scoliosis Correction, Esketamine
Different Dose Esketamine and Dexmedetomidine Combination for Supplemental Analgesia After Scoliosis Correction Surgery
Scoliosis correction surgery is associated with severe pain. Patients after scoliosis correction surgery usually require high dose opioids and long duration analgesia, which may increase side effects and drug tolerance.
- Conditions
- Scoliosis Correction, Esketamine, Dexmedetomidine, Postoperative Analgesia
- Trial name
- NCT06062550
- Testing
- Esketamine
- Where
- China
- Volunteers
- 312 people
- Sponsor
- Peking University First Hospital
Scoliosis
Phase IV Comparing Rods of Yield Strengths to Correct Adolescent Idiopathic Scoliosis.
There has been a growing trend amongst surgeons to use a construct for correction of scoliosis which involves segmental instrumentation with pedicle screws.
- Trial name
- NCT00768313
- Testing
- titanium rod, ultra strength stainless steel rod
- Where
- Canada
- Sponsor
- Queen's University
Scoliosis Correction, Postoperative Analgesia
Different Dose Esketamine and Dexmedetomidine for Supplemental Analgesia and Longterm Outcomes
Chronic postsurgical pain (CPSP) refers to pain that occurs or increases after surgery and lasts longer than 3 months. Severe acute postoperative pain is one of the major risk factors of CPSP.
- Conditions
- Scoliosis Correction, Postoperative Analgesia, Esketamine, Dexmedetomidine
- Trial name
- NCT06087510
- Testing
- Esketamine
- Where
- China
- Volunteers
- 312 people
- Sponsor
- Peking University First Hospital
Postural Alignment, Idiopathic Adolescent Scoliosis
Artificial Intelligence-Based Postural Feedback for Scoliosis
Due to advancements in technology, Posture-Analyzing and Virtual Reconstructing (PAViR) systems were developed. They used Red-Green-Blue-Depth camera sensors and artificial intelligence to evaluate human posture alignment, muscle…
- Trial name
- NCT07669428
- Testing
- Postural feedback, Physical therapy for scoliosis
- Where
- Thailand
- Volunteers
- 30 people
- Sponsor
- Mahidol University
Idiopathic Scoliosis
Scoliosis-specific Exercises for Mild Idiopathic Scoliosis
Idiopathic scoliosis is the most common spinal deformity in children and adolescents with an estimated prevalence of 3%. About one tenth of the children with scoliosis develop a deformity that requires treatment with brace or…
- Trial name
- NCT05138393
- Testing
- Active self-corrective exercises, Observation
- Where
- 2 sites in Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet
Cases of Early Onset Scoliosis
Management of Early Onset Scoliosis by Active Apex Correction Technique
Early onset scoliosis is challenging cases in management .different techniques used to correct the deformity ranging between fusionlees and fusion surgery.
- Trial name
- NCT07727408
- Testing
- Active Apex correction of scoliotic deformity
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Retrolaminar Block, Analgesia
Ultrasound Guided Bilateral Retrolaminar Block as Analgesia for Adolescent Idiopathic Scoliosis Correction
Scoliosis is a structural, tridimensional deformity of the spine. Characterized by lateral curvature and rotation of the vertebrae with functional limitations and cosmetic problems, idiopathic scoliosis, which accounts for 75% to…
- Conditions
- Retrolaminar Block, Analgesia, Adolescent, Idiopathic Scoliosis
- Trial name
- NCT04336111
- Testing
- retrolaminar block
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Tanta University
Adolescent Idiopathic Scoliosis
Ergonomic Brace Wear for Adolescent Idiopathic Scoliosis
This study assesses the effectiveness of a new scoliosis brace design for adolescent idiopathic scoliosis (AIS) patients, named Ergonomic Brace, by comparing the outcome with hard brace in terms of three aspects: 1.
- Trial name
- NCT03617120
- Testing
- Ergonomic Brace vs hard brace
- Where
- Hong Kong
- Volunteers
- 15 people
- Sponsor
- The Hong Kong Polytechnic University
Scoliosis; Adolescence
O-arm Assessment of Vertebral Movement Using ST2R Technique
The study is quantifying how the patients' back has been corrected using Medicrea's hardware through imaging taken before,during and after the surgery.
- Trial name
- NCT03609138
- Testing
- Spinal Hardware
- Sponsor
- Medicrea, USA Corp.
Adolescent Idiopathic Scoliosis (AIS), Ealy Onset Scoliosis
Development of a Conservative Care and Bracing Registry (CCBR)
Idiopathic scoliosis (IS) is a common problem affecting approximately 3% of the population; its progression can lead to significant health problems.
- Conditions
- Adolescent Idiopathic Scoliosis (AIS), Ealy Onset Scoliosis, Juvenile Idiopathic Scoliosis, Infantile Idiopathic Scoliosis
- Trial name
- CCBR (NCT07527611)
- Where
- United States
- Volunteers
- 280 people
- Sponsor
- National Scoliosis Center
Adult Spinal Deformity
Neurologic Complications in Spinal Deformity Surgery
240 subjects with "high risk" adult spinal deformity requiring surgical correction will be enrolled in a prospective multi-center international study.
- Trial name
- NCT01305343
- Testing
- Routinely performed surgical correction of spinal deformity
- Where
- 15 sites in United States, Canada and 5 more
- Volunteers
- 273 people
- Sponsor
- AO Foundation, AO Spine
Idiopathic Scoliosis
Effects of Real-Time Feedback Assisted Self-Correction on the Posture of Scoliotic Patients
Scoliosis is a progressive three-dimensional deformation of the spine during growth, with a prevalence of 80% in girls. The treatments currently used are surgery and rigid brace, which aim to stabilize scoliosis evolution.
- Trial name
- COVIRSCOL (NCT03978273)
- Testing
- Night-time brace + virtual-brace, Night-time brace only
- Where
- France
- Volunteers
- 74 people
- Sponsor
- University Hospital, Grenoble
Scoliosis
Curve Correction of Early Onset Scoliosis by Mehta Serial Casts
Assessment of the role of Mehta Serial Casts in Curve Correction of Early Onset Scoliosis
- Trial name
- NCT06277089
- Testing
- Casts
- Volunteers
- 5 people
- Sponsor
- Assiut University
Adolescent Idiopathic Scoliosis
MRI-Guided Dynamic Support System for Scoliosis Correction
This prospective pilot study evaluates the feasibility and effectiveness of an MRI-guided dynamic support system (MRI-DSS) for rapid, quantitative correction of adolescent idiopathic scoliosis (AIS).
- Trial name
- NCT07246122
- Testing
- MRI-guided Dynamic Support System
- Where
- Hong Kong
- Volunteers
- 10 people
- Sponsor
- Chinese University of Hong Kong
Scoliosis Correction, Iron Deficiency
IntraVenous Iron in Kids With Iron Deficiency and Scoliosis Study
Adolescents and young adults undergoing spinal fusion surgery for the correction of scoliosis and other spinal deformity are at high risk of perioperative iron deficiency and anemia, yet the means and evidence for optimizing iron…
- Conditions
- Scoliosis Correction, Iron Deficiency, Transfusion Blood, Surgery Complications
- Trial name
- IV-KIDS (NCT07217873)
- Testing
- Ferric carboxymaltose IV
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Columbia University