Clinical trials: Sciatica
Low Back Pain, Sciatica
Effect of Sciatic Nerve Slider Technique in Different Positions in Low Back Pain Patients
Neural mobilization is a technique that plays an important role in repairing the neural tissue's ability to respond to stress or tension by triggering the reconstruction of normal physiological functioning, pain reduction, and…
- Trial name
- NCT05907356
- Testing
- sciatic nerve slider technique in slump lying position, sciatic nerve slider technique in supine position, Conventional physiotherapy
- Where
- Palestinian Territories
- Volunteers
- 60 people
- Sponsor
- European University of Lefke
Sciatica, Radiating Pain
The Effect of Early MSAT Treatment on Sciatica Caused by Traffic Accidents.
The investigators would like to conduct a pilot study prior to a practical randomized control study on the effectiveness of initial MSAT treatment on inpatients complaining of radiating pain and abnormal sensation in the lower…
- Conditions
- Sciatica, Radiating Pain, Paresthesia, Dysesthesia
- Trial name
- NCT06179901
- Testing
- Integrative Korean Medicine Treatment, lower limb motion style acupuncture treatment
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Jaseng Medical Foundation
Sciatica, Lumbar Radiculopathy
Brain Mechanisms Supporting Cannabis-induced Pain Relief
Chronic low back pain is a common and disabling condition that affects millions of people in the United States. Many people with chronic low back pain do not get enough relief from current treatments.
- Conditions
- Sciatica, Lumbar Radiculopathy, Lower Back Pain, Degenerative Disc Disease
- Trial name
- NCT04982965
- Testing
- Active Cannabis
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Sciatica
Effects of Pilates Exercises and Neural Dynamic Mobilization in Sciatica Patients
The main purpose of the study is to find the effects of Pilates exercises and neural mobilization techniques on pain, flexibility and quality of life in sciatica patients.
- Trial name
- NCT05959317
- Testing
- Pilates Exercises, Neural dynamic mobilization
- Where
- 2 sites in Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Lumbar Radiculopathy, Lumbar Disc Herniation
Randomized Evaluation of Lumbar Injection Effectiveness and Function
The goal of this clinical trial is to learn whether the Triojection® System is safe and effective for treating symptomatic lumbar radiculopathy (leg pain caused by nerve irritation or compression) resulting from a contained…
- Conditions
- Lumbar Radiculopathy, Lumbar Disc Herniation, Contained Herniated Lumbar Disc
- Trial name
- RELIEF (NCT07856810)
- Testing
- Triojection® System, Selective Nerve Root Block (SNRB)
- Volunteers
- 300 people
- Sponsor
- SpinaFX Medical Inc.
Lumbosacral Radiculopathy
Does Magnetic Resonance Imaging (MRI) Improve Interventional Outcomes for Lumbosacral Radiculopathy?
Epidural steroid injections (ESI) are the most frequently performed procedures in pain clinics. When performing ESI, there is no consensus about how to best select candidates for this intervention, and which level(s) to inject.
- Trial name
- NCT00826124
- Testing
- Epidural steroid injection, Magnetic Resonance Imaging (MRI)
- Where
- 2 sites in United States
- Volunteers
- 131 people
- Sponsor
- Johns Hopkins University
Sciatica Acute
Comparing Ultrasound-Guided Transgluteal Nerve Block to Standard Care
The goal of this clinical trial is to compare transgluteal sciatic nerve block to standard of care to treat sciatic back pain in adult patients who present to the emergency department.
- Trial name
- TGSNB vs SoC (NCT07397117)
- Testing
- nerve block with ropivacaine, Standard medical treatment
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Sciatica, Intervertebral Disc Disorder
Alternative and Integrative Therapy for Lumbar Disk Herniation
The investigators report management of lumbar disc herniation with severe sciatic pain using an integrative complementary and alternative medicine approach with a 5 year follow-up.
- Trial name
- NCT01989403
- Testing
- herbal medicine, acupuncture, bee-venom acupuncture, and Chuna manipulation
- Where
- South Korea
- Volunteers
- 128 people
- Sponsor
- Jaseng Hospital of Korean Medicine
Lumbar Osteoarthritis
Primary Osteoarthritis Lumbar Spine: Establishing Its Cause, Pathogenesis and Treatment.
The study was about a root cause of Primary Osteoarthritis Lumbar Spine producing disabilities in sitting, climbing and walking etc. In advance stage the person is bereft of his/her personal physical activities.
- Trial name
- NCT05693415
- Where
- 6 sites in India
- Volunteers
- 154 people
- Sponsor
- Knee Pain Clinic
Lumbar Disc Herniation, Lumbar Radiculopathy
Selective Nerve Root Block Versus Sham to Reduce Surgery for Lumbar Disc Herniation
The SELDISC trial will investigate whether a selective nerve root block can reduce the need for surgery in adults with a herniated disc in the lower back.
- Conditions
- Lumbar Disc Herniation, Lumbar Radiculopathy, Lumbar Disc Herniation With Radiculopathy
- Trial name
- SELDISC (NCT07895589)
- Testing
- Selective Nerve Root Block
- Where
- 2 sites in Sweden
- Volunteers
- 262 people
- Sponsor
- Karolinska Institutet
Piriformis Syndrome
Interfascial Hydrodissection Added to Ultrasound-Guided Piriformis Injection for Piriformis Syndrome
The gluteus maximus overlies the piriformis muscle and forms a broad fascial interface with it. Restricted movement, increased tension, or adhesions between these tissue layers may contribute to persistent buttock pain in…
- Trial name
- NCT07813455
- Testing
- Ultrasound-Guided Piriformis Injection, Ultrasound-Guided Interfascial Hydrodissection, Standardized Home-Based Piriformis Stretching Program
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Lumbar Radiculopathy, Sciatica
Dose Dependent Steroid Injections
This study aims to evaluate the efficacy of interlaminar steroid injections at treating pain in lumbar radiculopathy at varying doses, to evaluate the efficacy of interlaminar steroid injections at improving quality of life and…
- Conditions
- Lumbar Radiculopathy, Sciatica, Back Pain With Radiation
- Trial name
- NCT07494136
- Testing
- Triamcinolone 10 Mg/mL Injectable Suspension, Triamcinolone 40 Mg/mL Injectable Suspension, Triamcinolone 80 Mg/mL Injectable Suspension
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Miami
Radiculopathy, Radiculopathy Lumbar
Mirror Image Spine Correction Exercises Versus Conservative Physiotherapy for Lumbar Radiculopathy
Lumbar radiculopathy is a common condition caused by irritation or compression of a lumbar nerve root, often resulting in radiating leg pain, numbness, weakness, and functional limitation.
- Conditions
- Radiculopathy, Radiculopathy Lumbar, Sciatica, Disc Disease Lumbar
- Trial name
- MIRROR-LR (NCT07558993)
- Testing
- Mirror Image Spine Correction Exercises, Conservative Physiotherapy
- Where
- United Arab Emirates
- Volunteers
- 64 people
- Sponsor
- University of Sharjah
Low Back Pain, Low Back Pain, Mechanical
Effects of Acupuncture on the Radial Pressure Pulse-wave at Cunkou in Low Back Pain
Introduction: In TCM, Pulse Diagnosis has been one of the key diagnostic components in the clinical examinations. Traditionally, the palpation of the pulse on the radial artery is subjective among the physicians.
- Conditions
- Low Back Pain, Low Back Pain, Mechanical, Low Back Pain, Recurrent, Low Back Pain, Postural
- Trial name
- NCT03501771
- Testing
- Acupuncture
- Where
- Taiwan
- Volunteers
- 42 people
- Sponsor
- China Medical University Hospital
Radiculopathy Lumbar, Disk Herniated Lumbar
Position-Induced Opening of the Intervertebral Foramen is Efficient to Treat an Acute Lumbosacral Radiculopathy Caused by Disc Herniation
Efficiency of the conservative mechanical lumbosacral nerve root decompression, as an adjunct to pharmacological treatment, in the case of acute lumbosacral radiculopathy.
- Conditions
- Radiculopathy Lumbar, Disk Herniated Lumbar, Low Back Pain
- Trial name
- NCT04276519
- Testing
- Physiotherapeutic, non-invasive position-induced opening of the intervertebral foramen
- Volunteers
- 20 people
- Sponsor
- General Hospital Sveti Duh
Sciatica
Effectiveness of Combined Neural Mobilization With Manual Myofascial Release for Sciatic Pain Relief
This study will address to evaluate and compare both Neural mobilization and Manual Myofascial Release of piriformis and Lumbar muscles in sciatic pain with the aim of evaluating and identifying the most effective intervention…
- Trial name
- NCT06947785
- Testing
- Combined Neural Mobilization with Manual myofascial Release, Neural Mobilization, Manual Myofascial Release
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Sciatica, Discogenic Pain
Neurodynamic Moblization Versus Mulligan on Pain and Functional Abilities in Patients With Chronic Discogenic Sciatica
The purpose of the present study to compare between the effect of neurodynamic moblizaton and Mulligan SNAG's moblization on patients with chronic unilateral discogenic sciatica.
- Trial name
- DS (NCT07050108)
- Testing
- neurodynamic mobilization, mulligan therapy, selected physical therapy program
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Cairo University
Sciatica
Adalimumab in Severe and Acute Sciatica
The purpose of this study is to determine whether adalimumab (a TNF-alpha inhibitor) is effective in the treatment of severe and acute sciatica.
- Trial name
- ASAS (NCT00470509)
- Testing
- Adalimumab
- Where
- Switzerland
- Volunteers
- 61 people
- Sponsor
- University Hospital, Geneva
Low Back Pain, Sciatica
BOL-DP-o-04 in Patients With Low Back Pain and Sciatica
The study is aimed to evaluate the pain-relieving effect of BOL-DP-o-04, in addition to SOC, on Low Back Pain and Sciatica.
- Trial name
- NCT04145310
- Testing
- BOL-DP-o-04 + SCO
- Where
- Israel
- Volunteers
- 26 people
- Sponsor
- Breath of Life International Pharma Ltd
Pain
A Pilot Study of Switching From One Pain Medication to Another (Opioid Rotation)
The purpose of this study is to see if changing from one pain medication like morphine or oxycodone to another pain medication, oxymorphone (OPANA®), will be helpful to patients.
- Trial name
- NCT00580294
- Testing
- Oxymorphone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Icahn School of Medicine at Mount Sinai