Clinical trials: Scar
Wound Heal, Cesarean Section Complications
The Effect of Suturing Material on Scar Healing
We want to compare the effects of 2 suture materials (monofilament and multifilament) on healing of the uterine scar after a cesarean delivery.
- Conditions
- Wound Heal, Cesarean Section Complications, Cesarean Wound Disruption, Suture Related Complication
- Trial name
- NCT03968783
- Testing
- Monofilament suture, Multifilament suture
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Endometriosis, Adhesion
New Cross Linked Hyaluronan Gel After Deep Infiltrating Endometriosis Surgery
Hyaluronan, a glycosaminoglycan found in connective tissues and extracellular matrix, has been postulated to reduce postoperative adhesions, because of its unconditioned biological functions at tissue repair but unfortunately it…
- Conditions
- Endometriosis, Adhesion, Quality of Life, Surgery
- Trial name
- HYALOENDOQoL (NCT04023383)
- Testing
- 40 cc HyaRegen NCH gel, 40 cc sterile saline solution
- Volunteers
- 60 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Gynecologic Disease, Cosmesis
Comparison of Cosmesis, Patient Satisfaction and Quality of Life in Patients Undergoing Laparoscopic Surgery
To compare robot assisted versus conventional laparoscopic surgery performed for bening gynecologic disorders regarding cosmesis, patient satisfaction and quality of life
- Conditions
- Gynecologic Disease, Cosmesis, Patient Satisfaction, Quality of Life
- Trial name
- NCT04064216
- Testing
- Laparoscopic surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Hypertrophic Scar
A Study to Evaluate the Safety, Tolerability and Efficacy of AK3280 Cream on Hypertrophic Scar
A randomized, double-blind, placebo self-controlled phase I/II clinical study to evaluate the safety, tolerability and preventive efficacy of different doses of AK3280 cream （AK3287 ） after cicatrectomy in Patients with…
- Trial name
- NCT05434897
- Testing
- AK3280 Cream
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Ark Biopharmaceutical Co., Ltd.
Uveal Melanoma, Melanoma, Uveal
Endoresection of the Tumor Scar or Transpupillary Thermotherapy for the Treatment of Large Uveal Melanomas (Endoresection-Laser)
Study the efficacy of endoresection of the tumor scar or, when surgery is not possible, transpupillary thermotherapy on the tumor scar to prevent neovascular glaucoma and secondary enucleation
- Trial name
- NCT02874040
- Testing
- Endoresection, Laser diode
- Where
- France
- Volunteers
- 87 people
- Sponsor
- Institut Curie
Acne Scars
A Pilot Study Testing the Efficacy of a Needling Device for the Treatment of Acne Scars
The primary objective of this study is to determine the efficacy of a needling device for treatment of acne scars.
- Trial name
- NCT00974870
- Testing
- needling treatment
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Dupuytren Contracture
The Effects of Prophylactic Limited Palmar Fasciectomy on Surgical Outcomes and Scarring
Research is instrumental for improving medical care and the patient experience. Finding new surgical techniques can create better outcomes and minimize recovery time and complications for patients.
- Trial name
- NCT03155854
- Testing
- Pretendinous cord excision, Division/manipulation of the cord
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Infertility, Complications; Cesarean Section
Does Cesarean Section Scar Defect (Niche) Affect Implantation Rate?
Cesarean scar defects (CSDs), i.e. deficient uterine scars following a cesarean section, involve discontinuity at the site of a previous Cesarean section scar.
- Trial name
- NCT02371486
- Testing
- hysteroscopic repair of cesarean section defect, Diagnostic Hysteroscopy, Ultrasound Scan
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Sheba Medical Center
Hypertrophic Scars
Treatment of Hypertrophic Scars Using Fractional CO2 Laser Alone in Comparison With Adding Botulinum Toxin Either Through Intralesional Injection or Assisted Drug Delivery
The current study aimed to evaluate the effectiveness of fractional laser treatment alone and fractional laser combined with botulinum toxin A, delivered either through injections or topical application fractional laser-assisted…
- Trial name
- BTX and LADD (NCT07360483)
- Testing
- Botulinum toxin type A (Botox®, Allergan)
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Cairo University
Premenopausal HR+/HER2- Metastatic Breast Cancer
PALbociclib Endocrine Therapy Followed by Talazo Vs. Talazoz-Atezo Study
This study is a prospective, two-arm, randomized phase II study of talazoparib versus talazoparib plus atezolizumab in ER+ premeonopausal women with metastatic breast cancer harboring HRD scar 1st line treatment: GnRH agonist +…
- Trial name
- Young-PALETTA (NCT04819243)
- Testing
- Pabociclib, Endocrine(or ET + CDK4/6 inhibitors), Talazoparib, Atezolizumab, Pabociclib, Endocrine(or ET + CDK4/6 inhibitors), Talazoparib,
- Where
- South Korea
- Volunteers
- 178 people
- Sponsor
- Samsung Medical Center
Cesarean Section Complications, Scar; Deformity
Uterine Closure Techniques and Cesarean Scar Defect Risk
Cesarean operations are one of the most common obsetric operations and have an increasing trend in all over the world. However unfortunately the operation techniques have not been standardized yet.
- Trial name
- NCT05100147
- Testing
- Uterine closure during Cesarean section
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Mersin University
Incidence of cs Scar Infection
Normal Saline Versus Betadine Use to Reduce the Incidence of Wound Infection in Cesarean Section
This is a prospective randomized controlled study to the difference between using normal saline or betadine irrigation of wound prior to skin closure in reducing the incidence of wound infection after Cesarean section.
- Trial name
- NCT03725748
- Testing
- irrigation
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Wound Healing After MMS Surgery, BCC - Basal Cell Carcinoma
Effectiveness and Safety of X A-DERM™ Microsurfaced Acellular Dermal Matrix for Wound Healing After MOHS Surgery
The goal of this single-arm clinical trial is to learn about the effectiveness and safety of the X A-DERM™ mADM in promoting wound healing and improving scar formation after MMS surgery for removing BCC, SCC, or MIS lesions on…
- Conditions
- Wound Healing After MMS Surgery, BCC - Basal Cell Carcinoma, SCC - Squamous Cell Carcinoma, Melanoma In Situ
- Trial name
- NCT06919809
- Testing
- A microsurfaced ADM (acellular dermal matrix)
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- McGuire Institute
Keloid
Efficacy of Intralesional Triamcinolone and 8% Topical Pirfenidone for Treatment of Keloid Scars
The aim of the study is to assess the efficacy and safety of the combination of intralesional triamcinolone (at doses of 4mg / cm2 at intervals of 4 weeks) and topical pirfenidone 8% (every 8 hours continuously) compared with…
- Trial name
- LADISLAO (NCT02823236)
- Testing
- Topical Pirfenidone, Triamcinolone + Pirfenidone, Intralesional Triamcinolone
- Where
- Mexico
- Volunteers
- 102 people
- Sponsor
- Centro Dermatológico Dr. Ladislao de la Pascua
Scarring, Spinal Stenosis
dHACM in Lumbar Decompression and Microdiscectomy Surgery
Prospective evaluation of the safety and efficacy of dHACM on clinical outcomes in lumbar laminectomy and microdiscectomy patients as assessed by Oswestry Disability Index.
- Conditions
- Scarring, Spinal Stenosis, Herniated Disc
- Trial name
- NCT02300909
- Testing
- Lumbar Decompression Surgery, Microdiscectomy Surgery, Dehydrated Human Amnion/Chorion Membrane (dHACM)
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- MiMedx Group, Inc.
Keloid and Hypertrophic Scars
Polidocanol 1% and Steroid in Keloids and Hypertrophic Scars
we will inject intralesional polidocanol 1% in keloids and hypertrophic scars to decrease vascularity and decrease size of lesion compared to intralesional steroid as standard treatment line
- Trial name
- NCT07606391
- Testing
- Group 1 (polidocanol 1% group):, Group 2 (Triamcinolone acetonide group):, Group 3 (combined Triamcinolone acetonide and polidocanol 1% group):
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Sohag University
Acne Scars
Effect of Multiple Subcisions on Rolling Acne Scars
The purpose of this study is to find out whether the use of multiple subcisions over several visits will improve the appearance of rolling acne scars compared to no treatment.
- Trial name
- NCT02216864
- Testing
- Multiple Subcision
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Atrophic Scar
Carboxytherapy in the Treatment of Atrophic Scars
To evaluate the efficacy of CO2 versus fractional CO2 laser versus platelet rich plasma in treatment of atrophic scars using clinical assessment and ultrasonography
- Trial name
- NCT05695807
- Testing
- Carboxytherapy
- Volunteers
- 60 people
- Sponsor
- Cairo University
Acne Scars - Mixed Atrophic and Hypertrophic
Microneedling With Topical Preparations in the Treatment of Atrophic Post-acne Scars
To examine the anti-scarring effect of topical glycolic acid 35% combined with microneedling against that of topical insulin combined with microneedling for post acne scars
- Trial name
- NCT05600075
- Testing
- microneedling with topical glycolic acid 35%., microneedling with topical human insulin solution.
- Volunteers
- 30 people
- Sponsor
- Zagazig University
HIV, Hepatitis C
Impact of an Antibiotic (Rifaximin) on Liver Scarring in HIV-Infected Patients With Liver Disease
For HIV-infected patients who have access to treatment, liver diseases are a major cause of morbidity and mortality. Hepatitis C is the most frequently encountered liver condition in this population.
- Trial name
- NCT01654939
- Testing
- Rifaximin
- Sponsor
- Douglas T. Dieterich