Clinical trials: Scar
Wound Healing and Scar Quality Following Mohs Surgery and Excisional Dermatologic Surgery
Porcine Xenograft Versus Second Intention Healing
The purpose of this research study is to test whether it is better to allow patients with post- operative wounds on the legs to heal on their own without a covering or to use a porcine xenograft (skin graft that is made from pig…
- Trial name
- NCT03931746
- Testing
- Porcine xenograft
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- Northwell Health
Cicatrix, Hypertrophic
The Clinical Efficacy And Safety Of SkinStylus Microneedling System
The purpose of the trial is to provide objective evidence the SkinStylus may be used safely and effectively for the treatment of ventral torso hypertrophic scars.
- Trial name
- NCT03366194
- Testing
- SkinStylus Sterilock System
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Esthetic Education LLC
Cicatrix, Wound Healing
Investigation Into the Scar Reduction Potential of Prevascar (Interleukin-10)
The purpose of this study was to investigate the scar-reducing properties of eight doses of intradermal Prevascar (IL-10).
- Trial name
- NCT00984646
- Testing
- Prevascar
- Where
- United Kingdom
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Renovo
Atrophic Acne Scar
SkinPen Efficacy on Acne Scars on the Face and/or Back
This single-center, clinical trial will take place over a 90 day course followed by 1-month and 6-month post treatment visits to assess the efficacy and tolerability of the SkinPen device when used on both men and women on the…
- Trial name
- NCT02646917
- Testing
- Aesthetic Microneedling Treatment
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Bellus Medical, LLC
Cicatrix
Optimal Suture Choice for Improved Scar Outcomes
Certain parts of the body, such as the chest, back, and shoulders, are notorious for producing cosmetically poor scars after cutaneous surgery.
- Trial name
- NCT00938691
- Testing
- Intradermal Suture
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Dallas VA Medical Center
Hypertrophic Scars
Electromotive Drug Administration of Magnesium Sulphate on Hypertrophic Scar
In this study 80 patients will be randomly assigned into two equal groups (40 patients for each group): 1. Group A: Experimental: Magnesium Sulphate Iontophoresis for Postburn Hypertrophic Scar The study group includes 40…
- Trial name
- NCT06649188
- Testing
- Magnesium Sulphate Iontophoresis, traditional physical therapy program
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Atrophic Acne Scars
Subcision With Injection of Poly Deoxyribonucleotide Versus Subcision With Injection of Non-cross Linked Hyaluronic Acid in Rolling Acne Scars Treatment.
The aim of this study is to evaluate and compare the efficacy and safety of two different injectable agents combined with subcision for treating rolling acne scars.
- Trial name
- NCT07547956
- Testing
- subcision with PDRN vs HA injection
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Atrophic Acne Scar
2940nm Er:YAG Laser and 1927nm Thulium Laser in Improving Atrophic Acne Scars
Fractional non-ablative laser (FNAL) has been widely used in improving acne scarring. However, there was only one study reported efficacy and safety of the fractional non-ablative 1927nm thulium laser (FTL) and no studies have…
- Trial name
- NCT04813419
- Testing
- 1927nm thulium laser, 2940nm Er:YAG laser
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Transvaginal Ultrasound, Caesarean Section
Transvaginal Ultrasound Assessment of Caesarean Section Uterine Scar Closed by Single Versus Double Layer
This study aimed to evaluate uterine scar thickness and integrity using transvaginal ultrasonography in women randomly assigned to single versus double-layer closure of the uterine incision, with a comparison between the two…
- Conditions
- Transvaginal Ultrasound, Caesarean Section, Uterine Scar, Single Layer
- Trial name
- NCT07074522
- Testing
- Single-layer closure, Double-layer closure
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Skin Wound
Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Full-Thickness Skin Defects in Adults and Children
This phase II trial aims to evaluate the efficacy and safety of EHSG-KF (synonym denovoSkin) in comparison to meshed STSG in adults and children with full-thickness Skin defects.
- Trial name
- NCT03394612
- Testing
- EHSG-KF, STSG
- Where
- 7 sites in Italy, Netherlands and 1 more
- Volunteers
- 21 people
- Sponsor
- CUTISS AG
Scar
Forehead Scars Following Mohs Micrographic Surgery and Reconstruction for Skin Cancer
This study will test if the use of DysportTM (abobotulinumtoxinA) improves wound healing and scarring after Mohs surgery. Research in the laboratory as well as previous studies in humans have shown improved wound healing and…
- Trial name
- NCT01459666
- Testing
- Dysport (abobotulinumtoxinA), Bacteriostatic 0.9% Sodium Chloride (vehicle)
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- University Hospitals Cleveland Medical Center
Infertility, Complications; Cesarean Section
Does Cesarean Section Scar Defect (Niche) Affect Implantation Rate?
Cesarean scar defects (CSDs), i.e. deficient uterine scars following a cesarean section, involve discontinuity at the site of a previous Cesarean section scar.
- Trial name
- NCT02371486
- Testing
- hysteroscopic repair of cesarean section defect, Diagnostic Hysteroscopy, Ultrasound Scan
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Sheba Medical Center
Cicatricial Alopecia, Lichen Planopilaris
a Retrospective Study on the Systemic Treatment of LPP and FFA
This retrospective study aims to assess the effectiveness of systemic treatments for lichen planopilaris (LPP) and frontal fibrosing alopecia (FFA) in patients treated at the Erasmus MC University Medical Center.
- Conditions
- Cicatricial Alopecia, Lichen Planopilaris, Lichen Plano-Pilaris, Frontal Fibrosing Alopecia
- Trial name
- NCT06512766
- Testing
- Hydroxychloroquine, Methotrexate, Cyclosporine A
- Where
- Netherlands
- Volunteers
- 315 people
- Sponsor
- Erasmus Medical Center
Cicatrix, Scar Prevention
A Study of Single Ascending Dose of LEM-S401 in Healthy Participants
The primary objective of the study is to assess the safety and tolerability of single dose of LEM-S401 in healthy adult subjects.
- Trial name
- NCT04707131
- Testing
- LEM-S401
- Where
- South Korea
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Lemonex Inc.
Termination of Pregnancy
Termination of Pregnancy in Previous Scarred Uterus: PGE1 Versus Cervical Folleys
As mentioned above, previous studies have shown variable results and the best among these two is still in debate, so there must be re-evaluation of results on this topic.
- Trial name
- NCT07604051
- Testing
- PGE1 tablet, cervical folleys
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dr Mudassar Saeed Pansota
Uterine Scar From Previous Cesarean Delivery (Diagnosis)
Uterine Niche After Cesarean Section
In the past decade several articles have described a defect that can be seen on ultrasound at the site of cesarean delivery scar, known as a 'niche' .An incompletely healed scar is a long-term complication of cesarean delivery…
- Trial name
- AMSRM (NCT03787381)
- Testing
- Ultrasound
- Where
- Israel
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Atrophic Scar
Safety and Tolerability of Autologous Adipose-derived Mesenchymal Stem Cells Therapy in Adults With Atrophic Scars
The purpose of this clinical trial was to evaluate the safety and tolerability for 12 weeks after one dose of TRTP-101 in adults with atrophic scars.
- Trial name
- NCT06210919
- Testing
- TRTP-101
- Where
- South Korea
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- CellinCells
Acne Atrophica
The Efficacy and Safety of Dezocine Pretreatment for Pain Relief in Acne Scar Treatment of Fractional CO2 Laser
The Efficacy and Safety of Dezocine Pretreatment for Pain Relief in Acne Scar Treatment of Fractional CO2 Laser
- Trial name
- NCT05861063
- Testing
- Fractional CO2 laser, Dezocine
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Xijing Hospital
Cicatrix
Three Sutures With Different Absorption Rates for Lower Abdominal Incision
The previous studies have demonstrated that wedge excision combined modified buried vertical mattress suture (WE-MBVMS) provides better aesthetic outcomes than traditional ways.
- Trial name
- NCT05787171
- Testing
- WE-MBVMS using suture Vicryl (Polyglactin 910; Johnson & Johnson International, USA);, WE-MBVMS using suture PDS (polydioxanone; Johnson & Johnson International, USA), WE-MBVMS using suture Ethibond (polyester; Johnson & Johnson International, USA）
- Where
- China
- Volunteers
- 35 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Direct Brow Lift, Scarring
Onabotulinum Toxin A in Direct Brow Lift
The brow lift is a surgical procedure that has been practiced for several decades. A typical indication is brow ptosis, which can be secondary to involutional changes or facial nerve palsies.
- Trial name
- NCT04383912
- Testing
- Botox Injectable Product
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority