Clinical trials: Scabies
Scabies, Households
Comparing the Effectiveness of Individual vs. Household Treatment for Scabies in Lambaréné, Gabon
It is unclear whether individual treatment of scabies is similarly effective compared to household treatment. This study therefore compares these two treatment strategies with topical benzyl benzoate for treating scabies in…
- Trial name
- NCT04205669
- Testing
- Benzyl Benzoate 25% Topical Application Lotion
- Where
- Gabon
- Volunteers
- 104 people
- Sponsor
- Centre de Recherche Médicale de Lambaréné
Scabies
Dose-finding Study of Moxidectin for Treatment of Scabies
The effective dose of moxidectin to treat human scabies is not known. This study aims to provide proof of concept that a single dose of moxidectin is effective in eliminating the scabies parasite in humans and to enable the…
- Trial name
- NCT03905265
- Testing
- Moxidectin Oral Product
- Where
- 5 sites in Australia, Austria and 1 more
- Volunteers
- 22 people
- Sponsor
- Medicines Development for Global Health
Scabies
Multiple-Site Study to Evaluate the Therapeutic Equivalence of Permethrin Cream, 5% in the Treatment of Scabies
Study to Evaluate the Therapeutic Equivalence of Permethrin Cream 5%in the Treatment of Scabies.
- Trial name
- NCT03178942
- Testing
- Permethrin Cream, 5%, Elimite™ Cream (permethrin) 5%
- Where
- 15 sites in United States, El Salvador and 1 more
- Volunteers
- 254 people
- Sponsor
- Encube Ethicals Pvt. Ltd.
Lymphatic Filariasis, Scabies
Better Options for Lymphatic Filariasis Treatment
The goal of this clinical trial is to learn if mass drug administration with moxidectin in combination with diethylcarbamazine, and albendazole (MoxDA) can treat lymphatic filariasis, scabies and strongyloidiasis in children and…
- Conditions
- Lymphatic Filariasis, Scabies, Strongyloidiasis
- Trial name
- BOLT (NCT07159373)
- Testing
- MoxDA - Moxidectin + Diethylcarbamzine (DEC) + Albendazole, IDA - Ivermectin + DEC + albendazole
- Where
- Fiji
- Volunteers
- 5,100 people, healthy volunteers welcome
- Sponsor
- Medicines Development for Global Health
Scabies
Comparison of Permethrin-Based Treatment Strategies Against Scabies in Infants and Young Children
To compare the efficacy of different permethrin-based therapies for scabies infestations in infants and young children.
- Trial name
- NCT07247630
- Testing
- Permethrin 5%
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- College of Physicians and Surgeons Pakistan
Group A Streptococcal Infection, Scabies
Streptococcus Pyogenes Carriage Acquisition and Transmission Study
Group A Streptococcus (GAS) is a bacteria which causes severe infections and leads to deadly diseases such as rheumatic heart disease which kills over 300,000 people a year globally, particularly in low-income countries.
- Conditions
- Group A Streptococcal Infection, Scabies, Microbial Colonization
- Trial name
- SpyCATS (NCT05117528)
- Where
- The Gambia
- Volunteers
- 441 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Scabies
Ivermectin/ Permethrin for Scabies
Scabies is a skin disease characterized by intense itching that worsens at night. It is very contagious, still has a high occurrence rate, and impacts patient quality of life.
- Trial name
- NCT05819983
- Testing
- Ivermectin Tablets, Permethrin Cream
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Padjadjaran
Scabies
PK and Safety Study of Natroba Topical Suspension 0.9% in Subjects 1 Month to 3 Years 11 Months of Age With Scabies
A population of approximately 50 pediatric subjects will be enrolled to assess the PK of spinosad and benzyl alcohol for 3 hours following a single, full-body topical application (open label) on a single in-clinic visit (Day 1…
- Trial name
- NCT05310734
- Testing
- Spinosad Topical
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Cipher Pharmaceuticals Inc.
Lymphatic Filariases, Scabies
Fiji Integrated Therapy (FIT) - Triple Therapy for Lymphatic Filariasis, Scabies and Soil Transmitted Helminths in Fiji
Lymphatic Filariasis (LF), scabies and soil transmitted helminths (STH) are common neglected tropical diseases affecting the people of Fiji.
- Conditions
- Lymphatic Filariases, Scabies, Impetigo, Soil Transmitted Helminths
- Trial name
- FIT (NCT03177993)
- Testing
- 3 drug dose - IDA, 3 drug dose - IDA with second dose of ivermectin, 2 drug dose - DA
- Where
- Fiji
- Volunteers
- 4,773 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Scabies
Better Disease Control by Multidrug Regimen in Scabies
Scabies is associated with significant discomfort and social taboo. Existing treatment regimen frequently fails due to lack of patient compliance.
- Trial name
- NCT05198947
- Testing
- Permethrin Lotion 5%, Permethrin Lotion 5% and Oral Ivermectin 200 mcg/kg
- Volunteers
- 212 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Scabies
Sulfur 7% Cream Compared With Permethrin 5% Cream for Treating Scabies in Adults
This study compares two creams used to treat scabies, a common skin condition caused by mites that causes intense itching. Ninety adults with scabies were randomly assigned to receive either sulfur 7% cream or permethrin 5%…
- Trial name
- NCT07822672
- Testing
- Sulfur 7% cream, Permethrin 5% cream
- Where
- Vietnam
- Volunteers
- 90 people
- Sponsor
- Can Tho University of Medicine and Pharmacy
Scabies
A Dose Ranging Vehicle Controlled Study to Determine the Safety and Efficacy of Permethrin Foam, 5% and Permethrin Foam, 4% for the Treatment of Scabies
To determine and compare the safety and efficacy of permethrin foam 4% and permethrin foam 5% with that of vehicle in subjects with scabies.
- Trial name
- NCT02094716
- Testing
- Permethrin Foam 4%, Permethrin Foam 5%, Vehicle Foam
- Where
- 9 sites in United States, Dominican Republic and 2 more
- Volunteers
- 130 people
- Sponsor
- Mylan Inc.
Scabies
Place of Hygiene in Scabies's Treatment in Populations in Precarious Situations
Scabies is a parasitic pathology contracted mainly through human contamination. It is caused by a parasite (Sarcoptes Scabiei var.
- Trial name
- GALEHYGIE (NCT05271968)
- Testing
- Global management of scabies
- Where
- France
- Volunteers
- 218 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Scabies
Ivermectin Safety in Small Children
This trial will evaluate the safety, pharmacokinetics, and efficacy of ivermectin in scabies infected children weighing 5 to less than 15kg.
- Trial name
- ISSC (NCT04332068)
- Testing
- Oral ivermectin, Permethrin Cream
- Where
- 3 sites in Brazil, Kenya and 1 more
- Volunteers
- 240 people
- Sponsor
- University of Oxford
Atopic Dermatitis (AD), Scabies
Secondary Bacterial Infections and Nasal Colonization in Scabies and Atopic Dermatitis
This prospective observational study will evaluate the microbiological profile of secondary bacterial infection and nasal colonization in participants with scabies or atopic dermatitis.
- Conditions
- Atopic Dermatitis (AD), Scabies, Impetigo
- Trial name
- NCT07813611
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Scabies
Efficacy and Side Effects of Blacksoap® as Adjuvant Therapy of Scabies
Background: Scabies is a skin disease due to Sarcoptes scabiei. The transmission risk is high among communities living together, such as dormitories, boarding schools, nursing homes, and so on.
- Trial name
- NCT05025696
- Testing
- Blacksoap(R)
- Where
- Indonesia
- Volunteers
- 78 people
- Sponsor
- Universitas Indonesia
Scabies
PCR (Polymerase Chain Reaction) Assay for Diagnosis of Sarcoptes Scabiei
The main objective of this study is to identify unique DNA sequences within the genome of human scabies that can be utilized to identify the parasite through PCR.
- Trial name
- NCT02254564
- Where
- 5 sites in United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Seton Healthcare Family
Scabies
Therapy for Scabies With Two Differently Concentrated Permethrin Creams
The multi-center, prospective, randomized, double-blind phase III clinical trial will primarily investigate the efficacy and safety of treatment of scabies with Permethrin Cream 5% (approved drug InfectoScab 5% Cream) in direct…
- Trial name
- SKABUP (NCT06380452)
- Testing
- 5% Permethrin Creme, 10% Permethrin Creme
- Volunteers
- 220 people
- Sponsor
- Infectopharm Arzneimittel GmbH
Scabies
Phase 3 Trial to Assess the Safety and Efficacy of Natroba for the Treatment of Scabies
To assess the safety and efficacy of Natroba (spinosad) topical suspension versus placebo for the complete cure of scabies after a single treatment.
- Trial name
- NCT02485704
- Testing
- spinosad topical suspension, 0.9%
- Where
- 7 sites in United States
- Volunteers
- 280 people
- Sponsor
- ParaPRO LLC
Scabies
Oral Ivermectin Versus Topical Permethrin to Treat Scabies in Children and Adults
Scabies remains a frequent condition that affects adults and children. The aim of this study is to compare the efficacy and safety of two drug treatments against scabies in children and their close contacts.
- Trial name
- SCRATCH (NCT02407782)
- Testing
- Ivermectin, Permethrin
- Where
- 29 sites in France, Guadeloupe
- Volunteers
- 1,092 people
- Sponsor
- University Hospital, Bordeaux