Clinical trials: Sarcopenia
Sarcopenia, Body Weight Changes
Effects of Resistance Training on Physical Performance, Health and Quality of Life in Elderly (RTCHealth)
Physical exercise is considered an important intervention for promoting well-being and healthy aging. The purpose of the present study was to determine the effects of moderate-to-high intensity resistance training circuit on…
- Conditions
- Sarcopenia, Body Weight Changes, Quality of Life
- Trial name
- RTCHealth (NCT03551132)
- Testing
- Exercise test
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Colorectal Cancer (CRC), Sarcopenia
TIVA Versus Balanced Anesthesia on Muscle Mass in CRC Surgery
This study is aimed at clarifying changes in body composition during the perioperative period and identifying risk factors for skeletal muscle mass loss in patients with colorectal cancer.
- Trial name
- TIVABAL-CRC (NCT07237438)
- Testing
- total intravenous anaesthesia, sevoflurane anaesthesia
- Where
- Romania
- Volunteers
- 40 people
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Pre-sarcopenia, Old Age; Debility
Effectiveness of Power Training in Older Women With Pre-sarcopenia
This is a randomized, parallel, double-blind clinical trial. The main objective is to compare the efficacy of resistance training based on power training, multimodal exercise with non-specific exercises and a control group on…
- Trial name
- POSARC (NCT05870046)
- Testing
- Power training in women older than 65 years with pre-sarcopenia, Multimodal and nonspecific exercises in women older than 65 years with pre-sarcopenia
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Protein Malabsorption, Nutrition Disorders
Bioavailability of Proteins From Plant Based Diets
The quality of protein intake has an important role within the nutritional needs of people throughout their lives around the world, particularly in developing countries and in particular during pregnancy and early childhood.
- Conditions
- Protein Malabsorption, Nutrition Disorders, Sarcopenia
- Trial name
- NCT03492190
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Eduardo Ferriolli
Sarcopenia, Chronic Kidney Diseases
Sarcopenia, Fall and Osteoporosis in Chronic Kidney Disease
This study is a cross-sectional study that wishes to investigate whether there is an increased incidence of sarcopenia in patients with chronic kidney disease compared to the Danish background population.
- Conditions
- Sarcopenia, Chronic Kidney Diseases, Osteoporosis
- Trial name
- NCT04515342
- Testing
- DXA, Muscle strength and function assessment, Blood samples
- Where
- 2 sites in Denmark
- Volunteers
- 140 people
- Sponsor
- Herlev Hospital
Muscle Weakness, Dynapenia
Mirror Neurons in Older Participants
A critical problem facing aging adults is muscle weakness. Whereas scientists have traditionally attributed the loss of muscle strength with aging to muscle atrophy, emerging evidence suggests that impairments in the…
- Conditions
- Muscle Weakness, Dynapenia, Sarcopenia
- Trial name
- MNOP (NCT03946709)
- Testing
- Action Observation
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Sarcopenia in Elderly, Muscle Atrophy
Effects of Cyclical Blood Flow Restriction Exercise on Muscle Hypertrophy and Capillaries in Older Adults
The purpose of this study was to learn if low-load resistance exercise combined with cyclical blood flow restriction (BFR) could improve small blood vessel structure and muscle size in older adults.
- Conditions
- Sarcopenia in Elderly, Muscle Atrophy, Aging
- Trial name
- NCT07689487
- Testing
- Blood Flow Restriction (BFR), Conventional Low-Load Resistance Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Sarcopenia
Ursolic Acid-Standardized Apple Phospholipid-formulated Supplementation for Muscle Strength and Physical Performance in Older Adults With Mild Sarcopenia: A Randomized, Double-Blind, Placebo-Controlled Trial
Sarcopenia is an age-related condition characterized by loss of muscle strength and physical performance, leading to increased risk of falls and disability.
- Trial name
- NCT07562698
- Testing
- Ursolic Acid-Standardized Apple Pomace Extract
- Where
- Pakistan
- Volunteers
- 105 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Sarcopenia, Obesity
Relationship Between Glycemic Control and Irisin in Type 2 Diabetic Patients With Sarcopenic or Non-sarcopenic Obesity
The goal of this observational study is to compare glycemic control and irisin levels in subjects with diabetes mellitus type 2 with sarcopenic obesity vs non-sarcopenic obesity.
- Conditions
- Sarcopenia, Obesity, Diabetes Mellitus, Type 2
- Trial name
- NCT05908812
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Sarcopenia, Frailty
BandPass: A Remote Monitoring System for Sarcopenia and Functional Decline Phase II Aim 4
This study evaluates a home-based strengthening program supported by the BandPass system, which includes a Bluetooth-enabled resistance exercise band, a mobile app that provides real-time feedback, and a clinician dashboard for…
- Trial name
- NCT07421648
- Testing
- BandPass System
- Where
- 2 sites in United States
- Volunteers
- 39 people
- Sponsor
- SynchroHealth LLC
End Stage Kidney Disease
Sarcopenia and Physical Performance in Hemodialysis Patients
Many systems such as the cardiovascular, pulmonary, musculoskeletal, hematological, immunological, gastrointestinal, central nervous system are affected due to decreased kidney function.
- Trial name
- NCT04669184
- Volunteers
- 26 people
- Sponsor
- Hacettepe University
Sarcopenia, Lung Cancer
Lung Cancer Surgery in Sarcopenia Patients With Old Age
The presence of sarcopenia before lung resection surgery might be an important factor of short-term and long-term prognosis in lung cancer patients.
- Trial name
- LUCAS-PEN (NCT05346185)
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Seoul National University Hospital
Sarcopenia
Feasibility of a Resistance Exercise and Dietary Protein Intervention in Elderly People in Practice (ProMuscle 65PK)
The purpose of this pilot study is to investigate the feasibility and potential impact of a combined resistance exercise and increased protein intake intervention in (frail) elderly, in a real-life setting.
- Trial name
- NCT02434289
- Testing
- Dietary protein products, Resistance exercise training
- Where
- Netherlands
- Volunteers
- 23 people
- Sponsor
- Wageningen University
Knee Osteoarthritis
Evaluation of Mobility in Subjects With Severe Knee Osteoarthritis Who Are to Undergo Total Knee Replacement
Osteoarthritis (OA) is the most common joint disease. It is characterized by a progressive destruction of all the components of the joint, especially the cartilage.
- Trial name
- MOUV-GOPRO (NCT05488093)
- Testing
- X-sens sensor
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Muscle Function, Handgrip Strength Test
Muscle Assessment in Women Who Have Undergone Roux-en-Y Gastric Bypass Surgery
The purpose of this study is to assess muscle function in women at least two years after being submitted to Roux-en-Y Gastric Bypass Surgery and compare with a control group
- Trial name
- FUBA (NCT02811393)
- Testing
- Assess muscle function
- Where
- Chile
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Chile
Endovascular Aneurysm Repair (EVAR)
Evaluating the Impact of Psoas Muscle Size, Composition, and Clinical Frailty on Long-term Outcomes Following Elective Endovascular Aneurysm Repair
Sarcopenia, which is characterized by the progressive loss of skeletal muscle mass and strength, has emerged as a significant prognostic biomarker in the field of vascular surgery, particularly regarding endovascular aneurysm…
- Trial name
- NCT06864247
- Testing
- No Intervention: Observational Cohort
- Where
- Taiwan
- Volunteers
- 525 people
- Sponsor
- National Taiwan University Hospital
Diabetes, Sarcopenia
Effects of Insulin on Hypotension and Sarcopenia
In this study investigator's aim to determine the impact of insulin therapy on hypotension and sarcopenia
- Conditions
- Diabetes, Sarcopenia, Hypotension, Orthostatic
- Trial name
- NCT03248271
- Testing
- Insulin Lispro
- Where
- Canada
- Sponsor
- Kenneth Madden
Critical Illness, Post Intensive Care Syndrome (PICS)
Effectiveness of a Structured Multidimensional Tele-rehabilitation Intervention in Cardiac Patients With Post-Intensive Care Syndrome (CARDIO-PICS)
This two-arm, parallel-group randomized clinical trial investigates the effectiveness of an additional telerehabilitation program compared with standard care in patients with Post-Intensive Care Syndrome (PICS).
- Conditions
- Critical Illness, Post Intensive Care Syndrome (PICS), Cardiopathy
- Trial name
- CARDIO-PICS (NCT07599306)
- Testing
- Tele-rehabilitation, Standard of Care
- Where
- Italy
- Volunteers
- 326 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Sarcopenia
Sarcopenia and Intervention Physical Therapy
To evaluate and compare the effectiveness of neuromuscular electrical stimulation (NMES) and low-load resistance training with blood flow restriction (BFR) in improving muscle mass, strength, functional performance, and quality…
- Trial name
- NCT07013604
- Testing
- Neuromuscular Electrical Stimulation (NMES) Group,Resistance + BFR Group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pharos University in Alexandria
Liver Cirrhosis, Non-Alcoholic Fatty Liver Disease
Ultrasound Assessment of Sarcopenia in Patients With Chronic Liver Disease: the SARCOLIVER Study
Sarcopenia is a complex multifactorial syndrome which could be present in older age (primary sarcopenia) or earlier in chronic disease (secondary sarcopenia).
- Conditions
- Liver Cirrhosis, Non-Alcoholic Fatty Liver Disease, Hepatocellular Carcinoma
- Trial name
- SARCOLIVER (NCT06101758)
- Testing
- Handgrip strength test, total body Dual Energy X-Ray Absorptiometry (DXA), Muscle ultrasound
- Where
- Italy
- Volunteers
- 125 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS