Clinical trials: Sarcopenia
Metabolic Syndrome, Aging
Sustainable Exercise and Nutrition Programs for Managing Metabolic Disorders in Older Women
This study aims to evaluate the impact of sustainable diet and exercise programs on metabolic health and quality of life in older women.
- Conditions
- Metabolic Syndrome, Aging, Sarcopenia, Obesity
- Trial name
- NCT07015307
- Testing
- Sustainable Diet Program, Supervised Physical Exercise Program, Combined Sustainable Diet and Exercise Program
- Where
- Spain
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Alicante
Metastatic Non-small Cell Lung Cancer, Neoplasm
Body Composition and Inflammatory-Metabolic Indices in Immunotherapy-Treated Metastatic Non-Small Cell Lung Cancer: The SARC-CTI Study
This retrospective, single-center observational cohort study evaluates inflammatory-metabolic, cachexia-related, and computed tomography (CT)-derived body-composition markers in patients with metastatic non-small cell lung cancer…
- Trial name
- SARC-CTI (NCT07192926)
- Testing
- Immune Checkpoint Inhibitor-Based Therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 155 people
- Sponsor
- Ankara Etlik City Hospital
Sarcopenia in Elderly
Blood Flow Restriction Training in Acute Geriatric Rehabilitation
Background: Older adults have a reduced ability to build and maintain muscle mass due to age-related changes in the muscular system.
- Trial name
- NCT07291765
- Testing
- Stationary Bike + Blood-Flow-Restriction, Acute geriatric rehabilitation + No additional Intervention
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- University Hospital, Bonn
Sarcopenia, Long Term Care Facility
Effectiveness of RPT With Elastic Band in Tx of Sarcopenia in LTCFs
The goal of this clinical trial is to evaluate the effectiveness of progressive resistance training using elastic bands in treating and delaying the progression of sarcopenia among older adults in long-term care facilities.
- Trial name
- NCT07513025
- Testing
- elastic band
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Cishan Hospital, Ministry of Health and Welfare
Sarcopenia, Aging
Reducing Falls With Progressive Resistance Training for the Oldest Old Adults With Reduced Muscle Strength
This study will investigate the effects of 12 months of high-intensity progressive resistance training compared with a control group on fall-rate in older adults with reduced muscle strength.
- Trial name
- ReFit (NCT05691166)
- Testing
- High-intensity progressive resistance training, Written physical activity guidance
- Where
- Norway
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Sarcopenia
Evaluation of Safety and Efficacy of a Digital Therapeutic Device to Improve Strength in Sarcopenia (Sarc-DTx)
This clinical trial aims to demonstrate that the use of a digital therapeutic device (exoDTx) in patients with sarcopenia is superior to self-exercise in terms of muscle strength improvement and safety.
- Trial name
- NCT07319377
- Testing
- exoDTx, Self-exercise (Educational Material)
- Where
- 2 sites in South Korea
- Volunteers
- 130 people
- Sponsor
- Exosystems
Sarcopenia in Elderly, Hospital Associated Disability
Preventing Hospital Associated Disability in Older Patients: Individualized Nutrition and Exercise Strategy
Aproximately a third of persons older than 70 years lose physical function and ability to take care of themselves during a stay at a hospital. This is associated to an increased risk of readmission and mortality.
- Conditions
- Sarcopenia in Elderly, Hospital Associated Disability, Malnutrition Elderly, Physical Function
- Trial name
- PrevHAD RCT (NCT07373587)
- Testing
- Exercise
- Where
- Denmark
- Volunteers
- 360 people
- Sponsor
- Bispebjerg Hospital
Sarcopenia
Sternocleidomastoid Thickness in Sarcopenia
In order to prevent sarcopenia in intensive care patients and to guide nutritional therapy, evaluation of muscle thickness with ultrasonography is a modern, simple and non-invasive procedure routinely performed by Anesthesiology…
- Trial name
- NCT05928845
- Testing
- Muscle thickness measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Namik Kemal University
Breast Cancer, Frailty
Multicomponent Prehabilitation in Older Adults With Breast Cancer
Older adults with breast cancer frequently present with frailty, decreased functional reserve, and increased risk of postoperative complications.
- Conditions
- Breast Cancer, Frailty, Sarcopenia, Aging
- Trial name
- PREHAB-BC65 (NCT07531836)
- Testing
- Home-based Multicomponent Prehabilitation (Vivifrail), Supervised Multicomponent Prehabilitation, Comprehensive Geriatric Assessment and Optimization
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Fundacion Miguel Servet
Sarcopenia
Sarcopenia Magnetic Resonance Imaging Evaluation (SUSIE)
The goal of the proposed research is to investigate Magnetic Resonance (MR) Fingerprinting and P-MRS (Phosphorus-31 MR Spectroscopy) imaging for characterization of skeletal muscle in heart failure patients with sarcopenia.
- Trial name
- SUSIE (NCT04869813)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- The Cleveland Clinic
Ventilator Weaning, Sarcopenia
Comparison of Sarcopenia Index, Diaphragm Ultrasonography, and Traditional Weaning Parameters in Predicting Successful Weaning From Mechanical Ventilation
This study investigates whether the Sarcopenia Index (SI = serum creatinine/cystatin C × 100), a simple biomarker derived from routine blood tests, can predict weaning success in critically ill patients undergoing invasive…
- Conditions
- Ventilator Weaning, Sarcopenia, Diaphragm Ultrasonography
- Trial name
- NCT07844421
- Testing
- sarcopenia index, diaphragma ultrasound, parameters of mechanical ventilation (MV)
- Volunteers
- 80 people
- Sponsor
- Kocaeli City Hospital
Sarcopenia, Cirrhosis, Liver
LIver FRAilty Management IN Cirrhosis (LIFRAMIN)
The goal of this clinical trial is to compare food for special medical purposes (Aminolife Plus, by Piemme Pharmatech) vs. placebo in improving muscle mass and function in a cohort of cirrhotic patients.
- Conditions
- Sarcopenia, Cirrhosis, Liver, Malnutrition; Protein
- Trial name
- LIFRAMIN (NCT06573229)
- Testing
- Aminolife Plus by Piemme Pharmatech, Italy
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Sarcopenia, Sarcopenia in Elderly
Effects of Aquatic Exercise in Older Adults With Sarcopenia:A Randomized Trial
Sarcopenia is a geriatric syndrome characterized by age-related loss of skeletal muscle mass, strength, and physical performance, leading to increased risk of falls, functional decline, and reduced quality of life.
- Trial name
- NCT07575958
- Testing
- Aquatic Exercise Program, Home Exercise Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Sarcopenic Obesity, Acupuncture Treatment
The Effect of Acupuncture on Sarcopenia and Obesity in Patients With Sarcopenic Obesity.
Sarcopenia is defined by the European Working Group on Sarcopenia in Older People (EWGSOP) as "a syndrome characterized by progressive and generalized loss of skeletal muscle mass and strength, carrying a risk of adverse outcomes…
- Conditions
- Sarcopenic Obesity, Acupuncture Treatment, Exercise
- Trial name
- Sarcopenia (NCT07797140)
- Testing
- Diet and exercise, Acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Ayşe Ukbe Baykut
Multiple Sclerosis, Sarcopenia
Investigation of the Prevalence of Sarcopenia and Dynapenia According to Disease Stage in Patients With Multiple Sclerosis and Evaluation of the Relationship Between Sarcopenia Severity and Clinical and Functional Parameters
This cross-sectional observational study aims to determine the prevalence of sarcopenia and dynapenia across disability stages in patients with multiple sclerosis (MS) and investigate their associations with clinical and…
- Conditions
- Multiple Sclerosis, Sarcopenia, Dynapenia
- Trial name
- MS-Sarcopenia (NCT07842731)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Atılım University
Sarcopenia
Effects of Omega-3 and Whey Protein Supplementation on Lean Mass in Older Adults
To evaluate the effect of omega-3 supplementation combined with whey protein intake on lean mass, muscle strength, metabolomic and lipidomic profiles, and biomarkers of oxidative stress and inflammation in older adults undergoing…
- Trial name
- W-3 and Whey (NCT05862779)
- Testing
- Omega 3 + Whey Protein
- Where
- Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Intracerebral Hemorrhage, Subarachnoid Hemorrhage
Al Prediction of Sarcopenia Risk in Neurocritical ICU Patients
This prospective observational study aims to evaluate sarcopenia in intensive care patients with intracranial pathologies using ultrasound and to compare the predictive performance of different artificial intelligence models.
- Conditions
- Intracerebral Hemorrhage, Subarachnoid Hemorrhage, Subdural Hematoma, Epidural Hematoma
- Trial name
- NCT07712198
- Testing
- Prospective Observational Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Trabzon Kanuni Education and Research Hospital
Chronic Kidney Disease, Osteoporosis
Clinical Study on a New Diagnostic Strategy for Osteoporosis and Sarcopenia in Chronic Kidney Disease Patients Based on MRI-FF
This is a single-center, observational cohort study aiming to validate the diagnostic value of MRI-FF in identifying osteoporosis and sarcopenia in patients with chronic kidney disease (CKD).
- Trial name
- NCT07645794
- Testing
- MRI-FF Scan
- Where
- China
- Volunteers
- 868 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Sarcopenia in Elderly
Tai Chi Exercise to Improve Quality of Life and Depression in Elderly With Sarcopenia
This study aims to evaluate the effects of Tai Chi exercise on quality of life and depressive symptoms in elderly with sarcopenia.
- Trial name
- NCT07831356
- Testing
- Tai Chi Exercise, Elderly exercise (senam lansia)
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Hasanuddin University
Metabolic Syndrome, Obesity
A Clinical Study on Using Multimodal Ultrasound to Assess Muscle Mass in Metabolic Diseases
This study aims to evaluate the clinical value of multimodal ultrasound for assessing muscle mass in patients with metabolic diseases, including metabolic syndrome, type 2 diabetes, and simple obesity.
- Conditions
- Metabolic Syndrome, Obesity, Sarcopenia, Type 2 Diabetes
- Trial name
- NCT07836088
- Where
- China
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Zhangzhou Municipal Hospital