Clinical trials: Sacral Disorder
Knee Osteoarthritis
ACB With S-ESPB Versus ACB With iPACK for Knee Arthroplasty
This study will compare two regional anesthesia strategies for pain management after total knee arthroplasty in adults. Both strategies use an adductor canal block (ACB) to provide analgesia while preserving quadriceps muscle…
- Trial name
- NCT07288970
- Testing
- Adductor Canal Block, Sacral Erector Spinae Plane Block, iPACK Block
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Poznan University of Medical Sciences
Ulcerative Colitis, Inflammatory Bowel Diseases
BOOM-IBD2 Pivotal Clinical Trial
Ulcerative colitis is a long-lasting condition that causes swelling and sores in the large intestine. This study tests whether a small device placed under the skin can help reduce bowel urgency in people with ulcerative colitis.
- Trial name
- NCT06571669
- Testing
- Neuromodulation
- Where
- 19 sites in United States
- Volunteers
- 137 people
- Sponsor
- Boomerang Medical
Physical Therapy Modalities
Effects of Physical Therapy Associated With Photobiomodulation on Myelomeningocele
Myelomeningocele is a severe type of spina bifida, resulting from improper closure of the neural tube. This condition drastically affects the structures of the spinal cord, as a result the spinal cord, nerve roots and meninges…
- Trial name
- NCT04425330
- Testing
- physiotherapy exercises, PBM
- Volunteers
- 30 people
- Sponsor
- University of Nove de Julho
Urinary Incontinence
Comparison of Burch Urethropexy and Mid-urethral Sling Performed Concomitantly With a Sacral Colpopexy
I. Specific Aims Pelvic organ prolapse is a common and distressing condition that is frequently associated with stress urinary incontinence (SUI) and often requires surgical repair.
- Trial name
- NCT00934999
- Testing
- Burch urethropexy, Synthetic mid-urethral sling (TVT)
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Mayo Clinic
Refractory Overactive Bladder
Clinical Trial of Sacral Neuromodulation for Treatment of Refractory Overactive Bladder (OAB)
Evaluate the long-term clinical effectiveness and safety of the PINS Sacral Neuromodulation to patients with refractory Overactive Bladder.
- Trial name
- NCT02619721
- Testing
- PINS SNS
- Where
- China
- Volunteers
- 7 people
- Sponsor
- Beijing Pins Medical Co., Ltd
Low Anterior Resection Syndrome (LARS)
Early Implementation of Sacral Neuromodulation in Patients With Low Anterior Resection Syndrome.
A randomized, prospective, multicenter, open-label, pragmatic pilot study of patients with Low Anterior Resection Syndrome treated early (<120 days after discharge following intestinal bypass reconstruction) with sacral nerve…
- Trial name
- NCT07761884
- Testing
- Sacral neuromodulation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Overactive Bladder, Non Obstructive Urinary Retention
Sacral Neuromodulation and Pudendal Somatic Afferents
Sacral neuromodulation is a well-excepted minimally invasive procedure for the treatment of overactive bladder and non-obstructive urinary retention.A tined lead with 4 stimulation electrodes is placed through the third or fourth…
- Trial name
- NCT03614754
- Testing
- Somatosensory evoked potentials
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universiteit Antwerpen
Multiple Sclerosis, Lower Urinary Tract Symptoms
Effect of Motor Cortex Versus Sacral Magnetic Stimulation in Multiple Sclerosis Patients With Urinary Tract Dysfunction
This work is intended to assess the effect of repetitive magnetic stimulation on the sacral roots versus repetitive magnetic stimulation on motor cortex in multiple sclerosis patients with the lower urinary tract dysfunction.
- Trial name
- NCT03434873
- Testing
- magnetic stimulation
- Volunteers
- 40 people
- Sponsor
- Cairo University
Tarlov Cysts
A Randomized Controlled Study on the Treatment of Sacral Canal Cysts With Sacral Canal Reinforcement
The subject will treat 68 patients with symptomatic sacral canal cysts as the research object, and adopt a randomized controlled research method, respectively, using two methods of reinforcement and reconstruction of the nerve…
- Trial name
- ARCSTSCC (NCT04465305)
- Testing
- entraped treatment, plasty treatment
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Peking University Third Hospital
Urgency Urinary Incontinence
Sacral Neuromodulation and the Microbiome
Sacral neuromodulation (SNM) which is approved as a treatment for men and women with urgency urinary incontinence (UUI), urgency frequency syndrome, urinary retention and anal incontinence, is a procedure designed to deliver…
- Trial name
- NCT02833402
- Testing
- InterStim Therapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Northwestern University
Central Nervous System Diseases
The Effect of Craniosacral Therapy as Additive Procedure.
This observational, retrospective study has shown, that the addition of craniosacral therapy to the Vojta method has improved the effects of the therapy in 6 months follow-up period.
- Trial name
- COREHNERV (NCT05722756)
- Testing
- craniosacral therapy
- Volunteers
- 51 people
- Sponsor
- Wroclaw Medical University
Spinal Cord Injury, Acute, Neurogenic Bladder
Sacral Nerve Stimulation in Improving Bladder Function After Acute Traumatic Spinal Cord Injury
The purpose of this study is to see what effects sacral neuromodulation has on bladder function and quality of life in patients with acute spinal cord injury.
- Conditions
- Spinal Cord Injury, Acute, Neurogenic Bladder, Incontinence, Urinary Tract Infections
- Trial name
- NCT03083366
- Testing
- PrimeAdvanced Surescan 97702 Neurostimulator - Medtronic (Minneapolis, MN)
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- University of Utah
Urinary Urge Incontinence
InterStim® Sacral Nerve Modulation Cycling Study
The study will assess the effects of different InterStim cycling settings on urinary urge incontinence.
- Trial name
- NCT01957137
- Testing
- InterStim® (Device Programming)
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- MedtronicNeuro
Irritable Bowel Syndrome
Multimodal Stimulation Before and After Sacral Nerve Stimulation for Irritable Bowel Syndrome
Sacral nerve stimulation (SNS) has become a well-established treatment for patients with fecal incontinence since 1995. The mechanism of action of SNS is still not fully understood but recent studies have shown changes in both…
- Trial name
- NCT01950715
- Testing
- sacral nerve stimulation
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- University of Aarhus
Fecal Incontinence
Efficacy of Sacral Nerve Stimulation Before Definitive Implantation
Sacral nerve stimulation (SNS) is an emerging treatment for patients with severe fecal incontinence. The test stimulation is minimally invasive, associated to low morbidity and relatively cheap.
- Trial name
- SNStest (NCT00522691)
- Testing
- sacral nerve stimulation
- Where
- Switzerland
- Sponsor
- University of Lausanne Hospitals
Periodontal Diseases
Antibacterial and Anti-biofilm Activity of Frankincense Extract Against Porphyromonas Gingivalis
Boswellia sacra Flueck. oleoresin extract (frankincense) was traditionally used in the treatment of different diseases as respiratory, rheumatoid arthritis, and bacterial infections.
- Trial name
- NCT04705714
- Testing
- Frankincense Extract
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Low Anterior Resection Syndrome
Pathway of Low Anterior Resection Syndrome Relief After Surgery: a Feasibility Study
Currently, no standard exists for the treatment and management of Low Anterior Resection Syndrome (LARS)- a common disorder that affects patients who have had part of their bowel removed due to colorectal cancer.
- Trial name
- POLARiS (NCT05319054)
- Testing
- Sacral NeuroModulation, Trans-Anal Irrigation, Optimised Conservative Management
- Where
- 4 sites in United Kingdom
- Volunteers
- 187 people
- Sponsor
- Cardiff and Vale University Health Board
Pressure Injury Stage 2
Open-label Study to Evaluate the Efficacy and Safety of Fespixon Cream for the Treatment of Pressure Injury in Sacrum and Greater Trochanter Wound
Open-label Study to Evaluate the Efficacy and Safety of Fespixon Cream for the Treatment of Pressure Injury in Sacrum and Greater Trochanter Wound
- Trial name
- NCT05317442
- Testing
- Fespixon Cream
- Where
- 3 sites in Taiwan
- Volunteers
- 10 people
- Sponsor
- Taipei Medical University WanFang Hospital
Fecal Incontinence
Dose Response Curve - Sacral Nerve Stimulation for Faecal Incontinence
The purpose of this study is to determine if subsensory stimulation (amplitude) will maintain same continence in patients treated with Sacral Nerve Stimulation (SNS) for faecal incontinence as stimulation with amplitude at…
- Trial name
- NCT01130870
- Testing
- Sensory Threshold, 75% of sensory threshold - Amplitude, 50% of sensory threshold - Amplitude
- Where
- Denmark
- Volunteers
- 19 people
- Sponsor
- University of Aarhus