Clinical trials: SARS-CoV2 Infection
Corona Virus Infection
COVID-19 Antigen Rapid Test Evaluation in Low-Prevalence Setting
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the resulting COVID-19 pandemic present important diagnostic challenges.
- Trial name
- CV006 (NCT05911074)
- Testing
- The Abbott Panbio™ COVID-19 Ag Rapid Test
- Where
- Botswana
- Volunteers
- 7,274 people, healthy volunteers welcome
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Healthy, Chronic Stable Illness
COVID-19 Study to Assess Immunogenicity, Safety, and Tolerability of Moderna mRNA-1273 Vaccine Administered With Casirivimab+Imdevimab in Healthy Adult Volunteers
The primary objectives of the study are: To evaluate the extent of effect, if any, of REGN10933+REGN10987 administration on vaccine-induced neutralizing antibody responses to SARS-CoV-2 by Moderna mRNA-1273 To evaluate the time…
- Trial name
- NCT04852978
- Testing
- casirivimab+imdevimab, Moderna mRNA-1273 vaccine
- Where
- 6 sites in United States
- Volunteers
- 295 people, healthy volunteers welcome
- Sponsor
- Regeneron Pharmaceuticals
COVID-19
Profile of COVID-19 Patients Related to Fatigue
More than half of recovered COVID-19 patients experience fatigue. Studies are needed to define the profile of these patients. The objective of this study is to evaluate the profile of surviving patients of COVID-19 in relation to…
- Trial name
- NCT05731817
- Testing
- Observational study
- Where
- Spain
- Volunteers
- 398 people
- Sponsor
- Universidad de Granada
COVID19
Characteristics of Critically Ill COVID 19 Patients
COVID19 is n outbreak with unpredictable outcome
- Trial name
- NCT04465058
- Testing
- COVID19
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
COVID-19
Seroprevalence of Infection-induced SARS-CoV-2 Antibodies (COVID-19) in Children
It is unknown what proportion of children have been exposed to SARS-CoV-2 and how many have antibodies among children seeking medical care for non-Covid-19 related conditions.
- Trial name
- NCT05358626
- Testing
- SARS-CoV-2 IgG Antibody testing
- Where
- Vietnam
- Volunteers
- 4,032 people
- Sponsor
- National Children's Hospital, Vietnam
Is the Coronovac Vaccine Effective in Patients Receiving Chemotherapy
Investigation of the Effectiveness of CoronaVac Vaccine in Cancer Patients With Active Chemotherapy and Comparison With Healthy People.
This study aimed to investigate the effectiveness of CoronaVac vaccine, which is more than 90% protective in healthy people, in cancer patients receiving active chemotherapy.
- Trial name
- NCT04765215
- Testing
- CoronoVAC
- Where
- Turkey (Türkiye)
- Volunteers
- 291 people, healthy volunteers welcome
- Sponsor
- Asoc. Prof. Erdoğan Selçuk Şeber
Senile Cataract
VRQOL in Cataract Patients During the COVID-19 Pandemic
The aim of this questionnaire survey is to evaluate the improvement in vision-related quality of life before and after cataract surgery using the National Eye Institute Visual Function Questionnaire 25 and the delay of…
- Trial name
- NCT04468308
- Testing
- Questionnaire
- Where
- Austria
- Volunteers
- 116 people
- Sponsor
- Medical University Innsbruck
HER2-positive Breast Cancer
An Expanded Access Study to Provide at Home Subcutaneous Administration of Pertuzumab and Trastuzumab Fixed-Dose Combination (PH FDC SC) for Patients With HER2-Positive Breast Cancer During the COVID-19 Pandemic
This single arm, multicenter study provides the pertuzumab and trastuzumab fixed-dose combination formulation for subcutaneous injection (PH FDC SC) administered at home by a home health nursing provider for patients with human…
- Trial name
- NCT04395508
- Testing
- Pertuzumab and Trastuzumab Fixed-Dose Combination for Subcutaneous Administration (PH FDC SC)
- Where
- 12 sites in United States
- Sponsor
- Genentech, Inc.
Infection Viral
Clinical Characteristics of Coronavirus Disease 2019 (COVID-19) in Pregnancy
The Novel Coronavirus (2019-nCoV), also known as Wuhan coronavirus, causes the 2019-nCoV acute respiratory disease.
- Trial name
- COVID-preg (NCT04319016)
- Testing
- pregnant women with laboratory-confirmed 2019-n-CoV
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Federico II University
Inflammatory Bowel Diseases
Survey Study About Endoscopy During COVID-19 Pandemic for IBD Doctors
Performance of diagnostic or therapeutic endoscopic procedures in inflammatory bowel disease (IBD) patients can be challenging during a viral pandemic; the main concerns being the safety and protection of patients and health care…
- Trial name
- NCT04970849
- Testing
- observation
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
COVID-19 Pandemic, Diabetes
Study on the Effect of Incentive Spirometer-based Respiratory Training on the Long COVID-19
The COVID-19 pandemic has emerged as the most significant public health crisis of the 21st century. As of the end of January 2023, global confirmed cases have exceeded 670 million, with a domestic cumulative total of 10.24…
- Conditions
- COVID-19 Pandemic, Diabetes, Hypertension, Cardiac Disease
- Trial name
- NCT06231225
- Testing
- Incentive Spirometer respiratory training
- Volunteers
- 100 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
COVID-19
Immunogenicity and Safety of Booster Immunization of COVID-19 Vaccine (Vero Cell), Inactivated (Omicron Variant) in Healthy People Aged 18 Years and Above
This is a randomized, double-blind, active-controlled Phase Ⅲ clinical trial, as well as an immuno-bridging clinical trial by parallel testing previous serum after primary immunization of COVID-19 vaccine (Vero cell), inactivated…
- Trial name
- NCT05381350
- Testing
- COVID-19 Vaccine (Vero cell), Inactivated (Omicron variant), COVID-19 Vaccine (Vero cell), Inactivated (CZ strain)
- Where
- China
- Volunteers
- 1,750 people, healthy volunteers welcome
- Sponsor
- Sinovac Research and Development Co., Ltd.
Olfactory Dysfunction, Covid19
Acupuncture for Olfactory Dysfunction in Infected COVID-19 Patients
In this a 12-week, single blinded, randomized sham controlled, and cross-over clinical trial. It will be conducted to explore the safety and efficacy of acupuncture for olfactory dysfunction in infected COVID-19 patients in Hong…
- Trial name
- NCT04959747
- Testing
- acupuncture
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- Hong Kong Baptist University
Communication Research
Project Resurgence Communication Trial
Randomized, double-blind, of standard of care vs additional communication and factorial design of intervention letter vs. control letter and EHR vs mail delivery mechanism in patients who canceled visits and did not reschedule…
- Trial name
- NCT04418947
- Testing
- Communication type
- Where
- United States
- Volunteers
- 11,120 people
- Sponsor
- University of Pennsylvania
Covid19
Geriatric Care for Older People Hospitalised for COVID-19
Current COVID-19 pandemic implies regular treatment adaptation by physician, according to scientific publication evolution. Older adults are particularly affected by COVID-19, with the higher severe form prevalence and the higher…
- Trial name
- COVAGERT (NCT04947943)
- Where
- France
- Volunteers
- 230 people
- Sponsor
- University Hospital, Montpellier
COVID-19
Reducing COVID-19 Related Hospital Admission in Elderly by BCG Vaccination
Bacillus Calmette-Guérin (BCG) vaccine not only protects against tuberculosis, but has also been shown to induce protection against various infections with a viral aetiology, leading to significant reductions in morbidity and…
- Trial name
- NCT04417335
- Testing
- BCG vaccine
- Where
- 2 sites in Netherlands
- Volunteers
- 2,014 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
COVID-19
Methodist Health System COVID-19 Patient Registry
This is a prospective cohort observational registry study that will include data on all patients who are treated at MHS facilities for COVID-19.
- Trial name
- NCT04477889
- Testing
- Treatment for COVID-19
- Where
- United States
- Volunteers
- 550 people
- Sponsor
- Methodist Health System
Covid19
Characterisation of the Immune Response to SARS-CoV-2 / COVID-19
Emerging clinical details of the current SARS-CoV-2 pandemic have illustrated that there are multiple clinical presentations and outcomes of this viral infection.
- Trial name
- NCT04729452
- Testing
- blood test
- Where
- United Kingdom
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Cwm Taf University Health Board (NHS)
COVID-19
A Study of Efficacy and Safety of Azvudine vs. Nirmatrelvir-Ritonavir in the Treatment of COVID-19 Infection
The COVID-19 pandemic has become a major public health challenge, and the treatment options for the disease are currently limited.
- Trial name
- NCT05697055
- Testing
- Azvudine, Nirmatrelvir-Ritonavir
- Where
- China
- Volunteers
- 410 people
- Sponsor
- Shandong Provincial Hospital
SARS-CoV-2 Acute Respiratory Disease, SARS-CoV-2 Sepsis
The Corona Study of Middle Norway
CUT COVID is a cohort study establised to collect information on patients hospitalized because or with infection by SARS-CoV-2. The cohort data includes clinical data and biological samples from multiple timepoints during…
- Conditions
- SARS-CoV-2 Acute Respiratory Disease, SARS-CoV-2 Sepsis, SARS CoV 2 Infection
- Trial name
- CUT COVID-19 (NCT05638178)
- Testing
- No intervention
- Where
- 5 sites in Norway
- Volunteers
- 223 people
- Sponsor
- St. Olavs Hospital