Clinical trials: SARS CoV-2
COVID-19
Safety in Convalescent Plasma Transfusion to COVID-19
There is currently no specific vaccine or treatment to treat critically ill patients with COVID-19. Different therapies are still under investigation and are use in different health institutions, however, a significant proportion…
- Trial name
- NCT04333355
- Testing
- Convalescent Plasma
- Where
- Mexico
- Volunteers
- 12 people
- Sponsor
- TecSalud Investigación Clínica
SARS-CoV-2 Infection, Covid19
Safety and Immunogenicity of an Inactivated Vaccine Against COVID-19 in Medical Workers
With the unprecedented morbidity of the COVID-19 pandemic, the vaccine effectiveness needs to be assessed across diverse populations.
- Trial name
- NCT04795414
- Testing
- SARS-CoV-2 Vaccine(Vero Cell), Inactivated
- Where
- China
- Volunteers
- 1,370 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
COVID-19
Effectiveness of Remedesvir in COVID-19 Patients Presenting at Mayo Hospital Lahore
Currently, several drugs including Remdesivir, hydroxychloroquine, chloroquine, ritonavir+lopinavir, Tocilizumab, Arbidol and interferon are under randomised controlled trials (RCTs) for efficacy and/or safety evaluations in…
- Trial name
- NCT04871633
- Testing
- Remdesivir, Conventional
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- King Edward Medical University
Chronic Kidney Disease 5D, Chronic Kidney Disease 5T
Humoral and Cellular İmmune Response to SARS-CoV-2 mRNA BNT162b2 Vaccine in Children With Chronic Kidney Diseases
Coronavirus 2019 (COVID-19) infection is associated with higher morbidity and mortality in adult patients on dialysis, and kidney transplant recipients (KTRs).
- Trial name
- NCT05465863
- Testing
- SARS-CoV-2 mRNA BNT162b2 vaccine (Pfizer-BioNTech®)
- Where
- 6 sites in Turkey (Türkiye)
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Post-Acute COVID19 Syndrome, Long COVID
Exercise Intervention Using mHealth in Patients With Post-Acute COVID-19 Syndrome: a Randomized Clinical Trial
Post-Acute Syndrome COVID-19 is a disease resulting from infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
- Conditions
- Post-Acute COVID19 Syndrome, Long COVID, Post COVID-19 Condition
- Trial name
- COVIDReApp (NCT05725538)
- Testing
- COVIDReApp Group, Control Group
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- University of Cadiz
COVID-19
YKL -40 as New Biomarker in COVID -19 Patients
The coronavirus disease-2019 (COVID-19)is a pandemic disease caused by SARS -COV-2 which belongs to the β-coronavirus family . The majority of affected individuals exhibit no or mild to moderate symptoms, but up to 15% of…
- Trial name
- NCT05137509
- Testing
- Computerized Tomography
- Volunteers
- 100 people
- Sponsor
- Assiut University
COVID-19
Hydroxychloroquine vs. Azithromycin for Hospitalized Patients With Suspected or Confirmed COVID-19
This study will compare two drugs (hydroxychloroquine and azithromycin) to see if hydroxychloroquine is better than azithromycin in treating hospitalized patients with suspected or confirmed COVID-19.
- Trial name
- HAHPS (NCT04329832)
- Testing
- Hydroxychloroquine, Azithromycin
- Where
- 2 sites in United States
- Volunteers
- 85 people
- Sponsor
- Intermountain Health Care, Inc.
COVID-19
A Safety and Tolerability Study of BDB-001 in Mild, Moderate COVID-19 Patients
This open, multi-center, multiple ascending dose study was designed to evaluate the safety, tolerability, preliminary efficacy and PK/PD of BDB-001 injection in patients with mild, or general COVID-19.
- Trial name
- NCT05075304
- Testing
- BDB-001 injection
- Where
- 4 sites in China
- Volunteers
- 18 people
- Sponsor
- Staidson (Beijing) Biopharmaceuticals Co., Ltd
Immunocompromised Patients
A Real-World Study of Anti-SARS-CoV-2 Monoclonal Antibodies in Prophylaxis and Curative of Covid-19 (COVIMAB)
Absence of anti-SARS-CoV-2 vaccine response or insufficient vaccine response may occur in immunocompromised patients. Being at high risk of a severe form of Covid-19, they may be eligible to receive recombinant anti-SARS-CoV-2…
- Trial name
- COVIMAB (NCT05439044)
- Testing
- Data collection
- Where
- France
- Volunteers
- 4,235 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
SARS (Severe Acute Respiratory Syndrome)
Quercetin In The Treatment Of SARS-COV 2
In 1937, Albert Szent-Gyorgyi received a Nobel Prize for discovering vitamin C and flavonoids, as well as for exploring their biochemical properties.
- Trial name
- QUERCOV (NCT04853199)
- Testing
- Quercetin
- Where
- 2 sites in Tunisia
- Volunteers
- 200 people
- Sponsor
- Hôpital Universitaire Sahloul
Covid19, SARS-CoV Infection
Caracterisation of COVID-19 Patients Hospitalized in Infectious Disease Department
The main objective of this cohort is to characterize COVID-19 patients hospitalized in infectious disease department. The collection of clinical and biological data from start of hospitalization to long-term follow up will…
- Trial name
- NCT04779021
- Testing
- Hospitalisation for SARS-COV2 infection
- Where
- 2 sites in France
- Volunteers
- 1,300 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Leukemia, Acute, Covid19
Clinical Characteristics of Patients With Leukemia and COVID-19
The purpose of this study is to describe the main clinical characteristics of patients with de novo acute lymphoblastic leukemia treated inside the third level hospitals converted to Coronavirus disease 2019 (COVID-19) attention…
- Conditions
- Leukemia, Acute, Covid19, Leukemia, Lymphoblastic
- Trial name
- NCT04745416
- Where
- 2 sites in Mexico
- Volunteers
- 30 people
- Sponsor
- Hospital General de Mexico
COVID-19, COVID Long-Haul
Comprehensive Imaging Exam of Convalesced COVID-19 Patients
COVID-19 is a systemic inflammatory disease involving many organs including the lungs, vascular system liver and myocardium that lead to severe pathologies.
- Trial name
- NCT05920616
- Testing
- Magnetic Resonance Imaging, Ultra-High Resolution Computed Tomography (CT) Scan
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- Johns Hopkins University
D001452
Balneotherapy and Anxiety During SARS-CoV-2 Pandemic
Investigators will measure the level of anxiety and fear of Covid during the balneological treatment in patients. They are interested in the effect of general trust and resilience on the level of anxiety state.
- Trial name
- TRATACO (NCT05249855)
- Testing
- Psychological measurement
- Volunteers
- 400 people
- Sponsor
- University of Bucharest
COVID-19
Part Two of Novel Adoptive Cellular Therapy With SARS-CoV-2 Specific T Cells in Patients With Severe COVID-19
The overall objective of this project is to develop an emergent treatment protocol using adoptive T-cell therapy for the treatment of severe COVID-19.
- Trial name
- NCT04457726
- Testing
- SARS-CoV-2 Specific T Cells
- Where
- 5 sites in Singapore
- Volunteers
- 18 people
- Sponsor
- KK Women's and Children's Hospital
COVID-19
Heterologous Boost Immunization with Ad5-nCoV After Three-dose Priming with an Inactivated SARS-CoV-2 Vaccine
This is an open-label, randomized, parallel-controlled clinical trial to evaluate the safety and immunogenicity of heterologous prime-boost immunization with an aerosolized (Ad5-nCoV-IH) or intramuscular (Ad5-nCoV-IM) Ad5-nCoV…
- Trial name
- NCT05303584
- Testing
- Ad5-nCoV-IH, Ad5-nCoV-IM, CoronaVac
- Where
- China
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- Jiangsu Province Centers for Disease Control and Prevention
Covid19
COVID 19 Preventive Measures Among Mansoura Nursing Students
This study aims to identify nursing students knowledge gaps, risk perceptions and adherence to COVID 19 preventive measures during written exam period and In addition due to the possibility of being infected with COVID-19 during…
- Trial name
- NCT04473547
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Mansoura University
COVID-19, Vaccine Reaction
Evaluation of Inactivated Vaccine in Healthy Adults Against Coronavirus Disease of 2019 (COVID-19)
In this phase 1 study, the inactivated virus vaccine National Research Centre (NRC) Vaccine-101 (VACC-101) will be investigated for its safety and immunogenicity in healthy volunteers with the aim of providing effective and safe…
- Conditions
- COVID-19, Vaccine Reaction, Vaccine Adverse Reaction
- Trial name
- NCT05128721
- Testing
- Covi Vax
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Research Centre, Egypt
COVID-19, Acute Respiratory Failure
COVID Cohort Study
The novel SARS-CoV-2 virus has quickly spread worldwide, with substantial morbidity and mortality. There is very limited understanding of the short- and longer-term inflammatory/immunological and clinical course.
- Trial name
- NCT04393155
- Testing
- COVID-19+ observational
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Vermont
COVID-19, SARS-CoV-2
Investigation the Effect of Montelukast in COVID-19
Small molecule inhibitors have previously been investigated in different studies as possible therapeutics in the treatment of SARS-CoV-2.
- Trial name
- NCT04718285
- Testing
- Montelukast Oral Tablet, Montelukast plus Favicovir (Favipiravir), Favicovir (Standard Treatment)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 380 people
- Sponsor
- Bahçeşehir University