Clinical trials: Running, open to volunteers
Stress Urinary Incontinence (SUI)
Managing Impact-related Leakage During Exercise Using Intravaginal Support
The goal of this study is to evaluate the effectiveness of using a regular menstrual tampon or a Uresta pessary to reduce urine leakage associated with running-induced stress urinary incontinence (RI-SUI) in females aged 18 and…
- Trial name
- MILES (NCT07103161)
- Testing
- Uresta bladder support device, Sportex regular tampon
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Ottawa
Venezuelan Equine Encephalomyelitis
Safety and Immunogenicity Study of Venezuelan Equine Encephalomyelitis (VEE) Vaccine as Booster Vaccine in Adults
The purpose of this study is to evaluate the safety and immunogenicity of VEE vaccine, C-84, TSI-GSD 205, Lot 7, Run 1, and collect data on the incidence of occupational VEE infection in vaccinated personnel.
- Trial name
- VEE (NCT03531242)
- Testing
- 0.5 mL Inactivated, Dried, C-84, TSI-GSD 205, Lot 7, Run 1
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Exercise, Cardiac Function
Acute Cardiac Effects of Ultra-Trail Running
This prospective observational study aims to investigate the acute cardiovascular effects of ultra-endurance running using comprehensive echocardiographic assessment combined with biological analyses.
- Conditions
- Exercise, Cardiac Function, Echocardiography
- Trial name
- ULTRA-ECHO (NCT07753694)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
The Effects of Sodium Bicarbonate Supplementation on Endurance Performance in Recreational Female Runners
Sodium Bicarbonate Intake on Endurance Performance
Sodium bicarbonate (SB) is one of the ergogenic aids that enhance short-duration, high-intensity sports performance by improving the buffering system.
- Trial name
- NCT06826222
- Testing
- Sodium Bicarbonate (NaHCO3), Sodium Chloride
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Long Distance Running
Immediate, Residual, and Cumulative Effects of Fartlek, Hill Circuit, and Roll-On Training in Long-Distance Runners
This randomized controlled trial will compare Fartlek, hill circuit, and roll-on training in well-trained long-distance runners.
- Trial name
- IRCT-LDR (NCT07784140)
- Testing
- Fartlek training, Hill Circuit, Roll-On
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Debre Markos University
Skin Graft Scar
Surgical Outcomes of Simple Interrupted Versus Running Epidermal Sutures in Full-thickness Skin Graft Placement
The study hypothesis is that the use of running epidermal sutures in full-thickness skin graft (FTSG) placement for patients undergoing dermatologic surgery (Mohs micrographic surgery or excision) is non-inferior to the use of…
- Trial name
- NCT06233812
- Testing
- Simple interrupted suturing technique, Running suturing technique
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Breast Cancer, Leptomeningeal Disease
Trial of Therapies With IT cDC1s Combined w/ IT Trastuzamab for Her+ or IT Nivolumab for Her- BC LMD
The purpose of this study is to learn about the effects of the study treatment, Dendritic Cell Vaccine (DCV), in combination with trastuzumab or nivolumab to confirm the highest dose of the study treatment that can be given…
- Trial name
- NCT07694986
- Testing
- cDC1 Vaccine, Trastuzumab, Nivolumab
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Gait, Balance
Sensor Ankle Brace for Special Operations Rehabilitation
The primary purpose of this study overall is to validate a modified version of a commercially available ankle brace. Inertial measurement unit sensors will be incorporated into an existing ankle brace ("sXAB") by TayCo Brace…
- Conditions
- Gait, Balance, Biomechanical Data, Postural Control
- Trial name
- NCT07776223
- Testing
- Sensor-enabled Athletic X Ankle Brace (sXAB)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Indiana University
The Focus is to Investigate Effect of an Educational Video on Fecundity Knowledge Among Young Adults
Young Adults' Fecundity Knowledge and Fertility Intentions and Reproductive Behavior
This RCT investigates the impact of an educational video on fecundity knowledge among young adults. The video discusses several risk factors associated with fecundity, such as age and smoking.
- Trial name
- NCT06631950
- Testing
- Educational intervention
- Where
- 2 sites in Denmark, Norway
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Merkel Cell Carcinoma
Phase II Study of Peptide Receptor Radionuclide Therapy in Combination With Immunotherapy for Patients With Merkel Cell Cancer
The purpose of this study is to find out what effects an immunotherapy drug, called pembrolizumab, combined with a radioactive drug, called lutetium Lu 177 dotatate (Lutathera®) have on patients with Merkel cell carcinoma.
- Trial name
- iPRRT (NCT05583708)
- Testing
- Pembrolizumab, Lutetium Lu 177 dotatate
- Where
- 4 sites in United States
- Volunteers
- 18 people
- Sponsor
- Weill Medical College of Cornell University
Healthy
Does Listening to Music Alter the Running Mechanics?
The purpose of this study is to determine whether in healthy subjects listening to music while running influences the ground pressure forces, the vertical loading and, overall, the running biomechanics.
- Trial name
- NCT03506282
- Testing
- Running while listening to a traffic audio track, Running with music at moderate volume, Running with music at moderate-to-high volume
- Where
- 2 sites in Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Caesarean Scar Niche
Niche Investigated: Closure of Hysterotomy & Evaluation of 3 Suturing Techniques (Running, Interrupted, and Locked)
This study aims to explore the impact of three different suturing techniques (Running, Interrupted \& Locked) that used to close the uterine incision at the cesarean section on the formation of a cesarean scar niche
- Trial name
- NCT06695793
- Testing
- Interrupted Sutures, Locked Sutures, Running Continuous Sutures
- Where
- 5 sites in Egypt
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Cairo University
Injury Prevention
Changing Youth Narratives on Firearm Violence ("Run It Up") Intervention
The Run It Up project is an experimental, theory-driven effort to address a specific connection between structural factors, youth identity development, and violence, where structural factors in some communities may limit…
- Trial name
- NCT06940362
- Testing
- Changing narrative intervention modules
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- George Washington University
Heart Failure
The Value of a Simple Tool for the Early Detection of Decompensated Heart Failure in People Over 55 on Réunion Island: A Preliminary Study in Hospitals (DEPIST'IC-RUN)
The goal of this study is to assess the discriminatory power of a previously developed tool for detecting decompensated heart failure-which includes, in particular, clinical signs-in a population of patients hospitalized in…
- Trial name
- DEPIST'IC-RUN (NCT07673562)
- Testing
- Early Detection Questionnaire
- Where
- 3 sites in Reunion
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Scarring
Outcomes of Running Locking Suture vs Standard Running Suture in Surgical Wounds
When patients have surgery on the head and face, stitches are the standard way to close the wound. Wounds always result in a scar, but doctors are always looking for ways to reduce scarring.
- Trial name
- NCT06288009
- Testing
- Running locking suture, Standard running suture
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Colonoscopy (Procedure)
Use of GI Genius™ XR Software in Virtual Reality Headset During Routine Colonoscopy
This pilot study will evaluate the usability and safety of software GI Genius™ XR in the Apple Vision Pro™ virtual reality headset when used in conjunction with the GI Genius™ system during routine screening and surveillance…
- Trial name
- NCT07220174
- Testing
- software GI Genius™ XR on headset
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cosmo Artificial Intelligence-AI Ltd
Exercise Physiology, Nutritional Supplementation
Effects of Pre-Run Nutritional Supplements During a Fixed-Pace 5 km Treadmill Run
This study will examine how three commonly used pre-run nutritional supplements-caffeine, L-citrulline, and an exogenous ketone supplement-affect physiological and perceptual responses during a fixed-pace 5 km treadmill run in…
- Trial name
- NCT07854223
- Testing
- Caffeine, L-Citrulline, Exogenous Ketone (Beta-Hydroxybutyrate)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Congenital Heart Diseases, Cardiac Diseases
An International Multicenter, Multivendor Evaluation of the Free-Running Framework for Cardiac Function
This project aims to evaluate a new cardiac MRI technique called the Free-Running Framework (FRF), which could simplify and accelerate the process of acquiring cardiac images.
- Trial name
- FAST-CMR (NCT07613398)
- Where
- 20 sites in United States, Australia and 8 more
- Volunteers
- 300 people
- Sponsor
- Matthias Stuber
Physical Activity, Physical Activity Intensity
Effects of Polarized and Threshold Intensity Distribution Models on Race Time and Body Composition in Recreational Runners Aged 20-45 Years.
This study aims to compare the effects of two intensity distribution training (TID) models-polarized and threshold-on 5-km race time and body composition in recreational runners aged 20 to 45 years.
- Conditions
- Physical Activity, Physical Activity Intensity, Physical Activity in Adults, Running
- Trial name
- NCT07498608
- Testing
- Polarized intensity distribution model, Threshold intensity distribution model
- Where
- Colombia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Pedagogica Nacional, Colombia
Advanced Malignancies
Study of PM54 in Combination With Immunotherapy in Adult Participants With Advanced Malignancies
The main purpose of the study is to evaluate the safety, tolerability and recommended dose of PM54 in combination with pembrolizumab.
- Trial name
- NCT07644039
- Testing
- Pembrolizumab, PM54
- Where
- 11 sites in United States, Spain
- Volunteers
- 119 people
- Sponsor
- PharmaMar