Clinical trials: Rumination
Schizophrenia, Depressive Disorder, Major
Rescuing the Ruminating Brain: Identifying Biomarkers of Rumination and Mindfulness Through Concurrent EEG and Functional Magnetic Resonance Imaging (fMRI) Studies of Schizophrenia and Depression
The investigators will acquire simultaneous EEG and fMRI data from Veterans with depression and schizophrenia and mentally healthy Veterans to assess early sensory responses, context updating, and responses to emotional images.
- Trial name
- NCT03758495
- Testing
- Electroencephalography (EEG) and Magnetic Resonance Imaging (MRI)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Rumination, Chronic Pain
Modulation of Cortical Brain Activity During Attentional Control
The goal of this study is to determine whether an open-loop sham neurofeedback system can effectively modulate EEG alpha rhythms, which are associated with attentional control.
- Conditions
- Rumination, Chronic Pain, Fibromyalgia
- Trial name
- NCT06748976
- Testing
- Control
- Where
- Argentina
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- National Council of Scientific and Technical Research, Argentina
Study Protocol Feasibility, Non Clinical Anxiety
Effects of Darkness Retreat: a Pilot Study
The primary goal of this pilot study is to test the feasibility and safety of a research protocol for a voluntary darkness retreat.
- Conditions
- Study Protocol Feasibility, Non Clinical Anxiety, Non Clinical Worry, Non Clinical Rumination
- Trial name
- NCT07429617
- Testing
- Darkness Retreat - Several Days of Seclusion in Complete Darkness
- Where
- 2 sites in Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Fear of Childbirth, Rumination
Affirmation-Based Podcast Education for Fear of Childbirth and Rumination in Pregnant Women
This study examined the effect of affirmation-based podcast training on fear of childbirth and ruminative thoughts among pregnant women.
- Conditions
- Fear of Childbirth, Rumination, Pregnancy
- Trial name
- NCT07590921
- Testing
- Affirmation-based podcast training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istinye University
Cancer Survivors
Empowerment Program for Cancer Survivors
This study aims to decrease cancer survivors' intrusive ruminative thoughts and cancer-related fatigue and increase their purposive ruminative thoughts and psychological resilience.
- Trial name
- NCT05768984
- Testing
- Empowerment program
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Sinem Ocalan
Emotions, Rumination
Neural Predictors of Social Emotion Regulation Training
The purpose of this study is to investigate the basic psychological and neural mechanisms underlying the social regulation of emotion - that is, how one person's actions can impact, or regulate - the emotions of another person …
- Trial name
- NCT03487081
- Testing
- Social regulation, Self regulation
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Columbia University
Mild to Moderate Depression
EMI Therapy for Depression in Hong Kong
To determine if a two-week ecological momentary intervention (two EMA + one EMI daily) as augmentation to treatment as usual would reduce depressive symptoms, rumination levels, and functioning in subjects with mild to moderate…
- Trial name
- NCT06430476
- Testing
- EMI, EMA
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Older Adults (65 Years and Older)
The Effect of Psychoeducation Program Applied to Older Adults Based on Psychosocial Development Theory on Self-critical Rumination, Self-esteem and Psychological Well-being
The aim is to examine the effect of a psychoeducation program based on the Psychosocial Development Theory applied to older adults on self-critical rumination, self-esteem, and psychological well-being, as well as the…
- Trial name
- NCT07274592
- Testing
- Psychoeducation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Depressive Disorder, Depression
Mindfulness Based Emotion Regulation Therapy in the Treatment of Depressive Rumination
In this study the investigators are examining the neuronal processes of a mindfulness based emotion regulation training for reducing depressive rumination.
- Conditions
- Depressive Disorder, Depression, Rumination
- Trial name
- NCT04560192
- Testing
- Mindfulness based Emotion regulation therapy (MBERT) - Treatment as usual (TAU), Treatment as usual (TAU) - Mindfulness based Emotion regulation therapy (MBERT)
- Where
- Germany
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Anxiety, Depression
Metacognitive Bibliotherapy for Anxiety, Depression, and Metacognitions in University Students
This study tests whether reading a structured self-help book (bibliotherapy) can reduce anxiety, depression and stress and change unhelpful thinking patterns in medical and health-sciences students.
- Conditions
- Anxiety, Depression, Stress (Psychology)
- Trial name
- NCT07627139
- Testing
- Zihninde Çok Kuran İnsanlar için Salma Rehberi, Çapa Atmak
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Istanbul Nisantasi University
Suicidal Ideas, Suicidal Ideation
Exploratory Analysis of Interpersonal and Intrapersonal Psychological Processes Implied in Risk-taking and Suicidal Behaviors, in Adult and Adolescent At-risk
In a recent report, Santé Publique France (2023), reported that 4.2% of 18-85 year-olds had thought about suicide in the last 12 months, and 6.8% had attempted suicide in their lifetime and 0.5% in the last year.
- Conditions
- Suicidal Ideas, Suicidal Ideation, Risk-taking
- Trial name
- RISKY (NCT06921226)
- Testing
- Psychological Processes, Risk-taking variables, Suicidal ideation and behavior
- Where
- 3 sites in France
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Metropole Savoie
Major Depressive Disorder (MDD), Rumination
Neurobiological Mechanisms of Pathological Rumination and Effects of Aripiprazole
This randomized, single-blind (assessor-blind) controlled trial aims to investigate the efficacy of aripiprazole as an augmentation strategy for treating pathological rumination in patients with major depressive disorder (MDD).
- Trial name
- NCT06937476
- Testing
- Escitalopram, Aripiprazole 5mg
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Central South University
Depression, Anxiety, Self-Injurious Behavior
Brief App-based Mood Monitoring and Mindfulness Intervention for First-year College Students
The investigators examined whether brief, app-based interventions were helpful in alleviating mental health symptoms during the transition to college.
- Trial name
- NCT06348277
- Testing
- Mindfulness plus mood monitoring, Mood monitoring
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Lawrence University
Rumination Syndrome
Baclofen for Children With Rumination Syndrome
The goal of this clinical trial is to learn about baclofen in pediatric patients with rumination syndrome. The main question it aims to answer is whether baclofen is effective in treating children with rumination syndrome.
- Trial name
- NCT05975684
- Testing
- Baclofen
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Repetitive Negative Thinking
Feasibility and Preliminary Efficacy of a Web-Based Self-Help Program for College Students
The goal of this pilot study is to test the feasibility and preliminary efficacy of the repetitive negative thinking (RNT) focused web-based self-help program in college students.
- Trial name
- NCT06192056
- Testing
- RNT Focused Web- Based Self-Help Program
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Halic University
Loneliness, Worry, Rumination, Health Anxiety, Depression, Anxiety
Loneliness During the NPIs for the COVID-19 Pandemic in Norway: Risk Factors and Associations With Psychopathology
The present study of loneliness during the COVID-19-related NPIs is part of a larger project aiming to investigate psychological reactions and symptoms associated with the current and ongoing governmental initiatives in place in…
- Trial name
- NCT04365881
- Testing
- Cross-sectional observational study
- Where
- Norway
- Volunteers
- 10,084 people, healthy volunteers welcome
- Sponsor
- Modum Bad
Major Depressive Disorder
Network Neurofeedback Using 7-Tesla MRI to Reduce Rumination Levels in Depression
Patients with major depressive disorder (MDD) exhibit increased levels of rumination (i.e. repetitive thinking and focus on negative mood states) which have been found to increase the risk of depressive relapse.
- Trial name
- NCT05933148
- Testing
- Siemens 7T MRI
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Anxiety
The Effect of Emotion Recognition and Empathy Focused Education Program Applied to Earthquake Survivors on Anxiety, Rumination and Post-traumatic Growth Levels of Children
Earthquakes cause increased mental health problems in the communities they hit. Few attempts have been made to develop effective psychological care strategies for earthquake survivors.
- Trial name
- NCT05815966
- Testing
- The effect of emotion recognition and empathy focused education program
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Gaziantep Islam Science and Technology University
Depression
Working Memory Training for Dysphoric Students
Depression is associated with impairments in executive functions, including working memory (WM) which is needed to maintain and manipulate goal-relevant information.
- Trial name
- NCT02184481
- Testing
- Working memory training
- Where
- Netherlands
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Depression
Influence of Expectations on Rumination
The study tries to identify whether positive expectations, induced with an active placebo nasal-spray, have effects on rumination.
- Trial name
- NCT03869424
- Where
- Germany
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg