Clinical trials: Root Canal Obturation
Symptomatic Irreversible Pulpitis (SIP), Post Operative Pain After Root Canal Therapy
Effects of Irrigation Activation and Obturation Techniques on Pain After Root Canal Treatment
This randomized controlled clinical trial aimed to compare postoperative pain and analgesic use following single-visit root canal treatment performed using different final irrigation activation and root canal obturation…
- Trial name
- NCT07882368
- Testing
- Conventional Needle Irrigation, Sonic Irrigation Activation, Cold Lateral Condensation
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Biruni University
Dental Pulp Diseases, Dental Pulp Necrosis
Nanodiamond Modified Gutta Percha (NDGP) Composite for Non-surgical Root Canal Therapy (RCT) Filler Material
Non-surgical root canal therapy (RCT) represents a standard of treatment that addresses infected pulp tissue in teeth and protects against future infection while preserving the tooth for the patient for mainly cosmetic purposes.
- Conditions
- Dental Pulp Diseases, Dental Pulp Necrosis, Nerve Root Pain Nec
- Trial name
- NCT02698163
- Testing
- Nanodiamond reinforced Gutta Percha, Gutta Percha
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, Los Angeles
Periapical Periodontitis, Chronic Periapical Periodontitis
Evaluation of Bone Healing After Obturation With Dia-Root Bio Sealer (Calcium Silicate-based Sealer CSBS) Using Three Obturation Techniques
The study aims to evaluate the efficiency of using a Calcium silicate-based sealer (CSBS) with different obturation techniques in treating root canals with apical periodontitis in single visit. Evaluating: 1.
- Conditions
- Periapical Periodontitis, Chronic Periapical Periodontitis, Periapical Abscess, Pulp Necrosis, Apical Periodontitis
- Trial name
- CSBS (NCT07684014)
- Testing
- Dia-Root Bio Sealer, Single cone (SC) Obturation technique, Warm Vertical compaction (WVC) technique
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Ain Shams University
Postoperative Pain After Endodontic Treatment, Oral Health-Related Quality of Life
Effects of Different Root Canal Filling Materials and Irrigation Agitation Techniques on Postoperative Pain in Teeth With Irreversible Pulpitis: A Randomized Clinical Trial
This clinical study is designed to evaluate the effects of different irrigation agitation techniques and root canal sealers on postoperative pain and oral health-related quality of life in patients with symptomatic irreversible…
- Conditions
- Postoperative Pain After Endodontic Treatment, Oral Health-Related Quality of Life, Symptomatic Irreversible Pulpitis, Endodontic Treatment
- Trial name
- NCT07859384
- Testing
- XP-Endo Finisher, EDDY, Passive Ultrasonic Activation
- Where
- Turkey (Türkiye)
- Volunteers
- 324 people
- Sponsor
- Ankara University
Endodontic Treatment
A Study to Assess the Clinical Success of Root Canal Treatment Using Novel Obturation Material.
The goal of this study is prospective, single-arm, non-randomized controlled trial to test the effectiveness, safety and performance of a novel dental obturation material. The main question sit answers is 1.
- Trial name
- NCT06312085
- Testing
- Endofill
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Lumendo AG
Postoperative Pain, Endodontic Disease
Post-endodontic Pain Survey
As part of root canal treatment, canals should be sealed to prevent further contaminations. There are multiple accepted techniques to fill-obturate canals. In the past, different obturation techniques have been compared.
- Conditions
- Postoperative Pain, Endodontic Disease, Obturation
- Trial name
- NCT04462731
- Testing
- Non-surgical root canal treatment filled with WVT, Non-surgical root canal treatment filled with SBT
- Volunteers
- 194 people
- Sponsor
- Ya-Hsin Yu, DDS, MS
Root Canal Obturation
Measurement of the Clinical and Radiological Performance Impact of the Root Canal Treatment With BioRootTM RCS.
The aim of this retro-prospective Post-Market Clinical Follow-Up (PMCF) study is to collect long term clinical and safety data on root canal obturation after treatment, or retreatment, by BioRootTM RCS.
- Trial name
- BioRoot RCS (NCT05247138)
- Testing
- BioRootTM RCS
- Where
- 9 sites in France
- Volunteers
- 142 people
- Sponsor
- Septodont
Root Canal Obturation, Apical Periodontitis
Evaluation of Postoperative Pain and Lesion Healing in Periapical Lesion-Affected Teeth Obturated With Different Root Canal Sealers
The root canal treatment of volunteers with asymptomatic apical periodontitis will be completed using TotalFill BC and AH Plus root canal sealers, and postoperative pain as well as healing will be comparatively evaluated through…
- Trial name
- NCT07307807
- Testing
- AH Plus and PAI 2-3, AH Plus and PAI 4, TotalFill BC Sealer and PAI 2-3
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Ankara Yildirim Beyazıt University
Root Canal Treatment
On Previously Root Canal-treated Patients Using an AI Program, Detect the Accuracy of it in the Detection of Root Canal Obturation Quality on CBCT Compared With Conventional PA Radiography, e.g., Voids, Length of Obturation, and Density, and Then do Retreatment if Any Failure is Recorded.
aims to evaluate the accuracy of clinicians (conventional radiograph) compared to cone beam computed tomography (CBCT) and artificial intelligence software's ability to identify the quality of root canal obturation.
- Trial name
- AI (NCT07056998)
- Testing
- root canal retreatment
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Tala Ghassan Hassan Odeh
Postoperative Pain
The Effect of Different Obturation Techniques on Postobturation Pain in Single-Visit Root Canal Treatment
The goal of this prospective clinical randomized study is to evaluate the effect of different obturation techniques on postobturation pain in single-visit root canal treatment in 18-60 years old patient who present no systemic…
- Trial name
- NCT06146894
- Testing
- Single obturation technique (Bioceramic Sealer), lateral condensation technique (Bioceramic Sealer), Warm Vertical condensation technique (Bioceramic Sealer)
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Dental Pulp Disease, Endodontically Treated Teeth
Post Operative Sensitivity of MTA Obturation
The aim of this study was to investigate the difference in postoperative pain caused by different root canal sealers in patients with irreversible pulpitis symptoms and no apical lesions.
- Conditions
- Dental Pulp Disease, Endodontically Treated Teeth, Endodontic Disease
- Trial name
- NCT06795282
- Testing
- MTA
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Postoperative Pain
Postoperative Pain After the Removal of Root Canal Filling Material
The aim of this study was to evaluate the intensity and duration of postoperative pain after the removal of root canal filling material in retreatment procedures of upper incisor teeth with chronic apical periodontitis, using…
- Trial name
- NCT02905773
- Testing
- root canal therapy, root canal retreatment
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Asymptomatic Apical Periodontitis
Postoperative Pain and Quality of Life Following Root Canal Treatment With Two Different Sealers
This study compares two different root canal sealers, AH Plus and BioRoot Flow, to determine whether the type of sealer used during root canal treatment affects pain after treatment and oral health-related quality of life.
- Trial name
- NCT07884799
- Testing
- AH Plus, BioRoot Flow
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Karadeniz Technical University
Periapical Diseases, Pulp Necroses
Cell-free Autologous Regenerative Endodontics Treatment for Teeth With Periapical Lesions (CARETT)
Conventional endodontic treatment has been the treatment of choice for the management of signs and symptoms of mature permanent teeth with pulpal necrosis and periapical lesion with predictable and favorable results.
- Trial name
- CARETT (NCT05305417)
- Testing
- Autologous Regenerative Endodontic Treatment, Conventional Root Canal Treatment
- Volunteers
- 228 people
- Sponsor
- Universidad de Valparaiso
Tooth Discoloration Following Root Canal Treatment
TOOTH DİSCOLORATİON AFTER ROOT CANAL TREATMENT WİTH AH PLUS AND BİOROOT RCS
he purpose of this clinical study is to compare tooth color changes after root canal treatment using two different root canal sealers, AH Plus and BioRoot RCS, in upper front teeth.
- Trial name
- NCT07849296
- Testing
- AH Plus Root Canal Sealer, BioRoot RCS Root Canal Sealer
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Retreatment, Root Canal Retreatment
Comparison of the Efficacy of Calcium Hydroxide With Silver Nanoparticle and Conventional Calcium Hydroxide Intra Canal Medications on Post-Operative Pain in Symptomatic Root Canal Treatment Failure Cases:
The aim of this study is to measure and compare the effectiveness of nanosilver combined calcium hydroxide and conventional calcium hydroxide intracanal medications in reducing postoperative pain in patients with Symptomatic Root…
- Conditions
- Retreatment, Root Canal Retreatment, Nonsurgical Retreatment, Endodontic Failure
- Trial name
- CSNIMSRRT (NCT04213716)
- Testing
- silver nano particulate solution mixed with calcium hydroxide powder, conventional calcium hydroxide
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Root Canal Obturation
Pain After Root Canal Obturation With Sealer Containing or Not 1% Enoxolone
This study aims to assess the efficacy of a zinc oxide eugenol sealer containing Enoxolone, a non-steroidal anti inflammatory drug (NSAID) on the pain relief after endodontic treatment.
- Trial name
- NCT03874949
- Testing
- SEALITE Regular, SEALITE Ultra
- Where
- France
- Volunteers
- 95 people
- Sponsor
- ACTEON Group
Endodontically Treated Teeth
Endodontic Management of Primary Molars
The purpose of this study was to describe the clinical and radiological outcome of root canal treatment with OrthoMTA in primary second molars without successors in which traditional root canal treatment with gutta-percha could…
- Trial name
- NCT04691050
- Testing
- OrthoMTA (BioMTA)
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Endodontically Treated Teeth
Outcome of Root Canal Treatments Obturated With Calcium Silicate Based Sealers
The clinical use of a flowable premixed calcium-silicate bioceramic sealer used in association with warm carrier-based/single-cone technique will be compared with epoxy resin-based sealer with carrier-based technique.
- Trial name
- NCT05376033
- Testing
- root canal filling with Ceraseal sealer
- Where
- Italy
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Postoperative Pain
Postoperative Pain After Pulpectomy of Primary Molars
Testing postopertive pain after pulpectomy of primary molars with endoflas using modified Wong-Baker scale of pain.
- Trial name
- NCT06424353
- Testing
- Endoflas pulpectomy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Minia University