Clinical trials: Root Canal Disinfection
Apical Periodontitis, Postoperative Pain
Effect of Diode Laser on Post-operative Pain After Endodontic Treatment in Teeth With Apical Periodontitis
Aim: This study aims to assess the effect of root canal disinfection with a 980 µm diode laser following chemomechanical root canal preparation on the severity of pain after root canal treatment (RCT).
- Trial name
- NCT04486196
- Testing
- Medency Primo Diode Laser Device (Medency, Vicenza, Italy), 2.5% NaOCl, %17 EDTA, Distilled water, 30-gauge, side-opening needle (Canal Clean, Biodent, South Korea),
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Biruni University
Root Canal Infection, Pain
Postoperative Pain After Root Canal Disinfection Via Diode Laser
The prevention and control of post-treatment pain is of great importance for the comfort of the patient as well as for the clinician's prestige.
- Trial name
- NCT03584880
- Testing
- Diode laser disinfection, Pseudo diode laser disinfection
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Root Canal Infection, Periapical; Infection
Bacteria Elimination in Retreatment Cases Using Different Disinfection Techniques
Nonsurgical root canal retreatment may become essential when the initial endodontic treatment fails because of the persistent intracanal or extracanal infections.It has been stated that the one of the main cause of posttreatment…
- Trial name
- NCT03750162
- Testing
- VDW Ultra, AMD picasso, ProtaperNext X3 gutta-percha
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Endodontic Treatment
Disinfection Effect of Gaseous Ozone
The current study aimed to investigate the effect of gaseous ozone in disinfection the root canals of primary teeth. Thirty-six primary molars of 36 completely healthy patients (aged 5-10) were included in the study.The included…
- Trial name
- NCT06470126
- Testing
- 2.5% NaOCl group: The interventions performed in the study are root- canal therapies and disinfection procedure of these therapies., 0.9% sterile saline solution combined with 80 seconds: The OzonyTronX® interventions performed in the study are root- canal therapies and disinfection procedure of these therapies., 2.5% NaOCl with 80 seconds OzonyTronX®:The interventions performed in the study are root- canal therapies and disinfection procedure of these therapies.
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ankara University
Radiographic Healing of Periapical Lesions Following Ultrasonic Activation of Heated Sodium Hypochlorite Without Instrumentation of Root Canals
Minimally Invasive Root Canal Treatment With Active Disinfection on Single Rooted Teeth With Periapical Lesions
A novel form of root canal treatment RCT, referred as minimally invasive endodontics MIE, has emerged recently to adopt a unique approach that emphasize reducing tooth structural changes post-treatment (32).
- Trial name
- NCT06467643
- Testing
- non-instrumented root canal treatment with passive ultrasonic activation of heated sodium hypochlorite, conventional root canal treatment with passive ultrasonic activation of heated sodium hypochlorite
- Where
- Lebanon
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
This Study Will be Performed to Evaluate the Efficiency of 810 nm Diode Laser Disinfection on Periapical Healing in Root Canal Retreatment Cases
The Efficiency of 810 nm Diode Laser on Periapical Healing After Root Canal Retreatment
The main cause of endodontic disorders is microbial infection. From the infected root canal, microorganisms can penetrate into the deeper layers of root dentine and propagate a periapical tissue through the apical foramen and…
- Trial name
- Retreatment (NCT07194837)
- Testing
- diode laser, Calcium Hydroxide (Ca(OH)2)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Postoperative Pain
Effect of 980nm Diode Laser on Postoperative Pain and Root Canal Disinfection in Endodontic Retreatment Cases
A randomized clinical trial that evaluates the effect of using 980nm diode laser intracanal irradiation on postoperative pain and root canal disinfection in endodontic retreatment cases with chronic periapical lesions
- Trial name
- NCT03711357
- Testing
- 980 nm diode laser
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periapical Periodontitis
Comparison of Root Canal Desinfection Protocols
Evaluate and compare the disinfecting efficacy of two supplementary antimicrobial protocols in teeth with apical periodontitis
- Trial name
- NCT07439614
- Testing
- Desinfection device, Analytical microbiological methods
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Endodontic Disease
Photodynamic Therapy in Endodontic Treatment
This randomized clinical trial evaluated the effectiveness of supplemental photodynamic therapy (PDT) in optimizing the removal of bacteria and endotoxins from primarily infected root canals after one-visit and two-visit…
- Trial name
- NCT02824601
- Testing
- Laser, Calcium hydroxide
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Root Canal Disinfection
Estimate the Effect of aPDT on Root Canal Disinfection
The aim of this study is to compare the clinical effect of traditional root canal disinfection and aPDT on root canal disinfection. And provide the reference for clinical application and experience.
- Trial name
- NCT02929927
- Testing
- Rubber dam isolation, aPDT, 1% iodine tincture
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Endodontically Treated Teeth
Root Canal Disinfection: a Comparison Between Techniques
Caries disease is still the leading cause of severe tooth decay. Since this can lead to tooth loss, it is important that appropriate treatment is advised to help prevent damage and maintain tooth health.
- Trial name
- NCT03490526
- Testing
- Root canal disinfection with XP-endo Finisher, Root canal disinfection with passive ultrasonic irrigation
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Pulp and Periapical Tissue Disease, Pulp Necroses
The Efficacy of Laser in Root Canal Disinfection
The aim of this study is to assess in vivo the efficacy of Er,Cr:YSGG/diode laser and Diode/EDTA on bacterial count in root canal treatment in an evidence-based clinical trial.
- Conditions
- Pulp and Periapical Tissue Disease, Pulp Necroses, Pulp; Granuloma
- Trial name
- NCT05964686
- Testing
- Conventional group (NaOCl/EDTA), Dual laser group (Er,Cr:YSGG/Diode):, Combined group (EDTA/Diode):
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Root Canal Infection
Comparison of Effectiveness of Disinfectants
This is a comparative experimental study to compare the efficacy of chemical disinfection agents , sodium hypochlorite and chlorhexidine gluconate in decontaminating gutta percha cones
- Trial name
- NCT06811779
- Testing
- Sodium Hypochlorite, Chlorhexidine
- Where
- Pakistan
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Intracanal Medication
Effectiveness of Glycyrrhizin as Intracanal Medication in Root Canal Disinfection and Inflammatory Cytokines
The objective of this study is to investigate "clinically" the effectiveness of Glycyrrhizin based intracanal medication compared to the commonly used intracanal medicaments (calcium hydroxide Ca(OH)2 and Ledermix) on the levels…
- Trial name
- NCT06453304
- Testing
- Calcium Hydroxide, Leddermix, Glycirrhizin
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Endodontic Disease, Root Canal Infection
Erbium, Chromium: Yttrium, Scandium, Gallium, Garnet (Er,Cr:YSGG) Laser in Root Canal Disinfection
The purpose of this study is to develop a protocol for biofilms disinfection with a FDA cleared, clinically approved and commercially available Er,Cr:YSGG laser treatments.
- Trial name
- NCT05959629
- Testing
- Waterlase Express™, BIOLASE®, Sodium Hypochlorite
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Apical Periodontitis, Root Canal Infection
Clinical Investigation of Chemomechanical Parameters for an Efficient Disinfection of the Root Canal
The aim of the study is first, to evaluate the clinical antibacterial efficacy of two different NaOCl concentrations (2,5% and 5%) under a predefined irrigant flow rate in teeth with pulp necrosis and apical periodontitis by…
- Trial name
- ENDOA (NCT06949176)
- Testing
- Root canal tratment using mecchanical and chemical preparation., Sodium Hypochlorite., Hydrogen peroxide.
- Where
- Greece
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Root Canal Treatment, Post Operative Pain
A First in Human Study to Compare Feasibility of Inertial Cavitation Irrigation to SNI in Root Canal Treatment.
The study design is a single-center 2-arm randomized controlled clinical trial. 10 subjects (teeth) requiring a root canal treatment will be enrolled in 2 groups (5 in each group).
- Trial name
- NCT05374434
- Testing
- Conventional irrigation, Inertial cavitation
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Lumendo AG