Clinical trials: Root Canal
Rectal Cancer, Radiotherapy, Anal Pain
Mepilex Lite Dressings for the Treatment of Acute Radiation Dermatitis of Anal Canal Skin
Background: According to GLOBOCAN 2022 statistics, colorectal cancer has become the third most common cancer disease worldwide, and also the second leading cause of death.
- Conditions
- Rectal Cancer, Radiotherapy, Anal Pain, Acute Radiation Dermatitis, Anal Canal
- Trial name
- NCT06837831
- Testing
- Control group, Experimental group
- Where
- China
- Volunteers
- 274 people
- Sponsor
- Qianfoshan Hospital
Acute Pulpitis, Post Endodontic Pain
Comparison of Post-Operative Endodontic Pain Using Sodium Hypochlorite, Hydrogen Peroxide, and Normal Saline as Root Canal Irrigants
Pain is the main reason patients visit a dentist for root canal treatment. Sometimes, patients experience pain between visits, which can make the treatment uncomfortable and stressful.
- Trial name
- EPI-RCT (NCT07486245)
- Testing
- Sodium Hypochlorite 2.5%, Hydrogen Peroxide, Normal Saline (0.9% NaCl)
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- CMH Multan Institute of Medical Sciences
Gonarthrosis, Total Knee Arthroplasty
Infiltration or Nerve Blocks in Addition to Adductor Canal Block
The aim of this study is to evaluate the analgesic efficacy of this quadruple sensory block compared with the currently recommended procedure (adductor canal block + infiltration).
- Trial name
- INCA (NCT06920186)
- Testing
- Analgesia
- Where
- 2 sites in France
- Volunteers
- 100 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Lumbar Spondylolisthesis Involving L4-L5
Survivorship of Decompression Alone Vs Decomp With Fusion in DLS and LCS
There has been a long-standing controversy on the operative treatment of Degenerative Lumbar Spondylolisthesis (DLS) with Lumbar Canal Stenosis (LCS), especially whether the addition of fusion to decompression is necessary.
- Trial name
- NCT05386381
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Tooth Discoloration Following Root Canal Treatment, Tooth Discoloration
Clinical Evaluation of Discoloration Induced by Root Canal Treatment in Vital and Devital Teeth
This prospective observational study aims to evaluate and compare tooth discoloration following root canal treatment in vital and devital teeth.
- Trial name
- NCT07781969
- Testing
- Root Canal Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Marmara University
Root Canal Obturation
Root Canal Treatment With TotalFill® Bioceramic Sealer and AH Plus® Sealer
The study design is a double blinded randomized controlled trial and 170 subjects (teeth) , 85 in each of the 2 groups, will be enrolled from the patients at the NUH dental centre endodontic unit.
- Trial name
- NCT03732170
- Testing
- TotalFill® Bioceramic sealer, AH plus® sealer
- Where
- Singapore
- Volunteers
- 170 people
- Sponsor
- National University Hospital, Singapore
Pulpitis
Efficacy of Pediatric Rotary File System Versus Hand Instrumentation for Root Canal Preparation in Primary Teeth
The teeth were randomly allocated in two equal groups : Control group (A):- included 20 mandibular primary molars in which pulpectomy were performed by hand instrumentation system using K- File from size 15 to size 35.
- Trial name
- NCT06152354
- Testing
- rotary system, Manual files
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Suez Canal University
Root Canal Treatment
Comparison of AH Plus and WellRootST Root Canal Sealers in Terms of Postoperative Pain: One-Month Follow-up
The objective of this research was to identify which of the root canal sealers, AH Plus or WellRootST, yielded more effective outcomes regarding postoperative pain when applied to teeth diagnosed with apical periodontitis.
- Trial name
- NCT07246174
- Testing
- AH-Plus Epoxy Resin Sealer, bioceramic sealer
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medipol University
Knee Osteoarthritis
Liposomal Bupivacaine vs Adductor Canal Block in Total Knee Arthroplasty
This study is being done to evaluate the outcomes of patients undergoing total knee replacement with two different methods of local pain control:shots of liposomal bupivacaine, a long acting anesthetic, directly into the knee…
- Trial name
- NCT02863120
- Testing
- liposomal bupivacaine, bupivacaine HCl, Ropivacaine
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Texas Orthopaedics, Sports and Rehabilitation Associates
Anal Cancer Patients, Perianal Patients
MRI for Tumor During Chemoradiation for Anal Canal and Perianal Cancer
The purpose of this study is to establish a prospective database of anal canal and perianal cancer patients treated with IMRT and chemotherapy with curative intent at PMH for the purposes of investigating MRI-derived primary…
- Trial name
- NCT01053923
- Testing
- Magnetic Resonance Imaging (MRI)
- Sponsor
- University Health Network, Toronto
Irreversible Pulpitis, Apical Periodontitis
Ethanolic Extract of Sapindus Mukorrossi as Final Endodontic Irrigant.
The chief aim of root canal treatment is to reduce the microbial content and prevent further recontamination in the canal. Properly cleaned, shaped and obturated teeth will be having fewer chances of treatment failure.
- Conditions
- Irreversible Pulpitis, Apical Periodontitis, Root Canal Infection
- Trial name
- NCT05038059
- Testing
- ethanolic extract of sapindus mukorossi, ethylene diamine tetra acetic acid
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Asymptomatic Apical Periodontitis, Root Canal Retreatment
Non-Surgical Single Visit Endodontic Retreatment in Cases With Asymptomatic Apical Periodontitis Using Bioceramic Sealer
The goal of this clinical trial is to learn if using bioceramic sealers in non surgical single visit endodontic retreatment in patients with endodontic treatment failure and asymptomatic apical periodontitis will work in…
- Trial name
- NCT06973135
- Testing
- Bioceramic sealer root canal obturation, resin sealer root canal obturation
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Saly Nazeer
Hernia Lumbar, Lumbar Canal Stenosis
Erector Spinae Plane Block in Lumbar Release Surgery
The aim of this study is to observe or not a reduction in the consumption of morphine within 72 hours of the realization of an erector spinae plane block when preparing for a non-instrumented spine surgery.
- Conditions
- Hernia Lumbar, Lumbar Canal Stenosis, Spinal Cord Compression
- Trial name
- MERLIBERTION (NCT04925882)
- Testing
- Erector spinae plane block
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Clinique Saint Jean, France
Post-Operative Pain, Chronic
Intra-articular Analgesia Versus Adductor Canal Block for Arthroscopic Knee Surgery
This study is a randomized study that compares two commonly used post-operative pain reducing techniques by measuring the level of pain and use of pain medication after knee surgery.
- Trial name
- NCT05004506
- Testing
- Adductor Canal Block, Intra-articular Injection
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Loyola University
Postoperative Pain After Endodontic Treatment
Evaluation of the Effect of Salivary Melatonin Levels on Postoperative Pain and Sleep Quality Following Endodontic Treatments Performed at Different Days and Times
This clinical study aims to evaluate the effect of salivary melatonin levels on postoperative pain and sleep quality in patients undergoing root canal treatment at different times of the day.
- Trial name
- NCT07173699
- Testing
- root canal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ataturk University
Acute Postoperative Pain, Surgery
Continuous Versus Single Injection Adductor Canal Blocks for Outpatient Total Knee Arthroplasty
This is a single-center pilot study to determine if an adductor canal continuous nerve block is superior to single injection nerve block following total knee arthroplasty.
- Trial name
- NCT06784882
- Testing
- continuous peripheral nerve block with OnQ pump, single injection nerve block
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Diego
Apical Periodontitis, Root Canal Infection
Clinical Investigation of Chemomechanical Parameters for an Efficient Disinfection of the Root Canal
The aim of the study is first, to evaluate the clinical antibacterial efficacy of two different NaOCl concentrations (2,5% and 5%) under a predefined irrigant flow rate in teeth with pulp necrosis and apical periodontitis by…
- Trial name
- ENDOA (NCT06949176)
- Testing
- Root canal tratment using mecchanical and chemical preparation., Sodium Hypochlorite., Hydrogen peroxide.
- Where
- Greece
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Root Canal Infection, Periapical Periodontitis
Sealer-Based Obturation With AH Plus Bioceramic Sealer vs. Warm Vertical Compaction With AH Plus
The goal of this clinical trial is to assess the efficacy and outcome of sealer-based obturation (SBO) using a new calcium silicate sealer in comparison with warm vertical compaction (WVC) using a resin-based sealer, which is the…
- Conditions
- Root Canal Infection, Periapical Periodontitis, Periapical Diseases
- Trial name
- NCT05763420
- Testing
- AH Plus Bioceramic Sealer, AH Plus Sealer (resin-based)
- Where
- Kuwait
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Kuwait
Superior Canal Dehiscence Syndrome, Autophony
The Diagnostic Accuracy of Ankle Audiometry Performed With the B250 for Superior Canal Dehiscence Syndrome in Patients Affected by Pulsatile Tinnitus and/or Autophony Disorders
The goal of this clinical trial is to learn if the ankle audiometry test performed with the B250 bone conduction transducer can identify patients with superior canal dehiscence syndrome from those without among subjects…
- Conditions
- Superior Canal Dehiscence Syndrome, Autophony, Pulsatile Tinnitus
- Trial name
- AA by B250 (NCT07384091)
- Testing
- Ankle audiometry performed with the B250 transducer
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Region Stockholm
Anal Canal Cancer
Interstitial Brachytherapy Boost for Treatment of Anal Canal Cancers, Comparison of Two Dose Rates
Comparative retrospective study of two anal canal brachytherapy techniques aimed at boosting [low dose rate (LDR) and high dose rate (HDR)]
- Trial name
- BOOST-CA (NCT03465501)
- Testing
- Brachytherapy
- Where
- France
- Volunteers
- 89 people
- Sponsor
- Institut Paoli-Calmettes