Clinical trials: Root Canal
Root Canal Treatment
Clinical Performance of AH Plus Jet® Root Canal Sealers in Single-cone Protocols
A prospective, parallel-group, randomised, post-market clinical follow-up investigation evaluating the performance and safety of the modified formula of the AH Plus Jet® Endodontic Sealer (also referred to as ES) and the…
- Trial name
- NCT07642284
- Testing
- AH Plus Jet® Endodontic Sealer, AH Plus Jet® Root Canal Sealing Material
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Root Canal Obturation
Root Canal Obturation With a Ready-to-use Root Canal Sealer (PA1704) Versus BioRoot™ RCS: a Randomized Controlled Trial
The study design is a multicentric randomized controlled non-inferiority trial. 160 subjects (teeth) requiring a primary or a secondary root canal treatment will be enrolled in 2 groups (80 in each group).
- Trial name
- OPTIFILL (NCT04757753)
- Testing
- ready-to-use root canal sealer: PA1704, root canal sealer: BioRoot™ RCS
- Where
- 5 sites in Belgium, France
- Volunteers
- 160 people
- Sponsor
- Septodont
Root Canal Obturation
Endodontic Post-operative Pain Evaluation of Patients After Using Endomethasone N or Endomethasone SP (EndoPOP)
The study is a post-marketing performance and safety study, designed as a comparative, prospective, multicenter, simple-blind, randomized clinical trial.
- Trial name
- EndoPOP (NCT04885686)
- Testing
- Endomethasone N RCS, Endomethasone SP RCS
- Where
- 15 sites in France
- Volunteers
- 300 people
- Sponsor
- Septodont
Dental Root Canal Obturation
Tooth Retention After Root Canal Treatment With Endomethasone N
The aim of root canal treatment, or endodontic treatment, is to treat pulpal or periapical diseases and thus transform a pathological tooth into a healthy, asymptomatic and functional entity on the dental arch.
- Trial name
- ENDO2021-02 (NCT04945993)
- Testing
- Endomethasone N
- Where
- 5 sites in France
- Volunteers
- 179 people
- Sponsor
- Septodont
Root Canal Obturation
Measurement of the Clinical and Radiological Performance Impact of the Root Canal Treatment With BioRootTM RCS.
The aim of this retro-prospective Post-Market Clinical Follow-Up (PMCF) study is to collect long term clinical and safety data on root canal obturation after treatment, or retreatment, by BioRootTM RCS.
- Trial name
- BioRoot RCS (NCT05247138)
- Testing
- BioRootTM RCS
- Where
- 9 sites in France
- Volunteers
- 142 people
- Sponsor
- Septodont
Root Canal Treatment, Post Operative Pain
A First in Human Study to Compare Feasibility of Inertial Cavitation Irrigation to SNI in Root Canal Treatment.
The study design is a single-center 2-arm randomized controlled clinical trial. 10 subjects (teeth) requiring a root canal treatment will be enrolled in 2 groups (5 in each group).
- Trial name
- NCT05374434
- Testing
- Conventional irrigation, Inertial cavitation
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Lumendo AG
Root Canal Therapy
Sonendo GentleWave™ System for Treatment in Molar Teeth Requiring Root Canal Therapy
A prospective, literature controlled, clinical study evaluating healing rates for the Sonendo GentleWave System in the treatment of 1st and 2nd molars indicated for root canal therapy.
- Trial name
- SUPREME (NCT02285595)
- Testing
- Sonendo GentleWave™ System
- Where
- 3 sites in United States
- Volunteers
- 69 people
- Sponsor
- Sonendo, Inc.
Root Canal Obturation
Postoperative Pain After Root Canal Obturation With Sealer Containing Prednisolone.
The study design is a multicentric randomized controlled clinical trial. 238 subjects (teeth) requiring a primary or a secondary root canal treatment will be enrolled in 2 groups (119 in each group).
- Trial name
- NCT04935736
- Testing
- root canal sealer : CORTISOMOL SP, root canal sealer : SEALITE REGULAR
- Where
- 8 sites in France
- Volunteers
- 243 people
- Sponsor
- ACTEON Group
Root Canal Obturation
Pain After Root Canal Obturation With Sealer Containing or Not 1% Enoxolone
This study aims to assess the efficacy of a zinc oxide eugenol sealer containing Enoxolone, a non-steroidal anti inflammatory drug (NSAID) on the pain relief after endodontic treatment.
- Trial name
- NCT03874949
- Testing
- SEALITE Regular, SEALITE Ultra
- Where
- France
- Volunteers
- 95 people
- Sponsor
- ACTEON Group
Root Canal
A Study Evaluating the Sonendo GentleWave™ System
A post market, observational study evaluating the treatment of 1st and 2nd molars indicated for root canal therapy and treated with the Sonendo GentleWave System and obturated with CPoint and BC Sealer in at least one canal.
- Trial name
- To The Point (NCT02478723)
- Testing
- Sonendo GentleWave™ System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Sonendo, Inc.
Root Canal
The GentleWave Registry
The purpose of this registry is to gain a real world perspective for the use and outcomes associated with the Sonendo® GentleWave System usage.
- Trial name
- NCT02557152
- Testing
- GentleWave System Treatment
- Where
- 3 sites in United States
- Volunteers
- 500 people
- Sponsor
- Sonendo, Inc.
Root Canal Infection
Effect of Apical Negative Pressure Irrigation System at Cleaning Lateral Canals and Reduction of Periapical Lesions After Endodontic Therapy
The aim of the present study is to assess with PA x-rays and CBCT scans the volumetric changes in periapical radiolucencies in endodontically treated teeth 1 year after endodontic treatment and evaluate how well the lateral…
- Trial name
- NCT03384004
- Testing
- Irrigation Technique 1, Irrigation Technique 2
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KaVo Kerr