Clinical trials: Risk-Taking
Pathological Gambling
Memantine Treatment Study of Pathological Gambling
The goal of the proposed study is to evaluate the efficacy and safety of the drug memantine in individuals with pathological gambling (PG).
- Trial name
- NCT00585169
- Testing
- Memantine Hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- Yale University
Parkinson Disease
Motor Cortex Reward Signaling in Parkinson Disease
Background: The brain releases signals to mark rewards for certain behavior. Some medications for Parkinson disease (PD) can cause some patients to engage in compulsive behavior, possibly because the medications affect this…
- Trial name
- NCT00558766
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
HIV/AIDS, Sexual Behavior
Reducing HIV Risk in Urban Women: Soap Opera Videos on Video-Capable Cell Phones
Background: Love, Sex, and Choices (LSC) is a soap opera video series created to reduce HIV sex risk in women. Methods: LSC was compared to text messages in a randomized trial in 238 high-risk mostly Black young urban women.
- Conditions
- HIV/AIDS, Sexual Behavior, Woman's Role, Risk Behavior
- Trial name
- NCT03330522
- Testing
- Love, Sex, & Choices video series, Messages in text
- Where
- United States
- Volunteers
- 295 people
- Sponsor
- Northeastern University
Gambling
Brief Therapies for Problem Gambling Substance Abusers
This project evaluates the efficacy of brief interventions for individuals seeking treatment for substance use disorders who also have gambling problems.
- Trial name
- NCT00685048
- Testing
- 10 minutes of psycho-education, 10 minutes of brief advice, four 50-minute individual therapy sessions of MET & CBT
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- UConn Health
Travel Health, Mobile Health Technology (mHealth)
TOURIST 2: Tracking Of Urgent Risks In Swiss Travelers
New mobile Health (mHealth) technology creates an opportunity to approach travel medicine research in a different way, revolutionising our understanding of risks to travellers.
- Conditions
- Travel Health, Mobile Health Technology (mHealth), Elderly Travelers, Chronic Diseased Travelers
- Trial name
- TOURIST2 (NCT03262337)
- Testing
- none, this is an observational study
- Where
- 2 sites in Switzerland
- Volunteers
- 793 people
- Sponsor
- University of Zurich
Pathological Gambling
Effects of Internet-based Treatment of Pathological Gambling
A trial testing the outcome of an Internet-based treatment of pathological gambling with the hypothesis that there will be improvements both immediately and up to 36 months.
- Trial name
- NCT01381250
- Testing
- cognitive behavior therapy
- Where
- Sweden
- Volunteers
- 284 people
- Sponsor
- Umeå University
Unsafe Sex, Risk-Taking
Combined Prevention of Sexually Transmitted Infections (STIs) in Men Who Have Sex With Men and Using Oral Tenofovir Disoproxil Fumarate/ Emtricitabine (TDF/FTC) for HIV Pre-Exposure Prophylaxis (PrEP)
The study ANRS 174 Doxyvac is a clinical trial that will use Combined Prevention of Sexually Transmitted Infections (STIs) in Men Who Have Sex with Men and using oral TDF/FTC for HIV Pre-Exposure Prophylaxis (PrEP) and…
- Trial name
- DOXYVAC (NCT04597424)
- Testing
- Experimental: doxycycline, Bexsero® vaccine
- Where
- 9 sites in France
- Volunteers
- 556 people, healthy volunteers welcome
- Sponsor
- ANRS, Emerging Infectious Diseases
Gambling
Cognitive Motivational Behavior Therapy for Gamblers
This study will evaluate the effectiveness of cognitive motivational behavior therapy (CMBT) in treating pathological gamblers.
- Trial name
- NCT00069420
- Testing
- Cognitive Motivational Behavior Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University at Albany
Gambling, Gambling Disorder
Accelerated rTMS in Gambling Disorder: a Multicentric, Randomized, Sham-controlled Trial
Background: Gambling disorder (GD), is a behavioral addiction based on keeping play despite medical, economic and social consequences.
- Conditions
- Gambling, Gambling Disorder, Gambling, Pathological, Gambling Problem
- Trial name
- arTMSinGD (NCT05016479)
- Testing
- Accelerated repetitive Transcranial Magnetic Stimulation
- Volunteers
- 60 people
- Sponsor
- ITAB - Institute for Advanced Biomedical Technologies
Gambling, Mental Health
Cognitive-Behavioral Treatment of Gambling
This study will determine the effectiveness of cognitive behavior therapy (CBT) and contingency management (CM) in reducing gambling behaviors and other related problems in pathological gambling.
- Trial name
- CBT/CM (NCT00118391)
- Testing
- Cognitive behavior therapy, Contingency management
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- UConn Health
Chronic Subdural Hematoma, Anticoagulant-induced Bleeding
Management of Anticoagulants and Antithrombotics in Patients With CSDH
Primary objective of the study will be to compare, up to 6 months after surgery, number of relapses (post operative re-bleeding) or intracerebral hemorrhage (others than subdural hematomas) and thromboembolic or cardiovascular…
- Conditions
- Chronic Subdural Hematoma, Anticoagulant-induced Bleeding, Thromboembolic Stroke, Cardiovascular Stroke
- Trial name
- THERCA (NCT05079295)
- Testing
- CSDH evacuation
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- University Hospital of Ferrara
Pathological Gambling, Obsessive Compulsive Disorder
Functional Magnetic Resonance Imaging (fMRI) Studies in Pathological Gambling (PG) and Obsessive-Compulsive Disorder (OCD)
This study will explore the brain processes associated with inhibition and reward processing in pathological gamblers and people with obsessive compulsive disorder compared to healthy controls.
- Trial name
- NCT00211822
- Testing
- fMRI
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Gambling
Comparative Study of the Link Between the Practice of Gambling and Money and Materialism Among Problem Gamblers and Non-problem Gamblers
The purpose of this study is to to explore the link between materialism and addiction to gambling and money
- Trial name
- GAMMA (NCT02841566)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Risk Behavior, Alcohol Use Disorder
TRAC-ER Intervention to Reduce Risky Alcohol Use and HIV Risk
Ecological momentary interventions (EMI), which use phones to deliver messages to reduce alcohol use and related risk behaviors during or prior to drinking events, can help to address triggers in real-time.
- Conditions
- Risk Behavior, Alcohol Use Disorder, HIV Infections
- Trial name
- TRAC-ER (NCT05576350)
- Testing
- Smartphone Based Alcohol Monitoring (SAM), Tracking and Reducing Alcohol Consumption (TRAC), TRAC-ER
- Where
- 2 sites in United States
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- University of Kentucky
Gambling Disorder
COMpulsive Gambling: Efficacy of DEEP Transcranial Magnetic Stimulation With H7 COIL
This study aims to investigate whether a treatment called high-frequency repetitive transcranial magnetic stimulation (rTMS) can help reduce the symptoms of gambling disorder and whether it is safe and well tolerated.
- Trial name
- COMET-7 (NCT07828782)
- Testing
- active r-TMS
- Volunteers
- 60 people
- Sponsor
- Sveti Ivan Psychiatric Hospital
Pathological Gambler
Effect of rTMS in Pathological Gamblers
The gambling problem is characterized by a loss of control and an excessive focus on the gambling practice. Currently, the treatment of pathological gamblers is often complex and multidimensional, it notably includes…
- Trial name
- NCT02552524
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Drive, Adolescent Behavior
Translation Study of a Safe Teen Driving Intervention
Steering Teens Safe (STS) is an evidence-based and parent-focused intervention developed by the investigators, which aims to improve safe teen driving practices by enhancing parental communication skills.
- Conditions
- Drive, Adolescent Behavior, Risk Behavior
- Trial name
- NCT04317547
- Testing
- Steering Teens Safe (STS), Driving Feedback Technology.
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ginger Yang
Risk Behavior, Agitation
Detection of Risk Behaviors: Pilot Observational Study With Bedridden and Agitated Patients.
There is a risk of falls and injuries in bedridden hospitalized patients, increased in agitated or confused patients. In neurosurgery departments, brain damaged patients can present a loss of consciousness of risky behaviors and…
- Conditions
- Risk Behavior, Agitation, Hospitalization, Bedridden Patients
- Trial name
- DECORIPAA (NCT05522647)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Clermont-Ferrand
Mild Traumatic Brain Injury, Suicidal Ideation
Frontal iTBS for Impulsivity and Suicidal Ideation in Veterans With Mild Traumatic Brain Injury
The investigators hope to develop a treatment for suicidal ideation (SI), impulsivity and functional impairments (such as difficulties in social and work settings) that occur after a mild traumatic brain injury (mTBI).
- Conditions
- Mild Traumatic Brain Injury, Suicidal Ideation, Impulsivity
- Trial name
- NCT05647044
- Testing
- intermittent theta burst stimulation
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- VA Office of Research and Development
HIV Infections, Sexually Transmitted Infections
Evaluation of the Healthy Love Workshop, an HIV Prevention Intervention for African American Women
The purpose of this program evaluation is to determine whether the Health Love Workshop, a group-level HIV behavioral intervention, reduces HIV-related sex risk behaviors and increases HIV protective behaviors of African American…
- Trial name
- NCT00362375
- Testing
- Healthy Love Workshop, HIV/AIDS 101 Workshop
- Where
- United States
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention