Clinical trials: Risk-Taking
Gambling Disorder
Theta Burst Stimulation for Gambling Disorder
The goal of this clinical trial is to investigate the efficacy of theta burst stimulation in individuals with gambling disorder.
- Trial name
- NCT05872750
- Testing
- theta burst stimulation
- Where
- Taiwan
- Volunteers
- 75 people
- Sponsor
- Taipei City Hospital
Gambling Disorder, Substance Use Disorders
Integrative Couple Treatment for Gambling/Substance Use Disorder
The aim of the study is to compare couple-based treatment to individual treatment (treatment as usual) for addiction (gambling or substance use disorder).
- Trial name
- NCT05833503
- Testing
- Integrative Couple Treatment for Addiction (ICT-A), Treatment individual as usually offered
- Where
- 7 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Université du Québec à Trois-Rivières
Prostate Cancer
Study of Coronary Heart Disease (CHD) & Heart Failure (HF) Risk in Prostate Cancer Patients, Taking Casodex or Not
A retrospective cohort study performed in the GPRD,UK. All patients with incident prostate cancer identified between 1 Jan 1999 and 31 Dec 2005 and a frequency-matched cohort of the general population will be followed- up for two…
- Trial name
- NCT00688532
- Volunteers
- 5,103 people
- Sponsor
- AstraZeneca
HIV, Depression
Group Psychotherapy for People With HIV
This study will examine the effectiveness of supportive-expressive group therapy plus education compared with an educational intervention in improving the quality of life and promoting health-enhancing behavior of men and women…
- Conditions
- HIV, Depression, Risk-taking, Pain
- Trial name
- NCT00186550
- Testing
- Supportive Expressive Group Psychotherapy, Education
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- Stanford University
Risk Behavior
Comprehensive Elementary School Risk Prevention
This project will evaluate the benefit of an enhanced social development program in grades 3-6 to decrease the onset of risky behaviors in pre-adolescents.
- Trial name
- NCT00099385
- Testing
- Social Development Instruction
- Where
- United States
- Volunteers
- 2,620 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cognitive Ability, General, Psychiatric and/or Mood Disorders
The Bucharest Early Intervention Project
The purpose of this study is to determine the long term effects of early intervention (placement into foster care) on physical, cognitive, social and brain development and psychiatric symptomatology in previously…
- Conditions
- Cognitive Ability, General, Psychiatric and/or Mood Disorders, Brain Function, Social Cognition
- Trial name
- BEIP (NCT00747396)
- Testing
- Foster Care Placement
- Where
- Romania
- Volunteers
- 136 people
- Sponsor
- Charles Alexander Nelson III
Pathological Gambling
Investigation of Naltrexone for Pathological Gambling
The investigators plan to investigate the safety, tolerability, and efficacy of the opioid antagonist naltrexone in Pathological Gambling.
- Trial name
- NCT01057862
- Testing
- Naltrexone
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Yale University
Pathological Gambling
Topiramate Trial for Pathological Gamblers
Objectives: Pathological gambling (PG) is a prevalent disorder with no approved pharmacological treatment. Previous reports suggest that topiramate could be useful in reducing impulsivity in PG, and craving in other addictions.
- Trial name
- NCT01843699
- Testing
- Topiramate flexible dosage, 4-session gambling cognitive restructuring
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- University of Sao Paulo
Acute Lymphoblastic Leukemia, Childhood Acute Lymphoblastic Leukemia
A Study of Different Programs to Help ALL Patients With Taking Maintenance Medicine at Home
This clinical trial tests different programs to help patients with acute lymphoblastic leukemia (ALL) remember to take their medications during maintenance therapy at home.
- Trial name
- NCT06639958
- Testing
- Biospecimen Collection, Compliance Monitoring, Health Promotion and Education
- Where
- 27 sites in United States
- Volunteers
- 64 people
- Sponsor
- Children's Oncology Group
Marijuana Use Disorder
Effects of Smoked Marijuana on Risk Taking and Decision Making Tasks
The purpose of this study is to investigate the effects of smoked marijuana on both risk taking and decision making tasks.
- Trial name
- NCT00373399
- Testing
- Inactive Marijuana (0% THC), Low THC marijuana (1.8 %THC), High THC marijuana (3.9% THC)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Gambling Disorder
Effects of Transcranial Temporal Interference Stimulation on Risky Decision-making and Impulse Control in Gambling Disorder
The purpose of this research is to investigate the effect of transcranial temporal interference stimulation (tTIS) targeting the dorsal anterior cingulate cortex in patients with gambling disorder.
- Trial name
- NCT06467422
- Testing
- tTIS on dACC, theta frequency (5 Hz), tTIS on dACC, High frequency
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Mental Health Center
Insomnia, Impulsivity
Effects of CBT-I on Impulsivity and Risk Taking in Youths With Insomnia
Insomnia is prevalent in adolescents. Impulsive behaviours and excessive risk-taking have been linked to the manifestation of psychopathology in youths.
- Conditions
- Insomnia, Impulsivity, Risk-Taking
- Trial name
- NCT07399964
- Testing
- Cognitive Behavioural Therapy for Insomnia, Health-related Psychoeducation
- Where
- Hong Kong
- Volunteers
- 124 people
- Sponsor
- The University of Hong Kong
Gambling Disorder
Psilocybin AsSisted pSychotherapy for the treatmENt of Gambling disordER : a Pilot Study
The PASSENGER project aims to conduct a pilot feasibility study of the implementation of a randomized clinical trial on psilocybin-assisted psychotherapy for the treatment of gambling disorder.
- Trial name
- PASSENGER (NCT07391332)
- Testing
- Psychotherapy assisted by high-dose psilocybin (25mg or 40mg where appropriate), Psychotherapy assisted by low-dose psilocybin (1 mg)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Nantes University Hospital
Gambling
Prevention Messages for EGMs: Effects on Behaviours and Cognitions
The goals of this randomized controlled trial are to test the manifold effects of prevention pop-up messages on participants' behaviours, cognitions and affects.
- Trial name
- NCT06341504
- Testing
- Prevention pop-up messages, Mandatory time limit, Responsible gambling information
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Benjamin Galipeau
HIV Infections, Sexual Behavior
Examining the Effects of Theory-based Education on Individuals' Sexual Behavior.
The research was planned to examine the effect of the transtheoretic theory-based education given to individuals followed in AMATEM on their sexual risk-taking status, AIDS knowledge level and AIDS prevention self-efficacy.
- Trial name
- SEXUALRISK (NCT07145749)
- Testing
- Transtheoretical theory-based education, Pre-test-after-test-re-test
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Saglik Bilimleri Universitesi
Gambling
Evaluation of Effectiveness of the Unplugged Program on Gambling Among Adolescents (GAPUnplugged)
The main aim of this study is to assess the effectiveness of a new component on gambling prevention to be added to the evidence-based school based prevention curriculum "Unplugged".
- Trial name
- GAPUnplugged (NCT05630157)
- Testing
- Unplugged plus gambling component
- Volunteers
- 3,046 people, healthy volunteers welcome
- Sponsor
- Università degli Studi del Piemonte Orientale Amedeo Avogadro
Pathological Gambling
D1 and D2 Dopamine Receptors in Gambling and Amphetamine Reinforcement
To determine if: 1. pathological gambling is similar to psychostimulant addiction as reflected by parallel roles for D1 and D2 receptors in gambling and stimulant reinforcement. 2.
- Trial name
- HFDEX (NCT02203786)
- Testing
- Haloperidol, Fluphenazine, Dexedrine
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Pathological Gambling
A Pilot SMART Design for Pathological Gamblers
Pathological gambling is serious problem, with significant psychological, financial, and public health consequences. Nevertheless, controlled trials examining the efficacy of therapeutic interventions for pathological gamblers…
- Trial name
- SMART (NCT00685724)
- Testing
- Motivational Enhancement Therapy (MET), Cognitive-Behavioral Therapy (CBT)
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- UConn Health
Concurrent Alcohol Dependence and Pathological Gambling
Naltrexone in the Treatment of Concurrent Alcohol Dependence and Pathological Gambling
This study assessed whether naltrexone, an opioid antagonist, might be effective in reducing excessive gambling behavior in people who also drink heavily.
- Trial name
- NCT00326807
- Testing
- Naltrexone
- Where
- 2 sites in Canada, Finland
- Volunteers
- 50 people
- Sponsor
- Centre for Addiction and Mental Health
Gambling, Pathologic
Computer-based Self-Help Program for People With Gambling Problems
The study examines the effectiveness of a computer-based self-help-program for individuals with problematic or pathological gambling behavior.The main objective of the study is to investigate the extent to which the online…
- Trial name
- NCT03372226
- Testing
- Online self-help program
- Where
- Germany
- Volunteers
- 155 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf