Clinical trials: Risk Score
Cardiovascular (CV) Risk
Neqpiaput Iinruugut (Our Food Is Medicine): A Tribally Driven Food Sovereignty Intervention to Reduce Heart Disease Risk in Alaska Native Adults
This study Neqpiaput Iinruugut ("Our Food is Medicine"), will test if a tribally designed Indigenous food sovereignty intervention can lower the risk of coronary heart disease in Alaska Native adults ages 18 to 65 years old.
- Trial name
- Food is Med (NCT07897838)
- Testing
- Neqpiaput linruugut (Our Food is Medicine)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Alaska Fairbanks
Device-detected Atrial Fibrillation, Subclinical Atrial Fibrillation
Blood Clotting Markers and Heart Ultrasound in People With Device-Detected Atrial Fibrillation
The purpose of this observational study is to investigate whether blood tests related to blood clotting are associated with established clinical stroke risk scores, the total amount of device-detected atrial fibrillation recorded…
- Conditions
- Device-detected Atrial Fibrillation, Subclinical Atrial Fibrillation, Atrial High Rate Episodes
- Trial name
- DDAF-HEV (NCT07713615)
- Where
- Denmark
- Volunteers
- 222 people
- Sponsor
- Andreas Sjøholm-Christensen
Coronary Artery Disease (CAD), Computed Tomography Angiography
AI-assisted CT for Risk Stratification in Coronary Artery Disease (ACTION)
The goal of this observational study is to learn if AI-assisted cardiac CT imaging can improve cardiovascular risk stratification and prediction of future coronary events in an adult population undergoing clinically indicated…
- Conditions
- Coronary Artery Disease (CAD), Computed Tomography Angiography, Biomarkers, AI (Artificial Intelligence)
- Trial name
- ACTION (NCT07577609)
- Where
- Ireland
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Galway
Cardiogenic Shock
Prognostic Value of the Rockwood Clinical Frailty Score in Cardiogenic Shock
Cardiogenic shock (CS) is characterized by tissue hypoperfusion resulting from cardiac dysfunction, without hypovolemia, where the ventricular pump is unable to generate adequate blood flow to meet the metabolic needs of the…
- Trial name
- FrailShock (NCT06692855)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
Mitral Regurgitation
Abrogation of Mitral Regurgitation Using the MitraClip System in High-Risk Patients Unsuitable for Surgery
The primary objective in this randomized trial is to evaluate the safety and efficacy of a MitraClip treatment in symptomatic patients with severe mitral regurgitation in comparison to the previous default medical treatment - in…
- Trial name
- ISAR-CLIP (NCT01431222)
- Testing
- percutaneous treatment by implanting a Mitra Clip device
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Colorectal Cancer
Impact of DietarY and LIfestyle Risk Factors on Colorectal Cancer Screening
The main purpose of our project is to construct a lifestyle score based on a short questionnaire easy to complete and to validate it among participants in mass screening for colorectal cancer in Maine and Loire department over…
- Trial name
- IDYLIC (NCT02804802)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 49,000 people
- Sponsor
- University Hospital, Angers
Carotid Intima- Media Thickness
A Study to Derive Normative Distribution of CIMT and to Determine Its Correlation With Cardiovascular Risk Factors
This non-interventional, prospective, multi-centric, cross-sectional study is aimed to obtain the distribution of measurements of CIMT in Indian subjects and will involve approx. 30 investigative sites from all over the country.
- Trial name
- Score-India (NCT01551875)
- Where
- 24 sites in India
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Cardiovascular Risk
Association Between Framingham Risk Score, hsCRP and Vascular Inflammation: Analysis With 18F-Fluorodeoxyglucose Positron Emission Tomography
Framingham risk score is well known screening tool that detect cardiovascular (CV) risk. But it is not suitable for CV risk in mild risk group.
- Trial name
- NCT01139827
- Where
- South Korea
- Volunteers
- 178 people
- Sponsor
- Korea University Guro Hospital
Aortic Valve Stenosis
Randomized Trial of TAVI vs. SAVR in Patients With Severe Aortic Valve Stenosis at Low to Intermediate Risk of Mortality
Randomized controlled, multi-center trial randomizing patients with symptomatic severe aortic stenosis at low to intermediate operative risk of mortality in a 1:1 fashion to transcatheter aortic valve implantation (TAVI) or…
- Trial name
- DEDICATE (NCT03112980)
- Testing
- Transcatheter aortic valve implantation, Surgical aortic valve replacement
- Where
- 43 sites in Germany
- Volunteers
- 1,414 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Myocardial Infarction, Heart Failure
Personalised Risk scOre For Implantation of Defibrillators in Patients With Reduced LVEF≤35% and a Low Risk for Sudden Cardiac Death
The objective of the study is to demonstrate that in post-MI patients with symptomatic heart failure who receive optimal medical therapy for this condition, and with reduced LVEF ≤ 35% but low risk for SCD according to a…
- Conditions
- Myocardial Infarction, Heart Failure, Sudden Cardiac Death
- Trial name
- PROFID-Reduced (NCT04540354)
- Testing
- Optimal Medical Therapy (OMT), Implantable cardioverter-defibrillator (ICD)
- Sponsor
- Helios Health Institute GmbH
Medical Patients in the Emergency Department
National Early Warning Score and D-dimer to Identify Medical Patients At Low Risk of 30-day Mortality
The aim is to determine if the National Early Warning Score combined with plasma D-dimer levels can be used in risk stratification of acutely ill medical patients presenting to a Danish Emergency Department.
- Trial name
- NCT03108807
- Testing
- D-dimer test
- Where
- Denmark
- Volunteers
- 1,700 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Primary Prevention
Genetical, Anthropometrical and Biochemical Factors Influencing High Risk Subclinical Atherosclerosis
Subclinical atherosclerosis is the atherosclerotic process identified before clinical symptoms and thus it can be a useful marker of future cardiovascular events. It can be evaluated by many methods.
- Trial name
- NCT02487615
- Where
- 2 sites in Brazil
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Instituto Dante Pazzanese de Cardiologia
Hepatitis C Virus Infection, Compensated Advanced Chronic Liver Disease
Non-Invasive Risk Stratification for Hepatocellular Carcinoma in HCV-Related Compensated Advanced Chronic Liver Disease Following Sustained Virological Response: Validation of the aMAP Score
This retrospective cohort study evaluated the performance of non-invasive risk scores for predicting de novo hepatocellular carcinoma in adults with hepatitis C virus-related compensated advanced chronic liver disease who…
- Conditions
- Hepatitis C Virus Infection, Compensated Advanced Chronic Liver Disease, Hepatocellular Carcinoma (HCC)
- Trial name
- HCV-aMAP (NCT07687758)
- Testing
- Non-invasive Risk Score Assessment
- Where
- Thailand
- Volunteers
- 571 people
- Sponsor
- Siriraj Hospital
Postoperative Delirium, Postoperative Cognitive Dysfunction
Cognitive Dysfunction and Delirium After TUR-M in Elderly Patients
Elderly patients undergoing transurethral resection are at increased risk of postoperative cognitive dysfunction (POCD) and delirium, which are associated with prolonged hospital stay, increased morbidity, and decreased quality…
- Conditions
- Postoperative Delirium, Postoperative Cognitive Dysfunction, Cognitive Dysfunction
- Trial name
- POCDTURMSTUD (NCT07719712)
- Testing
- Cognitive and Delirium Assessment (MoCA and CAM)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Muğla Sıtkı Koçman University
Metabolic Health
Viome Nutritional Programs to Improve Clinical Outcomes for Metabolic Conditions
US residents who have obesity and sign the informed consent form and are screened and enrolled for this study. Participants who are enrolled complete a survey upon enrollment and are randomized into one of three arms.
- Trial name
- NCT05564273
- Testing
- VIOME Precision Nutrition Program, VIOME-designed condition-based supplements
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Viome
Chest Pain, Acute Myocardial Infarction
Risk Score Alerts for Chest Pain Care
The evaluation of chest pain in the primary care office is a challenging problem, with many patients suffering from missed diagnoses of acute myocardial infarction and many other low risk patients receiving unnecessary…
- Trial name
- NCT00674375
- Testing
- Electronic risk alerts
- Where
- 2 sites in United States
- Volunteers
- 8,000 people
- Sponsor
- Harvard Vanguard Medical Associates
Non-ST Elevation Myocardial Infarction (nSTEMI)
Risk-score Based ICU Triage
The investigators have created a new risk score that predicts whether initially stable patients with myocardial infarctions (heart attacks) will require intensive care while they are in the hospital.
- Trial name
- NCT03390270
- Testing
- Admission with NSTEMI
- Where
- United States
- Volunteers
- 462 people
- Sponsor
- Duke University
Ischemic Attack, Transient
Short-Term Prognosis Evaluation of Transient Ischemic Attack Patients Using ABCD2 Score
The purpose of this study is to determine whether the ABCD2 score can be used in patients with transient ischemic attack, admitted to Beijing anzhen hospital, to evaluate the prognosis, risk factor of those patients.
- Trial name
- NCT00553241
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Capital Medical University
Acute Cholecystitis
Validation and Comparison of Scores for Prediction of RIsk for Post-operative Major Morbidity After Cholecystectomy in Acute Calculous Cholecystitis (SPRIMACC)
The SPRIMACC study is a prospective multicenter observational study with the primary endpoint to prospectively validate the Chole-Risk score in predicting a complicated postoperative course (post-operative major complications…
- Trial name
- SPRIMACC (NCT04995380)
- Testing
- Early Cholecystectomy
- Where
- 2 sites in Italy, Spain
- Volunteers
- 1,261 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Cardiovascular Diseases
HOPE-CVD-Virtual: A Virtual Trial to Evaluate the Primary Prevention of CVD
This 4-arm (1:1:1:1) single-blind randomized controlled trial. Arm 1 will communicate risk and encourage behavioral change that mirrors the standard pathway for health screening in Singapore.
- Trial name
- NCT05827861
- Testing
- HeartAge, HOPE-CVD Mobile App, Genetic Risk Score
- Where
- Singapore
- Volunteers
- 1,121 people, healthy volunteers welcome
- Sponsor
- National University of Singapore