Clinical trials: Risk Reduction
Adolescent Behavior, Adolescent Problem Behavior
Tennessee Youth Prepared for Success
The principal objective of Tennessee Youth Prepared for Success is to pilot, implement, and test innovative adolescent pregnancy prevention strategies using a randomized controlled trial (RCT) to effectively educate youth on both…
- Conditions
- Adolescent Behavior, Adolescent Problem Behavior, Risk Reduction
- Trial name
- TYPS (NCT06001892)
- Testing
- Tennessee Youth Prepared for Success
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Centerstone Research Institute
Pediatric Obesity, Obesity
OBDIPHY (OBesity DIgital-PHYsical Care Study)
This is a prospective randomized controlled multicentre non-inferiority trial. The aim of this study to evaluate digi-physical care compared to regular physical/in person care and investigate if digi-physical care can be an equal…
- Conditions
- Pediatric Obesity, Obesity, Adolescent Obesity, Lifestyle Risk Reduction
- Trial name
- OBDIPHY (NCT05247918)
- Testing
- Digital-physical care, Treatment as usual
- Where
- 5 sites in Sweden
- Volunteers
- 102 people
- Sponsor
- Göteborg University
Eating Attitudes, Lifestyle Risk Reduction
Eating, Sleep, Attitudes, and Stress Risk in Physical Therapy Students
The goal of this observational study is to assess how eating attitudes, sleep attitudes, and perceived stress contribute to early indicators of cardiovascular risk among undergraduate physical therapy students aged 18-30.
- Conditions
- Eating Attitudes, Lifestyle Risk Reduction, Perceived Stress
- Trial name
- EHSAR-S (NCT07303244)
- Testing
- complete validated questionnaires
- Where
- Egypt
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Cairo University
Diabetes Mellitus, Type 2, Cardiovascular Diseases
Heart of the Family: A Cardiovascular Disease and Type 2 Diabetes Risk Reduction Intervention in High-Risk Rural Families
Rural populations in the U.S. are disproportionately burdened by cardiovascular disease and type 2 diabetes. Lifestyle modification interventions are needed that support long-term engagement in risk-reducing health behaviors.
- Trial name
- NCT04891575
- Testing
- Active Control Intervention educational sessions, Family Dyad Intervention
- Where
- United States
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- Gia Mudd
Hypertension, African Americans
Giving a Low Carbohydrate Diet to Overcome Hypertension
This study will test the preliminary efficacy of adding a very low carbohydrate dietary intervention to the evidence-based DPP-GLB on blood pressure reductions for lower-income AA men and women in a community-based clinic.
- Conditions
- Hypertension, African Americans, Diet, Carbohydrate-Restricted, Risk Reduction Behavior
- Trial name
- GLOH (NCT04230928)
- Testing
- Very low carbohydrate diet, Standard DPP-GLB diet, Standard DPP-GLB program modules
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Pre-diabetes, Lifestyle Risk Reduction
Evidence-based Intervention for Diabetes Prevention
The goal of this behavioral intervention trial is to develop strategies to decrease the incidence of diabetes within the UAE. The investigators will investigate the effectiveness of a group-based telehealth intervention…
- Conditions
- Pre-diabetes, Lifestyle Risk Reduction, Diet Prevention of Metabolic Diseases
- Trial name
- EID (NCT07443995)
- Testing
- Adapted diabetes prevention program, App based support, Patient education materials
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- New York University
Childhood Asthma, Asthma Control
Pollution Intervention to Impact Kids Asthma Study
The goal of this clinical trial is to learn if adding Air Quality Index (AQI) information to asthma action plans works to improve asthma outcomes in children.
- Conditions
- Childhood Asthma, Asthma Control, Asthma Exacerbation, Air Pollution, Risk Reduction Behaviors
- Trial name
- PIKAS (NCT07261423)
- Testing
- EPA-AQI, Commerical-AQI, Education and plan
- Where
- United States
- Volunteers
- 351 people
- Sponsor
- University of Pittsburgh
Allergic Contact Dermatitis, Metal Allergy
Environmental Exposure to Heavy Metals, Nanoparticles, and Emergent Contaminants and Risk of Allergic Diseases
The goal of this clinical trial is to collect environmental, bio-humoral, and clinical data derived from patients with allergic contact dermatitis (ACD) and systemic metal allergic syndromes related to the exposure to heavy…
- Conditions
- Allergic Contact Dermatitis, Metal Allergy, Food Allergy, Nickel Sensitivity
- Trial name
- MATRIOSKA (NCT06529913)
- Testing
- Collection of environmental, biological, and clinical data
- Where
- 2 sites in Italy
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Children, Only, Risk Reduction
Reducing Pesticide Exposures in Child Care Centers
A randomized control study was conducted to reduce the exposure to pesticides in child care centers. A 7-month child care health consultant-led integrated pest management (IPM) intervention was conducted in 85 child care centers…
- Conditions
- Children, Only, Risk Reduction, Environmental Exposure
- Trial name
- HCES (NCT03319927)
- Testing
- Changes in pesticide exposure, IPM Practices, Educational Workshops
- Where
- United States
- Volunteers
- 987 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Risk Reduction
PrEP Point-of-Care Brief-Intervention for Adherence Among Young Men Who Have Sex With Men
Despite advances in HIV prevention, the HIV incidence among young men who have sex with men (YMSM) is increasing, threatening to derail achievement of the United States End the HIV Epidemic goals.
- Trial name
- PrEP2-BAY (NCT05353283)
- Testing
- Motivational Interviewing Counselling, Point-of-care Urine Tenofovir Measurement
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
LGBTQ, Racial Disparities
Family Acceptance Project Online (Pilot RCT)
Research shows that sexual and gender minority youth (SGMY) experience high rates of mental health problems and other challenges (e.g., social, academic).
- Conditions
- LGBTQ, Racial Disparities, Family Relationships, Minority Stress
- Trial name
- FAP-O (NCT06839859)
- Testing
- Family Acceptance Project - Online
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cardiovascular Risk, Cardiovascular Disease Prevention
Digital Prevention Program With Telephonic Coaching
This study evaluates a digital health prevention program combining digital tools and structured telephonic coaching to support adult participants in improving health-related behaviors and well-being.
- Conditions
- Cardiovascular Risk, Cardiovascular Disease Prevention, Health Behavior Change, Lifestyle (Sedentary Behavior and Physical Activity)
- Trial name
- NCT07393646
- Testing
- Digital Health Platform, Telephonic Coaching
- Where
- France
- Volunteers
- 2,688 people, healthy volunteers welcome
- Sponsor
- Vivoptim Solutions
Mild Cognitive Impairment (MCI), Subjective Cognitive Decline (SCD)
LETHE-AT: a Personalized Multidomain Lifestyle Intervention for Individuals at Increased Risk of Memory Impairment.
The goal of this clinical trial is to learn whether a hybrid multidomain lifestyle program can prevent cognitive decline and reduce dementia risk in community-dwelling adults in mid- to late life who are at increased risk of…
- Trial name
- LETHE-AT (NCT07376135)
- Testing
- A tailored hybrid multidomain lifestyle intervention group, Self-guided multimodal lifestyle advice group
- Where
- 3 sites in Austria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Health Behavior, Noncommunicable Diseases
The LvL UP Trial: Assessing the Effectiveness of a mHealth Intervention
Non-communicable diseases (NCDs), such as cardiovascular disease, diabetes, or cancer, and common mental disorders (CMDs), such as depression or anxiety, represent the primary causes of death and disability worldwide, causing…
- Conditions
- Health Behavior, Noncommunicable Diseases, Mental Health Issue, Lifestyle Risk Reduction
- Trial name
- NCT06592443
- Testing
- LvL UP, LvL UP + MI, Comparison
- Where
- 2 sites in Singapore
- Volunteers
- 1,061 people, healthy volunteers welcome
- Sponsor
- Singapore ETH Centre
Memory Loss (Excluding Dementia), Healthy Lifestyle
Brain Health Program for Older Adults With Subjective Cognitive Decline
The investigators will compare two brain health programs in older adults with subjective cognitive decline and lifestyle risk factors for dementia.
- Conditions
- Memory Loss (Excluding Dementia), Healthy Lifestyle, Risk Reduction Behavior
- Trial name
- NCT05934136
- Testing
- My Healthy Brain 1, My Healthy Brain 2
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
PreDiabetes, Hyperglycemia
Effectiveness and Cost-Effectiveness of Fully-Automated Digital vs. Human Coach-Based Diabetes Prevention Programs
The purpose of this research study is to compare the effectiveness of a fully automated digital diabetes prevention program to standard of care human coach-based diabetes prevention programs for promoting clinically meaningful…
- Conditions
- PreDiabetes, Hyperglycemia, Glucose, High Blood, Overweight
- Trial name
- NCT05056376
- Testing
- Digital Diabetes Prevention Program (dDPP), Human Coach-based Diabetes Prevention Program (hDPP)
- Where
- 2 sites in United States
- Volunteers
- 368 people
- Sponsor
- Johns Hopkins University
Lifestyle Risk Reduction, Health Behavior
Food Literacy Intervention - is a "Train the Trainer" Approach Feasible and Effective?
Food literacy (FL) is the capability to make healthy food choices in different contexts, settings and situations. Although eating habits are shaped by different circumstances and skills, most nutrition programs focus on nutrition…
- Conditions
- Lifestyle Risk Reduction, Health Behavior, Food Habits
- Trial name
- NCT06258733
- Testing
- Lay-led FL workshops, Expert-led workshops
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Lifestyle Risk Reduction, Health Behavior
Development and Implementation of Food Literacy Workshops in the Community
Nutritional factors are responsible for 10% of the global health burden. In Israel, 31% of Jewish women and 52% of Arab women are obese.
- Conditions
- Lifestyle Risk Reduction, Health Behavior, Food Habits
- Trial name
- NCT03872752
- Testing
- FL lay leader training and workshop implementation
- Where
- Israel
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Worksite Health Promotion, Lifestyle Risk Reduction
Worksite Wellness Within Long-term Care Facilities
The goal of this proposed study is to test the feasibility and preliminary efficacy of worksite wellness program designed to reduce worker stress (job and personal) and improve cardiovascular disease among long-term care workers.
- Conditions
- Worksite Health Promotion, Lifestyle Risk Reduction, Cardiovascular Diseases, Occupational Stress
- Trial name
- NCT04166643
- Testing
- WHHIP PLUS, Education only control
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Community Dwelling, Elderly Adults
Effectiveness of Active Brain Construction Program in Community-Dwelling Older Adults
The urgency of health promotion and dementia prevention is paramount. In 2019, the World Health Organization announced the "Risk reduction of cognitive decline and dementia," which reviewed evidence-based prevention aspects and…
- Conditions
- Community Dwelling, Elderly Adults, Lifestyle Risk Reduction
- Trial name
- NCT07282626
- Testing
- ABC program with coaching, Active comparator (ABC Program)
- Where
- Taiwan
- Volunteers
- 75 people
- Sponsor
- National Taiwan University Hospital