Clinical trials: Risk Reduction
HIV, Sexually Transmitted Diseases
Reducing HIV Risk Among Adolescents: Evaluating Project HEART
This study evaluates an educational web-based intervention designed to increase adolescent girls' motivation and skills to engage in safer sexual behavior (Project HEART: Health Education and Relationship Training).
- Trial name
- NCT02579135
- Testing
- Safer Sex, Growth Mindsets
- Where
- United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- North Carolina State University
Sedentary Behavior
Exercise From Afar: Progressing At Risk Individuals to Independent Exercise
The purpose of this study is to investigate the efficacy of a technology-driven independent exercise program on health outcomes associated with dementia risk among underactive rural adults.
- Trial name
- NCT06667817
- Testing
- Exercise
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Emporia State University
Non-communicable Diseases (NCD)
Enabling Environments for Non-communicable Disease Risk Reduction in Ethiopia
The ENABLE study focuses on pregnant women attending routine antenatal care (ANC) in urban primary health care facilities in four Ethiopian cities.
- Trial name
- ENABLE (NCT07442318)
- Testing
- Structured lifestyle counseling integrated into ANC, Standard routine ANC
- Where
- 4 sites in Ethiopia
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Smoking Cessation
The Effectiveness of Using E-Cigarettes for Smoking Cessation and Decreasing Risk of Diseases Among Heavy Smokers
The goal of this clinical trial is to evaluate effectiveness of using e-cigarettes as harm reduction strategy for smoking cessation and decreasing risk of diseases in heavy smokers.
- Trial name
- NCT05639790
- Testing
- Electronic cigarettes + Health Counselling, Health Counselling
- Volunteers
- healthy volunteers welcome
- Sponsor
- Shenzhen Smoore Technology Limited
Cardiovascular Diseases, Metabolic Syndrome
Feasibility of Reducing Cardiovascular Disease Risk Factors in Hispanics Through a Family-Based Community Intervention
The purpose of this study is to evaluate the feasibility of a 6-month family-based community intervention to mitigate cardiovascular disease risk factors in Hispanic families in northern Colorado as measured through biometric…
- Trial name
- NCT05322876
- Testing
- Healthy Hearts Family Program
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Poudre Valley Health System
Smoking
Reduced Exposure Study Using THS 2.2 Menthol With 5 Days in a Confinement Setting and 85 Days in an Ambulatory Setting
The main goal of the study is to evaluate if the ad libitum use of the THS 2.2 Menthol (mTHS 2.2) for 5 days in confinement and after 85 days of product use in an ambulatory setting, by Japanese adult healthy smokers results in a…
- Trial name
- NCT01970995
- Testing
- THS 2.2 Menthol (mTHS 2.2), Smoking Abstinence (SA), Menthol Conventional Cigarette (mCC)
- Where
- Japan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Chronic Kidney Disease
Sleep Disturbances as a Non-Traditional Risk Factor in Chronic Kidney Disease- University of Illinois
This study will help determine the relationship between impaired sleep and chronic kidney disease, specifically to determine if sleep disturbances are a risk factor for worsening kidney function.
- Trial name
- CRIC (NCT00817492)
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Type 2 Diabetes Mellitus
The Effects of Reducing Prolonged Sitting Bouts in Individuals at High Risk of or With Type 2 Diabetes
Over 3 million in the United Kingdom are now diagnosed with type 2 diabetes, with current estimates suggesting this will rise to over 5 million by 2025.
- Trial name
- UP FOR 5 (NCT03482596)
- Testing
- Reducing/breaking prolonged sitting
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Obesity-Related Malignant Neoplasm
Weight Loss Intervention for the Reduction of Cancer Risk and Health Disparities in Rural Ohio
This study determines the feasibility of a telephone-based weight lost intervention in reducing cancer risk and health disparities in rural Ohio.
- Trial name
- HERO (NCT05040152)
- Testing
- Dietary Counseling and Surveillance, Exercise Intervention, Informational Intervention
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Methamphetamine Abuse, HIV/AIDS
FASTLANE II: Reducing Sex, Drug, and Mental Health Risk
The study uses a repeated measures, single group pretest-posttest design methodology to examine the feasibility, acceptability, and preliminary effectiveness of the FASTLANE II intervention aimed at decreasing risky sex behaviors…
- Conditions
- Methamphetamine Abuse, HIV/AIDS, Depression, Sex, Unsafe
- Trial name
- FLII (NCT04109014)
- Testing
- FASTLANE II
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Obesity
Reduction in Cardiovascular Risk Factors and Visceral Adipose Tissue in Men: Separate Effects of Diet- and Exercise-Induced Weight Loss
The purpose of the trial was to examine the independent effects of equivalent diet- or exercise-induced weight loss on obesity and related cardiovascular health risk factors.
- Trial name
- NCT00664547
- Testing
- Diet Weight Loss, Exercise Weight Loss, Exercise Without Weight Loss
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen's University
Transfemoral Amputees
Evaluation of an Acceleration-Based Prosthetic Knee Locking Mechanism for Reducing the Risk of Falling in Transfemoral Amputees
The investigators hypothesize that a new automatic prosthetic knee locking mechanism will improve gait characteristics during an induced controlled trip and reduce fear of falling.
- Trial name
- NCT01982721
- Testing
- Locking mechanism for prosthetic knee
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Hypertension, Vascular Disease
Real-World Validation of A Minimally Disruptive Ambulatory Blood Pressure Monitoring (ABPM) Huawei Smartwatch in Malaysia
Background: Ambulatory Blood Pressure Monitoring (ABPM) is the gold standard for diagnosing high blood pressure (hypertension) because it tracks blood pressure continuously across day and night.
- Conditions
- Hypertension, Vascular Disease, Cardiovascular (CV) Risk, Cardiovascular Disease
- Trial name
- Huawei-SunU02 (NCT07913607)
- Where
- Malaysia
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sunway University
Distracted Driving, Driving Impaired
Reducing Cell Phone Use While Driving Among High Risk UBI Auto Policy Holders
Insurance User Based Insurance (UBI) users will be invited to participate in a randomized control trial where they will be randomized into 1 of 4 arms: (Arm 1) standard UBI, (Arm 2) Standard UBI + Free phone mounts (Arm 3)…
- Trial name
- NCT04587609
- Testing
- Free Phone Mounts, Commitment Contract, Personalized Habit Tips
- Where
- United States
- Volunteers
- 1,668 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Stroke
Stroke COunseling for Risk REduction
The purpose of this study is to test the efficacy of the Stroke Counseling for Risk Reduction (SCORRE) intervention in increasing accuracy of perceived stroke risk and promoting lifestyle behavior change to reduce stroke risk in…
- Trial name
- SCORRE (NCT03076125)
- Testing
- SCORRE, Attention-Control Activity
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Reduction of Cardiovascular Risk Factors
PrevA Study - Evaluation of an App-based Nutritional Concept
The PrevA study is designed to evaluate our developed nutritional concept to implement a heart healthy diet. The nutritional concept based on nutrient-optimized daily menu plans for each study day.
- Trial name
- PrevA (NCT04717076)
- Testing
- App-based nutritional concept and fitness tracking, Nutritional concept with individual nutritional counselling, Nutritional concept without individual nutritional counselling
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Jena
Cardiovascular Risk Factor
Reducing Cardiovascular Risk of African Americans
Diseases such as hypertension and stroke affect mid-life and older African Americans at higher rates than Whites, negatively affecting health status of this group.
- Trial name
- NCT03339050
- Testing
- Health for Hearts United
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Florida State University
Stress Fracture, Injury
Vitamin D Supplementation in the Armed Forces
The study will comprise of an original investigation that will take the form of a prospective intervention (two matched groups) study.
- Trial name
- D_SAF (NCT03963128)
- Testing
- Supplementation Vitamin D3
- Where
- United Kingdom
- Volunteers
- 4,450 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Diet Modification, Substance Use Disorders
The Impact of a Parenting Intervention on Latino Youth Health Behaviors
The purpose of this study is to test if a parenting program can be used to prevent substance use among Latino youth and at the same time promote healthy eating.
- Conditions
- Diet Modification, Substance Use Disorders, Diabetes Mellitus Risk, Cardiovascular Risk Factor
- Trial name
- FPNG+ (NCT03517111)
- Testing
- Nutrition/substance use prevention, Substance use prevention only, Academic success program
- Where
- United States
- Volunteers
- 844 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Type 2 Diabetes
Community-integrated Nutrition Education to Prevent Type 2 Diabetes in Peel
The goal of this clinical trial is to assess the effectiveness of an intervention that delivers nutrition education based on the Portfolio Diet on type-2 diabetes (T2D) risk factors among adults who are without chronic…
- Trial name
- NCT07058558
- Testing
- Nutrition Education and Community Gardening
- Where
- 2 sites in Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Toronto