Clinical trials: Rhinitis
Chronic Rhinitis
Efficacy of Azelastine and Mometasone Irrigation in Comparison to Nasal Sprays in Patients With Chronic Rhinitis
The goal of this clinical trial is to determine the best combination of drugs and drug delivery routes to treat surgically naive chronic rhinitis patients.
- Trial name
- NCT05626621
- Testing
- Azelastine (137 mcg/spray) Nasal Spray and Mometasone (50 mcg/spray) Nasal Spray, Mometasone Nasal Irrigation (1 mg capsule), Mometasone (1 mg) and Azelastine (1 mg) Nasal Irrigation
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Seasonal Allergic Rhinitis
Efficacy and Safety of LP-003 Injection in Patients With Moderate to Severe Seasonal Allergic Rhinitis
This is a multicenter, randomized, double-blind, placebo-controlled phase III clinical study to evaluate the efficacy and safety of LP-003 injection in patients with moderate to severe seasonal allergic rhinitis inadequately…
- Trial name
- NCT07291284
- Testing
- LP-003
- Where
- China
- Volunteers
- 546 people
- Sponsor
- Longbio Pharma
Rhinitis, Allergic
Efficacy and Safety of Levocetirizine Versus Loratadine for the Treatment of Perennial Allergic Rhinitis
Efficacy and Safety of Levocetirizine Versus Loratadine for the Treatment of Perennial Allergic Rhinitis.
- Conditions
- Rhinitis, Allergic, Perennial
- Trial name
- NCT00524836
- Testing
- levocetirizine dihydrochloride
- Volunteers
- 71 people
- Sponsor
- UCB Pharma
Rhinitis
Phenylephrine Pediatric Pharmacokinetic Study
To characterize the pharmacokinetics of phenylephrine in two pediatric populations: children, ages 2 to <12 years, and adolescents, ages 12 to <18 years.
- Trial name
- NCT00762567
- Testing
- phenylephrine HCl
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
Rhinosinusitis
Topical Antibiotic Use In Chronic Rhinosinusitis A Double-Blinded, Randomized, Placebo Controlled Study
Chronic rhinosinusitis is a pervasive and costly disease. Recent estimates describe over 20 million Americans suffering from this diagnosis at a cost of over $4.3 billion per year.
- Trial name
- NCT00669799
- Testing
- gentamyacin
- Where
- United States
- Sponsor
- University of South Florida
Allergic Rhinitis
Study of CM310 in Subjects With Allergic Rhinitis
This is a multicenter, randomized, double-blind, placebo-controlled phase III clinical study aimed at evaluating the efficacy and safety of CM310 in patients with seasonal allergic rhinitis, and observing the quality of life, PK…
- Trial name
- PHECDA (NCT05908032)
- Testing
- CM310
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Keymed Biosciences Co.Ltd
Rhinitis, Urticaria
Evaluation of Desloratadine When Used in Patients With Either Allergic Rhinitis or Chronic Idiopathic Urticaria
Eligible patients will be prescribed Desloratadine 1 tablet of 5 mg once daily. Patients will be asked to follow-up for a final visit after 14 days (Day 15) where the safety, tolerability and clinical efficacy will be measured.
- Trial name
- Aerius (NCT00724698)
- Testing
- Desloratadine
- Volunteers
- 3,011 people
- Sponsor
- Organon and Co
Allergic Rhinitis
Evaluation of the Efficacy and Safety of an Intensified Strategy of Intratonsillar Immunotherapy (ITIT) for Allergic Rhinitis: A Multicenter, Randomized, Double-blind, Controlled Trial
This is a multicenter, randomized, double-blind, controlled trial to evaluate the efficacy and safety of an enhanced strategy of allergen-specific immunotherapy (ITIT) in the treatment of allergic rhinitis.
- Trial name
- NCT07269509
- Testing
- Basic Intratonsillar Immunotherapy (ITIT), Strengthen Intratonsillar Immunotherapy (ITIT)
- Where
- China
- Volunteers
- 276 people
- Sponsor
- Renmin Hospital of Wuhan University
Nasal Congestion Due to Allergic Rhinitis
Study to Find Out Whether Participants With a History of Stuffy Nose Due to Allergic Reactions in the Nose Would Intend to Buy Drug Phenylephrine Hydrochloride Extended Release Tablets After Receiving it Once in This Study
The researchers in this study want to find out whether participants with a history of stuffy nose due to allergic reactions in the nose would intend to buy drug Phenylephrine Hydrochloride (Phenylephrine HCl) extended release…
- Trial name
- NCT04534452
- Testing
- Phenylephrine HCl (Sinus Comfort, BAY112476)
- Where
- United States
- Volunteers
- 347 people
- Sponsor
- Bayer
Rhinitis, Allergic
The Efficacy and Safety of Cettum for Perennial Allergic Rhinitis
The purpose of this study is verify the efficacy and safety of Cettum (Electrical moxibustion) for patients with perennial allergic rhinitis.
- Trial name
- NCT03342105
- Testing
- Cettum, Acupuncture
- Volunteers
- 40 people
- Sponsor
- Eun Jung Kim
Rhinitis, Allergic, Perennial
Study in Adult and Adolescent Subjects With PAR (Perennial Allergic Rhinitis)
The purpose of the study is to assess the efficacy and safety of an investigational nasal aerosol compared with placebo nasal aerosol in the treatment of perennial allergic rhinitis.
- Trial name
- NCT01134705
- Testing
- Beclomethasone dipropionate hydrofluoroalkane HFA Nasal Aerosol
- Where
- 35 sites in United States
- Volunteers
- 474 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Allergic Rhinitis
A Study of the Effects of Single Dose Corticosteroids on Response to Allergens
This study will investigate whether changes in inflammatory mediators produced by the nose after exposure to an allergen can be used to evaluate the anti-inflammatory effects of novel drugs for the treatment of allergic asthma.
- Trial name
- NCT00828061
- Testing
- prednisone
- Volunteers
- 19 people
- Sponsor
- Merck Sharp & Dohme LLC
Mild Asthma and Allergic Rhinitis
To Investigate the Safety, Pharmacodynamics and Effect on Allergic Reactivity of the Toll-like Receptor 7 (TLR7) Agonist GSK2245035 in Subjects With Respiratory Allergies
The purpose of this study is to examine the safety and effects on the immune system of treatment with GSK2245035 in subjects who suffer from nasal symptoms caused by an allergy to pollen or perennial allergen, with or without…
- Trial name
- NCT01788813
- Testing
- GSK2245035
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- GlaxoSmithKline
Rhino Sinusitis
Herbal Tea Extract for Management of Rhinosinusitis
The objective of this phase I controlled clinical trial is to determine the safety and efficacy of Berry leaves \& Mango leaves mixture in symptomatic treatments on disease-related quality of life in adults with clinically…
- Trial name
- NCT07534280
- Testing
- mango leaves extract, local steroids, nasal saline
- Where
- 2 sites in Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Deraya University
Allergy, Respiratory Disease
Impact of AIT on Allergic Rhinitis and Asthma
The study will assess the effectiveness of AIT treatment in real clinical practice in Germany.
- Trial name
- NCT04125888
- Testing
- Allergy immunotherapy (AIT)
- Where
- Denmark
- Volunteers
- 92,048 people
- Sponsor
- ALK-Abelló A/S
Seasonal Allergic Rhinitis
Efficacy and Safety of Sublingual Tablets of Grass Pollen Allergen Extract
The objective of this study is to assess the effect of grass pollen extract SLIT tablets on the Rhinoconjunctivitis Total Symptom Score (RTSS) of the six rhinoconjunctivitis symptoms in response to grass pollen challenge after…
- Trial name
- NCT00619827
- Testing
- 300 IR grass pollen allergen extract tablet
- Where
- Austria
- Volunteers
- 89 people
- Sponsor
- Stallergenes Greer
Covid19
COVID-19 and Acute Invasive Fungal Rhinosinusitis
Data for acute invasive rhinosinusitis was obtained from the Otorhinolaryngology departments at our tertiary hospital at the period from January 2017 to December 2020.
- Trial name
- NCT04809480
- Testing
- Fungal rhinosinusitis
- Volunteers
- 56 people
- Sponsor
- Al-Azhar University
Asthma, Asthma in Children
Allergy, Asthma, and Atopic Eczema in Finland
The summary is available at --> https://www.finnatopy.fi/summary
- Conditions
- Asthma, Asthma in Children, Allergy, Rhinitis, Allergic
- Trial name
- FinnATOPY (NCT06330974)
- Testing
- No intervention, No Intervention: Observational Cohort
- Where
- Finland
- Volunteers
- 1,200,000 people
- Sponsor
- Tampere University
Rhinitis, Allergic, Seasonal
Untersuchung Zur Erfassung Und Kontrolle Der Lebensqualität Unter Einer Therapie Mit Pollinex Quattro Bei Heuschnupfen
Questionnaire to measure and control the quality of life of patients with hay fever who are treated or were treated with Pollinex quattro
- Trial name
- NCT03014661
- Testing
- Quality of life under or after therapy with Pollinex quattro
- Where
- Germany
- Volunteers
- 58 people
- Sponsor
- Universität des Saarlandes
Asthma
Charcot Leyden Crystals in Pathology
Charcot Leyden crystals (CLC) are sometime reported in pathological reports of airway or sinonasal samples but their clinical significance remain elusive.
- Trial name
- CLCpath (NCT03999242)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier