Clinical trials: Rhinitis, Allergic, Perennial
Perennial Allergic Rhinitis
Investigation of the Effects of a Multispecies Probiotic Formulation on Perennial Allergic Rhinitis
The goal of this clinical trial is to learn if a probiotic formulation consisting of multiple bacterial strains has a positive effect on the quality of life of participants with chronic perennial allergic rhinitis symptoms.
- Trial name
- AllerGo (NCT07157462)
- Testing
- Multi-species probiotic powder for oral solution. Dietary supplement containing six bacterial strains (Lactobacillus and Bifidobacterium species)
- Where
- France
- Volunteers
- 97 people
- Sponsor
- Winclove B.V.
Rhinitis, Allergic, Perennial
ATAREAL (Antihistamine Treatment for Allergic Rhinitis in Real Life)
Comparison of clinical efficacy and safety of levocetirizine in PER continuous versus on demand, measured by evolution of individual symptom scores during 6 months.
- Trial name
- NCT00160680
- Testing
- Levocetirizine
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- UCB S.A. - Pharma Sector
Rhinitis, Allergic, Perennial, Rhinitis, Allergic, Seasonal
Effect of a 10,000 EU Dose of Endotoxin in Allergic and Mildly Asthmatic Adults
The purposes of this pilot safety study are to identify a dose of inhaled Clinical Center Reference Endotoxin (CCRE) that is well tolerated by allergic subjects that induces measurable increases in neutrophil content of induced…
- Conditions
- Rhinitis, Allergic, Perennial, Rhinitis, Allergic, Seasonal, Asthma
- Trial name
- NCT00839189
- Testing
- Clinical Center Reference Endotoxin (CCRE)
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Allergy
Safety of ToleroMune House Dust Mite (HDM) to Treat House Dust Mite Allergy in HDM Allergic Subjects With Rhinoconjunctivitis
The prevalence of allergic sensitisation to House Dust Mite (HDM) varies from region to region and depends on the regional prevalence of HDM.
- Trial name
- NCT01008332
- Testing
- Toleromune HDM
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Circassia Limited
Perennial Allergic Rhinitis
Effects of Pine Cone Extract on Serum IgE Levels in Perennial Rhinitis
The medicinal properties of pinecones have been used for years to treat a variety of illnesses. In the mouse model, an extract of pine cones, poly-phenylpropanoid-polysaccharide complex (PPC), has been shown to reduce total serum…
- Trial name
- PCE (NCT04024033)
- Testing
- pine cone extract
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of South Florida
Perennial Allergic Rhinitis, Probiotics
the Efficacy and Safety of Probiotics eN-Lac® Capsules of Children With Perennial Allergic Rhinitis
The purpose of this study is to evaluate the efficacy and safety of probiotics eN-Lac® capsules (Lactobacillus paracasei GMNL-32) for the treatment of children with perennial allergic rhinitis(PAR).
- Conditions
- Perennial Allergic Rhinitis, Probiotics, Lactobacillus Paracasei GMNL-32 (eN-Lac®)
- Trial name
- PAR (NCT01116778)
- Testing
- eN-Lac®
- Where
- 4 sites in Taiwan
- Volunteers
- 236 people
- Sponsor
- GenMont Biotech Incorporation
Rhinitis Allergic
A Study Assessing the Safety and Effectiveness of FEX60/PE10 Fixed Combination Tablet in Patients With Allergic Rhinitis
Primary Objective: To assess the safety of twice-daily fexofenadine 60 mg/phenylephrine 10 mg (FEX60/PE10) combination tablet in patients with allergic rhinitis.
- Trial name
- NCT02401191
- Testing
- FEX60/PE10
- Where
- Japan
- Volunteers
- 105 people
- Sponsor
- Sanofi
Chronic Obstructive Pulmonary Disease (COPD), Asthma Patients
Evaluation of Nasal Biomarkers for Objective Assessment of Disease Severity in Respiratory Disorders
This research study is an observational, single site study quantifying expression of biomarkers of respiratory disease in nasal fluid using the ABEL microsampler device.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Asthma Patients, Asthma and Rhinitis, Asthmatic Patients
- Trial name
- ENBOARD (NCT06661252)
- Testing
- ABEL microsampler device
- Where
- Australia
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Diag-Nose Medical Pty Ltd
Rhinitis, Allergic, Perennial
Phase 4 Fluticasone Furoate Nasal Spray (VERAMYST) Long Term Pediatric Growth Study.
The primary objective of this study is to characterize, as accurately as possible, the estimation of the difference in pre-pubescent growth velocities between subjects treated continuously for one year with FFNS 110mcg QD, the…
- Trial name
- NCT00570492
- Testing
- Fluticasone furoate nasal spray
- Where
- 74 sites in United States, Argentina and 5 more
- Volunteers
- 474 people
- Sponsor
- GlaxoSmithKline
Perennial Allergic Rhinitis
Levocetirizine in the Treatment of Nasal Obstruction Due to Perennial Allergic Rhinitis
The purpose of this study is to show that in patients suffering from perennial allergic rhinitis levocetirizine 5 mg OD relieves nasal obstruction.
- Trial name
- NCT00439712
- Testing
- Levocetirizine
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Institut für Atemwegsforschung GmbH
Rhinitis, Allergic, Perennial
Seasonal Allergic Rhinitis In Pediatric Subjects
The purpose of this study is to determine if the investigational drug is effective and safe in children with seasonal allergic rhinitis.
- Trial name
- NCT00107757
- Testing
- GW685698X
- Where
- 65 sites in United States
- Volunteers
- 576 people
- Sponsor
- GlaxoSmithKline
Asthma, House Dust Mite Allergy
Dose Ranging Study of SLIT Tablets of House Dust Mite Allergen Extracts (HDM) in Adults With HDM-associated Allergic Asthma
The purpose of this study is to investigate the efficacy and safety of different doses of sublingual tablets of house dust mite allergen extracts as compared to placebo in adults with house dust mite-associated allergic asthma.
- Trial name
- NCT01930461
- Testing
- SLIT tablets of HDM allergen extracts, 3 different doses (A), SLIT tablets of HDM allergen extracts, 3 different doses (B), SLIT tablets of HDM allergen extracts, 3 different doses (C)
- Where
- 5 sites in France, Germany and 1 more
- Volunteers
- 386 people
- Sponsor
- Stallergenes Greer
Rhinitis Allergic, Persistent
Evaluation of Safety of Levocetirizine in Routine Clinical Practice-non- Interventional Study
To evaluate over a period of 6 months the safety and the treatment satisfaction of newly prescribed levocetirizine in patients of age ≥ 2 years with persistent allergic rhinitis.
- Trial name
- NCT00598780
- Where
- United States
- Volunteers
- 7,870 people
- Sponsor
- UCB Pharma
Asthma, Dermatitis, Atopic
Impact in Off-spring of Mothers After Perinatal Daily Intake of a Probiotic
A probiotic (Lactobacillus rhamnosus GG) supplement to pregnant women the last four weeks of pregnancy and three months after birth is expected to give a 40% reduction in risk of atopic sensitisation and allergic disease at two…
- Conditions
- Asthma, Dermatitis, Atopic, Rhinitis, Allergic, Perennial
- Trial name
- NCT00159523
- Testing
- Probiotic
- Where
- Norway
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Rhinitis, Allergic, Perennial, Hayfever
Randomised Controlled Clinical Trials of the Effect of Therapeutic Hookworm Infection in Allergic Rhinoconjunctivitis
There has been considerable debate over the last 30 years about the interaction between asthma and parasitic infection. It has been suggested that at least part of the reason for the increasing prevalence of asthma in the…
- Conditions
- Rhinitis, Allergic, Perennial, Hayfever, Allergy
- Trial name
- NCT00232518
- Testing
- Infection with hookworm larvae
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Nottingham
Perennial Allergic Rhinoconjunctivitis, House Dust Mite Allergy
A Study to Investigate an Immunomodulatory Therapy in Adult Patients With Perennial Allergic Rhinoconjunctivitis
The purpose of the study is to test the efficacy of the combination treatment AllQbG10 in patients with perennial allergic rhinoconjunctivitis due to house dust mite allergy in a double-blind placebo-controlled setting
- Trial name
- NCT00574223
- Testing
- CYT005-AllQbG10 (combination of house dust mite allergen extract with CYT003-QbG10)
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Cytos Biotechnology AG