Clinical trials: Rheumatoid Arthritis (RA)
Rheumatoid Arthritis (RA)
L-carnitine Supplementation in Rheumatoid Arthritis Patients
This study aims to evaluate the effect of l-carnitine as add- on therapy for improving the outcome in rheumatoid arthritis patients.
- Trial name
- NCT06753565
- Testing
- Carnitine, Disease-modifying anti-rheumatic drugs
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- German University in Cairo
Rheumatoid Arthritis
Imaging of Lymphatic Vessels in People With Rheumatoid Arthritis (RA)
Lymphatic transport was previously examined by these investigators using Near InfraRed Indocyanine Green fluorescence imaging (NIR-ICG) of the upper extremities.
- Trial name
- NCT05197530
- Testing
- Indocyanine green, MultiSpectral Imaging System
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Rochester
Rheumatic Diseases, Inflammatory Arthritis
Personalized Outreach for Equitable Treatment in Rheumatology
The primary goal of this study is to determine whether providing patient honoraria and/or outreach services can improve the attendance rate of appointments at an inner city rheumatology clinic in Vancouver, British Columbia.
- Conditions
- Rheumatic Diseases, Inflammatory Arthritis, Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA)
- Trial name
- POET-Rheum (NCT07022756)
- Testing
- Honoraria, Outreach
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Rheumatoid Arthritis (RA
A Study of Iguratimod in Combination With Tofacitinib in RA Patients
Rheumatoid arthritis (RA) is a common chronic inflammatory autoimmune disease characterized by synovitis, which can cause joint pain, deformity, and extra-articular symptoms, seriously affecting the quality of life and lifespan…
- Trial name
- NCT06945666
- Testing
- Combined therapy of Iguratimod and tofacitinib
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Jie Chang
Rotator Cuff-related Shoulder Pain, Shoulder Osteoarthritis
Could a Feedback Device Help Manage Work-related Shoulder Disorders?
Work-related shoulder pain is a common problem with significant socio-economic repercussions. The impact of these disorders on workers is considerable, particularly in terms of pain, disability and reduced quality of life.
- Conditions
- Rotator Cuff-related Shoulder Pain, Shoulder Osteoarthritis, Rheumatoid Arthritis (RA)
- Trial name
- NCT06693479
- Testing
- Shoulder watch load (SWL) feedback, Education
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Laval University
Rheumatoid Arthritis
A Study is to Assess Efficacy and Safety of Tacrolimus in Active Rheumatoid Arthritis Patients Who Showed Unsuccessful Response to Existing Disease Modifying Antirheumatic Drugs (DMARDs)
This study is to assess efficacy and safety of tacrolimus in active rheumatoid arthritis patients who showed unsuccessful response to existing DMARDs.
- Trial name
- TREASURE (NCT01511003)
- Testing
- Tacrolimus
- Where
- 4 sites in South Korea
- Volunteers
- 128 people
- Sponsor
- Astellas Pharma Inc
Rheumatoid Arthritis (RA)
Complementary Herbal Approach to Rheumatoid Management Study (CHARMS)
Rheumatoid Arthritis (RA) is a chronic disease characterised by symmetric, polyarticular pain and swelling, involving small joints of the hands and feet.
- Trial name
- CHARMS (NCT07627893)
- Testing
- Shu Bi Ning (modified Si Miao Xiao Bi), Methotrexate
- Where
- Singapore
- Volunteers
- 132 people
- Sponsor
- Singapore General Hospital
Rheumatoid Arthritis
Evaluation of Long-term Safety and Effectiveness of Fostamatinib in the Treatment of Rheumatoid Arthritis (RA)
The purpose of this study is to evaluate the long term safety and tolerability of fostamatinib in patients with rheumatoid arthritis (RA).
- Trial name
- OSKIRA-X (NCT01242514)
- Testing
- Fostamatinib
- Where
- 308 sites in United States, Argentina and 29 more
- Volunteers
- 1,917 people
- Sponsor
- AstraZeneca
Rheumatoid Arthritis
A 12 Week Study to Assess Changes in Joint Inflammation Using Ultrasonography in Patients With Rheumatoid Arthritis (RA)
To evaluate the changes in joint inflammation produced by Cimzia over 12 week Treatment period measured by Power/Color Doppler and Gray scale Ultrasound.
- Trial name
- SWIFT (NCT01292265)
- Testing
- Certolizumab Pegol
- Where
- 6 sites in United States
- Volunteers
- 3 people
- Sponsor
- UCB Pharma
Rheumatoid Arthritis
Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Disease Modifying Anti-rheumatic Drug (DMARD) But Not Responding.
The purpose of the study is to evaluate the effectiveness of two dosing regimens of fostamatinib compared to placebo, in patients with rheumatoid arthritis (RA) who are taking disease modifying anti-rheumatic drug (DMARD) but not…
- Trial name
- OSKIRA - 2 (NCT01197534)
- Testing
- fostamatinib
- Where
- 149 sites in United States, Canada and 14 more
- Volunteers
- 913 people
- Sponsor
- AstraZeneca
Recurrence (Disease Attribute)
Combination Therapy Prevents the Relapse of RA
This trial aims to compare the cost effective and effect of preventing recurrence by different treatment of TFP and HCQ combined SSZ for remittent RA.
- Trial name
- NCT02320630
- Testing
- Entanercept, HCQ, MTX
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Peking University First Hospital
Rheumatoid Arthritis
Evaluation of the Effectiveness and Safety of Two Dosing Regimens of Olokizumab (OKZ), Compared to Placebo, in Subjects With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate But Have Active Disease
The purpose of this study was to determine how effective and safe the study drug Olokizumab was in patients with Rheumatoid Arthritis (RA) who had been already receiving, but not fully responding to treatment with methotrexate…
- Trial name
- CREDO 1 (NCT02760368)
- Testing
- Olokizumab
- Where
- 40 sites in Belarus, Bulgaria and 1 more
- Volunteers
- 428 people
- Sponsor
- R-Pharm International, LLC
Rheumatoid Arthritis (RA) and Sjögren's Disease (SjD)
A Study to Assess Safety, Cellular Kinetics and Exploratory Efficacy of Rapcabtagene Autoleucel in Rheumatoid Arthritis and Sjogren's Disease
A study to assess safety, cellular kinetics and exploratory efficacy of rapcabtagene autoleucel in rheumatoid arthritis and Sjogren's disease
- Trial name
- NCT07048197
- Testing
- Rapcabtagene autoleucel
- Where
- 12 sites in France, Germany and 2 more
- Volunteers
- 27 people
- Sponsor
- Novartis Pharmaceuticals
Arthritis, Rheumatoid
The Clinical Efficacy of Immunomodulators in RA Patients
This study includes naive patients and csDMARDs-IR RA patients, treated with different regimens such as Iguratimod combination of different csDMARDs, or csDMARD with TNF inhibitors for 24 weeks.
- Trial name
- NCT05626348
- Testing
- Iguratimod, Methotrexate, Adalimumab Injection
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Qilu Hospital of Shandong University
Rheumatoid Arthritis, Pregnancy Related
Treatment of Pregnancy RA
It is important to control the disease of pregnant women with rheumatoid arthritis to ensure the fetal and maternal health. Frequent disease flare can increase the risk of adverse pregnancy outcomes, including abortion, premature…
- Trial name
- NCT04569890
- Testing
- Certolizumab Pegol 200 MG/ML [Cimzia], Hydroxychloroquine, Prednisone
- Where
- China
- Volunteers
- 100 people
- Sponsor
- RenJi Hospital
Rheumatoid Arthritis (RA)
Clinical Study Comparing Diosmin vs Rebamipide as Adjuvant Therapies vs Conventional Therapy in Patients With Rheumatoid Arthritis
This study will be a randomized controlled parallel study that will be conducted on 66 patients with active rheumatoid arthritis who will be diagnosed with RA according to American College of Rheumatology (ACR)/European League…
- Trial name
- NCT07745426
- Testing
- Diosmin, Rebamipide 100mg, Convential medical treatment
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Tanta University
Rheumatoid Arthritis
dnaJ Peptide for Relieving Rheumatoid Arthritis
A small protein called dnaJ peptide may help people with rheumatoid arthritis (RA) by preventing their immune system cells from attacking their own tissues.
- Trial name
- NCT00000435
- Testing
- dnaJ peptide
- Where
- 8 sites in United States
- Volunteers
- 160 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Rheumatoid Arthritis, Interstitial Lung Disease
Treatment Outcome and Prognostic Factors for Rheumatoid Arthritis (RA) Patients With Interstitial Lung Disease (ILD)
The objectives of this single center, prospective, non-interventional cohort is to understand patient characteristics, general treatment patterns, effectiveness/safety of conventional disease modifying antirheumatic drug (DMARD)…
- Trial name
- NCT03099525
- Testing
- ILD
- Where
- South Korea
- Volunteers
- 600 people
- Sponsor
- Hanyang University
Rheumatoid Arthritis
Observational Study of Tocilizumab in Participants With Rheumatoid Arthritis in Australia
This multi-center, observational study will evaluate the treatment patterns in clinical practice, efficacy and safety of tocilizumab in participants with rheumatoid arthritis (RA) who have had an inadequate response (or were…
- Trial name
- NCT01683604
- Testing
- Observational study
- Where
- 7 sites in Australia
- Volunteers
- 37 people
- Sponsor
- Hoffmann-La Roche
Anemia, Rheumatoid Arthritis
Randomized, Double-blind, Placebo-controlled Study to Assess Fatigue in Patients With ACD Due to RA Receiving PROCRIT
The purpose of this research study is to determine fatigue (tiredness) in subjects with chronic Rheumatoid Arthritis with chronic anemia.
- Trial name
- NCT00236678
- Testing
- Epoetin alfa
- Volunteers
- 29 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.