Clinical trials: Rheumatic Heart Disease
Toxoplasmosis, Rhd
Measuring the Prevalence of Toxoplasmosis and Its Socio-economic Consequences
The investigators propose a fast and inexpensive procedure to determine the prevalence of the Toxoplasmosis infection (Toxoplasma Gondii) in the general population, using response times in a cognitive task instead of costly…
- Trial name
- EconToxo (NCT05860998)
- Testing
- Presence of Toxoplasma gondii IgG Antibodies
- Volunteers
- 120 people
- Sponsor
- University of Zurich
Cardiac Disease, Pregnancy Related
Prevalence of Rheumatic Heart Disease Among Pregnant Women in Kenya
There is currently no routine screening for cardiac disease for pregnant women in areas of high prevalence. This study will aim to determine the point prevalence of cardiac disease in women presenting for antenatal care at Moi…
- Trial name
- NCT03411993
- Testing
- Focused cardiac echography
- Where
- Kenya
- Volunteers
- 612 people, healthy volunteers welcome
- Sponsor
- Moi University
Rheumatoid Arthritis, Atherosclerotic Ischemic Disease
Coronary Computed Tomography Angiography In Rheumatoid Arthritis Study
The Coronary Computed Tomography Angiography in Rheumatoid Arthritis study is part of the multinational, prospective, observational Autoimmunity and Atherosclerosis in Rheumatic Diseases cohort (https://atacc-rd.com) that…
- Conditions
- Rheumatoid Arthritis, Atherosclerotic Ischemic Disease, Pulmonary Disease, Depressive Disorder
- Trial name
- COTIRA (NCT07363980)
- Where
- 4 sites in Denmark
- Volunteers
- 4,000 people
- Sponsor
- Ellen Margrethe Hauge
Cardiac Diseases, Sickle Cell Disease
Domestication and Implementation of the PEN-Plus Clinical Model in the Zambian Health System
Cognizant of the prevalence of complicated non communicable diseases (NCD) and the attendant capacity problems faced by the health workers in primary care settings, we propose to adapt and pilot the Package of Essential…
- Conditions
- Cardiac Diseases, Sickle Cell Disease, Hypertension, Diabetes Mellitus
- Trial name
- PEN Plus (NCT07753681)
- Testing
- Supportive treatment
- Where
- Zambia
- Volunteers
- 2,084 people
- Sponsor
- Centre for Infectious Disease Research in Zambia
Diabetes Mellitus, Congestive Heart Failure
Relative Impacts on Preventative Primary Care--a Longitudinal Evaluation of COVID-19:Phase 1
The goal of this observational study is to describe the impacts of COVID-19 on primary care chronic condition management in Canada within various patient populations.
- Conditions
- Diabetes Mellitus, Congestive Heart Failure, Chronic Kidney Diseases, Chronic Obstructive Pulmonary Disease
- Trial name
- RIPPLE-C (NCT05813652)
- Testing
- Pre-pandemic time period (Jun 22, 2018 to March 12, 2020), Peri-pandemic time period (March 13, 2020 to December 3, 2021)
- Where
- Canada
- Volunteers
- 919,928 people
- Sponsor
- McMaster University
Osteo Arthritis, Osteoporosis
Determining the Feasibility of Implementing a Combined Cognitive and Exercise Training Program for Older Adults in a Community Setting.
The overarching aim of this project is to implement and evaluate a proven cognitive training regimen in combination with a community exercise program among older adults who attend wellness exercise programs at the YMCA.
- Conditions
- Osteo Arthritis, Osteoporosis, Joint Replacement, Fibromyalgia
- Trial name
- NCT04515758
- Testing
- Exercise and Cognitive Training, Exercise Training Only
- Where
- Canada
- Volunteers
- 43 people
- Sponsor
- University of Waterloo
Rheumatic Valvular Heart Disease, Obstructive Sleep Apnea
CPAP Treatment and Postoperative Outcomes in Patients With Rheumatic Valvular Heart Disease
The prevalence of OSA (Obstructive sleep apnea，OSA) is 2%-4% in general population and 16%-47% in surgical-heart failure patients.
- Trial name
- CPAP (NCT03398733)
- Testing
- continuous positive airway pressure
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Nanjing Medical University
Heart Failure, Cardiovascular Risk Factor
Cardiovascular Profiles in Rheumatoid Arthritis
Cardiovascular disease is the leading cause of death in RA patients. This increased risk may be apparent even before the clinical recognition of RA.
- Conditions
- Heart Failure, Cardiovascular Risk Factor, Rheumatoid Arthritis, Myocardium; Injury
- Trial name
- RA-HF (NCT03960515)
- Volunteers
- 400 people
- Sponsor
- Maria Betânia Almeida Dias Ferreira
Chronic Mental Illness, Chronic Physical Illness
Evaluation of the Texas Wellness Incentives and Navigation (WIN) Project
The Wellness Incentives and Navigation (WIN) project is designed to help improve health self-management and reduce the incidence and consequences of chronic disease among non-elderly adult Medicaid Supplemental Security Income…
- Trial name
- WIN (NCT02440906)
- Testing
- Patient-Directed Wellness Account, Health Navigator
- Where
- United States
- Volunteers
- 1,663 people
- Sponsor
- University of Florida
Carotid Artery Plaque, Ankylosing Spondylitis
Effects of Rosuvastatin on Carotid Artery Plaques in Patients With Inflammatory Joint Disease
Patients with rheumatoid Arthritis (RA) and Ankylosing Spondylitis (AS) are at greater risk of developing cardiovascular disease.
- Conditions
- Carotid Artery Plaque, Ankylosing Spondylitis, Rheumatoid Arthritis
- Trial name
- RORAAS (NCT01389388)
- Testing
- Rosuvastatin
- Where
- Norway
- Volunteers
- 114 people
- Sponsor
- Diakonhjemmet Hospital
Osteoarthritis
Balneotherapy and Echocardiographic Findings in Osteoarthritis
This prospective observational study aims to evaluate changes in heart function using echocardiography before and after a standardized balneotherapy program in adult and elderly patients with osteoarthritis.
- Trial name
- NCT06923969
- Testing
- balneotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Bursa City Hospital
Rheumatoid Arthritis, Cardiovascular Disease
Cardiovascular Outcomes in the VA's Rheumatoid Arthritis(VARA) Population
Rheumatoid arthritis (RA) is a symmetric, peripheral polyarthritis of uncertain etiology that can lead to joint deformity and destruction. However, the effects of RA are not confined simply to joint involvement.
- Conditions
- Rheumatoid Arthritis, Cardiovascular Disease, Coronary Disease
- Trial name
- NCT00431405
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- Dallas VA Medical Center
Atrial Fibrillation, Osteoarthritis of the Knee
Assays for and Reversal of New Anticoagulants
New anticoagulants are being introduced to replace warfarin. These drugs do not require monitoring and are safer. There is currently no recommended way to reverse these drugs rapidly in the event of undue bleeding or need for…
- Conditions
- Atrial Fibrillation, Osteoarthritis of the Knee, Osteoarthritis of the Hip
- Trial name
- NCT01795781
- Where
- Australia
- Volunteers
- 30 people
- Sponsor
- R.P.Herrmann
Mitral Valve Stenosis
Mitral Valve Area Assessment: Comparison With Transthoracic Echocardiography and Magnetic Resonance Imaging
To compare mitral valve area in rheumatic mitral valve stenosis with cardiac magnetic resonance imaging and conventional transthoracic echocardiography.
- Trial name
- NCT00654472
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Florence Nightingale Hospital, Istanbul
Hip Disease, Heart Failure
How Does Patients' Overall Assessment of Their Health Vary Across and Within Different Disease Groups?
EQ-5D is one of the most commonly employed patient-reported outcome (PRO) measures. It is included in many of the Swedish National Quality Registers (NQRs).
- Conditions
- Hip Disease, Heart Failure, Psoriasis, Fractures, Bone
- Trial name
- SWEQR (NCT04359628)
- Where
- Sweden
- Volunteers
- 700,000 people
- Sponsor
- Vastra Gotaland Region
Rheumatic Heart Disease, Valvular Disease
Role of Statins In Slowing Rheumatic Heart Disease (RHD) Progression
The goal of this study is to address specific implementation questions necessary and sufficient to ensure the feasibility of the larger randomized trial examining the efficacy of statin medications in slowing rheumatic heart…
- Trial name
- NCT04575857
- Testing
- Atorvastatin
- Where
- Nepal
- Volunteers
- 100 people
- Sponsor
- University of Washington
Rheumatoid Arthritis
Cardiac and Pulmonary Assessment in Egyptian Patients With Rheumatoid Arthritis
To determine cardiac and pulmonary involvement in RA patients To assess the correlation between cardiopulmonary findings in RA patients with disease activity. To compare between diaphragmatic ultrasonography and PFT i.e.
- Trial name
- NCT05938244
- Volunteers
- 34 people
- Sponsor
- Assiut University
Mitral Valve Stenosis
Late Clinical Outcomes of Percutaneous Mitral Commissurotomy in Patients With Mitral Stenosis
In this retrospective cohort study, out of 220 patients who had undergone successful PTMC between 2006 and 2018, the clinical course of 186 patients could be successfully followed.
- Trial name
- NCT04112108
- Testing
- PTMC
- Where
- Iran
- Volunteers
- 220 people
- Sponsor
- Shiraz University of Medical Sciences
Infections, Heart Failure
Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient Outcomes
Sub-optimal transfer of clinical information during inter-hospital transfer (IHT, the transfer of patients between acute care hospitals) is common and can lead to patient harm.
- Conditions
- Infections, Heart Failure, COPD Exacerbation, Asthma
- Trial name
- NCT05443321
- Testing
- Health Information Exchange (HIE) platform
- Where
- United States
- Volunteers
- 1,006 people
- Sponsor
- Brigham and Women's Hospital
Osteoarthrosis
Effect of Methylprednisolone on Orthostatic Intolerance and Heart Rate Variability in Hip-arthroplasty Patients
The study evaluates the pathophysiological effects of a single dose Methylprednisolone administered prior to total hip-arthroplasty (THA) surgery.
- Trial name
- NCT02445898
- Testing
- Methylprednisolone, Isotonic Sodium Chloride
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet