Clinical trials: Retinal Detachment Rhegmatogenous
Rhegmatogenous Retinal Detachment, Primary Vitrectomy
Primary Vitrectomy With Silicone Oil or SF6 for Rhegmatogenous Retinal Detachment
Rhegmatogenous retinal detachment (RRD) is the separation of the neurosensory retina from the retinal pigment epithelium caused by the presence of a break that leads to the passage of fluid from the vitreous cavity into the…
- Trial name
- NCT05377606
- Testing
- Pars plana vitrectomy with silicone oil, Pars plana vitrectomy with SF6
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Cairo University
Retinal Detachment
Randomized Controlled Trial of LUtein as a Novel Neuroprotective Adjunctive Therapy to Improve Visual Outcome of Rhegmatogenous Retinal Detachment (LUNAR Study)
Retinal detachment is a major cause of blindness, particularly among contemporary Asian populations due to the high prevalence of myopia. Without timely treatment, retinal detachment invariably results in blindness.
- Trial name
- NCT03932305
- Testing
- Lutein
- Volunteers
- 110 people
- Sponsor
- Singapore National Eye Centre
Rhegmatogenous Retinal Detachment
Efficacy of Oral Colchicine in Prevention of Proliferative Vitreoretinopathy in Rhegmatogenous Retinal Detachment
This clinical trial will test the efficacy and safety of oral colchicine in prevention of proliferative vitreoretinopathy (PVR) in cases of rhegmatogenous retinal detachment
- Trial name
- NCT00370201
- Testing
- colchicine
- Where
- Iran
- Sponsor
- Shahid Beheshti University of Medical Sciences
Retinal Detachment, Proliferative Vitreoretinopathy
Efficacy of 5-fluorouracil and Low Molecular Weight Heparin in High-risk Pediatric Retinal Detachment
EVALUATION OF 5-FLOUROURACIL AND LOW MOLECULAR WEIGHT HEPARIN INTRAOPERATIVE INFUSION IN PREVENTING PROLIFERATIVE VITREORETINOPATHY IN HIGH RISK PEDIATRIC RHEGMATOGENOUS RETINAL DETACHMENT
- Trial name
- NCT06166914
- Testing
- Intraoperative infusion of 5-FU (200 µg/ml) and LMWH (5 IU/ml)
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Alexandria University
Retinal Detachment
Evolution of Aqueous Flare in Rhegmatogenous Retinal Detachments Treated With Gas or Silicone Oil Tamponade.
To examine and to compare the evolution of aqueous flare from presentation until the third postoperative month in a series of consecutive patients who underwent primary vitrectomy for rhegmatogenous retinal detachment (RRD), in 4…
- Trial name
- FLADESIL (NCT05053698)
- Testing
- Aqueous flare measurement
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Central Hospital, Nancy, France
Retinal Detachment
Duration of Silicone Oil Tamponade on Foveal and Parafoveal Thickness in Rhegmatogenous Retinal Detachment
Our study observes and analyses the influence of the duration of tamponade with silicone oil on the foveal and parafoveal thickness.
- Trial name
- siliconeoil (NCT05817630)
- Testing
- Silicone oil Tamponade for Retinal Detachment
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Dar El Oyoun Hospital
Retinal Detachment Rhegmatogenous, Vitrectomy
Influence of Tamponade on Retinal Shift in Eyes Undergoing Vitrectomy for Rhegmatogenous Retinal Detachment: A Comparison of Gas Versus Silicone Oil in a Pakistani Population
Rhegmatogenous retinal detachment (RRD) is a vision-threatening condition with an estimated incidence of approximately 1 in 10,000 individuals annually.
- Conditions
- Retinal Detachment Rhegmatogenous, Vitrectomy, Retina Disorder
- Trial name
- TARS (NCT07495319)
- Testing
- Pars plana vitrectomy
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Wardah
Rhegmatogenous Retinal Detachment, Retinal Detachment
Anatomical and Functional Outcomes of Pneumatic Retinopexy for Retinal Detachment: A 2-Year Case Series
The goal of this observational study is to evaluate the 2-year anatomical and functional outcomes of pneumatic retinopexy in phakic adult patients with superior rhegmatogenous retinal detachment meeting adapted PIVOT eligibility…
- Trial name
- NCT07794163
- Testing
- Pneumatic Retinopexy
- Where
- Colombia
- Volunteers
- 33 people
- Sponsor
- Clinica Oftalmologica Paredes
Retinal Detachment, Full Thickness Macular Hole
Inflammasomes in Cell Death in FTMH, ERM, and RRD
Prospective study evaluating the role of inflammasomes in cell death in retinal detachment, full thickness macular hole, and epiretinal membrane.
- Conditions
- Retinal Detachment, Full Thickness Macular Hole, Epiretinal Membrane
- Trial name
- NCT03332758
- Testing
- Pars plana vitrectomy, External drainage
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Allen C. Ho, MD
Rhegmatogenous Macula-off Retinal Detachment
Safety and Efficacy of Brimonidine Tartrate Posterior Segment Drug Delivery System in Improving Visual Function
This study will evaluate the efficacy and safety of the Brimo PS DDS® Applicator System (200 μg and 400 μg brimonidine tartrate) on visual function in patients with previous rhegmatogenous macula-off retinal detachment.
- Trial name
- NCT00972374
- Testing
- 400 ug Brimonidine Implant, 200 ug Brimonidine Implant
- Where
- 6 sites in United States, India and 4 more
- Volunteers
- 44 people
- Sponsor
- Allergan
Rhegmatogenous Retinal Detachment, Surgery
Treating Rhegmatogenous Retinal Detachment by Foldable Capsular Buckle
To evaluate the efficacy and safety of treating rhegmatogenous retinal detachment (RRD) using foldable capsular buckle (FCB). It is a multi-center clinical ,randomized, controlled, and single-blind clinical study.
- Trial name
- NCT04571788
- Testing
- Foldable Capsular Buckle, Silicone scleral padding
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Aier School of Ophthalmology, Central South University
Rhegmatogenous Retinal Detachment - Macula Off
Acute Retinal Detachment Repair With the iSeelr™ Retinal Detachment Repair System
This study is a first-in-human clinical trial testing a new treatment for rhegmatogenous retinal detachments. The new treatment called retinal thermofusion uses a special laser device called iSeelr™ during surgery.
- Trial name
- NCT06468397
- Testing
- iSeelr™
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- Photofuse Pty Ltd
Rhegmatogenous Retinal Detachment
hAM for Inferior RRD
The objective of the study is to evaluate the efficacy of using hAM patches over the retina to seal inferior retinal breaks. The researchers will evaluate whether hAM patch-assisted vitrectomy improves surgical success rate of…
- Trial name
- NCT07081945
- Testing
- hAM
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Retinal Detachment
Evaluation of Visual Functions After Pars Plana Vitrectomy With and Without Internal Limiting Membrane Peeling in RRD
Internal limiting membrane peeling is performed during vitrectomy for macular diseases such as macular holes, macular edema due to diabetic retinopathy and retinal vein occlusion.
- Trial name
- NCT04139811
- Testing
- Pars Plana Vitrectomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
Rhegmatogenous Retinal Detachment
Topographic Changes of Retinal Layers After Resolution of Acute Retinal Detachment
Experimental retinal detachment and reattachment models have demonstrated the recovery process of successfully reattached retina.
- Trial name
- NCT01587794
- Volunteers
- 21 people
- Sponsor
- Samsung Medical Center
Retinal Detachment
Ursodeoxycholic Acid (UDCA) as a Neuroprotective Adjuvant Treatment to Rhegmatogenous Retinal Detachment Surgery
This study is indicated for patients with extended rhegmatogenous retinal detachment (RRD) (≥ 2 quadrants) with macula OFF lasting 7 days or less, pseudophakic or aphakic, and scheduled to undergo surgical intervention with…
- Trial name
- UDCA (NCT06294847)
- Testing
- Ursolvan
- Where
- 2 sites in France
- Volunteers
- 120 people
- Sponsor
- Hopital Foch
Cystoid Macular Edema
Cystoid Macular Edema After Vitrectomy for Rhegmatogenous Retinal Detachment
To investigate the incidence of cystoid macular edema in eyes with primary rhegmatogenous retinal detachment successfully treated with vitrectomy with gas tamponade, and to evaluate the clinical variables associated with its…
- Trial name
- NCT05069675
- Testing
- vitrectomy
- Where
- 6 sites in Italy
- Volunteers
- 2,000 people
- Sponsor
- University of Catania
Retinal Detachment Rhegmatogenous, ILM Peeling
1ry Versus 2ry ILM Peeling in RD
Patients with uncomplicated rhegmatogenous retinal detachment will be recruited. All eyes will underwent 23G PPV with silicon oil tamponade. The eyes will be classified into two groups according to the timing of ILM peeling.
- Trial name
- NCT07346560
- Testing
- Primary ILM peeling, Secondary ILM peeling
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Rhegmatogenous Retinal Detachment, Proliferative Vitreoretinopathy
Topical Netarsudil for the Prevention of Proliferative Vitreoretinopathy in Patients With Retinal Detachment
This study has two main objectives. The first objective is to study the pharmacokinetics of topical netarsudil administration in the posterior segment of the eye, where netarsudil must exert its effect in order to prevent…
- Trial name
- NCT06033703
- Testing
- Netarsudil Ophthalmic
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Retinal Detachment Multiple Breaks
Redetachment Under Densiron for RD Multiple Breaks
Densiron is used as a tamponading agent for inferior retinal detachment with inferior retinal breaks However, data about the use of Densiron -68 for RRD with multiple retinal breaks; especially if involving both superior and…
- Trial name
- Densiron (NCT05716971)
- Testing
- Densiron-68 (heavy silicone oil) tamponade for retinal detachment
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Dar El Oyoun Hospital