Clinical trials: Residual Kidney Function
Chronic Disease, Kidney Diseases
A Study to Evaluate Whether Correction of Anemia Using Recombinant Human Erythropoietin Reduces the Progression of Atherosclerosis and Cardiac Hypertrophy in Pre-dialysis Chronic Kidney Disease Patients
The primary aim of the study is to evaluate the effects of correction of anemia using erythropoietin on the progression of atherosclerosis and cardiac muscle thickening in patients with chronic kidney disease
- Conditions
- Chronic Disease, Kidney Diseases, Cardiovascular Diseases
- Trial name
- NCT00563355
- Testing
- erythropoietin
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Hospital Authority, Hong Kong
Chronic Kidney Disease (Stages 4 and 5), Chronic Kidney Disease 5D
The Practicality and Utility of Measured vs Estimated GFR in adCKD
The goal of this observational study is to assess if new ways of measuring kidney function can better predict when individuals will become symptomatic due to kidney failure, and whether residual kidney function can be accurately…
- Trial name
- NCT07450534
- Testing
- Iohexol Inj 300 MG/ML Diagnostic aid/agent used to measure glomerular filtration rate (GFR)
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Manchester University NHS Foundation Trust
Kidney Failure, Chronic, Heart Failure
Empagliflozin in ESKD - A Feasibility Study
The aim of this study is to learn about the safety of empagliflozin in dialysis patients as a preparation for a future large clinical trial.
- Trial name
- NCT05687058
- Testing
- Empagliflozin 25 mg thrice-weekly post-hemodialysis dosing, Empagliflozin 10 mg daily dosing
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- University of Mississippi Medical Center
Chronic Renal Failure
Initiative for Patient Outcomes in Dialysis - Peritoneal Dialysis (PD) (IPOD-PD Study)
The aim of the study is to asses the hydration status of incident peritoneal dialysis (PD) patients and its evolution over a period of four years, independent of the PD treatment modality (APD or CAPD) and the PD solution type.
- Trial name
- IPOD-PD (NCT01285726)
- Testing
- Non-interventional study
- Where
- 134 sites in Austria, Belgium and 26 more
- Volunteers
- 1,092 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Diuretic Abuse
Use of Diuretics in Maintenance Hemodialysis Patients Undergoing Bioimpedance-guided Fluid Management
Background.The objective of the present study is to verify whether using diuretics will improve either blood pressure or fluid overload in maintenance hemodialysis patients with residual diuresis kidney function.
- Trial name
- NCT04182854
- Testing
- Furosemid hydrochlorothiazide
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Capital Medical University
Kidney Failure, Chronic, Quality of Life
Twice vs Thrice Weekly Hemodialysis: Clinical Outcomes and Quality of Life
This prospective cohort study aims to compare clinical outcomes and health-related quality of life between adults receiving established twice-weekly versus thrice-weekly maintenance hemodialysis at Assiut University Hospitals.
- Trial name
- NCT07821788
- Volunteers
- 130 people
- Sponsor
- Assiut University
Hemodialysis Complication
Impact of Residual Renal Function on Complications in Chronic Hemodialysis Patients
Our aim is to study the impact of residual renal function on hemodialysis patients mortality and morbidity .
- Trial name
- NCT03854513
- Testing
- dialysis machine
- Volunteers
- 100 people
- Sponsor
- Assiut University
Chronic Kidney Insufficiency, Hemodialysis Treatment
Clinical Trial to Compare Effectiveness of Diuretics in Hemodialysis Patients With Residual Renal Function
Introduction: Chronic kidney disease is characterized by a progressive deterioration of renal function. At the end of the progression, when complications occur (overhydration, electrolyte imbalances or retention of uremic…
- Conditions
- Chronic Kidney Insufficiency, Hemodialysis Treatment, Diuresis Preserved
- Trial name
- RRF (NCT01977430)
- Testing
- Hydrochlorothiazide and furosemide
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Corporacion Parc Tauli
Hemodialysis, Kidney Failure, Chronic
Efficacy of Twice Weekly Hemodialysis in Patients With Residual Kidney Function
The study will determine the efficacy of twice weekly hemodialysis in patients with residual kidney function.
- Trial name
- NCT03874117
- Testing
- Twice Weekly Hemodialysis then Thrice Weekly Hemodialysis, Thrice Weekly Hemodialysis then Twice Weekly Hemodialysis
- Where
- 3 sites in United States
- Volunteers
- 58 people
- Sponsor
- Palo Alto Veterans Institute for Research
End-Stage Renal Disease, Type 2 Diabetes Mellitus
A Double-Blind, Randomized, Placebo-Controlled Safety Study Evaluating the Effects of Residual Renal Function (RFF) in Patients With End-Stage Renal Disease and Type 2 Diabetes Mellitus on Peritoneal Dialysis
This study is a multi-center, double-blinded, randomized, study of bardoxolone methyl treatment in patients with End-Stage Renal Disease (ERSD) and Type 2 Diabetes Mellitus (T2DM) on peritoneal dialysis.
- Trial name
- NCT01576887
- Testing
- Bardoxolone Methyl 20 mg
- Sponsor
- Biogen
End-stage Renal Disease (ESRD)
NIRS for the Diagnosis of Residual Renal Function Injury in Hemodialysis Patients
Hemodialysis (HD) is the main renal replacement therapy for patients with end-stage renal disease (ESRD), accounting for approximately 69% of all renal replacement therapies and 89% of all dialysis.
- Trial name
- HDRRFI-NIRS (NCT06243900)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Yuanjun Yang
Chronic Kidney Disease (CKD) Stage 5, Kidney Dysfunction Requiring Dialysis (KDRD)
Incremental Hemodialysis for Veterans in the First Year of Dialysis (IncHVets)
In this pragmatic clinical trial, which will dovetail with Veterans' routine outpatient dialysis clinic visits in six VA medical centers, the investigators will study 252 Veterans with kidney disease who need to start dialysis…
- Conditions
- Chronic Kidney Disease (CKD) Stage 5, Kidney Dysfunction Requiring Dialysis (KDRD), Dialysis Dependency
- Trial name
- INCHVETS (NCT05465044)
- Testing
- Twice-weekly hemodialysis with incremental crossover to thrice-weekly schedule, Thrice-Weekly Hemodialysis
- Where
- 8 sites in United States
- Volunteers
- 252 people
- Sponsor
- VA Office of Research and Development
Kidney Function, Hemodialysis
Effects of Low Protein Diet Supplemented With Ketoanalogues on Preservation of Kidney Function in Incremental Dialysis
The investigators hypothesized that combination of incremental hemodialysis and ketoanologues will better preserve residual kidney function and maintenance of nutritional status among the incident ESRD patients during the early…
- Trial name
- NCT05030168
- Testing
- Ketosteril
- Volunteers
- 50 people
- Sponsor
- Chulalongkorn University
Renal Function Disorder
Renal Protective Effects of Restricted Protein Dietary With α-keto Acid in CAPD Patients
The prospective, double blind randomized, parallel control, and multi-center clinical trial will evaluate the safety and efficacy of α-keto acid with restricted protein diet on protecting residual renal function in continuous…
- Trial name
- NCT01255020
- Testing
- α-Keto Acid with restricted protein diet
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Sun Yat-sen University
Chronic Renal Disease
Residual Renal Function Preservation in Peritoneal Dialysis Patients
Aldosterone blockade is useful in preserving residual renal function in patients on PD.The long term efficacy of dual blockade of the RAAS is better than monotherapy.
- Trial name
- NCT02190318
- Testing
- Losartan, spirolactone, blank control
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Second Xiangya Hospital of Central South University
Loss of Residual Renal Function, Technique Failure in Peritoneal Dialysis
Peritonitis and Loss of Residual Renal Function, Technique Failure and Mortality in Peritoneal Dialysis Patients
The primary objective is to analyze peritonitis rate and peritonitis bacteriology as risk factors for loss of residual renal function, technique failure and mortality in chronic kidney disease patients.
- Trial name
- NCT01977716
- Where
- Mexico
- Volunteers
- 350 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Uremia
L-Cysteine in Peritoneal Dialysis
Over the last decades, peritoneal dialysis has grown worldwide to become one of the most common modalities of renal replacement therapy, particularly in developing or newly industrialized countries, such as India, China, Korea…
- Trial name
- CINDY (NCT02050139)
- Testing
- L-cysteine
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Chronic Kidney Disease, Congestive Heart Failure
Peritoneal Ultrafiltration to Treat Congestive Heart Failure
The purpose of this study is to determine whether the treatment of peritoneal ultrafiltration can improve survival and quality of life of refractory congestive heart failure with special accent on preserving residual renal…
- Trial name
- NCT02829450
- Testing
- peritoneal ultrafiltration
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Soroka University Medical Center
End-stage Renal Disease
The Protective Effect of Remote Ischemic Conditioning on Residual Renal Function in Hemodialysis Patients (RIC-HD)
Hemodialysis (HD) is the main renal replacement therapy for patients with end-stage renal disease. However, factors such as hemodynamic instability can lead to gradual loss of residual renal function (RRF) in HD patients.
- Trial name
- RIC-HD (NCT06275152)
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Yuanjun Yang
Peritoneal Dialysis
Study to Evaluate the Protective Effect of α-Keto Acid With Low-protein Diet on Renal Function in PD Patients
This randomized, open-label, prospective study will evaluate the renal effective effect of compound α-Keto Acid plus low protein diet in PD Patients.
- Trial name
- NCT00734552
- Testing
- α-Keto Acid with low protein diet, Normal protein diet
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University