Clinical trials: Resection
Lung Cancer, Nutrition, Healthy
The Effect of Nutritional Risk Parameters on Postoperative Pulmonary Complications in Geriatric Thoracic Surgery Cases
Preoperative evaluation of nutritional status in geriatric patients with lung cancer and implementation of these practices in elective patients are very important in terms of reducing postoperative complications and accelerating…
- Conditions
- Lung Cancer, Nutrition, Healthy, Postoperative Complications
- Trial name
- NCT05890820
- Testing
- Preoperative nutritional assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Breast-Conserving Surgery, Breast Carcinoma
Comparative Research on the Accuracy of Margin Interpretation in Breast-Conserving Surgery for Breast Cancer: Cell Microscopic Imaging and Standard Frozen Pathology
The goal of this clinical trial is to assess whether cell microscopic imaging can accurately determine the tumor-free status of surgical margins in breast cancer patients undergoing breast-conserving surgery.
- Conditions
- Breast-Conserving Surgery, Breast Carcinoma, Margins in the Specimen
- Trial name
- NCT07029646
- Testing
- EndoScell™ intraoperative handheld microscope
- Volunteers
- 167 people
- Sponsor
- Peking University Cancer Hospital & Institute
Urinary Bladder Cancer
Intravesical Gem/Doce in Patients With NMIBC
Intravesical immunotherapy or chemotherapy for non-muscle invasive bladder cancer (NMIBC) is a well-established treatment for preventing or delaying tumor recurrence after tumor resection.
- Trial name
- NCT05644041
- Testing
- gemcitabine + docetaxel
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Arizona
Right Ventricular Dysfunction, Pneumonectomy; Status
Right Ventricle Function After Major Right Lung Resection
Major lung resection is associated with high post-operative morbidity and mortality and significant long-term decreased functional capacity, especially due to cardiorespiratory complications.
- Trial name
- RIVER (NCT04167241)
- Testing
- Echocardiography
- Volunteers
- 50 people
- Sponsor
- Humanitas Clinical and Research Center
Colorectal Cancer, Liver Metastases
Treatment Strategies in Colorectal Cancer Patients With Initially Unresectable Liver-only Metastases
Colorectal cancer patients with initially unresectable liver-only metastases may be cured after downsizing of metastases by neoadjuvant systemic therapy.
- Trial name
- CAIRO5 (NCT02162563)
- Testing
- FOLFOX/ FOLFIRI with bevacizumab, FOLFOXIRI with bevacizumab, FOLFOX/ FOLFIRI with panitumumab
- Where
- 56 sites in Belgium, Netherlands
- Volunteers
- 530 people
- Sponsor
- Dutch Colorectal Cancer Group
Rectal Cancer
Fluorescent Lymphography-Guided Lymphadenectomy In Laparoscopic Proctectomy
The purpose of this study is to compare the number of lymph nodes retrieved with or without the use of intraoperative fluorescence lymphography in laparoscopic radical resection of rectal cancer.
- Trial name
- NCT03854890
- Testing
- Indocyanine Green
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fudan University
Rectal Cancer Patients
Validation of the French Version of the Low Anterior Resection Syndrome (LARS) Among Rectal Cancer Patients
Oncological rectal cancer outcomes have improved considerably because of optimal surgery by total mesorectal excision in conjunction with multidisciplinary team management by selective multimodal therapy (ie, neo-adjuvant…
- Trial name
- LARS (NCT03569488)
- Testing
- FT-LARS questionnaire
- Where
- 8 sites in France
- Volunteers
- 1,100 people
- Sponsor
- University Hospital, Caen
Gastroenterology
Outcome of Colonoscopy Screening and Surveillance
With this study, we plan to review the performance of colonoscopy in colon cancer screening and surveillance, especially with the recent improvements in endoscopic technology (high definition endoscopes), use of split dose…
- Trial name
- NCT01827241
- Testing
- Chart Review
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Ankle Fractures
Hardware Removal After ORIF of Ankle Fractures
Ankle fractures account for 10 % of fractures in the adult population. A part of patients (40%) is treated surgically. After healing of the fractures, about one year after the operation, a surgery is often performed to remove the…
- Trial name
- NCT05798741
- Testing
- Hardware removal
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Hôpital Fribourgeois
Mandibular Neoplasms
Inferior Alveolar Nerve Block for Intraoperative Analgesia for Maxillofacial Cancer Surgery - RCT
Mandibular resection which is an important component of maxillofacial cancer surgery is an extremely painful procedure associated with severe sympathetic response needing high doses of opioids.
- Trial name
- NCT02745288
- Testing
- inferior alveolar nerve block
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Tata Memorial Centre
Colorectal Cancer
Robotic Top-down Intersphincteric Resection
The present study is to develop the novel robotic surgical technique and enhance the surgery quality for the treatment of distal rectal cancer.
- Trial name
- NCT05961969
- Testing
- Robotic surgery
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Mechanical Ventilation With Oral Intubation, Weaning Invasive Mechanical Ventilation
Endotracheal Suctionning During Positive Pressure Extubation in ICU
The aim of this clinical trial is to evaluate endotracheal suctioning during positive pressure extubation in mechanically ventilated adult patients (over 18 years old) in the intensive care unit (ICU).
- Conditions
- Mechanical Ventilation With Oral Intubation, Weaning Invasive Mechanical Ventilation, Oxygen Saturation Measurement, Rox Index
- Trial name
- INTENTION (NCT07130123)
- Testing
- Suctionning extubation, No suctionning Extubation
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Stage IB Non-Small Cell Lung Carcinoma AJCC v7, Stage II Non-Small Cell Lung Cancer AJCC v7
Cisplatin, Docetaxel, and Nintedanib Before Surgery in Treating Patients With Previously Untreated Stage IB-IIIA Non-small Cell Lung Cancer
This phase I trial studies the side effects and best dose of nintedanib when given together with cisplatin and docetaxel and to see how well they work in treating patients with previously untreated stage IB-IIIA non-small cell…
- Conditions
- Stage IB Non-Small Cell Lung Carcinoma AJCC v7, Stage II Non-Small Cell Lung Cancer AJCC v7, Stage IIA Non-Small Cell Lung Carcinoma AJCC v7, Stage IIB Non-Small Cell Lung Carcinoma AJCC v7
- Trial name
- NCT02225405
- Testing
- Cisplatin, Docetaxel, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- M.D. Anderson Cancer Center
Pancreatitis, Acute, Bleeding
Quick Large Balloon Dilatation for Removal of Large Bile Duct Stones (SHODBADI)
ESGE guidelines suggests 30-60 seconds endoscopic large balloon papillary dilation from the disappearance of the waist of the papilla.
- Conditions
- Pancreatitis, Acute, Bleeding, Cholangitis
- Trial name
- SHODBADI (NCT05061680)
- Testing
- endoscopic short duration papillary large balloon dilation
- Where
- 2 sites in Finland
- Volunteers
- 600 people
- Sponsor
- Helsinki University Central Hospital
Aortic Valve Stenosis
Nitinol Circular Blade
The Nitinol Circular Blade (NCB) is indicated for use in patients with symptomatic aortic stenosis requiring aortic valve replacement, who are going to be operated by conventional sternotomy with native valve resection and…
- Trial name
- NCB (NCT03881527)
- Testing
- Aortic valve replacement using a nitinol blade, aortic valve replacement
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Penicillin Allergy
The Effect of Providing Stratification of Low Risk Penicillin Allergies on Penicillin Allergy Label Removal
Currently it is estimated that at least 25 million people in the United States are labeled as penicillin allergic although less than 1.5 million of these are truly allergic.
- Trial name
- NCT03702270
- Testing
- Penicillin Allergic Risk Stratification Best Practice Alert
- Where
- United States
- Volunteers
- 2,052 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Hepatocellular Carcinoma, Cirrhosis
Estimation of Functional Liver Reserve Using Cholinesterases
Estimation of functional liver reserve in patients with hepatocellular carcinoma (HCC) in cirrhosis is of paramount importance to properly select candidates for surgical resection.
- Conditions
- Hepatocellular Carcinoma, Cirrhosis, Liver Neoplasm, Liver Disease
- Trial name
- NCT00883454
- Where
- Italy
- Volunteers
- 181 people
- Sponsor
- University of Milan
Colorectal Liver Metastasis
Minimally Invasive Versus Open Liver Resection for Patients With Colorectal Cancer Liver Metastases
To examine survival of patients who underwent minimally invasive versus open liver resection for colorectal cancer with liver metastases.
- Trial name
- NCT03895723
- Testing
- laparoscopic and robotic liver resection, open surgery
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Xu jianmin
Rectum Cancer
The Role of Pelvic Peritonization in Laparoscopic or Robotic Low Anterior Resection
A randomized controlled clinical trial to compare the short and long outcomes of low anterior resection for middle-low rectal cancer with or without pelvic peritonization.
- Trial name
- NCT03699761
- Testing
- Closure of the pelvic peritoneum, Nonclosure of the pelvic peritoneum
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Southwest Hospital, China
Hepatocellular Carcinoma
A Study of Camrelizumab Plus Apatinib as Adjuvant Therapy in Patients With Hepatocellular Carcinoma at High Risk of Recurrence After Radical Resection or Ablation
The goal of this clinical trial is to evaluate the efficacy and safety of camrelizumab plus apatinib as adjuvant therapy for patients with hepatocellular carcinoma at high risk of recurrence after radical resection or ablation.
- Trial name
- NCT06546280
- Testing
- Camrelizumab, Apatinib
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Zhujiang Hospital