Clinical trials: Renal Failure, End Stage
End Stage Renal Disease, Myocardial Microvascular Disease
Myocardial Microvascular Disease in ESRD
Cardiovascular diseases are the leading cause of mortality in patients with end stage renal disease (ESRD). They often have myocardial ischemia (a major predictor of mortality) on non invasive testing (Stress echocardiography…
- Trial name
- MICROCARD (NCT01291771)
- Testing
- Invasive FFR + CFR measurements are performed during coronary angiography using a pressure guide wire
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
End Stage Renal Disease
Safety and Efficacy of Acthar Gel in an Outpatient Dialysis Population
This will be a prospective observational study of Acthar Gel in Non-Diabetic Hemodialysis [NDHD] patients receiving dialysis for ≤ 2 years.
- Trial name
- NCT02486744
- Testing
- Acthar Gel
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Youngstown State University
Renal Insufficiency, Chronic, Kidney Failure, Chronic
Effects of a Mindfulness-based Intervention in Stress, Pain and Quality of Life in People Undergoing Hemodialysis
This project has as main objective to evaluate the effects of a Mindfulness-based intervention (MBI) in the reduction of stressors, pain and quality of life of people with chronic kidney disease undergoing hemodialysis (HD).
- Conditions
- Renal Insufficiency, Chronic, Kidney Failure, Chronic, Kidney Diseases, Kidney Insufficiency, Chronic
- Trial name
- NCT04610593
- Testing
- Mindfulness-based Intervention
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
End Stage Renal Disease
A Study of Drug-Induced Kidney Disease
The purpose of this study is to identify incidence of Chinese herb nephropathy in a medical center
- Trial name
- NCT00729014
- Where
- Taiwan
- Volunteers
- 2,000 people
- Sponsor
- National Taiwan University Hospital
End Stage Renal Disease on Dialysis, Hemodialysis
Interdialytic Peritoneal UltraFiltration in HemoDialysis Patients
Sodium accumulates in the tissues of patients with kidney disease and impairs survival. Three-times weekly, standard hemodialysis alone cannot remove excess sodium efficiently.
- Conditions
- End Stage Renal Disease on Dialysis, Hemodialysis, Peritoneal Dialysis, Nonosmotic Sodium Storage
- Trial name
- IPUF-HD (NCT04603014)
- Testing
- Interdialytic peritoneal ultrafiltration with 10% dextrose solution
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
End-stage Renal Disease, Chronic Kidney Disease
Acupuncture for Pain Management of Hemodialysis Patients
The purpose of this study is to determine the feasibility, effectiveness and safety of acupuncture for pain management in hemodialysis patients.
- Trial name
- NCT01102816
- Testing
- Individualized acupuncture treatment, Routine care
- Where
- 2 sites in South Korea
- Volunteers
- 1 people
- Sponsor
- Korea Institute of Oriental Medicine
Chronic Kidney Diseases, Major Depressive Disorder
Combination of Novel Therapies for CKD Comorbid Depression
The overall goal of the study is to determine if treatment of a Major Depressive Disorder (MDD) improves the outcomes of patients with chronic kidney disease (CKD).
- Conditions
- Chronic Kidney Diseases, Major Depressive Disorder, End Stage Kidney Disease (ESRD)
- Trial name
- CONCORD (NCT04422652)
- Testing
- Bupropion, Behavioral activation therapy, Clinical Management
- Where
- 4 sites in United States
- Volunteers
- 201 people
- Sponsor
- Stony Brook University
End Stage Renal Disease
SPIRIT for Persons With Dementia and Complex Multimorbidity
In this study, 30 patient and caregiver dyads will be randomized to receive the SPIRIT-dementia intervention or usual care. Participants will be follow-up with 2-3 days after the intervention to evaluate the impact of SPIRIT on…
- Trial name
- NCT04108000
- Testing
- SPIRIT-Dementia, Usual Care
- Where
- 4 sites in United States
- Volunteers
- 38 people
- Sponsor
- Emory University
Hemodialysis, End Stage Renal Disease Requiring Hemodialysis
Pharmacist-led Intervention on Hemodialysis Patients' Therapy Adherence
A parallel-group, cluster-randomized, controlled trial designed to evaluate if hemodialysis patients benefit from BCT. The study includes two groups: usual care and pharmacist-led intervention groups.
- Trial name
- NCT06744738
- Testing
- Pharmacist led behavioral change technique
- Where
- Iraq
- Volunteers
- 72 people
- Sponsor
- Thuraya Safaa Ibrahim
End-Stage Kidney Disease (ESKD)
Pharmacokinetics of Oral Letermovir in Adults With End-Stage Kidney Disease With or Without Haemodialysis
This study aims to understand how the antiviral medication letermovir (PREVYMIS) is processed by the body in adults with end-stage kidney disease (ESKD), including those who are receiving intermittent haemodialysis and those who…
- Trial name
- NCT07101055
- Testing
- Letermovir 480 mg [PREVYMIS]
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jason A Roberts
End-Stage Renal Disease, Stage 5 Chronic Kidney Disease
Effect of Dialysis on the Pharmacokinetics of Telavancin in Patients With Chronic Kidney Disease Stage 5
Chronic Kidney Disease Stage 5 (CKD5) patients receiving maintenance hemodialysis are at an increased risk for developing bloodstream infections.
- Trial name
- NCT02392208
- Testing
- Telavancin, Pharmacokinetic Blood Sampling
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Michigan
End Stage Renal Disease
HeRO Vascular Access Device Post Market Procedural Survey Protocol
Post market observational survey of a vascular access device for access-challenged patients. Data collection efforts focused on patient medical and access history and implant procedure results.
- Trial name
- PPS (NCT00889291)
- Volunteers
- 77 people
- Sponsor
- Merit Medical Systems, Inc.
Chronic Kidney Disease, End-stage Renal Disease (ESRD)
Effect of Intradialytic Eating Timing on Hemodynamic Stability and Dialysis Adequacy in Hemodialysis Patients
This study aims to examine how different meal timing during hemodialysis affects blood pressure stability and dialysis effectiveness in patients with chronic kidney disease.
- Conditions
- Chronic Kidney Disease, End-stage Renal Disease (ESRD), Hemodialysis
- Trial name
- IDE-HD (NCT07464418)
- Testing
- Intradialytic Eating Timing Intervention
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Muhammadiyah Surakarta
End Stage Renal Failure on Dialysis, End Stage Renal Disease on Dialysis
Human Factors Validation Testing for the Peripal System; a Manual Connection Assist Device for Peritoneal Dialysis Devices
It is estimated that there are currently over 3 million patients receiving dialysis treatment worldwide. With effective pre-dialysis counselling, a majority of patients choose the home-based therapy peritoneal dialysis (PD) but…
- Conditions
- End Stage Renal Failure on Dialysis, End Stage Renal Disease on Dialysis, Renal Failure, Peritoneal Dialysis
- Trial name
- NCT04292210
- Testing
- Perisafe
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Peripal AG
Chronic Renal Failure, Hemodialysis
Effects of Shenkang Decoction on Creatinine and Blood Urea Nitrogen in Chronic Renal Failure Hemodialysis Patients
To explore the clinical effect of Shenkang Decoction in chronic renal failure (CRF) patients with hemodialysis (HD).
- Trial name
- NCT05631782
- Testing
- Shenkang decoction
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The First People's Hospital of Zunyi
End Stage Renal Disease, Nutrition
Endocannabinoids in End Stage Renal Disease
To investigate the relationship between dietary intake, body habitus, and endocannabinoid levels in end stage renal disease patients as compared to matched controls.
- Trial name
- NCT01477515
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana University
Uremic Pruritus
Phase 1 Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritus
This is a single-center clinical research study with the purpose to evaluate the safety, tolerability, and pharmacokinetics (PK) of nalbuphine HCl ER (extended release) tablets in end-stage renal disease (ESRD) patients receiving…
- Trial name
- NCT02373215
- Testing
- Nalbuphine HCL ER
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Trevi Therapeutics
Kidney Failure, Chronic
Resistance Training and Diet in Patients With Chronic Renal Failure
This study will examine the effects of long-term adherence to a low protein diet (LPD) of 0.6 g/kg-1/d-1 with and without progressive resistance exercise training in patients with impaired renal function on body composition…
- Trial name
- NCT00018317
- Testing
- low protein diet, resistance training, combination of diet control and exercise
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Kidney Disease, Kidney Disease, Chronic
Rutgers University Study of the Genetics of Kidney Disease
The goal of this observational study is to learn more about how genes impact the risk of kidney disease. Anyone 18 or older living in the US is eligible, and a diagnosis of kidney disease is NOT required.
- Conditions
- Kidney Disease, Kidney Disease, Chronic, Kidney Disease, End-Stage, Kidney Diseases
- Trial name
- rugcc-kd (NCT07217535)
- Testing
- Saliva sample, Health surveys
- Where
- United States
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
End Stage Renal Failure
Gengraf Conversion Study in Stable Renal Allograft Transplant Recipients
The purpose of this study is to establish the therapeutic equivalence of Gengraf® with the standard treatment Neoral® for a treatment period of 6 months in stable renal allograft transplant recipients with respect to drug levels…
- Trial name
- NCT01990118
- Testing
- Neoral, Gengraf® capsule containing 25mg or 100mg cyclosporine
- Where
- Malaysia
- Volunteers
- 106 people
- Sponsor
- Penang Hospital, Malaysia
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