Clinical trials: Renal Dialysis
Chronic Kidney Disease, End-stage Renal Disease
Comparison of High Versus Low Bicarbonate Hemodialysis
This study will compare hemodialysis treatment with a standard, high-bicarbonate dialysis bath versus a lower bicarbonate dialysis bath, and will compare intradialytic acid-base changes and overall control of metabolic acidosis…
- Conditions
- Chronic Kidney Disease, End-stage Renal Disease, Metabolic Acidosis
- Trial name
- NCT02098356
- Testing
- Low Bicarbonate
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Albert Einstein College of Medicine
Peritoneal Dialysis
A Multi-center Prospective Cohort Study Based on Peritoneal Dialysis Telemedicine-assisted Platform
Increasing the proportion of patients on peritoneal dialysis (PD) may relieve the financial burden caused by the growing number of patients with end-stage renal disease (ESRD).
- Trial name
- PDTAP (NCT03571451)
- Where
- 27 sites in China
- Volunteers
- 7,000 people
- Sponsor
- Peking University First Hospital
Secondary Hyperparathyroidism
Cinacalcet in Paediatric Secondary Hyperparathyroidism (SHPT) Due to Chronic Kidney Disease (CKD)
Twelve-month, multicenter, intra-subject controlled (retrospective-prospective), open-label, active-treatment study to evaluate the dose-response and pharmacokinetics (PK) of cinacalcet HCl for the treatment of Secondary…
- Trial name
- NCT01479088
- Testing
- Cinacalcet HCl
- Where
- 5 sites in Italy
- Volunteers
- 30 people
- Sponsor
- ENRICO VERRINA
To Determine the Prevalence of Latent Tuberculosis in Each Group, To Monitor the Occurrence of Active Tuberculosis
Surveillance and Follow-up for Latent Tuberculosis Infection and Observation of the Effect of Prophylactic Latent Tuberculosis Treatment in Patients With Severe Chronic Kidney Disease or Receiving Long-term Dialysis
To follow-up the latent tuberculosis infection and evaluate the risk of developing active tuberculosis in patients with severe chronic kidney disease or receiving long-term dialysis
- Trial name
- NCT01685086
- Where
- Taiwan
- Volunteers
- 500 people
- Sponsor
- National Taiwan University Hospital
Peritoneal Dialysis-associated Peritonitis, Vitamin D Deficiency
Oral Vitamin D Supplementation Prevent Peritoneal Dialysis-related Peritonitis
This is a multicenter randomized, placebo-controlled trial of Vitamin D supplementation in patients on peritoneal dialysis to determine whether oral administration of vitamin D3 after curing an episode of peritonitis could reduce…
- Trial name
- VD-PD (NCT05860270)
- Testing
- Cholecalciferol
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Peking University First Hospital
End Stage Renal Disease, Thrombosis
Access II - Trial of Warfarin to Prevent Malfunction of Haemodialysis Catheters
This study examines whether low intensity, dose adjusted warfarin prolongs the time to mechanical failure of hemodialysis catheters without resulting in an unacceptable rate of bleeding.
- Conditions
- End Stage Renal Disease, Thrombosis, Bleeding
- Trial name
- NCT00157651
- Testing
- warfarin
- Where
- Canada
- Volunteers
- 170 people
- Sponsor
- Hamilton Health Sciences Corporation
Critical Lower Limb Ischemia, Critical Limb Ischemia
Evaluation of Carbothera in the Treatment of Foot Ulcers
Foot ulceration usually precedes more serious foot complications such as infection, gangrene or amputation. The risk of developing foot ulcers has been estimated to be higher in individuals with kidney disease.
- Conditions
- Critical Lower Limb Ischemia, Critical Limb Ischemia, Foot Ulcer, Skin Ulceration
- Trial name
- NCT02239419
- Testing
- CO2-Enriched Tap Water (Carbothera), Non-CO2-Enriched Tap Water
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Anemia in Chronic Kidney Disease Patients Not on Dialysis
Strategies Using Darbepoetin Alfa to Avoid Transfusions in Chronic Kidney Disease
A phase 3, multicenter, randomized, double-blind, parallel group study. Anemic subjects with chronic kidney disease (CKD) and not on dialysis will be randomized 1:1 to 1 of 2 dosing strategies to evaluate the proportion of…
- Trial name
- START-CKD (NCT01652872)
- Testing
- Darbepoetin alfa
- Where
- 249 sites in United States, Puerto Rico
- Volunteers
- 756 people
- Sponsor
- Amgen
Haemodialyzed Patients, Hyperphosphatemia
Arterial Stiffness and Calcifications in Haemodialysis Patients on Sevelamer or Calcium Acetate
End-stage renal disease (ESRD) is a state of increased arterial stiffness of extensive vessel calcifications, compared with the non-renal population.
- Trial name
- NCT00364000
- Testing
- Calcium acetate, Sevelamer
- Where
- 2 sites in Romania
- Sponsor
- Romanian Society of Nephrology
Chronic Kidney Disease
Study to Compare Palindrome vs. BioFlo DuraMax Dialysis Catheters
Numerous catheter designs have been studied to increase efficacy and minimize complications of catheter hemodialysis. Major complications of catheters include thrombosis, central venous stenosis, infection, and dialysis…
- Trial name
- NCT02796300
- Testing
- Bioflo Dialysis Catheter, Palindrome Dialysis Catheter
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, Los Angeles
Diuretic Abuse
Use of Diuretics in Maintenance Hemodialysis Patients Undergoing Bioimpedance-guided Fluid Management
Background.The objective of the present study is to verify whether using diuretics will improve either blood pressure or fluid overload in maintenance hemodialysis patients with residual diuresis kidney function.
- Trial name
- NCT04182854
- Testing
- Furosemid hydrochlorothiazide
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Capital Medical University
Dialysis; Complications
Effect of Sodium and UF Profiling on Dialysis
The aim of this study is to evaluate the effects of sodium and UF profiling on hemodynamic stability, interdialytic weight gain, and intradialytic complications
- Trial name
- NCT06213129
- Testing
- Na and ultrafiltration profiling
- Volunteers
- 30 people
- Sponsor
- Assiut University
Kidney Disease, End-Stage
Electronic Patient-Reported Outcomes in Clinical Kidney Practice (ePRO Kidney)
People living with end-stage kidney disease (ESKD) need dialysis or transplantation in order to stay alive. This illness and treatment significantly impact peoples' health, emotions, work and relationships.
- Trial name
- NCT03149328
- Testing
- Educational Support
- Where
- 2 sites in Canada
- Volunteers
- 594 people, healthy volunteers welcome
- Sponsor
- University of Alberta
End Stage Renal Disease
Peridialysis Project: The Influence of Predialysis Factors on the Initial Course of Dialysis
The present study plans to delineate the clinical, biochemical, sociological and psychological factors. involved in dialysis preparation, and their impact on dialysis initiation (DI), modality choice and prognosis.
- Trial name
- Peridialysis (NCT02488200)
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 1,400 people
- Sponsor
- Herlev Hospital
Acute Kidney Injury
Online Hemodiafiltration vs Conventional Hemodialysis in Acute Kidney Injury
Only limited data exist on the benefit of online hemodiafiltration in patient with Acute kidney injury. The objective of this pilot RCT is to assess the feasibility of a large multicentre RCT to determine whether, in patients…
- Trial name
- HDFAKI (NCT04525092)
- Testing
- Online Pre-dilution Hemodiafiltration, Conventional Hemodialysis, Online Post-dilution Hemodiafiltration
- Where
- 2 sites in Canada, Ireland
- Volunteers
- 45 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Hemodialysis Patients
The Effect of Horticultural Therapy on Stress, Well-Being, and Care Burden in Hemodialysis Caregivers
This research is a randomized controlled single-blind experimental study aiming to evaluate the effect of horticultural therapy on stress, well-being, and caregiver burden among caregivers of hemodialysis patients.
- Trial name
- NCT07188792
- Testing
- HORTICULTURAL THERAPY
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Ataturk University
Chronic Kidney Disease
Behavioral AI to Predict and Increase Peritoneal Dialysis Uptake
Scaled Insights Behavioral AI will be used to improve clinicians ability to detect and understand: The likelihood of patients with kidney failure opting for peritoneal dialysis and to select the right personalized nudge to get…
- Trial name
- AI (NCT06533254)
- Testing
- Predicting choice of dialysis, Behavioral nudges
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Scaled Insights
Diabetic Nephropathy Type 2, Type2 Diabetes
Glycaemic Markers in Persons With Type 2 Diabetes on Haemodialysis
To investigate the correlation between the mean glucose concentration measured by continuous glucose monitoring (CGM) and the estimated mean blood glucose from glycated haemoglobin A1c (HbA1c) in persons with type 2 diabetes and…
- Trial name
- GLYCOHEMO (NCT03909269)
- Testing
- Continuous glucose monitoring, Glycaemic markers, Erythrocyte life span
- Where
- Denmark
- Volunteers
- 88 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acute Kidney Injury, Kidney; Disease, Acute
Liberation From Acute Dialysis
The goal of the LIBERATE-D clinical trial is to improve outcomes for patients recovering from dialysis-requiring acute kidney injury (AKI-D).
- Conditions
- Acute Kidney Injury, Kidney; Disease, Acute, Dialysis Related Complication
- Trial name
- LIBERATE-D (NCT04218370)
- Testing
- Dialysis
- Where
- 4 sites in United States
- Volunteers
- 220 people
- Sponsor
- University of California, San Francisco
Kidney Transplant Access, Obese Patients
Access to Kidney Transplant of Obese Patients Beginning Dialysis
Obesity is in constant increase all over the world and affects 35% of the global population according to the World Health Organisation.
- Conditions
- Kidney Transplant Access, Obese Patients, Dialysis, Comorbidities
- Trial name
- Transplantob (NCT04748770)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
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