Clinical trials: Remote Ischaemic Conditioning
Stroke, Acute
Exercise and RIC and TCD
The first week after a stroke is a particularly important time, as improving blood flow may limit secondary ischaemic damage to the brain and help reduce the overall burden neurological injury and future disability.
- Trial name
- NCT03968068
- Testing
- Exercise Procedure, Remote Ischaemic Conditioning
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Healthy Young Adults
Remote Ischemic Conditioning and Spinal Reflex Modulation
Remote ischemic conditioning (RIC) is a clinically feasible method that protects distant organs from severe injury through brief, sub lethal periods of ischemia followed by re-perfusion.
- Trial name
- NCT06860464
- Testing
- Remote Ischemic Condtioning (RIC), Balance training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Central Sympathetic Nervous System Diseases
Role of Sympathetic Activation in Ischemia Reperfusion Injury
This study is designed to assess the effect of forearm ischemia-reperfusion injury on sympathetic nerve activity. To determine whether reduced sympathetic responsiveness is a contributor to the protective effects of remote…
- Trial name
- NCT04479813
- Testing
- Moxonidine 0.2 MG
- Where
- Australia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Royal Perth Hospital
Remote Ischemic Conditioning
The Impact of Serial Remote Ischemic Conditioning on Dynamic Cerebral Autoregulation in Healthy Adults
The purpose of this study is to determine the impact of serial remote ischemic conditioning on dynamic cerebral autoregulation and related hematology indexes in healthy adults.
- Trial name
- NCT04899362
- Testing
- BB-RIC-D1/LAPUL Medical Devices Co, Ltd, China, Intravenous blood collection, dCA measurement
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Jilin University
Anterior Myocardial Infarction, Heart Failure
Effect of Intravenous Metoprolol Combining RIC on Myocardial Protection in STEMI Patients
The main purpose of this study is to compare the myocardial protection effect of intravenous metoprolol combined with remote ischemic conditioning (RIC) and single treatment before reperfusion in Chinese patients with anterior…
- Trial name
- NCT03579914
- Testing
- Metoprolol Injectable Product, Romote Ischemic Conditioning (RIC), Metoprolol & RIC
- Where
- 16 sites in China
- Volunteers
- 1,206 people, healthy volunteers welcome
- Sponsor
- Harbin Medical University
Adults, Older Adults
Effects of RLIC on Motor Learning in Middle-aged and Older Adults
The purpose of this research is to determine if the beneficial effects of remote limb ischemic conditioning on learning seen in young adults are found in middle-aged and older adults.
- Trial name
- NCT03582943
- Testing
- RLIC, Balance training
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Healthy Volunteers
Glucagon Like Peptide-1 in Remote Ischemic Conditioning
The study was designed to investigate whether glucagon like peptide-1 is a mediator of protection of endothelial function induced by remote ischemic conditioning in ischemia-reperfusion
- Trial name
- NCT02746757
- Testing
- Remote conditioning, Exendin 9-39
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Healthy, Young Adults
Effect of Number of Remote Limb Ischemic Conditioning Cycles on Learning Enhancement
The purpose of this research study is to determine the effect of number of remote limb ischemic conditioning (RLIC) cycles on enhancing learning in neurologically intact young adults.
- Trial name
- RLICC (NCT03512041)
- Testing
- RLIC - 5 cycles, RLIC - 4 Cycles, RLIC - 3 Cycles
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
2,3-Bisphosphoglycerate
Effect of RIC on 2,3-BPG in Erythrocyte (RIC-BPG)
Under hypoxia or high-altitude hypoxia ,it has been found that 2,3-bisphosphoglycerate(2,3-BPG) in erythrocyte increased and facilitated oxygen release to tissues.Remote Ischemic Conditioning(RIC) can also cause hypoxic…
- Trial name
- RIC-BPG (NCT04192578)
- Testing
- remote ischemic conditioning
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Hypertension, Vascular Diseases
The Effect of Chronic Remote Ischaemic Preconditioning on Blood Pressure in Older Adults
The purpose of this study is to assess whether remote ischaemic conditioning, applied chronically, improves vascular health in older adults
- Trial name
- RIPCo (NCT05971407)
- Testing
- Remote Ischaemic Preconditioning
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Ischemic Preconditioning
Conditioning Based Intervention Strategies
The overall objective of this study is to uncover and utilize the mechanisms behind the activation of endogenous organ protection by remote ischemic conditioning (RIC), high intensity traditional resistance training (TRT) and low…
- Trial name
- ConBIS (NCT03380663)
- Testing
- Remote Ischemic Conditioning (RIC)
- Where
- Denmark
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Retinal Artery Occlusion, Retinal Vein Occlusion
Changes in the Diameter of Retinal Vessels After Remote Ischemic Conditioning
Remote ischemic conditioning (RIC) is a therapeutic strategy for protecting organs or tissue against the detrimental effects of acute ischemia-reperfusion injury.
- Trial name
- NCT02898480
- Testing
- Remote ischemic conditioning
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Cerebral Autoregulation, Blood Pressure
Remote Ischaemic Conditioning in the Older Person and Effects on Dynamic Cerebral Autoregulation
Remote Ischaemic Conditioning (RIC) is the process of inducing short periods of ischaemia in a limb with the aim of improving vascular health systemically.
- Conditions
- Cerebral Autoregulation, Blood Pressure, Dynamic Cerebral Autoregulation
- Trial name
- RICE-DCA (NCT07179887)
- Testing
- Remote Ischaemic Conditioning
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Myocardial Infarction
Effect of Beta-blocker on Cardioprotective Effect of Remote Ischemic Conditioning
Remote ischemic conditioning has been shown to protect myocardium from ischemia-reperfusion injury during cardiac intervention or cardiac surgery.
- Trial name
- NCT03169426
- Testing
- Beta Blockers Carvedilol Phosphate
- Where
- South Korea
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Spinal Cord Injuries, Amyotrophic Lateral Sclerosis
Effects of Remote Ischemic Conditioning on Hand Use in Individuals With SCI and ALS
Rehabilitation interventions such as physical training and neural stimulation after spinal cord injury (SCI) have been shown to increase neural plasticity.
- Trial name
- NCT03851302
- Testing
- Active Remote Ischemic Conditioning, Isometric hand exercise
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Bronx VA Medical Center
Acute Stroke
Ischemic Conditioning During Air tRansport Save penUmbral Tissue
The purpose of this study is to demonstrate the feasibility of performing remote limb ischemic conditioning (RLIC) using the Doctormate device, a special blood pressure device used to perform RLIC, on patients with acute ischemic…
- Trial name
- ICARUS (NCT03481205)
- Testing
- Ischemic conditioning device
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Enrique Leira
Healthy, Young Adults
Remote Limb Ischemic Conditioning to Enhance Learning and Muscle Strength in Healthy Young Adults
The purpose of this research study is to determine if remote limb ischemic conditioning (RLIC) can enhance learning of a motor (balance) and an ecologically valid, complex cognitive-motor (driving) task, and increase skeletal…
- Trial name
- NCT03512028
- Testing
- RLIC, Muscle strength training, Driving training
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Hypercholesteremia, Endothelial Dysfunction
The Effect of Remote Ischemic Conditioning in Patients With Hypercholesterolemia
There is an on-going discussion weather remote ischemic conditioning (RIC) is effective in limiting the damage of reperfusion injury in STEMI patients.
- Trial name
- NCT05164185
- Testing
- Remote ischemic conditioning
- Where
- Sweden
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Adult
Effects of RIC on Cognitive Function and Blood Oxygen Levels in Unacclimatized Adult at High Altitude
Several studies have shown cognitive impairment such as memory, perception and learning skill during ascent to high altitudes. However, few studies have directly investigated the effect of high altitudes exposure on attention-a…
- Trial name
- NCT03728114
- Testing
- RIC
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences