Clinical trials: Remission
Inflammatory Bowel Diseases, Remission
Social and Demographic Determinants of Fatigue in Patients With Inflammatory Bowel Disease in Remission
The aim of this observational study is to identify the social and demographic determinants of fatigue in patients with inflammatory bowel disease in remission.
- Conditions
- Inflammatory Bowel Diseases, Remission, Fatigue
- Trial name
- SOFA (NCT06186999)
- Where
- 4 sites in France
- Volunteers
- 208 people
- Sponsor
- University Hospital, Grenoble
Hematologic Malignancy, GvHD
Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)
The purpose of this Phase 1, first in human open-label study is to assess the safety and tolerability of TRX-103 in patients with hematological malignancies undergoing HLA-mismatched related or unrelated hematopoietic stem cell…
- Conditions
- Hematologic Malignancy, GvHD, GVHD,Acute, GVHD, Chronic
- Trial name
- NCT06462365
- Testing
- TRX103
- Where
- 5 sites in United States
- Volunteers
- 36 people
- Sponsor
- Tr1X, Inc.
Acute Lymphoblastic Leukemia (ALL) in Complete Remission, Acute Myeloid Leukemia (AML) in Remission
Comparing Post-Transplant Cyclophosphamide As GVHD Prophylaxis to Standard of Care for Acute Leukemia Patients
This randomized clinical trial will evaluate two approaches of GvHD prophylaxis; the standard of care GVHD prophylaxis regimen (methotrexate/calcineurin inhibitors) and post-transplant cyclophosphamide with calcineurin inhibitors…
- Trial name
- PTCy-PMAT (NCT04314219)
- Testing
- Cyclophosphamide 50mg, Methotrexate
- Where
- Saudi Arabia
- Volunteers
- 264 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Cognitive Remediation, Cognitive Impairment
Internet-delivered Intervention Targeting Residual Cognitive Symptoms After Major Depressive Disorder
Background: Cognitive impairment and difficulties are frequently observed in individuals suffering from major depressive disorder. These impairments and difficulties can persist into remission as residual cognitive symptoms.
- Conditions
- Cognitive Remediation, Cognitive Impairment, Major Depression in Remission
- Trial name
- RestDep (NCT04864353)
- Testing
- RestDep: Internet-delivered intervention targeting residual cognitive symptoms
- Where
- Norway
- Volunteers
- 44 people
- Sponsor
- Haukeland University Hospital
Disease Activity, Remission of Ulcerative Colitis
Maresin-1 and Resolvin-D1 Levels and Disease Activity in Ulcerative Colitis
Specialized pro-resolving mediators (SPMs), which are typically thought to be formed via consecutive steps of oxidation of polyenoic fatty acids, have been shown to suppress inflammation and promote timely resolution of…
- Conditions
- Disease Activity, Remission of Ulcerative Colitis, Ulcerative Colitis Flare
- Trial name
- NCT06652464
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Adult Acute Lymphoblastic Leukemia in Remission
Vaccine Therapy in Reducing the Frequency of Cytomegalovirus Events in Patients With Hematologic Malignancies Undergoing Donor Stem Cell Transplant
This randomized phase II trial studies how well vaccine therapy works in reducing the frequency of cytomegalovirus severe infections (events) in patients with hematologic malignancies undergoing donor stem cell transplant.
- Conditions
- Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission, Adult Hodgkin Lymphoma
- Trial name
- NCT02396134
- Testing
- CMVpp65-A*0201 peptide vaccine, Laboratory Biomarker Analysis
- Where
- 5 sites in United States
- Volunteers
- 61 people
- Sponsor
- City of Hope Medical Center
Type 2 Diabetes Mellitus Remission
Type 2 Diabetes Remission
The study aims to establish a cohort of patients with type 2 diabetes (T2D) who have achieved remission through lifestyle intervention or bariatric surgery.
- Trial name
- NCT06177210
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Hodgkin Lymphoma in Remission
Study of Epigenetic and Inflammatory Markers of Accelerated Biological Ageing in the Follow up of Patients With Hodgkin's Lymphoma
Study design: It is a monocentric and exploratory study, experimental on human tissues in vitro which involves the analysis of peripheral blood in patients with Hodgkin's lymphomas with the following characteristics: in complete…
- Trial name
- MEPI-AGE (NCT06761274)
- Testing
- peripheral blood sampling
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Acute Myeloid Leukemia (AML) in Remission, Stem Cell Transplantation
Studying Conditioning Regimen In Pediatric Transplantation - AML , SCRIPT-AML
It is a randomized phase 3 study comparing two conditioning regimens in children with Acute Myeloid Leukemia, AML, undergoing allogenic stem cell transplantation.
- Trial name
- SCRIPT-AML (NCT05477589)
- Testing
- busulfan, cyclophosphamide and melphalan, BuCyMel, clofarabine, fludarabine and busulfan, CloFluBu
- Where
- 17 sites in Belgium, Denmark and 8 more
- Volunteers
- 170 people
- Sponsor
- Vastra Gotaland Region
Leukemia, Leukemia, Myeloid
Natural Killer Cell (CYNK-001) Infusions in Adults with AML
This study will find the maximum tolerated dose or the maximum planned dose of CYNK-001 which contains natural killer (NK) cells derived from human placental CD34+ cells and culture-expanded.
- Conditions
- Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, Acute, Neoplasms by Histologic Type
- Trial name
- CYNK001AML01 (NCT04310592)
- Testing
- CYNK-001
- Where
- 10 sites in United States
- Volunteers
- 27 people
- Sponsor
- Celularity Incorporated
Major Depressive Disorder, Recurrent, in Remission
Light and Ion Maintenance In Treatment for Depression (LIMIT-D): Feasibility Study
Antidepressants are widely used as first-line treatments for major depressive disorder (MDD). Clinical guidelines recommend 6-24 months of "maintenance" antidepressant treatment, after patients achieve symptom remission, to…
- Trial name
- NCT05423275
- Testing
- Negative ion therapy, Light therapy
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Adult Acute Myeloid Leukemia in Remission
Nivolumab in AML in Remission at High Risk for Relapse
This phase II trial studies how well nivolumab works in treating patients with acute myeloid leukemia that has decreased or disappeared but may still be in the body (remission), and is at high risk for returning (relapse).
- Conditions
- Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome, Adult Acute Myeloid Leukemia in Remission, Blasts Under 10 Percent of Bone Marrow Nucleated Cells, Therapy-Related Myeloid Neoplasm
- Trial name
- NCT02532231
- Testing
- Laboratory Biomarker Analysis, Nivolumab
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- M.D. Anderson Cancer Center
Alveolar Bone Resorption
Guided Bone Regeneration in Alveolar Socket
Following tooth extraction, volumetric changes in the soft and hard tissues of the extraction site are expected to occur with considerable resorption of the alveolar bone in both the vertical and the horizontal dimensions.
- Trial name
- GBR_socket (NCT05577663)
- Testing
- Routine treatment of the extraction socket, Socket seal technique by a free gingival graft, Socket seal technique using a synthetic resorbable membrane
- Where
- Greece
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Ulcerative Colitis in Remission
Evaluation of ProLife 10 FORTE on Gut Microbiota Composition in UC Patients
This clinical trial aims to learn if the probiotic Prolife 10 Forte could improve the Gut Microbiota composition of Ulcerative colitis patients during the remission phase.
- Trial name
- ProZ-UC (NCT06642883)
- Testing
- Prolife
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University of Padova
Ulcerative Colitis in Remission
Effect of Procyanidins in Leaky Gut Repairing in IBD
The goal of this clinical trial is to learn if the Grape Seed Extract Ecovitis, featuring low monomeric catechins content and a high concentration of oligo-polymeric procyanidins, could modulate the Gut Microbiota composition of…
- Trial name
- EcoVitis (NCT06576700)
- Testing
- Grape Seed Extracts
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- University of Padova
Crohn Disease, Inflammatory Bowel Diseases
Investigation of VAP-1 Expression and Tissue Blood Flow by PET-MRI in Patients With Crohn's Disease
This is an observational, single center, imaging study. The CD patients with active disease will be assessed by [68Ga]Ga-DOTA-Siglec-9 and [15O]H2O PET/MRE.
- Conditions
- Crohn Disease, Inflammatory Bowel Diseases, Crohn Disease of Small Intestine, Crohn Colitis
- Trial name
- VAP-PET (NCT06555042)
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Turku University Hospital
Recurrent Low Back Pain, Remission
Changing Trunk Muscle Activation in Patients With Recurrent Low Back Pain in Remission
The first aim of the study is to investigate the effects of a single therapy session on trunk muscle activation and lumbopelvic sensorimotor control in persons with recurrent low back pain in remission.
- Trial name
- MAS (NCT06452030)
- Testing
- Specific sensorimotor control training, Aspecific extension training, Fascia training
- Where
- Belgium
- Volunteers
- 55 people
- Sponsor
- University Ghent
Acute Lymphoblastic Leukemia, in Relapse, Acute Lymphoblastic Leukemia With Failed Remission
CD19/CD22 CAR-T Cells in Adults With R/R ALL or NHL
This study examines the safety, tolerability and preliminary efficacy of anti-CD19 /CD22 CAR T cells (KQ-2002)manufactured on-site in adults with relapsed or refractory CD19+ B cell acute lymphoblastic leukemia or CD19+ B cell…
- Conditions
- Acute Lymphoblastic Leukemia, in Relapse, Acute Lymphoblastic Leukemia With Failed Remission, B-cell Lymphoma Refractory, B-cell Lymphoma Recurrent
- Trial name
- NCT06445803
- Testing
- KQ-2002 CAR-T cells （CD19/CD22 CAR T-Cells）
- Where
- 2 sites in China
- Volunteers
- 48 people
- Sponsor
- Rong Tao
Major Depression in Remission
Feasibility of Adherence to Light Therapy
In this feasibility study, we propose an important question: What factors will affect participant adherence to the daily use of light therapy for maintenance treatment of depression? To answer this question, we will conduct a…
- Trial name
- NCT04944758
- Testing
- Light therapy
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of British Columbia
Graves Disease, Graves' Disease in Remission
Graves' Disease Induced by Epstein-Barr Virus Lytic Reactivation
Previous studies have proved that the lytic reactivation of latent Epstein-Barr virus (EBV) was significantly associated with the onset of Graves'disease (GD), however, the morbidity of GD and recurrence rate of hyperthyroidism…
- Conditions
- Graves Disease, Graves' Disease in Remission, Epstein-Barr Virus
- Trial name
- NCT06426758
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xiao-Ming Mao