Clinical trials: Remifentanil
Anesthetic Sparing
The Effects of Dexmedetomidine on Intravenous Anesthetic Requirements for Children Undergoing Dental Procedures
The investigators propose to determine the propofol and remifentanil sparing effects of a single dose of dexmedetomidine in the dental population.
- Trial name
- Dexmed-PRS (NCT03422978)
- Testing
- Dexmedetomidine, Normal saline
- Where
- Canada
- Volunteers
- 88 people
- Sponsor
- University of British Columbia
Gynecological Laparoscopy
Pain Relief by Intra-Peritoneal Nebulization of Ropivacaine Under Remifentanil Anesthesia for Gynecological Laparoscopy
In our prospective, randomized, placebo controlled and double-blinded study we will study the efficacy of intraperitoneal ropivacaine nebulization on pain relief during gynecologic laparoscopic surgery.
- Trial name
- PSDR (NCT00927979)
- Testing
- 10 mLRopivacaine 1%, Water for injection, 10 mL Ropivacaine 1%
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Anesthesia, Neurotoxicity
A Study to Compare the Long-term Outcomes After Two Different Anaesthetics
There is considerable evidence that most general anaesthetics modulate brain development in animal studies. The impact is greater with longer durations of exposure and in younger animals.
- Conditions
- Anesthesia, Neurotoxicity, Child Development
- Trial name
- TREX (NCT03089905)
- Testing
- Sevoflurane, Remifentanil, Dexmedetomidine
- Where
- 21 sites in United States, Australia and 2 more
- Volunteers
- 450 people
- Sponsor
- Murdoch Childrens Research Institute
Anesthesia-induced Negative Hemodynamic Effects
Atropine-effect During Propofol/Remifentanil Induction
Remifentanil is a widely used potent intravenous opioid with the advantage of having a short time of action. Compared to other opiates however remifentanil generates more intense hemodynamic side-effects.
- Trial name
- NCT01871922
- Testing
- Atropine
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- University Medical Center Groningen
Diastolic Dysfunction
Effects of Remifentanil on Cardiac Function in Patients With Diastolic Dysfunction
In this study ASA 1, 2 individuals with grade 1 or 2 diastolic dysfunction will be recruited to assess the effects of Remifentanil infusion on left ventricular function evaluated with transthoracic echocardiagraphy.
- Trial name
- NCT04117009
- Testing
- Remifentanil 2 MG, Echocardiographic evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Yeditepe University
Intubation Complication
Impact of a Intra-tracheal Intubation With Curarization or Without Curarization
VHIntubation is a French monocentric and observational study that will assess the impact of two intra-tracheal intubation preparation procedures (curarization versus remifentanil) on the voice, using the Voice Handicap Index…
- Trial name
- VHIntubation (NCT04364633)
- Testing
- Voice Handicap Questionnaire (VHI)
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Nantes University Hospital
Aortic Diseases, Abdominal
Opioid-potentiated Volative Anaesthetic Vs. Remifentanil And Propofol During Abdominal Aortic Aneurysm Surgery
Comparing 2 different anaesthetic methods during abdominal aortic aneurysm surgery. The patients will be followed up 30 days postoperative. Number of patients included will be 200. Perioperative details will be analyzed.
- Conditions
- Aortic Diseases, Abdominal, Aneurysm, Surgery
- Trial name
- ABSENT (NCT00538421)
- Testing
- Propofol, Sevoflurane
- Where
- Norway
- Volunteers
- 193 people
- Sponsor
- Sykehuset i Vestfold HF
Emergence Delirium
Emergence Delirium in Children: Total Intravenous Anesthesia With Propofol and Remifentanil Versus Inhalational Sevoflurane Anesthesia
Emergence delirium (ED) refers to a wide variety of behavioural disturbances that are commonly seen in children following emergence from anesthesia.
- Trial name
- NCT00885443
- Testing
- Propofol, sevoflurane
- Where
- Canada
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Postoperative Sedation
Target-controlled Infusion of Propofol and Remifentanil for Postoperative Sedation Guided by the Bispectral Index
This prospective randomized study evaluates the effectiveness of a closed-loop anesthesia system during the postoperative period.
- Trial name
- NCT00393003
- Testing
- Closed-loop anesthesia system
- Where
- 2 sites in France
- Volunteers
- 32 people
- Sponsor
- Hopital Foch
Other Complications of Surgical and Medical Procedures
Comparison of the Effects of Nicardipine and Remifentanil on Surgical Visual Field
In the present study, the purpose was to compare the effects of Nicardipine and Remifentanil on surgical visual field and hemodynamic parameters in microscopic tympanomastoidectomy cases with Controlled Hypotension (CH).
- Trial name
- NCT06130527
- Testing
- Nicardipine, Remifentanil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Erol Karaaslan
Patients Undergoing Laparoscopic Gastrectomy
Effect of Nefopam on Remifentanil Induced Postoperative Hyperalgesia
Opioids has been reported to cause hyperalgesia. Opioid induced hyperalgesia (OIH) is defined as paradoxically lowering the threshold of pain after the exposure of opioid.
- Trial name
- NCT01732666
- Testing
- Nefopam, low dose remifentanil, high dose remifentanil
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Yonsei University
Analgesia
Correlation Between qNOX and Analgesia Nociception Index (ANI) Values During General Anesthesia
qNOX and ANI are two indexes evaluting the analgesia conduction during general anesthesia. No trials have compared them, so with this trial authors want to explore the correlations between them.
- Trial name
- ANI (NCT06351072)
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of Padova
Intraoperative Pain, Postoperative Pain
PECS-II vs ESP in Nociception Level Index Guided Breast Surgery
Background: Breast surgery is often associated with significant perioperative pain. While systemic opioids are commonly used, their side effects (nausea, vomiting, respiratory depression, delayed recovery) have encouraged the…
- Trial name
- NOL (NCT07002541)
- Testing
- PECS II block, ESP block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Koç University
Anesthesia, Total Intravenous Anesthesia
The Effect of Anesthetic Methods on Gastrointestinal Motility
The goal of this randomized controlled single blinded study is to compare the effect of the type of anesthesia on gastrointestinal motility in patients scheduled for laparoscopic sleeve gastrectomy.
- Trial name
- NCT05951686
- Testing
- Desflurane, Remifentanil infusion, Fresh gas
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Bozyaka Training and Research Hospital
Intravenous Lidocaine and Immunity
Impact of Intravenous Lidocaine During Colorectal Surgery on Pain and Immune Functions
This study evaluates the impact of intraoperative intravenous lidocaine administered during laparoscopic colorectal surgery on the intraoperative remifentanil consumption as well as postoperative pain and opioid requirements.
- Trial name
- NCT03410836
- Testing
- intravenous lidocaine (IVL)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Cholecystolithiasis
Dual-Loop Target Controlled Infusion in Laparoscopic Cholecystectomy (DLTCI)
Laparoscopic Cholecystectomy applied to Artificial pneumoperitoneum and the extent of Surgical stimulation cause the wave of hemodynamics increase vigorously, which make it difficult to judge the depth of anesthesia according to…
- Trial name
- DLTCI (NCT02116985)
- Testing
- Dual-loop TCI, manual
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Neuromuscular Block
Can Adequacy of Anesthesia Depth and Quality of Recovery be Influenced by the Level of Neuromuscular Blockade?
The investigators hypothesize that an anesthetic protocol maintaining deep neuromuscular block throughout the entire surgical procedure followed by sugammadex reversal, would suppress EMG activity and result in improved…
- Trial name
- NCT02484651
- Testing
- Sugammadex, Rocuronium
- Where
- Portugal
- Volunteers
- 70 people
- Sponsor
- Centro Hospitalar do Porto
Intra-tracheal Intubation
Assessment of Remifentanil for Rapid Sequence Induction and Intubation in Full Stomach Patient Compared to Muscle Relaxant
REMICrush is a French multicentric non inferiority simple blind randomized clinical trial that will compare the use of Remifentanil to muscle relaxant (reference treatment) for anesthetic rapid sequence intubation in terms of…
- Trial name
- REMICRUSH (NCT03960801)
- Testing
- Remifentanil group, neuromuscular blockade group
- Where
- 13 sites in France
- Volunteers
- 1,150 people
- Sponsor
- Nantes University Hospital
Mechanical Ventilation
Rapip Study: Clinical Trial on Remifentanyl for Analgesia and Sedation of Ventilated Neonates and Infants
It shall be investigated whether ventilated neonates and infants with a remifentanyl based analgesia and sedation can be extubated faster after discontinuation of the opioid infusion compared to neonates and infants with a…
- Trial name
- NCT00419601
- Testing
- Remifentanyl, Fentanyl
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- University of Cologne
Sedative Adverse Reaction
Target Controlled Infusion Using Propofol and Remifentanil for Moderate Sedation in Dentistry
The purpose of this university study is to evaluate the use of an advanced dental sedation technique involving two syringe-type pumps called Target Controlled Infusion (TCI) pumps.
- Trial name
- NCT03995134
- Testing
- Propofol and Remifentanil administered by TCI pump
- Where
- 2 sites in Canada, New Zealand
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Alberta