Clinical trials: Remifentanil
Pain Threshold, Surgery
The Effect of Remifentanil on the Objectively Measured Pressure Pain Threshold
It is a clinical study investigating the relationship between objectively measured pain threshold and the need for escalating doses of remifentanyl opioids. This study is expected to include approximately 40 participants.
- Conditions
- Pain Threshold, Surgery, Postoperative Pain, Intravenous Anesthesia
- Trial name
- NCT07568405
- Testing
- Pressure pain theshold measured under remifentanil (ultiva®) infusion, Postoperative PCA IV morphine (Sterop®) consumption and adverse events history
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Université Libre de Bruxelles
Spinal Fusion
Remifentanil Propofol Infusion in Pediatric Spinal Surgery
Total intravenous anesthesia(TIVA) is a commonly used anesthetic technique. Although TIVA can be accomplished with a variety of drug combinations, infusions of Propofol and Remifentanil are often used with dosage adjusted…
- Trial name
- NCT00761072
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Children's Hospital of Philadelphia
Anesthesia
Role of LIDOCAINE IN Pediatric Cochlear Implant Surgery
The stapedius reflex protects the ear from the loud noise. The measurement of the intraoperative electrically evoked stapedial reflex threshold (ESRT) during pediatric cochlear implants (CIs) is used to confirm that the implant…
- Trial name
- NCT04194294
- Testing
- Lidocaine, Na CL 0.9%
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Wahba bakhet
Pain, Postoperative, Bariatric Surgery Candidate
Ketamine for Postoperative Pain in Bariatric Surgery
The aim of this study was to evaluate an effect of pre - incisional single injection of low-dose ketamine on postoperative pain after remifentanil infusion in patients undergoing laparoscopic gastric bypass and gastric plication…
- Trial name
- KEPOBA (NCT03389022)
- Testing
- Ketamine, Saline
- Volunteers
- 64 people
- Sponsor
- Lithuanian University of Health Sciences
Hyperalgesia
The Effect of Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers
Treatment of chronic pain is a major clinical challenge since chronic pain is frequent and leads to deterioration of quality of life.
- Trial name
- RemiSun 1 (NCT00811837)
- Testing
- Midazolam, Remifentanil
- Where
- Austria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Neuralgia, Postherpetic
Effect of Opioids in Neuropathic Pain in Postherpetic Patients
Postherpetic neuralgia (PHN) is often associated with pain and sensory changes and is the leading type of neuropathic pain in modern clinical pain research.
- Trial name
- VHPRG-HDRPH (NCT01102101)
- Testing
- Remifentanil
- Where
- 2 sites in Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Chronic SSRI/SNRI Use and Intraoperative Propofol Requirements
The Effect of Chronic ssrı/snrı Antidepressant Treatment on Propofol Consumption in Elective Spine Surgery
The goal of this observational study is to learn whether long-term use of selective serotonin reuptake inhibitor (SSRI) or serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressants is related to the amount of propofol…
- Trial name
- NCT07822295
- Where
- Turkey (Türkiye)
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Autonomic Nervous System Activity
Vagotonic Effect of Remifentanil and Autonomic Nervous System Activity.
Remifentanil (RMFNT) is a very short active opioid, used for analgesia during general anaesthesia and for analgesic and sedative effect in intensive care units (ICU) patients.
- Trial name
- NCT01714388
- Testing
- Remifentanil
- Where
- Poland
- Volunteers
- 70 people
- Sponsor
- Medical University of Gdansk
Ibuprofen, Remifentanil
Prevention of Remifentanil-induced Postoperative Hyperalgesia With Intravenous Ibuprofen
Postoperative hyperalgesia has been reported after intraoperative administration of small or high-dose remifentanil. Cyclooxygenase inhibitor exhibit preventive effects on the development of opioid-induced hyperalgesia.
- Conditions
- Ibuprofen, Remifentanil, Hyperalgesia, Pain, Postoperative
- Trial name
- NCT02243254
- Testing
- high dose remifentanil, Ibuprofen, low dose remifentanil
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Seoul National University Hospital
Pain, Procedural
ANI and Remifentanil in Skull Pin Fixation.
Forty patients were enrolled, and all patients used total intravenous anesthesia (remifentanil-propofol based total intravenous analgesia) as anesthesia induction and maintenance.
- Trial name
- NCT05125328
- Testing
- Remifentanil
- Where
- Taiwan
- Volunteers
- 27 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Postoperative Pain
Propofol Versus Sevoflurane on Acute Postoperative Pain
This study was performed to compare the acute postoperative pain intensity and opioid consumption after total shoulder arthroplasty between propofol-remifentanil and sevoflurane-remifentanil anesthesia.
- Trial name
- NCT04333992
- Testing
- propofol and remifentanil, sevoflurane and remifentanil
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Yeungnam University College of Medicine
Delirium
The Effect of Remifentanil Infusion During Emergence on the Incidence of Emergence Delirium
The aim of the present study is to assess the effect of postoperative remifentanil infusion on the incidence of emergence agitation in preschool-aged children undergoing strabismus surgery with sevoflurane anaesthesia.
- Trial name
- NCT02108795
- Testing
- Remifentanil
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Yeungnam University College of Medicine
Septorhinoplasty, Remifentanil Consumption
Effect of Bilateral Maxillary Block on Intraoperative Remifentanil Consumption
The maxillary nerve block is a regional anesthetic technique targeting the sensory distribution of the maxillary nerve and is particularly preferred to provide analgesia in midfacial and maxillary surgical procedures.
- Conditions
- Septorhinoplasty, Remifentanil Consumption, Maxillary Block
- Trial name
- NCT07608861
- Testing
- Preoperative Maxillary Block, Postoperative Maxillary Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Anesthesia, Intravenous, Electroencephalography
Remifentanil Effect on Burst Suppression Ratio
The goal of this clinical trial is to determine whether remifentanil has a facilitating effect on the generation of burst suppression by propofol in adult patients (18-60 years) candidates for elective surgery who require…
- Conditions
- Anesthesia, Intravenous, Electroencephalography, Burst Suppression
- Trial name
- NCT06237101
- Testing
- High dose of remifentanil, Medium dose of remifentanil
- Where
- 2 sites in Chile
- Volunteers
- 20 people
- Sponsor
- University of Chile
Nociceptive Pain, Goal-directed Therapy
Nol-Index Guided Remifentanil Analgesia Versus Standard Analgesia During Moderate-to-High Risk Cardiovascular Surgery
This study will investigate the potential of guiding remifentanil analgesia during cardiac and vascular surgery in moderate to high risk patients requiring general anesthesia.
- Conditions
- Nociceptive Pain, Goal-directed Therapy, Hemodynamic Instability, Nol-Index
- Trial name
- NCT04137991
- Testing
- Nol-Index guided analgesia, Standard Analgesia
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Erasme University Hospital
Lung Cancer
Safety Evaluation of Dexmedetomidine for EBUS-TBNA
Lung cancer is the second most commonly diagnosed primary neoplasia in Canada accounting for 22 865 new cases in 2007. Recent randomized trials have shown a significantly better diagnostic yield and fewer unnecessary…
- Trial name
- EBUSed (NCT01381627)
- Testing
- Remifentanil, Dexmedetomidine
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Hyperventilation, Aneurysmal Subarachnoid Hemorrhage
Drug Intervention of Spontaneous Hyperventilation in Patients With Aneurysmal Subarachnoid Hemorrhage
Although spontaneous hyperventilation patients with aneurysmal subarachnoid hemorrhage closely associated with poor outcomes, the standard therapy remains unavailable.
- Conditions
- Hyperventilation, Aneurysmal Subarachnoid Hemorrhage, Cerebral Blood Flow
- Trial name
- NCT04940273
- Testing
- Remifentanil Injection [Ultiva]
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Capital Medical University
Patients Undergoing Major Abdominal Surgery, Postoperative Confusion
Effect of Remifentanil on Postoperative Cognition Function in Patients Undergoing Major Abdominal Surgery
The purpose of this study is to investigate the effects of two different analgesic methods (Fentanyl vs Remifentanil) during major abdominal surgery on postoperative cognitive status of patients.
- Trial name
- NCT01627873
- Testing
- Remifentanil, Fentanyl
- Where
- Italy
- Volunteers
- 622 people
- Sponsor
- Catholic University of the Sacred Heart
Hypertensive Disease, Pain, Postoperative
Effect of Acute Arterial Hypertension on Morphine's Requirements and Postsurgical Pain.
The purpose of this randomized clinical trial is to evaluate the effect of acute arterial hypertension maintained during surgery on morphine's requirements in patients undergoing laparoscopic cholecystectomy
- Trial name
- NCT01897155
- Testing
- SBP 20-30% over baseline, SBP 20-30% under baseline
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Pain, Head and Neck Disorder
Effect of Remifentanil on the Recovery Profile After Prolonged Head and Neck Surgery
Opioid tolerance in the perioperative period is inevitable especially with ultra-short acting agents such as remifentanil. Existing evidence had shown that opioid induced hyperalgesia due to neuroplastic changes in the central as…
- Trial name
- NCT02416752
- Testing
- Remifentanil, choice of intra-operative opioids were left to the discretion of anesthesiologist
- Where
- Singapore
- Volunteers
- 222 people
- Sponsor
- Singapore General Hospital